EKS-LAC-00219

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LAC-00219

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	468.4	6.9E-141	4	287	284

Status

Unreviewed

Ensembl Protein

ENSLACP00000018492

UniProt Accession

H3B9C1;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL3

Gene Synonyms/Alias

CDKL3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000016283	ENSLACP00000023087	ENSLACT00000026014
ENSLACG00000016283	ENSLACP00000018492	ENSLACT00000018625

Organism

Latimeria chalumnae

Functional Description

Protein Length

531

Protein Sequence
(FASTA)

MELYENLGMV GEGSYGMVMK CRHKESRQIV AIKKFLEKDD DKSVKKIAMR EIKFLKQFRH 60

ENLVNLIEVF RQKKRLFLVF EFIDHTVLDE LDQFPRGLDN KKIRKYLFQV LRALVYLHDN 120

QIIHRDIKPE NVLVSQSGIV KLCDFGFART LAAPGEVYTD YVATRWYRAP ELLVGDPMYG 180

KPVDIWALGC MIIEMCTGNP FLPGNSDLDQ LHRIVTKVGN LTPHLQDLFS RSLAFTGMHL 240

PEIQHSKSPR KKFPRLHPLL AEIVHLSLQI DPANRVSSTE LIHHEYFTRD GFAEKFVIEI 300

HAKILKDSKD NPLLKARENS SENEQLFENV EIYQLSQSPS DFWIHGDDIE KEKKSSDTKT 360

DEKALKEKGS KGEIKSEQVD RATEQKPVTK STGLSLDSQP ESEGMGTKVP GHTPISTTMP 420

PINPSNGHLV ATIANTMLNS ESTGARTHEK AKKRRSPLQT LGHLTIGNQQ GDGSPSHVQH 480

ERNIIHERAL YIEQMLNANK KKTKAPKPEK EEVRFPELPL IGQQMELKGI E 531

Nucleotide Sequence
(FASTA)

