EPS-LAC-00076

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-LAC-00076

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/PTEN	262.1	3.8E-78	100	271	172

Status

Unreviewed

Ensembl Protein

ENSLACP00000019393

UniProt Accession

H3BBX2;

Protein Name

Protein Synonyms/Alias

Gene Name

TENC1

Gene Synonyms/Alias

TENC1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000017057	ENSLACP00000019393	ENSLACT00000019528
ENSLACG00000017057	ENSLACP00000019392	ENSLACT00000019527

Organism

Latimeria chalumnae

Functional Description

Protein Length

514

Protein Sequence
(FASTA)

MIKPGKTDPH SFKEKAFKKK KPCAGCKQPV EGQGVTCRVC KVICHKKCES KIPPACQPPP 60

VTELQRRGTA PARHIQHLGS TKSLNTTKQR STLPRSFSVD RVMERNYDFD LTYITERIIS 120

VFFPPALEEQ RYRGNLKEVA QMLKSKHDDK YLLFNLSEKR HDISRLNPKV HNFGWPNLHA 180

PPLDKICAIC KSMETWLNSD PQHVVVLHCK GNKGKTGVIV AAYMHYSKIS AGADQALSTL 240

AMRKFCEDKV SSSLQPSQTR YIYYFGGLLS GAIKMNSSPL FLHHVLIPAI PNFEPSAAAG 300

YHPFLKIYQS MQLVYTSGIY NIQGVVTRKL CITIEPALLL KGDIMVKCYH KQFKAPERDV 360

VFRLQFHTCT IHGSQLWFGK DELDDACKDE RYPVDATVEF VFSSGPEKIK GGQEKAHPSS 420

SVWHLFSATH IYWFMLMSLY CDYTLHHEDS AEEDVSHTRG PLDGSLYAKV KKKRNPSAVA 480

TNGTPTSPGS EHSSRFMSIS SDSGHSSAMT DKQD 514

Nucleotide Sequence
(FASTA)

