EKS-LAC-00331

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LAC-00331

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	321.8	3.7E-96	28	281	254

Status

Unreviewed

Ensembl Protein

ENSLACP00000015051

UniProt Accession

H3AZI0;

Protein Name

Protein Synonyms/Alias

Gene Name

TAOK1

Gene Synonyms/Alias

TAOK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000013244	ENSLACP00000015051	ENSLACT00000015157

Organism

Latimeria chalumnae

Functional Description

Protein Length

1003

Protein Sequence
(FASTA)

MPPTGRAGSL KDPEVAELFF KEDPEKLFSD LREIGHGSFG AVYFARDVRT NEVVAIKKMS 60

YSGKQSNEKW QDIIKEVKFL QRIKHPNSIE YKGCYLREHT AWLVMEYCLG SASDLLEVHK 120

KPLQEVEIAA ITHGALQGLA YLHSHNMIHR DIKAGNILLT EPGQVKLADF GSASIASPAN 180

SFVGTPYWMA PEVILAMDEG QYDGKVDVWS LGITCIELAE RKPPLFNMNA MSALYHIAQN 240

ESPTLQSNEW SDYFRNFVDS CLQKIPQDRP TSEELLKHAF VLRERPETVL IDLIQRTKDA 300

VRELDNLQYR KMKKILFQEA HNGPVVEPPD EEEVGEENEE RCGQVSCFIP GDNPTPSYHL 360

CAPVKNSALH CPLNAIEDMA IILCFYSSYT VVVSNGQIVY LFRDEENYRE EAEMRARASE 420

PQSPPQVSRH KSHYRNREHF ATIRTASLVT RQIQEHEQDS ELREQMSGYK RMRRQHQKQL 480

MALENKLKAE MDEHRLKLDK ELETQRNNFA AEMEKLVKKH QAIMEKEAKV MTNEEKKFQQ 540

HIQGQQKKEL NSFLESQKRE YKLRKEQLKE ELNENQSTPK KEKQEWLSKQ KENFQHFQAE 600

EEANLLRRQR QYLELECRRF KRRMLLGRHN LEQDLLREEL NKRQTQKDLE HAMLLRQHES 660

MQELEFRHLN TIQKMRCELI RLQHQTELNN QQEYNKRRER ELRRKHVMEV RQQPKSLKSK 720

ELQIKKQFQD TCKIQTRQYK ALRNHLLETT PKSEHKAVLK RLKEEQTRKL AILAEQYDHS 780

INEMLSTQAL RLDEAQEAEC QVLKMQLLQE LELLNAYQSK IKMQAEAQHE RELRELEQRV 840

SLRRALLEQK IEEEMLALQN ERTERIRSLL ERQAREIEAF DSESMRLGFS NMVLSNLSPE 900

AFSHSYPGAS SWSHNPAGAP GSHWGHPMAG PPQAWGHPMQ GGPQPWGHPS GPMAAVPRGS 960

AMGVRNSPQA LRRTASGGRP EQGMSRSTSV TSQISNGSHM SYT 1003

Nucleotide Sequence
(FASTA)

