EKS-LAC-00302

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LAC-00302

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/IRE	451.8	8.6E-136	435	696	262

Status

Unreviewed

Ensembl Protein

ENSLACP00000023642

UniProt Accession

H3ATY0;

Protein Name

Protein Synonyms/Alias

Gene Name

ERN2

Gene Synonyms/Alias

ERN2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000011540	ENSLACP00000023642	ENSLACT00000025482
ENSLACG00000011540	ENSLACP00000013101	ENSLACT00000013197

Organism

Latimeria chalumnae

Functional Description

Protein Length

834

Protein Sequence
(FASTA)

MKQTTLSTQS SDGVCPSAPL LYIGRTEYII TMYDTKTREV RWNATYHDYS APLYNEKYDY 60

KMAHFASNGD GLLVTVDKET GEILWMHNYG SPVVGIYTWQ QDSLHRVPHL NVAMETLRYL 120

TFTSQDIRMI KWNYQFLKQQ STAKTQLLPA LYVGKFDTNF YASSSLVHEG VTIVPREISF 180

AHIEGPTTDD VTVRESGECE ITPSTDVKYP QGTIYLQKQW LLIGHHELPP VAHTTILRAF 240

PENLKRTSEA VIPTRPAGRT VFDDFLTPNI PEEQPSESDG RQRFETTKEE EMRTEVVPET 300

ETQDLIIVGI LTILIGGWIL FAVTYPRKIH QQQKLQQQQL EEKLQLLQQQ VPPSPREYSS 360

ENFSLDLIGS MDTMTQTSFK GSEGSSVPTR EGSNKSSSSQ KSLSNGLYSQ VYSMLNSENV 420

DDPDTDLFVV GKISFNPKDV LGHGAEGTLV YRGRFDDRNV AVKRILPECF TFADREVQLL 480

RESDEHPNVI RYFCTEKDKQ FSYIAIELCA ATLQEYVEEP SFSHIELDPV TLLYQTMSGL 540

AHLHSLNIVH RDLKPRNILI SLPNSHGKVR AVISDFGLCK KLPDGRHSFS LRSGIPGTEG 600

WIAPEVLGED LKENPTYAVD IFSAGCVFYY VVSQGQHPFG ASLRRQSNIL SGLYTLEQFV 660

ENIHEDVIAR DLIEQMIKSD PQQRPSARCV LKHPFFWSQE KQLQFFQDVS DRIEKEPTEG 720

PIMTALELGG RLVVRTNWRM HISVPLQTDL RKFRTYKGNS VRDLLRAMRN KKHHYHELPA 780

EVQETLGEVP EGFIQYFTSR FPHLLLHTRN VMKICLRERL FQPYYHHEDD NHRR 834

Nucleotide Sequence
(FASTA)

