EPS-LAC-00012

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-LAC-00012

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	158.9	8.6E-47	15	157	143

Status

Unreviewed

Ensembl Protein

ENSLACP00000006577

UniProt Accession

H3AAA6;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000005831	ENSLACP00000006577	ENSLACT00000006630

Organism

Latimeria chalumnae

Functional Description

Protein Length

359

Protein Sequence
(FASTA)

ELEQILQTRA LSCNHIDEVW PNLYLGDLVA AHDRYGLWKL GITHVLNAAH GKTFCHGCHD 60

FYGTSVDYHG VPANDLPEFD LTPYLYPAAE YIQKALNSPG GKILVHCAVG VSRSASLVLA 120

YLMIFHRFPL VDAIKTVKEH RWIFPNRGFL KQLRKLGAVM HLFQNIIPRS KSRKKENKGL 180

PTTETVSSAT PSVTEVEAII DGCRVASNHV TEVWPKLYLG DLIIAHDRKE LARLGITHVL 240

NSAHSAWCSK GDENFYGKDM HYYRIVAEDS VDFDLSVYFH PAADYIHSAL NSPNGKVLVH 300

CILGKSRSAS LVLAYLMIYH HHSLDDALRR LLSYRAISPN RGFLKQLRDL DMELRYKVK 359

Nucleotide Sequence
(FASTA)

GAGCTGGAAC AGATCTTGCA AACCCGTGCG CTCTCTTGCA ACCATATAGA TGAAGTGTGG 60

CCTAATCTCT ACCTAGGAGA CCTAGTCGCA GCCCATGACA GGTATGGCTT ATGGAAGCTG 120

GGAATCACCC ACGTGTTAAA CGCTGCTCAC GGGAAGACGT TCTGCCACGG GTGCCACGAC 180

TTTTACGGCA CAAGTGTGGA CTACCACGGT GTGCCAGCCA ATGACCTTCC TGAGTTTGAT 240

CTGACGCCAT ACCTCTATCC TGCAGCGGAG TACATTCAGA AGGCCTTGAA CAGCCCAGGT 300

GGTAAAATTC TGGTTCACTG TGCAGTGGGG GTGAGCCGGT CGGCCTCCCT GGTGCTTGCC 360

TACCTTATGA TCTTCCATCG CTTCCCACTG GTTGATGCCA TCAAGACCGT GAAGGAGCAC 420

CGCTGGATCT TCCCCAATCG GGGCTTCCTG AAACAGCTGC GGAAATTGGG TGCTGTCATG 480

CACCTGTTCC AAAACATCAT ACCCAGAAGT AAGAGCAGGA AAAAAGAAAA CAAGGGTCTG 540

CCTACAACTG AAACGGTCAG CTCCGCAACA CCCTCTGTCA CAGAGGTGGA AGCCATAATA 600

GACGGCTGCA GGGTGGCATC CAACCATGTC ACTGAAGTGT GGCCTAAACT ATATTTGGGA 660

GACCTAATAA TTGCCCATGA CAGGAAGGAG TTGGCAAGAC TTGGCATCAC TCATGTGTTG 720

AATTCTGCCC ACTCCGCTTG GTGCAGCAAA GGAGATGAGA ACTTCTATGG GAAGGACATG 780

CATTACTATA GAATAGTGGC TGAAGACTCG GTGGATTTCG ACCTGAGTGT GTATTTCCAT 840

CCTGCCGCTG ACTACATACA CAGTGCTCTC AATTCTCCTA ATGGAAAGGT GCTGGTTCAC 900

TGCATTCTGG GGAAAAGTAG ATCTGCCTCA TTGGTGTTGG CCTATCTGAT GATATACCAT 960

CACCATTCCC TGGACGACGC CCTCCGGAGG CTTCTCTCAT ACCGGGCAAT TTCCCCAAAC 1020

AGAGGCTTCC TGAAGCAGCT GCGGGATCTA GATATGGAGC TACGCTACAA AGTGAAA 1077

Domain Profile

S: 1     evteilpglylgdqataldrreLsklgitvvinaslsvikvqviPeylikkgityknipv  60

         +++e++p+lylgd   a dr+ L+klgit+v+na+++ + +++  +++  +++ y+++p+

Q: 15    HIDEVWPNLYLGDLVAAHDRYGLWKLGITHVLNAAHGKTFCHGCHDFY-GTSVDYHGVPA  73

         699********************************************9.99*********

S: 61    dDsdvtdllqyfdeaaefidea.kekggkvlvHCaaGvsRSatlvlaYLmkveglslsdA  119

         +D +++dl +y+ +aae+i++a +++ggk+lvHCa+GvsRSa lvlaYLm+++ + l+dA

Q: 74    NDLPEFDLTPYLYPAAEYIQKAlNSPGGKILVHCAVGVSRSASLVLAYLMIFHRFPLVDA  133

         *********************9999***********************************

S: 120   ieavkrkrpsiepnegfleQLlele  144

         i++vk++r +i pn+gfl+QL++l

Q: 134   IKTVKEHR-WIFPNRGFLKQLRKLG  157

         ********.************9875

Domain Sequence
(FASTA)

HIDEVWPNLY LGDLVAAHDR YGLWKLGITH VLNAAHGKTF CHGCHDFYGT SVDYHGVPAN 60

DLPEFDLTPY LYPAAEYIQK ALNSPGGKIL VHCAVGVSRS ASLVLAYLMI FHRFPLVDAI 120

KTVKEHRWIF PNRGFLKQLR KLG 143

Keyword

Complete proteome; Hydrolase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0004725	; F:protein tyrosine phosphatase activity
GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0035335	; P:peptidyl-tyrosine dephosphorylation

KEGG

InterPros

IPR020417	; Atypical_DUSP.
IPR020405	; Atypical_DUSP_famA.
IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR020422	; Dual-sp_phosphatase_subgr_cat.
IPR024950	; DUSP.
IPR000387	; Tyr/Dual-specificity_Pase.
IPR016130	; Tyr_Pase_AS.

Pfam

PF00782

; DSPc; 2.

SMARTs

SM00195

; DSPc; 2.

Prosites

PS00383	; TYR_PHOSPHATASE_1; 2.
PS50056	; TYR_PHOSPHATASE_2; 2.
PS50054	; TYR_PHOSPHATASE_DUAL; 2.

Prints

PR01908	; ADSPHPHTASE.
PR01909	; ADSPHPHTASEA.

Created Date

20-Feb-2013