ATGGAGCTGT ACGAAAATCT GGGAATGGTG GGGGAAGGCA GCTATGGAAT GGTAATGAAA 60

TGCAGACACA AGGAAAGTAG GCAGATTGTG GCCATCAAGA AATTTCTGGA GAAAGATGAT 120

GACAAGTCGG TCAAGAAAAT TGCAATGAGA GAAATCAAAT TTCTAAAGCA ATTTCGTCAC 180

GAAAACCTAG TGAATCTGAT TGAAGTGTTT AGACAGAAAA AGCGTCTGTT TTTGGTGTTT 240

GAATTCATTG ACCACACCGT CCTAGATGAA CTGGACCAGT TTCCCCGTGG GCTGGACAAT 300

AAGAAGATCC GAAAATATCT GTTCCAAGTC CTTAGGGCGT TGGTGTACCT TCACGACAAT 360

CAAATAATTC ATCGAGATAT CAAGCCAGAG AACGTGTTAG TCTCACAGTC TGGAATCGTT 420

AAGCTATGCG ATTTTGGCTT TGCCCGAACC CTGGCAGCAC CAGGGGAAGT CTATACGGAT 480

TACGTGGCTA CCCGATGGTA CAGAGCTCCA GAGCTGTTAG TAGGAGATCC AATGTACGGC 540

AAACCTGTGG ACATCTGGGC GTTGGGCTGC ATGATCATTG AAATGTGTAC TGGCAACCCC 600

TTTCTACCTG GCAACTCTGA CCTGGACCAA CTCCACAGAA TTGTTACCAA AGTAGGGAAT 660

CTGACTCCTC ATCTTCAGGA CCTTTTCTCT AGGAGTCTAG CATTTACTGG GATGCATCTT 720

CCAGAAATCC AACACTCCAA GTCTCCTAGG AAGAAGTTTC CCAGGCTCCA TCCTTTATTG 780

GCAGAAATAG TGCATTTATC CTTGCAAATA GACCCAGCTA ATAGGGTGTC GTCCACAGAA 840

CTGATACATC ATGAATATTT CACCAGAGAT GGCTTTGCTG AAAAATTTGT TATAGAGATA 900

CATGCCAAAA TTCTAAAGGA CTCAAAGGAT AATCCTCTTT TGAAAGCCAG AGAGAATAGC 960

AGTGAAAATG AACAGCTGTT TGAAAACGTG GAAATCTACC AGTTGTCCCA GTCACCCTCT 1020

GATTTCTGGA TTCATGGTGA TGATATTGAA AAGGAGAAGA AATCCTCCGA TACCAAGACT 1080

GACGAGAAGG CACTGAAAGA AAAAGGCTCT AAAGGAGAGA TAAAGTCAGA GCAGGTGGAC 1140

AGAGCCACTG AACAGAAACC TGTCACAAAG TCAACAGGTT TGTCTTTGGA TAGCCAGCCA 1200

GAGTCTGAGG GGATGGGGAC AAAGGTACCT GGACATACAC CAATCAGCAC TACCATGCCT 1260

CCTATCAATC CCAGTAATGG TCACCTTGTG GCCACCATTG CCAACACAAT GCTCAATTCT 1320

GAATCTACAG GTGCAAGGAC ACATGAGAAA GCCAAAAAAA GGAGGAGTCC GCTGCAGACA 1380

CTGGGACATT TAACCATTGG CAATCAGCAA GGGGACGGAT CCCCATCTCA CGTTCAGCAC 1440

GAGAGGAATA TTATCCATGA ACGGGCACTC TATATAGAGC AGATGCTAAA TGCAAACAAG 1500

AAAAAAACAA AGGCTCCCAA ACCGGAGAAG GAGGAAGTCC GTTTCCCAGA GCTGCCTCTT 1560

ATAGGACAGC AGATGGAGCT GAAGGGAATT GAA 1593

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         ye+lg vGeGsyG+v+kcr+k++ qivaikkfle++ddk+vkkia+reik+lkq++henl

Q: 4     YENLGMVGEGSYGMVMKCRHKESRQIVAIKKFLEKDDDKSVKKIAMREIKFLKQFRHENL  63

         9***********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnl+evfr+kk+l+lvfe++d+tvldel+++p+G+++++++k+l+q+l+a+ ++h n+ii

Q: 64    VNLIEVFRQKKRLFLVFEFIDHTVLDELDQFPRGLDNKKIRKYLFQVLRALVYLHDNQII  123

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrdikpen+l+s+sg+vklcdfGfar+laapg+vytdyvatrwyrapellvgd  yGk+v

Q: 124   HRDIKPENVLVSQSGIVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDPMYGKPV  183

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         d+wa+Gc+++e+ tG+p++pg+sd+dql++i++++G+l+p+ q++fs++  f+G++lpe+

Q: 184   DIWALGCMIIEMCTGNPFLPGNSDLDQLHRIVTKVGNLTPHLQDLFSRSLAFTGMHLPEI  243

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         ++ +s +kk+p+l+++l+++++  l++dpa+r+s++el++heyf

Q: 244   QHSKSPRKKFPRLHPLLAEIVHLSLQIDPANRVSSTELIHHEYF  287

         *******************************************9

Domain Sequence
(FASTA)

YENLGMVGEG SYGMVMKCRH KESRQIVAIK KFLEKDDDKS VKKIAMREIK FLKQFRHENL 60

VNLIEVFRQK KRLFLVFEFI DHTVLDELDQ FPRGLDNKKI RKYLFQVLRA LVYLHDNQII 120

HRDIKPENVL VSQSGIVKLC DFGFARTLAA PGEVYTDYVA TRWYRAPELL VGDPMYGKPV 180

DIWALGCMII EMCTGNPFLP GNSDLDQLHR IVTKVGNLTP HLQDLFSRSL AFTGMHLPEI 240

QHSKSPRKKF PRLHPLLAEI VHLSLQIDPA NRVSSTELIH HEYF 284

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Vicugna pacos"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013