ATGCCGCCAA CCGGCCGAGC TGGAAGTCTA AAGGACCCGG AGGTAGCAGA GCTCTTCTTT 60

AAGGAAGATC CCGAGAAGCT TTTCTCAGAC CTTCGTGAGA TCGGCCATGG CAGCTTTGGA 120

GCTGTGTATT TTGCACGTGA TGTGCGCACC AACGAGGTGG TGGCCATCAA GAAAATGTCC 180

TACAGTGGGA AACAGTCTAA TGAGAAATGG CAGGATATTA TCAAAGAAGT GAAATTTCTG 240

CAAAGGATAA AACACCCTAA TAGTATTGAA TACAAAGGCT GCTATCTGCG GGAACACACA 300

GCATGGCTTG TTATGGAATA CTGTTTAGGA TCAGCGTCAG ACCTGCTGGA AGTTCATAAA 360

AAACCTCTTC AGGAAGTAGA GATAGCAGCT ATTACCCATG GTGCTCTGCA GGGATTAGCA 420

TATTTGCATT CTCACAACAT GATACATAGA GATATTAAGG CAGGCAACAT CTTGCTGACA 480

GAGCCAGGAC AGGTGAAGCT AGCTGATTTT GGATCTGCTT CCATAGCATC TCCTGCTAAT 540

TCCTTTGTGG GGACACCATA TTGGATGGCC CCTGAAGTAA TTCTAGCCAT GGATGAAGGG 600

CAGTACGATG GAAAAGTAGA TGTTTGGTCA CTAGGAATTA CTTGTATTGA ATTAGCGGAG 660

AGGAAACCCC CTTTGTTTAA TATGAATGCA ATGAGTGCCT TATATCACAT AGCGCAGAAT 720

GAGTCTCCCA CACTACAGTC TAATGAATGG TCTGACTATT TTCGAAACTT TGTAGACTCT 780

TGCCTTCAGA AAATTCCCCA GGACAGACCC ACGTCAGAGG AACTGTTGAA GCATGCATTT 840

GTCCTTCGAG AGCGCCCAGA AACAGTGTTA ATAGATCTGA TCCAGAGAAC CAAGGATGCG 900

GTAAGAGAAC TGGACAACCT ACAGTATCGC AAGATGAAGA AGATCCTGTT CCAGGAGGCT 960

CACAATGGGC CAGTGGTGGA ACCGCCAGAT GAGGAGGAGG TAGGGGAGGA AAATGAAGAA 1020

AGGTGTGGGC AGGTCTCGTG CTTCATCCCT GGAGATAACC CCACCCCATC TTACCATTTG 1080

TGTGCACCTG TGAAGAACAG TGCTCTACAC TGCCCACTAA ATGCAATAGA AGATATGGCA 1140

ATTATTCTGT GTTTTTATAG TAGTTATACT GTAGTAGTTA GCAATGGGCA AATCGTGTAT 1200

CTTTTTAGGG ATGAAGAAAA CTACAGAGAG GAGGCAGAGA TGAGGGCAAG AGCCTCTGAA 1260

CCCCAGTCAC CACCCCAGGT CTCTCGCCAC AAGTCACATT ATAGGAACCG GGAGCATTTT 1320

GCCACCATTC GAACAGCATC CCTGGTGACC CGGCAGATCC AAGAGCACGA ACAAGACTCA 1380

GAGCTACGGG AGCAGATGTC CGGGTACAAG CGCATGAGAC GGCAGCACCA GAAGCAGCTG 1440

ATGGCCCTGG AGAACAAGCT GAAGGCTGAG ATGGATGAGC ACCGCCTCAA GCTGGATAAA 1500

GAGCTGGAAA CTCAGCGCAA CAACTTTGCA GCAGAGATGG AGAAATTGGT CAAAAAGCAT 1560

CAGGCCATCA TGGAGAAGGA GGCTAAAGTA ATGACAAACG AAGAGAAGAA ATTCCAGCAG 1620

CATATTCAGG GGCAGCAGAA GAAAGAGCTG AACAGCTTCC TGGAATCCCA GAAGAGAGAG 1680

TACAAACTGC GGAAGGAGCA GCTCAAGGAG GAGCTGAATG AGAATCAGAG CACCCCAAAG 1740

AAAGAGAAGC AGGAATGGCT GTCCAAGCAA AAAGAAAACT TCCAGCACTT CCAGGCAGAA 1800

GAAGAGGCCA ACTTGTTGCG ACGGCAGCGC CAGTACTTGG AGCTGGAATG CCGTCGCTTC 1860

AAAAGGAGGA TGCTTCTCGG GCGTCACAAC CTGGAGCAGG ACTTGCTTCG AGAGGAGCTG 1920

AACAAGCGCC AGACCCAGAA GGACCTGGAG CACGCCATGT TGCTGCGGCA GCATGAGTCC 1980

ATGCAGGAGC TGGAGTTCCG CCACCTCAAC ACCATCCAGA AAATGCGATG CGAGCTGATC 2040

CGCCTGCAGC ACCAGACAGA GCTCAACAAC CAGCAGGAGT ACAACAAGAG GAGAGAGCGG 2100

GAGCTGAGGC GCAAGCACGT CATGGAGGTC CGACAGCAGC CCAAGAGTCT CAAGTCTAAA 2160

GAGCTGCAGA TTAAGAAGCA GTTCCAGGAT ACGTGCAAGA TCCAAACCCG GCAGTACAAG 2220

