EKS-LAC-00264

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LAC-00264

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	295.9	2.4E-88	16	270	255

Status

Unreviewed

Ensembl Protein

ENSLACP00000006413

UniProt Accession

H3A9U2;

Protein Name

Protein Synonyms/Alias

Gene Name

PRKAA2

Gene Synonyms/Alias

PRKAA2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000005690	ENSLACP00000006413	ENSLACT00000006466

Organism

Latimeria chalumnae

Functional Description

Protein Length

553

Protein Sequence
(FASTA)

MAEKQKHDGR VKIGHYVLGD TLGVGTFGKV KRLVGEHQLT GHKVAVKILN RHKIRSLDVV 60

GKIKREIQNL KLFRHPHIIK LYSILAIGPD FYLVELAHSG SALARLHCKL ERVEEAEARR 120

LFQQIISAVD YCHRHMVVHR DLKPENVLLD AHMNAKIADF GLSNMMSDGE FLRTSCGSPN 180

YAAPEVISGR LYAGPEVDIW SCGVILYALL CGTLPFDDEH VPTLFKKIRG GVFYIPEYLN 240

HSVASLLMHM LQVDPLKRAT IKDIREHEWF KQDLPTYLFP EDPAYDANVI DDEAVREVCE 300

KFECTESEVM NSLYSGDPQD QLAVAYHLVI DNRRIMNQAS EFYLASSPPT SSFMDDSSMH 360

IPPGVKPHPE RMPPLIADSP KSRCPLDALN TTKPKPLAVK KAKWHLGIRS QSKPYDIMAE 420

VYRAMKQLDY EWKVANPYHL RVRRKNPVTG NYVKMSLQLY QVDNRSYLLD FKSIDDDIME 480

QKSGSSTPQR SGSAAGLHRP RLSIDATIAD TQSLSGSLSG SFTASVTSIT PRLGSHTMDF 540

FEMCASLITT LAR 553

Nucleotide Sequence
(FASTA)

