EKS-LAC-00399

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LAC-00399

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/MLK	229.4	5.7E-68	167	411	245

Status

Unreviewed

Ensembl Protein

ENSLACP00000006792

UniProt Accession

H3AAX1;

Protein Name

Protein Synonyms/Alias

Gene Name

ILK

Gene Synonyms/Alias

ILK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000006027	ENSLACP00000006792	ENSLACT00000006849

Organism

Latimeria chalumnae

Functional Description

Protein Length

417

Protein Sequence
(FASTA)

DDHGFSPLHW ACREGRTNIV DMLIMRGARI NVMNRGDDTP LHLAASHGHR DIVQKLIQFK 60

ADVNAVNEHG NTPLHYACFW GQEEVAEDLL MNGGLVSICN KYGETPLDKA KLHLRDILKD 120

RAEKLGQSLT KVPYKDTFWK GTTRTRPRNG TLNKHAGIDF KQLSLSHKLN ENQSGEVLWR 180

GTYVSRALER GCMPSGYNPS LQEEFPKLRI FSHPNVLPVL GACQSPPAPH PIIITHWMPY 240

GSLYNVLHEG TNFVVDQMQA VKFALDIARG MAFLHTLEPL IPRHYLNSRS IMIDEDMTAR 300

ISMADVKFSF QCPGRMYAPA WVAPEALQKK PEEINRRSSD MWSFAVLLWE LVTREVPFAD 360

LSNMEIGMKV ALEGLRPTIP PGISPHICKL MKICMNEDPA KRPKFDMIVP ILEKMQD 417

Nucleotide Sequence
(FASTA)

GATGACCACG GTTTCAGCCC GCTGCACTGG GCGTGCCGGG AGGGCCGCAC CAACATAGTG 60

GACATGCTGA TAATGAGGGG CGCACGGATT AACGTCATGA ACCGGGGTGA CGACACCCCC 120

TTGCACCTGG CAGCCAGTCA CGGACACAGA GACATCGTGC AAAAGTTGAT TCAGTTTAAA 180

GCAGACGTCA ATGCCGTGAA TGAACATGGA AACACACCGC TACACTACGC CTGCTTCTGG 240

GGCCAGGAAG AGGTTGCAGA GGACCTCTTG ATGAACGGAG GGCTGGTCAG CATCTGTAAC 300

AAATATGGGG AGACACCATT GGACAAGGCG AAGCTGCACT TGCGGGACAT TTTAAAAGAT 360

CGGGCTGAGA AGTTGGGTCA GAGCCTGACC AAGGTGCCTT ACAAGGACAC GTTCTGGAAG 420

GGAACCACCC GCACGAGGCC ACGGAACGGC ACCCTGAACA AACATGCTGG GATCGACTTC 480

AAACAACTGA GTCTCAGTCA CAAGCTCAAC GAGAACCAGT CTGGAGAGGT ACTCTGGAGA 540

GGTACATACG TTAGCAGGGC TCTGGAACGT GGGTGCATGC CTTCTGGTTA TAATCCCAGT 600

CTGCAGGAGG AGTTTCCCAA ACTTAGGATT TTTTCTCACC CGAATGTGTT ACCGGTTTTG 660

GGGGCCTGCC AGTCTCCTCC TGCCCCCCAT CCCATTATCA TCACTCACTG GATGCCTTAC 720

GGCTCTCTCT ACAACGTCCT GCACGAGGGA ACAAATTTTG TAGTTGATCA GATGCAGGCG 780

GTGAAGTTTG CACTGGACAT TGCTCGGGGG ATGGCATTCC TACACACATT GGAGCCGCTA 840

ATTCCACGCC ACTATCTCAA CAGCAGGAGT ATCATGATTG ATGAAGATAT GACAGCTCGT 900

ATCAGCATGG CGGACGTGAA GTTCTCTTTC CAGTGTCCGG GACGCATGTA TGCACCAGCT 960

TGGGTGGCAC CAGAAGCCCT GCAGAAGAAG CCAGAGGAGA TAAACCGGCG GTCGTCGGAC 1020

ATGTGGAGCT TTGCCGTGCT GCTGTGGGAG CTGGTGACCC GCGAGGTGCC TTTCGCAGAC 1080

CTCTCCAACA TGGAGATTGG AATGAAGGTT GCTTTGGAAG GGCTGCGTCC CACAATCCCC 1140

CCGGGGATCT CCCCCCATAT CTGCAAACTG ATGAAGATCT GTATGAACGA GGATCCTGCC 1200

AAGAGACCAA AGTTTGACAT GATCGTGCCC ATCCTGGAAA AAATGCAGGA C 1251

Domain Profile

S: 5     eligsgafgkv.ykakwrkkevavKklreeaeekekleklereakllsklshpniiellG  63

         ++++++++g+v +++++ +     ++l++ ++ +    +l++e+ +l+ +shpn++ +lG

Q: 167   HKLNENQSGEVlWRGTYVS-----RALERGCMPSGYNPSLQEEFPKLRIFSHPNVLPVLG  221

         5666666666623333333.....466666777777889*********************

S: 64    vcleepn..lllvmeyveggsLsnvlhekskreidlevlvswalqiArGmaYLhseapkk  121

         +c+++p+   +++++++++gsL+nvlhe ++ ++d+ ++v++al+iArGma+Lh+ +p

Q: 222   ACQSPPAphPIIITHWMPYGSLYNVLHEGTNFVVDQMQAVKFALDIARGMAFLHTLEPL-  280

         *****997459*********************************************997.

S: 122   iihrdLksknvLlseekktlkicdFGtarelskstkmsaa.gtlawmaPEvlkeekvs..  178

         i ++ L+s+++++ +e++t++i++ +++++   s+++  + +++aw+aPE+l++++ +

Q: 281   IPRHYLNSRSIMI-DEDMTARISM-ADVKF---SFQCPGRmYAPAWVAPEALQKKPEEin  335

         *************.**********.88888...78999998************9998877

S: 179   .eksDvwSygvvLWelltrevPykdlselaiaykvalkglrlpipsscpeklkkLmkecw  237

          ++sD+wS++v+LWel+trevP++dls+++i +kval+glr++ip+ ++++++kLmk c+

Q: 336   rRSSDMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPHICKLMKICM  395

         899*********************************************************

S: 238   nedpekRpsfseivks  253

         nedp+kRp+f++iv +

Q: 396   NEDPAKRPKFDMIVPI  411

         *************986

Domain Sequence
(FASTA)

HKLNENQSGE VLWRGTYVSR ALERGCMPSG YNPSLQEEFP KLRIFSHPNV LPVLGACQSP 60

PAPHPIIITH WMPYGSLYNV LHEGTNFVVD QMQAVKFALD IARGMAFLHT LEPLIPRHYL 120

NSRSIMIDED MTARISMADV KFSFQCPGRM YAPAWVAPEA LQKKPEEINR RSSDMWSFAV 180

LLWELVTREV PFADLSNMEI GMKVALEGLR PTIPPGISPH ICKLMKICMN EDPAKRPKFD 240

MIVPI 245

Keyword

ANK repeat; Complete proteome; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity

KEGG

InterPros

IPR002110	; Ankyrin_rpt.
IPR020683	; Ankyrin_rpt-contain_dom.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.

Pfam

PF12796	; Ank_2; 1.
PF07714	; Pkinase_Tyr; 1.

SMARTs

SM00248

; ANK; 3.

Prosites

PS50297	; ANK_REP_REGION; 1.
PS50088	; ANK_REPEAT; 3.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013