EKS-LAC-00071

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LAC-00071

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	345.1	3.3E-103	65	349	285

Status

Unreviewed

Ensembl Protein

ENSLACP00000013862

UniProt Accession

H3AW41;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK15

Gene Synonyms/Alias

CDK15;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000012204	ENSLACP00000013862	ENSLACT00000013959

Organism

Latimeria chalumnae

Functional Description

Protein Length

397

Protein Sequence
(FASTA)

SFQLTDITEA PFPVDAVQPH WFHTLQVRKL RVHRSRSNSD PLGGKSYAQG LQWRSGLRFG 60

TASSYLNLEK LGEGSYATVY KGISRINGHL VALKVIKMKA EEGVPFTAIR EASLLKGLKH 120

ANIVLLHDII QTRETLTFVF EYVQTDLGQY MIQHPGGLHP HNVKLFLFQL LRGLAYIHHQ 180

QILHRDLKPQ NLLISYLGEL KLADFGLARA KSIPSHTYSS EVVTLWYRPP DVLLGATDYS 240

TALDIWGAGC IFIEMLQGSP AFPGISDVTE QLEKIWTVLG IPTEETWPGV TELPNYKTEW 300

FLPCKPQRLR TIWKRLGEVP KAEDMTSKLL QCFPRDRLSA DSALHHEYFS DIPSQLFQLL 360

DAASIFQVPG VRLETEVRDI FNPFRKDRSA AGLNKCW 397

Nucleotide Sequence
(FASTA)

TCTTTTCAGC TGACAGACAT AACAGAAGCT CCTTTTCCTG TGGATGCTGT GCAGCCTCAT 60

TGGTTCCACA CGCTTCAGGT TCGAAAGTTA AGGGTCCACA GGTCAAGAAG TAATAGTGAC 120

CCTTTAGGAG GAAAAAGCTA TGCACAAGGT TTACAGTGGA GAAGTGGTCT TCGATTTGGA 180

ACTGCATCTT CCTACCTAAA CCTGGAGAAG CTGGGAGAAG GATCCTATGC CACAGTCTAT 240

AAGGGGATAA GCAGAATAAA TGGTCACCTG GTTGCTTTAA AAGTCATCAA GATGAAGGCA 300

GAGGAAGGGG TGCCTTTCAC AGCTATCAGG GAAGCTTCTC TTCTAAAGGG TTTGAAACAT 360

GCCAACATTG TCCTTCTACA TGACATTATT CAGACACGGG AGACATTGAC ATTTGTCTTT 420

GAGTATGTGC AAACAGACTT GGGGCAGTAC ATGATTCAAC ATCCAGGAGG GCTCCATCCA 480

CACAACGTTA AGCTTTTCTT GTTCCAGCTA TTGAGAGGTT TAGCCTACAT CCACCACCAG 540

CAGATCCTTC ACCGGGATTT AAAACCACAG AATTTGCTCA TCAGCTACCT TGGGGAACTC 600

AAACTGGCTG ACTTTGGTTT AGCCCGTGCC AAGTCCATTC CCAGTCACAC ATACTCCTCA 660

GAGGTGGTGA CCCTCTGGTA CCGACCCCCT GATGTACTTC TCGGAGCCAC AGACTACTCA 720

ACTGCACTAG ATATTTGGGG TGCTGGGTGC ATCTTTATTG AAATGCTGCA GGGATCTCCT 780

GCATTCCCTG GAATCTCTGA TGTCACTGAG CAGCTAGAGA AAATCTGGAC AGTTTTAGGG 840

ATTCCAACAG AAGAGACATG GCCAGGGGTG ACAGAGCTAC CGAACTACAA AACAGAGTGG 900

TTTCTGCCCT GTAAGCCACA GAGGCTCAGA ACTATTTGGA AGAGACTAGG AGAAGTGCCA 960

AAGGCAGAAG ACATGACCTC GAAGCTGCTG CAGTGCTTTC CTCGGGACCG CCTTTCCGCA 1020

GATAGCGCTC TCCACCATGA ATATTTCAGC GATATCCCCT CTCAGCTGTT CCAGCTACTT 1080

GATGCTGCCT CCATTTTCCA GGTGCCTGGA GTAAGGTTGG AGACAGAAGT CCGAGACATC 1140

TTCAACCCAT TTAGAAAAGA CAGAAGTGCA GCAGGGCTCA ACAAGTGCTG GTGA 1194

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y +lek+geG+y++vyk+ ++ +g++vAlK i+++ e egvp+ta+rE sllk lkh+ni

Q: 65    YLNLEKLGEGSYATVYKGISRINGHLVALKVIKMKAE-EGVPFTAIREASLLKGLKHANI  123

         6789******************************999.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v L+++++ ++++l++vfe++++dL +++ +++  +l++++vk +l+qll+glay+H+++

Q: 124   VLLHDIIQ-TRETLTFVFEYVQTDLGQYMIQHPG-GLHPHNVKLFLFQLLRGLAYIHHQQ  181

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         ilHRDlKpqNlLis  g+lklaDfGlara s p++ty++evvTlwYr+P++Llga++Yst

Q: 182   ILHRDLKPQNLLISYLGELKLADFGLARAKSIPSHTYSSEVVTLWYRPPDVLLGATDYST  241

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkse.idqlerifkllgtpsekvwpevsklpeyk.ksf  238

         a+DiW++gci+ e+l+ +p f+g s+ ++qle+i+++lg p+e++wp+v++lp+yk + f

Q: 242   ALDIWGAGCIFIEMLQGSPAFPGISDvTEQLEKIWTVLGIPTEETWPGVTELPNYKtEWF  301

         ***********************998689***************************8899

S: 239   pkkkkkklkekvkklk..ekaldllekllaldpkkRisakealqhkyf  284

          + k+++l++ +k+l    ka d+ +kll++ p++R+sa++al+h+yf

Q: 302   LPCKPQRLRTIWKRLGevPKAEDMTSKLLQCFPRDRLSADSALHHEYF  349

         99************9955579**************************9

Domain Sequence
(FASTA)

YLNLEKLGEG SYATVYKGIS RINGHLVALK VIKMKAEEGV PFTAIREASL LKGLKHANIV 60

LLHDIIQTRE TLTFVFEYVQ TDLGQYMIQH PGGLHPHNVK LFLFQLLRGL AYIHHQQILH 120

RDLKPQNLLI SYLGELKLAD FGLARAKSIP SHTYSSEVVT LWYRPPDVLL GATDYSTALD 180

IWGAGCIFIE MLQGSPAFPG ISDVTEQLEK IWTVLGIPTE ETWPGVTELP NYKTEWFLPC 240

KPQRLRTIWK RLGEVPKAED MTSKLLQCFP RDRLSADSAL HHEYF 285

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013