ATGATCAAGC CTGGAAAAAC AGACCCTCAC AGCTTTAAGG AGAAAGCGTT TAAGAAGAAG 60

AAGCCGTGTG CTGGATGCAA ACAGCCGGTC GAGGGGCAGG GCGTCACCTG TCGAGTTTGT 120

AAGGTGATAT GTCACAAGAA GTGCGAATCT AAGATACCTC CGGCCTGTCA GCCTCCTCCC 180

GTCACTGAAC TGCAGAGACG CGGCACTGCT CCTGCCCGCC ACATCCAGCA CTTGGGGTCA 240

ACAAAGTCCC TGAATACCAC CAAGCAAAGA AGCACCTTGC CGAGGAGCTT TAGCGTGGAT 300

CGTGTGATGG AGCGAAACTA TGACTTTGAC CTGACGTACA TCACTGAGCG CATCATCTCA 360

GTCTTCTTCC CGCCAGCCCT GGAAGAGCAA CGTTACCGTG GCAACTTGAA GGAGGTGGCG 420

CAGATGCTGA AGTCCAAACA CGATGACAAG TATCTGCTTT TCAACCTGTC AGAGAAACGC 480

CATGACATCA GTAGACTGAA CCCCAAGGTT CACAATTTTG GCTGGCCGAA CCTTCACGCT 540

CCTCCATTGG ATAAAATCTG CGCCATCTGT AAATCTATGG AAACATGGCT GAACTCGGAC 600

CCTCAGCACG TGGTAGTCCT ACATTGTAAG GGTAATAAAG GGAAGACTGG AGTCATTGTT 660

GCGGCTTACA TGCACTACAG CAAGATCTCT GCCGGGGCTG ACCAGGCGTT GAGTACACTG 720

GCCATGAGGA AATTCTGTGA GGACAAAGTC TCTTCATCGT TGCAGCCTTC ACAGACCAGG 780

TATATTTATT ACTTTGGGGG GTTATTATCA GGAGCCATTA AAATGAACAG TAGCCCCCTG 840

TTTCTCCACC ACGTCCTGAT TCCCGCCATT CCAAACTTCG AACCCAGTGC AGCTGCAGGT 900

TACCACCCCT TCCTGAAGAT CTATCAGTCC ATGCAGCTTG TCTACACTTC AGGAATCTAT 960

AACATTCAAG GTGTTGTAAC TCGAAAGCTA TGCATCACAA TAGAACCAGC CCTACTCCTC 1020

AAAGGTGATA TCATGGTGAA GTGTTATCAT AAACAGTTCA AGGCTCCGGA GCGGGATGTG 1080

GTATTCCGAC TCCAGTTCCA TACCTGCACC ATCCATGGAT CACAACTCTG GTTTGGGAAA 1140

GATGAACTGG ATGATGCCTG CAAGGATGAA AGATACCCTG TGGACGCAAC AGTGGAGTTC 1200

GTCTTCTCCT CGGGGCCAGA AAAAATAAAA GGGGGGCAGG AGAAAGCACA CCCCTCTAGC 1260

TCAGTATGGC ATCTATTCAG TGCTACACAT ATATATTGGT TTATGTTGAT GAGCCTATAC 1320

TGTGACTATA CTCTCCATCA TGAAGACAGC GCTGAAGAAG ATGTTTCACA TACCCGTGGA 1380

CCTTTGGATG GCAGCTTGTA TGCCAAAGTC AAGAAGAAAA GGAATCCAAG CGCAGTTGCC 1440

ACGAATGGAA CTCCTACCAG TCCTGGCTCT GAGCACAGCA GTCGTTTCAT GTCTATTAGC 1500

AGTGATTCTG GCCACTCCTC TGCTATGACT GACAAACAGG AT 1542

Domain Profile

S: 1     rrltedgfdldltyvteriiavsfPaeareevyrnnlrevvrlldskhrnkyklynlcse  60

         +r++e+++d+dlty+terii+v fP   +e++yr+nl+ev+++l+skh +ky+l+nl se

Q: 100   DRVMERNYDFDLTYITERIISVFFPPALEEQRYRGNLKEVAQMLKSKHDDKYLLFNL-SE  158

         699******************************************************.**

S: 61    rrydltklnakvaefgiedlnaPaleklvsickeldeWlseddenvvvlhckggkgrlGv  120

         +r+d+++ln+kv++fg+++l+aP+l+k+++ick +++Wl+ d+++vvvlhckg+kg++Gv

Q: 159   KRHDISRLNPKVHNFGWPNLHAPPLDKICAICKSMETWLNSDPQHVVVLHCKGNKGKTGV  218

         ************************************************************

S: 121   ivcayllaseisakadealdtfgerrtredkvagvkqPsqrryvsyfsqllkg  173

         iv+ay+++s+isa+ad+al t+++r+++edkv++  qPsq ry++yf +ll+g

Q: 219   IVAAYMHYSKISAGADQALSTLAMRKFCEDKVSSSLQPSQTRYIYYFGGLLSG  271

         **************************************************986

Domain Sequence
(FASTA)

DRVMERNYDF DLTYITERII SVFFPPALEE QRYRGNLKEV AQMLKSKHDD KYLLFNLSEK 60

RHDISRLNPK VHNFGWPNLH APPLDKICAI CKSMETWLNS DPQHVVVLHC KGNKGKTGVI 120

VAAYMHYSKI SAGADQALST LAMRKFCEDK VSSSLQPSQT RYIYYFGGLL SG 172

Keyword

Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005622	; C:intracellular
GO:0046872	; F:metal ion binding
GO:0004725	; F:protein tyrosine phosphatase activity
GO:0035556	; P:intracellular signal transduction
GO:0035335	; P:peptidyl-tyrosine dephosphorylation

KEGG

InterPros

IPR008973	; C2_Ca/lipid-bd_dom_CaLB.
IPR014019	; Phosphatase_tensin-typ.
IPR002219	; Prot_Kinase_C-like_PE/DAG-bd.
IPR014020	; Tensin_phosphatase_C2-dom.
IPR000242	; Tyr_Pase_rcpt/non-rcpt.

Pfam

PF00130	; C1_1; 1.
PF10409	; PTEN_C2; 1.
PF00102	; Y_phosphatase; 1.

SMARTs

SM00109

; C1; 1.

Prosites

PS51182	; C2_TENSIN; 1.
PS51181	; PPASE_TENSIN; 1.
PS00479	; ZF_DAG_PE_1; 1.
PS50081	; ZF_DAG_PE_2; 1.

Prints

Created Date

20-Feb-2013