EKS-LAC-00251

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LAC-00251

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	387.2	3.4E-116	56	307	252

Status

Unreviewed

Ensembl Protein

ENSLACP00000016761

UniProt Accession

H3B4E0;

Protein Name

Protein Synonyms/Alias

Gene Name

MARK4

Gene Synonyms/Alias

MARK4;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000014767	ENSLACP00000016761	ENSLACT00000016879

Organism

Latimeria chalumnae

Functional Description

Protein Length

748

Protein Sequence
(FASTA)

KMAATPLPPV VLKPTHSTLM GSRSEKGSTW SSRSLGARCR NSIASCTDEQ PHIGNYRLLK 60

TIGKGNFAKV KLARHILTGR EVAIKIIDKT QLNPTSLQKL FREVRIMKGL NHPNIVKLFE 120

VIETEKTLYL VMEYASGGEV FDYLVSHGRM KEKEARSKFR QIVSAVHYCH QKNIVHRDLK 180

AENLLLDADA NIKIADFGFS NEFTLGSKLD TFCGSPPYAA PELFQGKKYD GPEVDIWSLG 240

VILYTLVSGS LPFDGQNLKE LRERVLRGKY RVPFYMSTDC ENILRRFLVL NPSKRCTLEQ 300

IMKDKWINIG YDGDELKPYL EPEEDLGDIK RIGFTIVPPH PQPKIESPHA HPQVECIVCA 360

FFILDRRSLG LEGSDSRSGS SLSLARVRAS NDVPNGTSKS SSYSKSQRAS SSYHRQRRHS 420

DFCGPSGVSS HPKRSPTSTG EGDLKEERLP SRKASCSMVS SSRVLPPSSP MVSSANNPNK 480

SEIPDRRKDT AGTTNNIPTS VMTRRNTYVC TDRSSTDRHS LLQNGKDNSS ISNRVPPASP 540

STHSIAAASS SDRTRLSRGS NIRSTFHGGQ VRDRRGTSHN GPPTSPTLSH DATPLPQSRS 600

RATSNLFSKL TSKLTRRRKP WERERDREME GGERNREREQ RDPEKKETEP RLLRLTWNVK 660

ITSCKDPEDM MAAIRRTADA NSCQHRQTEP FLLSCSHGRD NTDQYSQFEV EVCRLQRLGV 720

NGVRFRRVSG TFLAFRNIAT KISNELQL 748

Nucleotide Sequence
(FASTA)