ATGAAGCAAA CTACATTATC TACTCAGTCA TCGGATGGTG TATGTCCATC AGCTCCTCTT 60

TTGTATATTG GGCGGACAGA ATATATAATC ACCATGTATG ACACAAAAAC TCGAGAAGTT 120

CGGTGGAATG CTACGTATCA TGATTATTCT GCACCTTTAT ATAATGAGAA GTATGATTAC 180

AAAATGGCTC ATTTTGCTTC CAATGGTGAT GGCTTATTAG TTACGGTGGA CAAGGAAACG 240

GGTGAAATTT TGTGGATGCA TAATTATGGC TCTCCTGTAG TTGGCATTTA TACGTGGCAA 300

CAAGATAGTC TACACAGAGT TCCTCACCTT AATGTTGCCA TGGAAACACT GCGTTACCTT 360

ACTTTCACCT CACAGGACAT TCGCATGATC AAGTGGAACT ATCAGTTTCT GAAACAGCAG 420

TCTACTGCCA AGACACAGTT ACTGCCAGCA TTATATGTGG GAAAGTTTGA CACTAATTTC 480

TATGCTTCTT CCTCACTTGT TCATGAGGGT GTGACTATTG TGCCAAGGGA AATTAGCTTT 540

GCCCATATTG AAGGGCCTAC AACAGATGAT GTTACAGTGA GAGAAAGTGG AGAATGTGAG 600

ATAACACCCA GCACTGATGT CAAATACCCC CAGGGTACCA TTTACCTTCA GAAGCAGTGG 660

CTACTTATAG GTCACCATGA ACTTCCTCCA GTGGCTCACA CAACTATACT AAGAGCCTTT 720

CCTGAAAATC TGAAGAGGAC TTCTGAAGCA GTCATACCCA CAAGGCCTGC TGGGAGGACA 780

GTCTTTGATG ACTTTTTGAC CCCAAATATA CCAGAAGAGC AACCAAGTGA AAGCGATGGC 840

CGACAGCGAT TTGAAACTAC CAAGGAAGAA GAGATGCGTA CTGAAGTTGT ACCTGAAACT 900

GAGACCCAGG ACTTGATCAT TGTGGGAATT CTTACCATAC TTATAGGAGG GTGGATACTT 960

TTTGCAGTCA CGTATCCAAG GAAAATTCAC CAGCAACAAA AACTACAACA GCAACAGCTG 1020

GAAGAAAAAT TGCAACTCCT CCAACAGCAG GTTCCACCTT CTCCGAGAGA ATACTCCAGT 1080

GAGAATTTCA GCTTGGACCT GATAGGATCT ATGGACACGA TGACTCAAAC ATCTTTCAAG 1140

GGGTCAGAGG GCTCTTCTGT GCCAACAAGA GAGGGCAGCA ACAAGTCCTC CTCTTCACAG 1200

AAGAGTTTGT CGAATGGATT GTACAGCCAA GTTTACTCCA TGTTGAATTC AGAAAATGTG 1260

GATGATCCCG ATACAGACTT GTTTGTAGTG GGAAAAATCT CCTTTAATCC CAAAGATGTT 1320

TTGGGTCATG GAGCAGAGGG CACGCTTGTG TACCGGGGTC GCTTTGATGA CAGAAATGTT 1380

GCAGTGAAGA GAATTCTTCC CGAATGCTTC ACTTTTGCAG ATCGTGAAGT TCAGCTTCTT 1440

CGAGAGTCCG ACGAACATCC AAATGTCATT CGGTATTTTT GCACCGAGAA AGATAAACAG 1500

TTCTCTTATA TAGCAATTGA GCTATGTGCT GCAACTCTAC AAGAGTATGT TGAAGAACCT 1560

AGCTTTAGCC ACATTGAGTT AGACCCAGTG ACACTGCTTT ACCAGACAAT GTCTGGCCTC 1620

GCTCACCTAC ATTCTCTTAA TATAGTGCAC CGTGATTTGA AACCTCGTAA CATCCTTATC 1680

TCTTTACCCA ACTCCCATGG GAAGGTGAGA GCTGTGATTT CAGACTTTGG CTTGTGTAAG 1740

AAGCTGCCTG ATGGGCGACA CAGCTTTAGT CTGCGCTCTG GCATACCTGG GACTGAAGGA 1800

TGGATCGCTC CAGAGGTTCT AGGGGAGGAC CTAAAGGAGA ATCCTACATA TGCAGTTGAC 1860

ATTTTCTCGG CAGGATGTGT ATTCTACTAT GTAGTTTCTC AAGGACAACA TCCATTTGGT 1920

GCCTCACTAA GGAGACAATC CAACATTTTA TCTGGATTAT ACACTTTAGA ACAGTTCGTG 1980

GAAAATATTC ATGAGGATGT TATAGCAAGA GACTTAATTG AACAAATGAT TAAGAGCGAC 2040

CCACAACAGC GACCCTCAGC AAGATGTGTT CTCAAGCACC CTTTTTTTTG GAGTCAAGAG 2100

AAACAGCTGC AGTTCTTTCA GGATGTAAGT GACCGTATAG AAAAGGAGCC AACTGAGGGG 2160

CCTATCATGA CTGCTTTGGA ATTGGGTGGA AGGCTGGTTG TGAGGACTAA CTGGAGAATG 2220

CACATCTCAG TACCTCTCCA GACAGACCTG AGAAAATTTA GAACATACAA AGGAAATTCT 2280

