EKS-LAC-00266

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LAC-00266

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	281.4	6.8E-84	9	265	257

Status

Unreviewed

Ensembl Protein

ENSLACP00000018986

UniProt Accession

H3BAR5;

Protein Name

Protein Synonyms/Alias

Gene Name

CHEK1

Gene Synonyms/Alias

CHEK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000016703	ENSLACP00000018986	ENSLACT00000019119

Organism

Latimeria chalumnae

Functional Description

Protein Length

475

Protein Sequence
(FASTA)

MAVPFVKDWD LVQTLGEGAY GEVQLAVNRQ TEEAVAVKIV DMSRAADCPE NIKKEICINK 60

MLSHDSIVKF YGHRREGNIQ YLFLEYCSGG ELFDRIEPDV GMPEPAAHKF FQQLIAGVEY 120

LHSIGITHRD IKPENLLLDD KDNLKISDFG LATVFKHNGR ERQLKKMCGT LPYVAPELLK 180

CKEFSAEPVD IWSCGIVLTA MLAGELPWDQ PSEGCQEYSD WLAKKLYVTP WKKIDAMPLA 240

LLTKTLLQNP KDRITILNIK KDRWYTRSFQ GVKRTRVSSG GVNDSPGPFS KHIRSDMDLS 300

PISSPNSDDS VRFSRSQPEP RTIFPSWDST PSCINNLIQG ISFSQPTCPD HMLLNSQLLG 360

TPGSSQNPWQ RLVKRMTRFF TKLDASHSCS ALKKVCEKMG YMWKMNCVNQ VTLSTKDRRN 420

NQLIFKVNLL EMEEKTLMDF RLSKGDGLEF KRHFLKIKGR LIDIVSSQRL TLSAT 475

Nucleotide Sequence
(FASTA)

