EKS-LAC-00234

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LAC-00234

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/PKN	516.0	2.0E-155	618	877	260

Status

Unreviewed

Ensembl Protein

ENSLACP00000016887

UniProt Accession

H3B4R6;

Protein Name

Protein Synonyms/Alias

Gene Name

PKN3

Gene Synonyms/Alias

PKN3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000014875	ENSLACP00000016887	ENSLACT00000017006

Organism

Latimeria chalumnae

Functional Description

Protein Length

956

Protein Sequence
(FASTA)

DLLDPDFQQK LEVMKEQIRR DIQKELKIKE GAENLRKVTT DKKNLVHVEH QLKETNRNLE 60

QLHWELQELN TRIVVKDKEN RAGGHRKKKL KIYNFPCTCK KKKKKKIILM CRLCLPLSPK 120

YGVEHCIQLF VLRTVKDRKM LAAAQQMLQD SKTKIELIRM QIVKVTNSMG CPDDDLDTIV 180

SPLELRIEEL RHHLRIESAV AEGAKNVVKL LGGGRGQDRK PLAQPHTHRK QGTNHFQLTV 240

HCVEEVLLLL PQCLFKKNKS PELLSTSSTD RSYCCTAHFS SVLCMYHSIG TLEVHLMGCQ 300

DLLESVPGRS RMNMAPGSPA DPRSLLRARA GMGIHGRSAA SRYLKADELS TEIGAVLKLD 360

SKVVGQTCWR SVSNQAWDQS FIVELDRKSR ELEIAILWRD WRQLCAVKFL RLDDFLDNQR 420

HGMCLYLEPQ GMLFAEVTFS NPAIEWHSKL QRQKRIFAKH KGKDFLRAPQ LNINIATWGR 480

LMMSVLPPCS TMTTLSPPLP APPISMDTDF ISPAPRHHNA EMSSPLRDLP VVKLTFSEEL 540

PPKPPHIFLH TEPDSRMLSP VVTPVISIKS VFKCPRAKNK LLPSQEQLYF PGVGQTGTSQ 600

RNLMDLPCRR QVMELEDFHC ISMLGRGHFG KVLLAEHKLM GKLFAIKALK KGDIVARDEM 660

DSLMCEKRIF ETVNSSQHPF LVNLFACFQT PNHVCFVMEY MPGGDLMMHI HSNVFSEPRA 720

RFYAACVVLG LQFLHEKKII YRDLKLDNLL LDSDGFVKIA DFGLCKEGMG FGDHTGTFCG 780

TPEFMAPEVL TETTYTRAVD WWGLGVLIYE MLVGESPFPG DDEEEVFDSI VNDEVCYPRF 840

LSTEAIAIIR KLLRKNPERR LGAGEGDAEE VKKQMFFQEI DWDALFAKKA KPPFIPKIAS 900

PSDVSNFDKE FTTQKAVLTP PHEPRALTAQ EQAQFKSFDY VSDLCLEVHP GKVKRR 956

Nucleotide Sequence
(FASTA)