ATGGCTGAGA AGCAGAAGCA CGACGGCAGA GTTAAAATAG GACATTACGT CTTGGGAGAC 60

ACTCTTGGGG TCGGAACCTT TGGAAAAGTA AAGAGATTAG TTGGAGAGCA CCAGCTAACG 120

GGACACAAGG TTGCAGTGAA AATTCTGAAC CGACACAAAA TTCGCAGTTT GGATGTGGTC 180

GGAAAGATCA AACGAGAAAT TCAGAACCTA AAACTTTTCC GCCATCCACA CATTATCAAG 240

CTCTACAGTA TATTAGCAAT AGGACCAGAC TTTTATTTAG TTGAGTTAGC TCATTCAGGG 300

TCAGCCTTAG CCAGGTTACA CTGTAAATTA GAAAGAGTTG AAGAGGCTGA GGCACGCCGA 360

CTTTTCCAAC AGATTATCTC TGCTGTGGAT TATTGCCACA GGCATATGGT GGTTCACCGT 420

GACCTGAAAC CAGAGAACGT TCTACTAGAT GCACACATGA ATGCCAAGAT AGCTGACTTC 480

GGTCTGTCTA ATATGATGTC AGATGGTGAA TTTTTACGAA CCAGCTGTGG CTCACCGAAC 540

TATGCAGCAC CCGAGGTTAT TTCAGGAAGG TTGTATGCAG GCCCCGAAGT TGATATCTGG 600

AGCTGTGGTG TAATCTTATA TGCCCTTCTC TGTGGGACAC TCCCATTTGA TGATGAACAT 660

GTTCCTACTC TGTTCAAGAA GATTCGTGGA GGAGTGTTTT ATATTCCTGA GTACCTGAAC 720

CACTCAGTAG CCAGTCTTCT TATGCACATG CTACAGGTTG ACCCACTCAA AAGGGCAACC 780

ATAAAAGATA TACGAGAACA CGAGTGGTTT AAGCAGGATT TGCCAACTTA TTTATTTCCT 840

GAGGACCCTG CGTATGATGC TAATGTAATT GACGATGAAG CAGTAAGGGA GGTTTGTGAG 900

AAGTTTGAAT GTACAGAATC TGAGGTCATG AACAGCCTGT ACAGTGGTGA CCCTCAGGAT 960

CAGCTTGCTG TGGCCTACCA CCTTGTTATT GACAATCGCA GAATCATGAA CCAGGCTAGT 1020

GAGTTTTACC TTGCCTCAAG TCCTCCAACA AGCTCATTTA TGGACGACAG CAGCATGCAC 1080

ATTCCACCAG GTGTAAAACC TCACCCTGAG CGAATGCCCC CTCTTATAGC AGACAGCCCT 1140

AAATCACGAT GCCCTCTGGA TGCTTTGAAC ACTACAAAAC CAAAACCACT GGCTGTGAAG 1200

AAAGCAAAGT GGCATCTGGG AATTCGGAGC CAAAGTAAAC CATATGATAT AATGGCAGAG 1260

GTGTACAGAG CAATGAAACA GCTGGATTAT GAATGGAAGG TGGCAAATCC GTATCATCTG 1320

AGGGTACGTC GAAAGAACCC AGTGACTGGG AATTATGTGA AGATGAGCTT ACAGCTATAC 1380

CAAGTTGATA ATCGCAGCTA CTTGTTGGAT TTCAAGAGCA TTGATGATGA TATCATGGAA 1440

CAGAAATCTG GCTCATCTAC ACCCCAGCGC TCCGGGTCAG CAGCTGGATT ACACAGACCT 1500

AGACTAAGCA TTGATGCTAC CATAGCTGAT ACTCAGTCAC TTAGTGGATC ACTCTCAGGC 1560

TCCTTCACAG CAAGTGTGAC TTCCATTACC CCACGCCTGG GCAGTCATAC AATGGATTTC 1620

TTTGAAATGT GTGCCAGTCT GATCACTACA TTGGCTCGCT GA 1662

Domain Profile

S: 1     ykllktlGegsfgkVkla..khketkekvavKiikkkkl.seeslekikrEieilkklkh  57

         y l++tlG g+fgkVk    +h++t++kvavKi++++k+ s + + kikrEi+ lk ++h

Q: 16    YVLGDTLGVGTFGKVKRLvgEHQLTGHKVAVKILNRHKIrSLDVVGKIKREIQNLKLFRH  75

         8899************7522688***************96667788**************

S: 58    pniikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhsk  117

         p+iikl++++    ++ylv    sg  L     + +r++e ear+lf+q++sav+Y+h++

Q: 76    PHIIKLYSILAIGPDFYLVELAHSGSALARLHCKLERVEEAEARRLFQQIISAVDYCHRH  135

         ******************98888888999999999*************************

S: 118   givHrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegp  177

          +vHrDlKpeN+lld+++n kiaDFGl+n++++g+ l+t+cGsp+YaaPe+++g+ Y gp

Q: 136   MVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGP  195

         ************************************************************

S: 178   kvDvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdp  237

         +vD+Ws+Gv+Lyal++g+lPfd+e++ +l++ki  g + ip++l+++++sLl ++L+vdp

Q: 196   EVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNHSVASLLMHMLQVDP  255

         ************************************************************

S: 238   ekRatieeilkhewl  252

          kRati++i++hew+

Q: 256   LKRATIKDIREHEWF  270

         **************7

Domain Sequence
(FASTA)

YVLGDTLGVG TFGKVKRLVG EHQLTGHKVA VKILNRHKIR SLDVVGKIKR EIQNLKLFRH 60

PHIIKLYSIL AIGPDFYLVE LAHSGSALAR LHCKLERVEE AEARRLFQQI ISAVDYCHRH 120

MVVHRDLKPE NVLLDAHMNA KIADFGLSNM MSDGEFLRTS CGSPNYAAPE VISGRLYAGP 180

EVDIWSCGVI LYALLCGTLP FDDEHVPTLF KKIRGGVFYI PEYLNHSVAS LLMHMLQVDP 240

LKRATIKDIR EHEWF 255

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013