AAGATGGCTG CTACCCCCCT TCCCCCCGTT GTTTTAAAAC CCACTCATTC CACATTAATG 60

GGGAGCCGGT CGGAGAAAGG TTCCACCTGG TCGAGTCGTT CCCTCGGAGC GCGGTGCCGC 120

AACTCCATCG CCTCCTGCAC GGACGAGCAG CCCCACATCG GAAACTATCG CCTGCTGAAG 180

ACCATCGGCA AGGGGAACTT TGCCAAAGTA AAACTAGCCC GGCATATCCT CACTGGGAGA 240

GAGGTTGCCA TAAAGATAAT AGATAAAACC CAGCTAAATC CAACAAGTCT TCAAAAGCTT 300

TTTCGGGAAG TGAGAATAAT GAAAGGCTTA AACCACCCAA ACATCGTGAA ATTGTTTGAA 360

GTGATTGAGA CAGAGAAAAC CCTCTACCTG GTGATGGAAT ATGCCAGTGG TGGTGAGGTG 420

TTTGACTACC TCGTTTCACA TGGACGGATG AAGGAGAAAG AAGCTCGGTC TAAATTCAGA 480

CAGATTGTGT CTGCCGTTCA TTATTGTCAT CAGAAGAATA TTGTGCACAG GGACCTCAAG 540

GCCGAAAACC TCCTGCTTGA CGCTGATGCC AATATTAAAA TAGCGGACTT TGGCTTCAGC 600

AATGAGTTCA CGCTGGGGTC CAAGTTAGAT ACGTTTTGCG GCAGCCCACC CTATGCAGCT 660

CCCGAACTCT TTCAGGGGAA GAAGTACGAT GGTCCGGAGG TGGACATCTG GAGCTTGGGG 720

GTCATCCTCT ACACCTTGGT CAGTGGGTCG CTGCCTTTTG ATGGACAGAA CCTGAAGGAG 780

CTGAGAGAGA GGGTCCTCCG TGGGAAATAC CGAGTCCCCT TTTACATGTC GACGGATTGT 840

GAGAATATCC TCCGGCGGTT TCTGGTGTTG AACCCCTCCA AGCGTTGCAC CTTGGAACAA 900

ATCATGAAGG ACAAGTGGAT TAATATTGGT TACGATGGGG ATGAGCTCAA GCCGTATTTG 960

GAGCCAGAAG AAGACTTGGG AGACATTAAA CGAATTGGTT TTACCATTGT CCCCCCCCAC 1020

CCTCAGCCGA AAATAGAATC CCCCCACGCC CACCCCCAGG TTGAGTGCAT TGTCTGTGCC 1080

TTTTTTATTC TTGACAGGAG GTCGCTGGGA CTGGAGGGGA GTGATTCACG TTCCGGCAGT 1140

AGCCTGTCCC TAGCCCGAGT TCGAGCCTCG AACGACGTCC CCAACGGAAC AAGCAAGTCC 1200

TCCTCGTACA GCAAGAGCCA GAGGGCCTCT TCCTCTTACC ACAGGCAGAG GAGACACAGT 1260

GACTTCTGCG GCCCATCTGG GGTGTCGTCC CACCCAAAGC GGAGCCCCAC CAGCACGGGG 1320

GAGGGGGACC TGAAGGAGGA GCGGCTGCCG TCCCGCAAAG CCAGCTGCAG CATGGTCAGC 1380

AGTAGTCGAG TGCTCCCCCC ATCCAGCCCC ATGGTCAGCA GTGCCAATAA TCCAAACAAG 1440

TCCGAGATCC CAGACCGCAG GAAAGATACA GCTGGCACCA CGAACAATAT CCCCACCAGT 1500

GTAATGACCA GAAGGAACAC GTATGTGTGT ACGGACCGAT CGAGCACAGA CAGGCACTCC 1560

CTACTTCAGA ATGGCAAAGA CAACAGCTCC ATCTCGAACC GAGTGCCTCC AGCTTCCCCA 1620

TCTACACACA GCATCGCCGC CGCCTCCTCT TCGGACCGCA CCCGCCTCTC CCGTGGGTCC 1680

AACATCCGCA GCACTTTCCA CGGCGGGCAG GTCCGGGACC GGAGAGGAAC CTCGCACAAC 1740

GGACCGCCTA CCTCCCCCAC GCTGTCCCAT GATGCCACGC CGCTGCCTCA GAGCCGCAGC 1800

AGAGCCACGT CCAACCTCTT TAGCAAACTA ACGTCCAAAC TCACCAGAAG AAGAAAACCA 1860

TGGGAGAGAG AGAGAGACAG AGAGATGGAG GGAGGAGAGA GAAACAGAGA GAGGGAGCAA 1920

AGAGATCCTG AAAAAAAAGA AACAGAGCCC AGGTTGCTCC GACTTACCTG GAATGTGAAG 1980

ATCACGAGCT GCAAAGACCC CGAGGACATG ATGGCAGCGA TTCGCCGCAC CGCCGACGCC 2040

AACAGTTGCC AACACCGCCA AACGGAGCCC TTCCTGCTGA GTTGCAGCCA TGGCAGAGAC 2100

AACACGGACC AGTACTCCCA GTTTGAGGTG GAGGTGTGCC GGCTGCAAAG GCTCGGCGTC 2160

AATGGGGTTC GGTTCCGACG CGTCTCGGGG ACCTTCCTGG CTTTCAGGAA CATTGCGACC 2220

AAAATCTCCA ACGAACTGCA GCTTTAA 2247

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkklseeslekikrEieilkklkhpni  60

         y+llkt+G+g+f+kVkla+h +t+++va+Kii+k++l+ +sl+k++rE++i+k l+hpni

Q: 56    YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKGLNHPNI  115

         99**********************************************************

S: 61    ikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgiv  120

         +kl+eviet+k+lylv+eyasgge+fdy++++gr+kekear+ f+q+vsav+Y+h+k+iv

Q: 116   VKLFEVIETEKTLYLVMEYASGGEVFDYLVSHGRMKEKEARSKFRQIVSAVHYCHQKNIV  175

         ************************************************************

S: 121   HrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkvD  180

         HrDlK+eNllld++ nikiaDFG++n+f+ g++l+tfcGsppYaaPel++gkkY+gp+vD

Q: 176   HRDLKAENLLLDADANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVD  235

         ************************************************************

S: 181   vWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpekR  240

         +WslGv+Ly+lv+g+lPfd++nlkel+e++l+gk+++p+++s+++e++lr++Lv +p+kR

Q: 236   IWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRVPFYMSTDCENILRRFLVLNPSKR  295

         ************************************************************

S: 241   atieeilkhewl  252

         +t+e+i+k++w+

Q: 296   CTLEQIMKDKWI  307

         ***********7

Domain Sequence
(FASTA)

YRLLKTIGKG NFAKVKLARH ILTGREVAIK IIDKTQLNPT SLQKLFREVR IMKGLNHPNI 60

VKLFEVIETE KTLYLVMEYA SGGEVFDYLV SHGRMKEKEA RSKFRQIVSA VHYCHQKNIV 120

HRDLKAENLL LDADANIKIA DFGFSNEFTL GSKLDTFCGS PPYAAPELFQ GKKYDGPEVD 180

IWSLGVILYT LVSGSLPFDG QNLKELRERV LRGKYRVPFY MSTDCENILR RFLVLNPSKR 240

CTLEQIMKDK WI 252

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Loxodonta africana"; ?>Macropus eugenii"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR001772	; Kinase-assoc_KA1.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF02149	; KA1; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50032	; KA1; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013