GCACTGCGGA ACCACCTGCT GGAGACCACG CCGAAGAGTG AGCACAAGGC AGTGCTAAAG 2280

AGACTCAAGG AGGAACAGAC GAGGAAACTG GCCATCCTGG CTGAGCAGTA TGACCACAGC 2340

ATCAACGAGA TGCTCTCCAC GCAAGCACTG CGTTTAGATG AAGCACAGGA GGCGGAGTGC 2400

CAGGTGTTGA AGATGCAGCT GCTGCAGGAA CTGGAGCTGC TAAACGCGTA CCAGAGCAAG 2460

ATCAAAATGC AGGCCGAAGC ACAGCATGAA CGGGAGCTCC GGGAGCTGGA GCAGAGAGTG 2520

TCTCTCCGCA GGGCTCTCCT CGAGCAGAAG ATTGAGGAAG AAATGCTGGC ACTACAGAAT 2580

GAGCGCACTG AGCGGATACG AAGCTTGTTG GAGCGTCAGG CCAGAGAGAT TGAGGCGTTC 2640

GACTCAGAGA GCATGAGGCT TGGGTTCAGT AACATGGTTC TCTCCAACCT CTCCCCGGAG 2700

GCATTCAGCC ACAGTTACCC TGGGGCTTCC AGCTGGTCCC ACAATCCTGC AGGGGCCCCT 2760

GGATCTCACT GGGGTCACCC CATGGCTGGT CCGCCACAAG CCTGGGGCCA CCCCATGCAA 2820

GGAGGTCCCC AACCCTGGGG TCACCCTTCT GGACCTATGG CTGCAGTACC ACGAGGCAGT 2880

GCCATGGGGG TCCGCAATAG TCCTCAAGCA TTAAGACGGA CGGCTTCGGG GGGACGACCC 2940

GAGCAAGGCA TGAGCAGGAG CACAAGCGTC ACTTCTCAAA TATCTAATGG TTCACACATG 3000

TCTTATACAT AA 3012

Domain Profile

S: 1     yelleeigkGalgkvylarekktgelvaikkinlekq...ekleelqkeisvlkklkhpn  57

         ++ l+eig+G++g+vy ar+++t+e+vaikk++++ +   ek+++++ke+++l+++khpn

Q: 28    FSDLREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKqsnEKWQDIIKEVKFLQRIKHPN  87

         67899*****************************988899********************

S: 58    iveylesflkeeelwlvmeylagGslsdlvkeelkselkEeqiayilrevlkaLeylHsk  117

          +ey +++l+e++ wlvmey+  Gs+sdl++ ++k++l+E +ia+i++++l++L+ylHs+

Q: 88    SIEYKGCYLREHTAWLVMEYCL-GSASDLLE-VHKKPLQEVEIAAITHGALQGLAYLHSH  145

         *********************7.********.****************************

S: 118   kviHrdikakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaqe.ekg  176

         ++iHrdika+niLlte g+VkL+dfg+a+  +      +++vgtpywmAPEvi ++ e +

Q: 146   NMIHRDIKAGNILLTEPGQVKLADFGSASIASP----ANSFVGTPYWMAPEVILAMdEGQ  201

         **************************9988887....69**************9887999

S: 177   YdekaDiwslGItaielaegepPfkdleplkallkilkneppklkskkkfskefkefvek  236

         Yd k+D+wslGIt+ielae++pP++++++++al++i++ne+p+l+s+ ++s+ f++fv++

Q: 202   YDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPTLQSN-EWSDYFRNFVDS  260

         ********************************************888.************

S: 237   clqknpekRpsasellkhkFl  257

         clqk p++Rp+++ellkh+F+

Q: 261   CLQKIPQDRPTSEELLKHAFV  281

         ********************7

Domain Sequence
(FASTA)

FSDLREIGHG SFGAVYFARD VRTNEVVAIK KMSYSGKQSN EKWQDIIKEV KFLQRIKHPN 60

SIEYKGCYLR EHTAWLVMEY CLGSASDLLE VHKKPLQEVE IAAITHGALQ GLAYLHSHNM 120

IHRDIKAGNI LLTEPGQVKL ADFGSASIAS PANSFVGTPY WMAPEVILAM DEGQYDGKVD 180

VWSLGITCIE LAERKPPLFN MNAMSALYHI AQNESPTLQS NEWSDYFRNF VDSCLQKIPQ 240

DRPTSEELLK HAFV 254

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013