GACCTCCTTG ATCCGGATTT CCAGCAGAAA CTGGAGGTTA TGAAGGAGCA GATCCGGCGG 60

GACATTCAGA AGGAGCTCAA GATCAAAGAG GGAGCAGAAA ACCTGCGGAA AGTCACCACC 120

GACAAGAAGA ACCTGGTCCA TGTGGAGCAC CAGCTAAAAG AGACCAACAG GAACCTGGAA 180

CAGCTGCACT GGGAGCTTCA GGAGCTAAAC ACTCGAATCG TTGTCAAAGA TAAAGAAAAC 240

AGAGCAGGTG GGCATAGGAA GAAAAAGCTG AAAATCTACA ATTTCCCATG TACCTGTAAA 300

AAAAAAAAAA AAAAAAAAAT TATATTGATG TGTAGGCTCT GTCTTCCTCT TTCACCAAAA 360

TATGGGGTTG AGCACTGCAT ACAATTATTT GTATTGCGTA CTGTTAAGGA TCGCAAAATG 420

TTGGCGGCGG CGCAGCAGAT GCTGCAGGAC AGTAAAACGA AGATCGAGCT GATCCGGATG 480

CAAATTGTAA AAGTGACAAA TTCCATGGGA TGTCCGGATG ACGACCTGGA CACAATTGTG 540

AGCCCACTGG AGCTGCGAAT TGAGGAGCTG AGACACCACC TGCGCATCGA GTCAGCGGTG 600

GCGGAGGGAG CAAAAAATGT GGTGAAGCTG CTCGGAGGTG GGAGGGGCCA GGATCGCAAG 660

CCACTGGCAC AGCCCCACAC ACACAGGAAG CAGGGCACTA ATCATTTTCA ACTTACTGTA 720

CATTGTGTGG AGGAGGTGCT TCTGCTTTTA CCCCAGTGTT TATTTAAAAA AAATAAAAGT 780

CCTGAGCTGC TTAGCACATC ATCCACTGAT CGATCTTACT GCTGTACTGC CCACTTCAGT 840

TCTGTGTTGT GTATGTATCA TTCCATAGGC ACTTTGGAGG TTCATCTGAT GGGCTGTCAG 900

GATCTTTTGG AAAGTGTTCC AGGACGCTCC CGGATGAACA TGGCTCCGGG CAGCCCCGCC 960

GACCCCAGGT CGTTGCTGAG GGCTCGTGCA GGGATGGGCA TTCACGGGCG CAGTGCAGCC 1020

AGCCGTTACC TGAAAGCTGA CGAACTAAGC ACTGAGATTG GTGCCGTTCT GAAGCTGGAC 1080

AGTAAGGTTG TCGGACAGAC TTGCTGGCGG TCAGTCAGTA ACCAGGCCTG GGATCAGAGC 1140

TTCATCGTTG AGCTGGACAG GAAGTCCCGG GAGCTGGAAA TTGCAATTTT GTGGCGGGAT 1200

TGGCGCCAGC TCTGCGCCGT GAAGTTTCTT CGCTTGGATG ACTTTCTTGA TAACCAGCGG 1260

CACGGGATGT GCCTCTACCT CGAACCCCAG GGGATGCTGT TTGCAGAGGT GACCTTTAGT 1320

AACCCAGCAA TTGAGTGGCA TTCAAAGTTG CAACGACAGA AACGGATCTT TGCAAAACAC 1380

AAAGGGAAGG ATTTTCTCCG AGCGCCTCAA CTAAACATTA ACATTGCTAC CTGGGGGCGG 1440

CTGATGATGA GTGTCCTTCC TCCCTGCAGC ACAATGACAA CACTAAGCCC GCCCCTTCCT 1500

GCTCCTCCCA TTTCCATGGA CACCGACTTT ATTTCCCCGG CCCCAAGACA CCACAATGCA 1560

GAAATGTCCT CCCCTCTAAG GGATCTCCCG GTGGTTAAGC TGACGTTCAG TGAGGAACTC 1620

CCACCCAAAC CTCCACATAT TTTTCTGCAC ACAGAGCCTG ATAGTAGGAT GCTGTCGCCA 1680

GTGGTGACCC CGGTAATCTC AATCAAAAGT GTTTTTAAAT GTCCCAGGGC AAAAAATAAG 1740

CTACTACCCT CTCAAGAGCA GCTGTATTTT CCTGGGGTCG GACAAACTGG AACCAGTCAA 1800

AGAAATCTCA TGGATTTGCC TTGCAGGAGA CAAGTGATGG AGCTGGAAGA CTTCCACTGT 1860

ATCTCCATGT TGGGCCGCGG ACACTTCGGA AAGGTCCTGT TAGCAGAGCA CAAGCTGATG 1920

GGGAAACTAT TTGCCATCAA AGCGCTGAAG AAAGGTGACA TTGTGGCTCG GGATGAGATG 1980

GACAGCTTGA TGTGTGAGAA GCGGATCTTT GAGACGGTGA ACTCCTCCCA ACACCCATTC 2040

CTGGTAAATC TCTTTGCATG CTTCCAGACC CCGAATCACG TGTGTTTTGT GATGGAGTAC 2100

ATGCCAGGGG GAGACCTCAT GATGCACATT CACTCCAACG TGTTCTCAGA GCCCAGGGCA 2160

CGGTTTTACG CAGCCTGTGT TGTTCTGGGG TTACAGTTTC TCCATGAGAA GAAAATCATC 2220

TACAGAGACC TGAAGTTGGA CAACTTGTTG TTGGATTCAG ATGGTTTTGT TAAAATTGCT 2280

GACTTTGGAC TCTGCAAAGA AGGAATGGGC TTCGGGGACC ACACTGGTAC ATTCTGTGGG 2340

ACCCCCGAGT TCATGGCTCC CGAGGTGCTG ACGGAGACCA CCTACACTCG AGCTGTAGAC 2400

TGGTGGGGTC TCGGGGTCCT CATTTACGAG ATGTTGGTTG GAGAGTCTCC ATTTCCAGGG 2460

