EKS-LAC-00490

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LAC-00490

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMK2	584.3	3.1E-176	73	331	259

Status

Unreviewed

Ensembl Protein

ENSLACP00000013490

UniProt Accession

H3AV19;

Protein Name

Protein Synonyms/Alias

Gene Name

CAMK2G

Gene Synonyms/Alias

CAMK2G;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000011877	ENSLACP00000013491	ENSLACT00000013587
ENSLACG00000011877	ENSLACP00000013490	ENSLACT00000013586

Organism

Latimeria chalumnae

Functional Description

Protein Length

577

Protein Sequence
(FASTA)

MCVCVSLSRA LSLSLSLSLS LSVSPPSSDF APQARAKAAV SRFPTFPPPR CKNSSTSPNM 60

ATTATCTRFT EEYQLYEELG KGAFSVVRRC VKKSTGQEYA AKIINTKKLS ARDHQKLERE 120

ARICRLLKHP NIVRLHDSIS EEGFHYLVFD LVTGGELFED IVAREYYSEA DASQCIHQIL 180

ESVNHIHQHD IVHRDLKPEN LLLASKCKGA AVKLADFGLA IEVQGEQQAW FGFAGTPGYL 240

SPEVLRKDPY GKPVDIWACG VILYILLVGY PPFWDEDQHK LYQQIKAGAY DFPSPEWDTV 300

TPEAKNLINQ MLTINPAKRI TADQALKHPW VCQRSTVASM MHRQETVECL RKFNARRKLK 360

GAILTTMLVS RNFSVAKSLL NKKTDGVKPQ TNNNKNNVVS SPKENIPSQT PMEPQTTVVH 420

NPADGIKEST ESCNTTTEDE DMKARKQDII KITEQLIEAI NNGDFEAYTK ICDPGLTSFE 480

PEALGNLVEG MDFHKFYFEN LLSKNSKPIH TTILNPHVHL IGEDAACIAY IRLTQYIDSQ 540

GRPRTVQSEE TRVWHRRDGK WLNVHFHCSG APAAPLQ 577

Nucleotide Sequence
(FASTA)