ATGGCTGTTC CCTTTGTAAA AGATTGGGAC TTGGTACAGA CCTTGGGAGA AGGGGCGTAT 60

GGAGAAGTGC AGCTTGCTGT AAACAGACAG ACTGAGGAAG CTGTTGCAGT TAAAATTGTT 120

GACATGAGTC GAGCCGCAGA CTGTCCCGAG AACATTAAGA AAGAGATCTG TATTAATAAA 180

ATGTTAAGCC ATGACAGCAT TGTGAAGTTC TATGGACACC GACGGGAAGG CAACATCCAG 240

TACCTGTTTT TGGAGTACTG TAGCGGAGGA GAGCTTTTTG ATAGAATTGA GCCAGATGTG 300

GGAATGCCTG AACCAGCAGC ACATAAATTT TTCCAGCAAC TGATTGCAGG AGTGGAGTAC 360

CTCCACAGTA TAGGGATAAC TCACAGAGAC ATTAAACCTG AGAATCTGCT GCTGGATGAC 420

AAAGATAATT TGAAGATCTC CGACTTTGGC TTAGCAACGG TATTCAAACA CAATGGACGG 480

GAGAGGCAGT TGAAAAAGAT GTGTGGAACT CTCCCGTACG TTGCACCAGA ATTGCTGAAG 540

TGCAAAGAGT TTTCTGCTGA GCCAGTTGAT ATCTGGTCCT GCGGTATTGT ACTCACCGCC 600

ATGTTAGCAG GGGAATTACC TTGGGACCAG CCCAGTGAGG GCTGTCAAGA ATACAGTGAT 660

TGGCTTGCTA AGAAACTCTA CGTGACGCCA TGGAAAAAAA TAGATGCCAT GCCACTAGCT 720

CTCCTTACTA AGACTTTGTT ACAGAATCCT AAAGACAGAA TTACTATACT TAATATCAAA 780

AAGGACAGGT GGTATACCAG ATCTTTTCAA GGTGTTAAGA GAACACGGGT TTCATCAGGC 840

GGAGTTAACG ACTCACCTGG ACCCTTTTCT AAGCATATCC GTTCTGATAT GGACCTGTCT 900

CCTATTTCCA GCCCCAACAG TGATGATTCG GTGAGGTTTT CCAGATCTCA GCCGGAGCCA 960

CGGACTATTT TCCCATCGTG GGACAGCACT CCCTCTTGTA TTAATAATCT GATACAGGGG 1020

ATCAGCTTCT CCCAGCCGAC CTGCCCTGAT CACATGCTTC TCAACAGCCA GTTACTAGGC 1080

ACTCCAGGTT CCTCCCAGAA CCCTTGGCAG CGTTTGGTAA AAAGAATGAC CCGGTTTTTT 1140

ACTAAACTGG ACGCCAGCCA CTCCTGCTCA GCCCTGAAGA AAGTATGTGA GAAAATGGGC 1200

TACATGTGGA AAATGAACTG TGTGAACCAG GTAACACTGT CCACCAAAGA CAGACGCAAC 1260

AACCAACTTA TCTTCAAAGT AAACCTGTTG GAAATGGAAG AGAAGACCCT CATGGACTTC 1320

CGCCTCTCAA AGGGAGATGG TTTGGAGTTC AAGAGGCATT TCCTTAAGAT CAAAGGCAGA 1380

CTGATTGACA TTGTGAGCAG CCAGAGACTG ACCCTTTCTG CCACATGA 1428

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkklseeslekikrEieilkklkhpni  60

         ++l++tlGeg++g+V+la++++t+e+vavKi++ +++  +  e+ik+Ei i k+l+h  i

Q: 9     WDLVQTLGEGAYGEVQLAVNRQTEEAVAVKIVDMSRAA-DCPENIKKEICINKMLSHDSI  67

         7899******************************7775.5579*****************

S: 61    ikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgiv  120

         +k++   ++ +  yl+ley+sggeLfd+ie +  ++e  a+k+f+ql+++v+Ylhs gi+

Q: 68    VKFYGHRREGNIQYLFLEYCSGGELFDRIEPDVGMPEPAAHKFFQQLIAGVEYLHSIGIT  127

         ************************************************************

S: 121   HrDlKpeNllldkkenikiaDFGlanlfkeg...klletfcGsppYaaPellkgkkYegp  177

         HrD+KpeNllld+k+n+ki+DFGla++fk++   ++l+++cG++pY+aPellk k+++++

Q: 128   HRDIKPENLLLDDKDNLKISDFGLATVFKHNgreRQLKKMCGTLPYVAPELLKCKEFSAE  187

         **************************999988889*************************

S: 178   kvDvWslGvvLyalvtgklPfdee..nlkellekilkgkleipkk.lskelesLlrklLv  234

         +vD+Ws+G+vL a+++g+lP+d++   ++e+++++ k+ + +p k +++    Ll+k L

Q: 188   PVDIWSCGIVLTAMLAGELPWDQPseGCQEYSDWLAKKLYVTPWKkIDAMPLALLTKTLL  247

         ***********************95559999999999999999888**************

S: 235   vdpekRatieeilkhewl  252

         ++p+ R+ti +i+k++w+

Q: 248   QNPKDRITILNIKKDRWY  265

         *****************5

Domain Sequence
(FASTA)

WDLVQTLGEG AYGEVQLAVN RQTEEAVAVK IVDMSRAADC PENIKKEICI NKMLSHDSIV 60

KFYGHRREGN IQYLFLEYCS GGELFDRIEP DVGMPEPAAH KFFQQLIAGV EYLHSIGITH 120

RDIKPENLLL DDKDNLKISD FGLATVFKHN GRERQLKKMC GTLPYVAPEL LKCKEFSAEP 180

VDIWSCGIVL TAMLAGELPW DQPSEGCQEY SDWLAKKLYV TPWKKIDAMP LALLTKTLLQ 240

NPKDRITILN IKKDRWY 257

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013