EKS-LAC-00086

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LAC-00086

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/GSK	447.3	2.5E-134	96	379	284

Status

Unreviewed

Ensembl Protein

ENSLACP00000007367

UniProt Accession

H3ACJ6;

Protein Name

Protein Synonyms/Alias

Gene Name

GSK3A

Gene Synonyms/Alias

GSK3A;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000006537	ENSLACP00000007367	ENSLACT00000007428

Organism

Latimeria chalumnae

Functional Description

Protein Length

463

Protein Sequence
(FASTA)

MMSGRARTSS FADPPPTVTG SSAPGKPMVS AAASGGALAA VGAGGGPQAS SSAAGPAATS 60

TFGNLKLGRD SGKVTTVVAT PGQGPEPDLP QEVSYTDIKV IGNGSFGVVY QARLLTTGEL 120

VAIKKVLQDK RFKNRELQIM RKLDHCNIVR LRYFFYSSGE KKDEVYLNLV LDYVPETVYR 180

VARHFSKAKQ TIPIIYVKVY MYQLFRSLAY IHSQGVCHRD IKPQNLLVDP ETAILKLCDF 240

GSAKQLVRGE PNVSYICSRY YRAPELIFGA TDYTSNIDIW SAGCVLAELL LGQPIFPGDS 300

GVDQLVEIIK VLGTPTREQI REMNPNYTEF KFPQIKAHPW TKVFKTRTPP EAISLCSRLL 360

EYTPATRLSP LEACAHNFFE DLRNPNTRLP NGRELPYLFN FSPVELSIQP LLNSLLIPPH 420

ARTHAASASC AASTSSSHGE GSLSVDRTQT ALSGVAGAVN NSS 463

Nucleotide Sequence
(FASTA)