ATGTGTGTGT GTGTCTCTCT CTCTCGCGCG CTCTCTCTCT CTCTCTCTCT CTCTCTCTCT 60

CTGTCAGTTT CCCCTCCCAG CAGTGACTTT GCACCGCAAG CCAGAGCGAA AGCTGCAGTT 120

TCACGATTTC CAACCTTCCC CCCTCCCCGA TGCAAGAACA GCTCCACCAG CCCTAACATG 180

GCTACTACCG CAACGTGTAC GCGATTCACA GAGGAATACC AGCTCTACGA GGAGCTCGGA 240

AAGGGTGCCT TCTCCGTTGT CCGCAGATGC GTAAAAAAAT CCACTGGGCA GGAGTATGCT 300

GCTAAAATTA TTAACACCAA AAAGCTCTCA GCCAGAGATC ACCAAAAGTT GGAGCGTGAA 360

GCTCGAATCT GTCGGCTGTT AAAGCACCCA AACATTGTGC GTCTCCATGA CAGCATTTCA 420

GAAGAAGGAT TCCATTACCT TGTTTTTGAC CTGGTTACTG GAGGGGAATT GTTTGAAGAC 480

ATAGTTGCGA GAGAATACTA CAGTGAAGCT GATGCAAGCC AGTGTATCCA TCAGATACTG 540

GAAAGCGTCA ACCACATCCA CCAGCATGAC ATTGTCCATA GAGACCTAAA GCCTGAAAAC 600

TTGTTACTGG CAAGCAAGTG CAAAGGAGCA GCTGTGAAAC TCGCTGATTT TGGACTGGCT 660

ATTGAAGTGC AAGGAGAACA GCAGGCATGG TTTGGTTTTG CTGGTACTCC AGGTTACCTT 720

TCCCCCGAGG TCCTAAGAAA AGACCCTTAT GGAAAACCAG TTGATATCTG GGCATGTGGT 780

GTTATTCTGT ACATATTGTT AGTTGGGTAC CCACCCTTCT GGGATGAAGA TCAACACAAA 840

CTTTATCAAC AAATAAAGGC TGGTGCTTAT GATTTCCCAT CTCCAGAGTG GGACACAGTT 900

ACTCCTGAAG CCAAAAACCT GATCAATCAG ATGTTAACCA TCAACCCTGC TAAAAGAATC 960

ACAGCAGATC AGGCTCTCAA ACACCCATGG GTCTGCCAAC GGTCCACTGT GGCCTCCATG 1020

ATGCATCGCC AGGAGACTGT GGAATGTTTG AGAAAGTTCA ATGCCAGAAG AAAGCTGAAG 1080

GGTGCAATCC TTACTACAAT GTTGGTTTCA AGAAATTTTT CAGTAGCCAA GAGTTTACTT 1140

AACAAGAAAA CAGATGGAGT GAAGCCACAG ACCAACAACA ACAAAAACAA CGTAGTAAGC 1200

AGTCCCAAAG AAAACATTCC GTCACAAACT CCGATGGAGC CCCAGACAAC TGTAGTCCAC 1260

AACCCAGCAG ATGGCATCAA GGAATCAACT GAGAGCTGCA ACACGACAAC TGAGGATGAG 1320

GACATGAAAG CACGCAAACA AGACATTATC AAGATAACTG AGCAGCTAAT CGAAGCAATT 1380

AACAATGGAG ACTTTGAGGC TTACACGAAA ATCTGTGACC CTGGCCTGAC TTCATTTGAA 1440

CCTGAAGCAC TTGGAAACCT AGTGGAGGGG ATGGACTTTC ACAAGTTTTA CTTTGAGAAC 1500

TTGTTGTCCA AGAACAGCAA GCCAATCCAT ACGACCATCC TCAATCCTCA CGTCCATCTC 1560

ATTGGAGAGG ATGCTGCCTG TATTGCCTAT ATCCGTCTGA CACAGTACAT TGACAGCCAG 1620

GGGCGGCCCA GGACTGTGCA GTCTGAAGAG ACCCGCGTCT GGCACCGCCG TGATGGCAAA 1680

TGGCTAAATG TGCACTTCCA CTGTTCGGGA GCACCTGCTG CACCACTCCA GTGA 1734

Domain Profile

S: 1     yqlfeelgkgafsvvrrcvkvttgqeyaakiintkklsardhqklerearicrllkhpni  60

         yql+eelgkgafsvvrrcvk++tgqeyaakiintkklsardhqklerearicrllkhpni

Q: 73    YQLYEELGKGAFSVVRRCVKKSTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI  132

         9***********************************************************

S: 61    vrlhdsiseegfhylvfdlvtggelfedivareyyseadashciqqilesvlhihqngvv  120

         vrlhdsiseegfhylvfdlvtggelfedivareyyseadas+ci+qilesv+hihq+++v

Q: 133   VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASQCIHQILESVNHIHQHDIV  192

         ************************************************************

S: 121   hrdlkpenlllaskakgaavkladfglaievqgdqqawfgfagtpgylspevlrkdpygk  180

         hrdlkpenlllask+kgaavkladfglaievqg+qqawfgfagtpgylspevlrkdpygk

Q: 193   HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGK  252

         ************************************************************

S: 181   pvdlwacgvilyillvgyppfwdedqhrlyqqikagaydfpspewdtvtpeakdlinkml  240

         pvd+wacgvilyillvgyppfwdedqh+lyqqikagaydfpspewdtvtpeak+lin+ml

Q: 253   PVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML  312

         ************************************************************

S: 241   tinpakritadealkhpwi  259

         tinpakritad+alkhpw+

Q: 313   TINPAKRITADQALKHPWV  331

         ******************8

Domain Sequence
(FASTA)

YQLYEELGKG AFSVVRRCVK KSTGQEYAAK IINTKKLSAR DHQKLEREAR ICRLLKHPNI 60

VRLHDSISEE GFHYLVFDLV TGGELFEDIV AREYYSEADA SQCIHQILES VNHIHQHDIV 120

HRDLKPENLL LASKCKGAAV KLADFGLAIE VQGEQQAWFG FAGTPGYLSP EVLRKDPYGK 180

PVDIWACGVI LYILLVGYPP FWDEDQHKLY QQIKAGAYDF PSPEWDTVTP EAKNLINQML 240

TINPAKRITA DQALKHPWV 259

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004683	; F:calmodulin-dependent protein kinase activity

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR013543	; Ca/CaM-dep_prot_kinase-assoc.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF08332	; CaMKII_AD; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013