GTTCGAGACC TACTGAGAGC CATGAGGAAT AAGAAACACC ACTACCATGA GCTACCAGCA 2340

GAAGTGCAGG AAACGCTGGG AGAGGTACCT GAAGGCTTTA TACAGTACTT TACATCTCGG 2400

TTTCCACACT TACTGCTTCA TACTCGGAAC GTCATGAAAA TCTGTTTGAG AGAGAGACTT 2460

TTTCAGCCAT ATTATCACCA TGAAGATGAC AATCACAGAA GATAA 2505

Domain Profile

S: 1     fspkdvlGkGaeGtvvfrGsfegrevavkrllsefvdlakrevkllresdehpnviryfc  60

         f+pkdvlG+GaeGt+v+rG f++r+vavkr+l+e++++a+rev+llresdehpnviryfc

Q: 435   FNPKDVLGHGAEGTLVYRGRFDDRNVAVKRILPECFTFADREVQLLRESDEHPNVIRYFC  494

         799*********************************************************

S: 61    tekdrqfryialelcaaslqdyvedkdlelqkelepisllkqiasGlahlhslkivhrdl  120

         tekd+qf yia+elcaa+lq+yve+++++ + el+p++ll q++sGlahlhsl+ivhrdl

Q: 495   TEKDKQFSYIAIELCAATLQEYVEEPSFS-HIELDPVTLLYQTMSGLAHLHSLNIVHRDL  553

         *****************************.******************************

S: 121   kpqnilislpdakgklrvlisdfGlckkldvGkssfsrrsgvsGteGwiapelleeltke  180

         kp+nilislp+++gk+r++isdfGlckkl+ G++sfs rsg++GteGwiape+l e+ ke

Q: 554   KPRNILISLPNSHGKVRAVISDFGLCKKLPDGRHSFSLRSGIPGTEGWIAPEVLGEDLKE  613

         ************************************************************

S: 181   rltsavdifslGcvfyyvlskGkhpfGdslkrqanilsgelsldklkeekdeeviaedli  240

         ++t+avdifs+Gcvfyyv+s+G+hpfG sl+rq+nilsg ++l+++ e+ +e+via+dli

Q: 614   NPTYAVDIFSAGCVFYYVVSQGQHPFGASLRRQSNILSGLYTLEQFVENIHEDVIARDLI  673

         ************************************************************

S: 241   skmidkdplkrpsakkvlkhplf  263

         ++mi+ dp++rpsa++vlkhp+f

Q: 674   EQMIKSDPQQRPSARCVLKHPFF  696

         **********************9

Domain Sequence
(FASTA)

FNPKDVLGHG AEGTLVYRGR FDDRNVAVKR ILPECFTFAD REVQLLRESD EHPNVIRYFC 60

TEKDKQFSYI AIELCAATLQ EYVEEPSFSH IELDPVTLLY QTMSGLAHLH SLNIVHRDLK 120

PRNILISLPN SHGKVRAVIS DFGLCKKLPD GRHSFSLRSG IPGTEGWIAP EVLGEDLKEN 180

PTYAVDIFSA GCVFYYVVSQ GQHPFGASLR RQSNILSGLY TLEQFVENIH EDVIARDLIE 240

QMIKSDPQQR PSARCVLKHP FF 262

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ciona intestinalis"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Microcebus murinus"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0016891	; F:endoribonuclease activity, producing 5'-phosphomonoesters
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006397	; P:mRNA processing

KEGG

InterPros

IPR010513	; KEN_RNase_activator.
IPR011009	; Kinase-like_dom.
IPR018391	; PQQ_beta_propeller_repeat.
IPR000719	; Prot_kinase_cat_dom.
IPR006567	; PUG-dom.
IPR011047	; Quinonprotein_ADH-like.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF06479	; Ribonuc_2-5A; 1.

SMARTs

SM00564	; PQQ; 5.
SM00580	; PUG; 1.

Prosites

PS51392	; KEN; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013