EKS-LAC-00423

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LAC-00423

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/IRAK	286.4	2.8E-85	235	452	218

Status

Unreviewed

Ensembl Protein

ENSLACP00000018448

UniProt Accession

H3B977;

Protein Name

Protein Synonyms/Alias

Gene Name

IRAK4

Gene Synonyms/Alias

IRAK4;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000016246	ENSLACP00000018448	ENSLACT00000018581

Organism

Latimeria chalumnae

Functional Description

Protein Length

454

Protein Sequence
(FASTA)

MSKPITSSMY VRCLNHGLIR QLADFLDPQD AWKTIAVAIK KPTGEPRYNQ FHIRRFEGLV 60

HAGKSPTCEL LFDWGTTNCK VGDLVDLLIR NQLLAAASLL LPENLPQDAV GAMPSSRIPL 120

ESQPTLPFHE KETVLVPNMT EPQFPTPDST SDHKSSGADC DTGKVHFQLN ELTNSKNIFI 180

NLFFILNLLL ESIFGPGCVK LDSLSLHSHN HFTDVVAKDL KGFFVLFFTL CFPCFCRCQH 240

ENLVEMIGFS NDGDHSCLIY AYMPNGSLLD RLACLDGTAP LSWSTRCNIT WGTANGIKYL 300

HDNNHIHRDI KSANILLNDL FVPKISDFGL ARASAQLTQT VMTEKIVGTA AYMAPEALRG 360

EVTPKSDVFS FGVVLLEIIT GLSAVDENRE PQLLLDIKEE IEDEEMTLED YIDKKMETWD 420

SAAVEKVYSI ACQCLHERKN KRPDIKSVCE LLQA 454

Nucleotide Sequence
(FASTA)

ATGAGCAAAC CTATAACTTC CTCAATGTAT GTTCGATGTC TAAACCATGG GCTGATCAGA 60

CAATTAGCAG ATTTTCTGGA TCCGCAGGAT GCATGGAAGA CGATAGCTGT GGCTATTAAA 120

AAGCCAACAG GAGAACCAAG ATACAACCAG TTTCACATAA GGAGATTTGA AGGACTAGTT 180

CATGCAGGAA AGAGTCCCAC ATGTGAATTA CTTTTCGACT GGGGAACAAC AAACTGCAAA 240

GTTGGTGATC TTGTGGACTT GCTAATAAGG AATCAGCTTC TAGCAGCTGC AAGTCTTTTG 300

CTTCCAGAAA ACCTCCCTCA AGATGCTGTG GGTGCCATGC CTTCCTCTAG AATACCTCTG 360

GAGTCCCAAC CAACTCTTCC TTTCCATGAG AAAGAGACTG TATTAGTGCC CAACATGACT 420

GAGCCGCAAT TTCCCACGCC AGACAGCACT AGTGATCACA AAAGCAGTGG TGCTGACTGT 480

GACACAGGTA AAGTACATTT TCAGTTAAAT GAATTAACTA ATTCCAAGAA CATTTTTATA 540

AATCTGTTTT TTATTTTAAA TCTCCTACTA GAGAGCATAT TTGGGCCAGG ATGTGTGAAA 600

CTTGATAGCC TGTCACTGCA CAGTCATAAT CACTTTACAG ATGTGGTAGC AAAGGATTTA 660

AAGGGGTTTT TTGTTTTGTT TTTTACACTA TGTTTTCCCT GTTTCTGCAG ATGCCAGCAT 720

GAAAATCTAG TTGAAATGAT TGGATTCTCT AATGATGGGG ATCATTCTTG CTTGATTTAT 780

GCTTATATGC CTAATGGCTC ATTACTGGAT CGACTGGCCT GTTTAGATGG AACTGCACCT 840

CTTTCATGGA GTACAAGGTG TAACATTACT TGGGGTACGG CAAATGGCAT AAAATATTTA 900

CATGACAATA ATCATATTCA TAGAGATATT AAAAGCGCAA ACATTTTGCT GAATGACTTG 960

TTTGTGCCCA AGATTTCTGA CTTTGGTCTT GCCCGGGCTT CAGCACAGCT GACACAGACA 1020

GTCATGACTG AGAAAATAGT AGGAACAGCA GCTTATATGG CCCCTGAGGC ACTGCGTGGG 1080

GAGGTCACAC CCAAATCAGA TGTTTTTAGC TTTGGTGTGG TCTTGCTGGA GATAATAACA 1140

GGACTTTCAG CAGTTGATGA AAATCGGGAG CCACAGTTAC TGCTTGACAT TAAGGAAGAA 1200

ATTGAAGATG AAGAAATGAC CTTAGAAGAT TATATTGATA AAAAAATGGA GACTTGGGAT 1260

TCTGCAGCAG TTGAGAAAGT ATACTCTATA GCCTGCCAGT GCCTTCATGA AAGAAAAAAT 1320

AAGAGACCGG ACATAAAATC GGTCTGTGAA CTACTACAAG CATGA 1365

Domain Profile

S: 52    larfrHdnilellgysaeseklcLvYqymknGsLedrLqcqkgsepLsWpqRlsillGta  111

         + r++H+n++e++g+s ++++ cL+Y+ym+nGsL drL c +g++pLsW +R++i+ Gta

Q: 235   FCRCQHENLVEMIGFSNDGDHSCLIYAYMPNGSLLDRLACLDGTAPLSWSTRCNITWGTA  294

         679*********************************************************

S: 112   raiefLHeaspslihgdiksaNiLLDekltpKlgDfglarfapesekqsstvlrtskvrg  171

         ++i++LH++  ++ih+diksaNiLL + + pK++Dfglar   +s++ ++tv+ t+k++g

Q: 295   NGIKYLHDN--NHIHRDIKSANILLNDLFVPKISDFGLAR---ASAQLTQTVM-TEKIVG  348

         *********..*****************************...8999999999.******

S: 172   tlaYlpeefirvgqltvkvDvySfGiVllEvltGlravdedrktkyLkdllkeeieeekv  231

         t+aY+++e++r g++t k+Dv+SfG+VllE++tGl avde+r+++ L+d+ keeie+e+

Q: 349   TAAYMAPEALR-GEVTPKSDVFSFGVVLLEIITGLSAVDENREPQLLLDI-KEEIEDEE-  405

         ***********.*************************************9.********.

S: 232   eilekfldkkagkleeellealielalaclaekakkrPtmsqvlell  278

          +le+++dkk+ + +++ +e+++++a++cl+e+++krP+++ v ell

Q: 406   MTLEDYIDKKMETWDSAAVEKVYSIACQCLHERKNKRPDIKSVCELL  452

         689****************************************9876

Domain Sequence
(FASTA)

FCRCQHENLV EMIGFSNDGD HSCLIYAYMP NGSLLDRLAC LDGTAPLSWS TRCNITWGTA 60

NGIKYLHDNN HIHRDIKSAN ILLNDLFVPK ISDFGLARAS AQLTQTVMTE KIVGTAAYMA 120

PEALRGEVTP KSDVFSFGVV LLEIITGLSA VDENREPQLL LDIKEEIEDE EMTLEDYIDK 180

KMETWDSAAV EKVYSIACQC LHERKNKRPD IKSVCELL 218

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>