ATGATGAGCG GCCGGGCCAG GACCAGCTCC TTCGCCGACC CGCCGCCCAC CGTCACCGGC 60

TCCTCCGCCC CAGGAAAGCC CATGGTTTCG GCAGCGGCCT CCGGGGGAGC ACTAGCGGCG 120

GTGGGCGCCG GCGGCGGGCC CCAGGCCTCA AGCAGCGCAG CCGGACCCGC GGCCACCAGC 180

ACCTTCGGAA ACCTCAAACT GGGCCGAGAC AGTGGTAAGG TGACAACGGT GGTGGCAACT 240

CCGGGACAAG GACCTGAGCC CGACCTTCCC CAGGAGGTGT CCTACACCGA CATCAAGGTG 300

ATTGGAAACG GCTCGTTCGG AGTGGTGTAC CAGGCCAGGC TGCTCACCAC GGGCGAACTC 360

GTCGCCATTA AGAAGGTCCT GCAGGACAAG CGCTTCAAGA ATCGGGAGCT GCAGATCATG 420

AGAAAACTGG ATCATTGCAA CATCGTTCGG TTACGTTACT TTTTCTACTC CAGTGGCGAA 480

AAGAAAGATG AGGTTTACTT GAATCTGGTG TTGGACTACG TGCCAGAGAC AGTGTACAGA 540

GTCGCTCGAC ACTTCAGCAA GGCTAAGCAG ACCATCCCTA TCATTTATGT AAAGGTGTAT 600

ATGTACCAGT TGTTCCGTAG TTTAGCCTAC ATCCATTCCC AGGGAGTTTG TCACCGTGAT 660

ATTAAACCAC AGAATCTCCT GGTTGACCCA GAGACAGCGA TCCTTAAACT CTGTGACTTT 720

GGAAGTGCGA AGCAGTTAGT ACGAGGAGAA CCCAACGTCT CTTACATCTG TTCACGGTAT 780

TACAGGGCCC CAGAACTTAT CTTTGGAGCT ACAGACTACA CCTCCAACAT AGATATCTGG 840

TCGGCAGGGT GTGTGCTGGC AGAGCTGCTG CTGGGACAGC CCATTTTCCC TGGGGACAGC 900

GGAGTCGACC AACTTGTTGA AATCATAAAG GTGTTAGGAA CGCCGACAAG GGAACAGATC 960

CGCGAAATGA ATCCAAATTA CACAGAATTC AAATTCCCGC AGATCAAAGC GCACCCCTGG 1020

ACAAAGGTCT TTAAAACCCG GACGCCACCA GAGGCCATTT CCCTGTGCAG TCGGCTCTTG 1080

GAATACACAC CCGCCACGCG GCTCTCCCCG CTAGAAGCCT GTGCGCACAA CTTCTTCGAG 1140

GACCTGCGAA ATCCCAACAC CCGACTCCCC AACGGCAGAG AGTTACCTTA CCTCTTCAAC 1200

TTCAGCCCAG TAGAACTCTC GATTCAGCCA CTACTCAATT CTCTCCTCAT TCCTCCTCAC 1260

GCCCGAACCC ACGCTGCCTC CGCTTCCTGT GCGGCCAGTA CTTCCTCCTC ACACGGCGAA 1320

GGGAGTTTAT CAGTAGACAG GACCCAAACA GCACTCAGCG GAGTAGCAGG AGCTGTGAAC 1380

AATTCCTCCT GA 1392

Domain Profile

S: 2     eelkligsGsFgnVyqavlseesekevaiKkvlqdkklknlEleilrklkHknivrLlyf  61

         +++k+ig+GsFg+Vyqa+l ++ e  vaiKkvlqdk++kn+El+i+rkl+H+nivrL+yf

Q: 96    TDIKVIGNGSFGVVYQARLLTTGEL-VAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYF  154

         789**********************.**********************************

S: 62    fsksaekkdkvylnlvleylPetlakvlrelkdkkkkldvlevklytyQlfrglaylhsl  121

         f++s ekkd+vylnlvl+y+Pet+++v+r+++++k+++++++vk+y+yQlfr+lay+hs+

Q: 155   FYSSGEKKDEVYLNLVLDYVPETVYRVARHFSKAKQTIPIIYVKVYMYQLFRSLAYIHSQ  214

         ************************************************************

S: 122   eivHrDiKPqNllvdeetgvlKlcDfGsakrleknepnvsYivsRyYRaPELllgakeyt  181

         +++HrDiKPqNllvd+et++lKlcDfGsak+l+++epnvsYi+sRyYRaPEL++ga++yt

Q: 215   GVCHRDIKPQNLLVDPETAILKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYT  274

         ************************************************************

S: 182   tkiDvWsagcvlaEllkgkvlfkgksakdqlelivkvlGtptkedikemnvkykekkfkk  241

         ++iD+WsagcvlaEll+g+++f+g+s++dql++i+kvlGtpt+e+i+emn++y+e+kf++

Q: 275   SNIDIWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQ  334

         ************************************************************

S: 242   ikkvslakvlkkkedkeavdllkkilkyepkkRlsalellahpff  286

         ik+++++kv+k+++++ea+ l++++l+y+p++Rls+le++ah+ff

Q: 335   IKAHPWTKVFKTRTPPEAISLCSRLLEYTPATRLSPLEACAHNFF  379

         ********************************************9

Domain Sequence
(FASTA)

TDIKVIGNGS FGVVYQARLL TTGELVAIKK VLQDKRFKNR ELQIMRKLDH CNIVRLRYFF 60

YSSGEKKDEV YLNLVLDYVP ETVYRVARHF SKAKQTIPII YVKVYMYQLF RSLAYIHSQG 120

VCHRDIKPQN LLVDPETAIL KLCDFGSAKQ LVRGEPNVSY ICSRYYRAPE LIFGATDYTS 180

NIDIWSAGCV LAELLLGQPI FPGDSGVDQL VEIIKVLGTP TREQIREMNP NYTEFKFPQI 240

KAHPWTKVFK TRTPPEAISL CSRLLEYTPA TRLSPLEACA HNFF 284

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013