GATGATGAAG AGGAGGTGTT TGACAGCATT GTCAATGACG AAGTCTGCTA TCCACGATTT 2520

CTTTCTACGG AGGCAATTGC CATCATAAGG AAGCTTCTGC GCAAAAACCC AGAGCGCCGA 2580

CTTGGAGCTG GAGAAGGTGA TGCGGAGGAG GTCAAGAAGC AGATGTTCTT CCAGGAGATC 2640

GACTGGGATG CCTTATTTGC TAAGAAAGCG AAGCCCCCTT TTATCCCCAA AATAGCCAGT 2700

CCCTCTGATG TCAGCAACTT TGACAAGGAA TTCACCACCC AGAAGGCAGT TCTCACACCA 2760

CCCCATGAGC CGCGGGCACT CACTGCACAG GAGCAAGCCC AATTTAAAAG CTTTGACTAT 2820

GTCTCCGACC TCTGTCTGGA AGTGCACCCT GGGAAGGTCA AGCGGAGATG A 2871

Domain Profile

S: 1     frllavlgrghfgkvllseykstgelyaikalkkgdilardevesllcekrileavssvr  60

         f+++++lgrghfgkvll+e+k  g+l+aikalkkgdi+arde++sl+cekri+e+v+s +

Q: 618   FHCISMLGRGHFGKVLLAEHKLMGKLFAIKALKKGDIVARDEMDSLMCEKRIFETVNSSQ  677

         89**********************************************************

S: 61    hpflvnllacfqtkehvcfvmeyaaggdlmlhihedvfsepravfyaacvvlglqflhek  120

         hpflvnl+acfqt +hvcfvmey++ggdlm+hih++vfsepra fyaacvvlglqflhek

Q: 678   HPFLVNLFACFQTPNHVCFVMEYMPGGDLMMHIHSNVFSEPRARFYAACVVLGLQFLHEK  737

         ************************************************************

S: 121   kivyrdlkldnllldtegyvkiadfglckeglgygdrtstfcgtpeflapevltetsytr  180

         ki+yrdlkldnllld++g+vkiadfglckeg+g+gd+t+tfcgtpef+apevltet+ytr

Q: 738   KIIYRDLKLDNLLLDSDGFVKIADFGLCKEGMGFGDHTGTFCGTPEFMAPEVLTETTYTR  797

         ************************************************************

S: 181   avdwwglgvllyemlvgespfpgddeeevfdsivndevryprflsveaieilrrllrknp  240

         avdwwglgvl+yemlvgespfpgddeeevfdsivndev yprfls+eai+i+r+llrknp

Q: 798   AVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVCYPRFLSTEAIAIIRKLLRKNP  857

         ************************************************************

S: 241   ekrlgaserdaedvkkqpff  260

         e+rlga+e dae+vkkq ff

Q: 858   ERRLGAGEGDAEEVKKQMFF  877

         *******************9

Domain Sequence
(FASTA)

FHCISMLGRG HFGKVLLAEH KLMGKLFAIK ALKKGDIVAR DEMDSLMCEK RIFETVNSSQ 60

HPFLVNLFAC FQTPNHVCFV MEYMPGGDLM MHIHSNVFSE PRARFYAACV VLGLQFLHEK 120

KIIYRDLKLD NLLLDSDGFV KIADFGLCKE GMGFGDHTGT FCGTPEFMAP EVLTETTYTR 180

AVDWWGLGVL IYEMLVGESP FPGDDEEEVF DSIVNDEVCY PRFLSTEAIA IIRKLLRKNP 240

ERRLGAGEGD AEEVKKQMFF 260

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Danio rerio"; ?>Gallus gallus"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Oreochromis niloticus"; ?>Pelodiscus sinensis"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Xenopus tropicalis"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005622	; C:intracellular
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007165	; P:signal transduction

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR000008	; C2_Ca-dep.
IPR008973	; C2_Ca/lipid-bd_dom_CaLB.
IPR011072	; HR1_rho-bd.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF02185	; HR1; 1.
PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00239	; C2; 1.
SM00742	; Hr1; 3.
SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013