EKS-LAC-00066

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LAC-00066

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	372.6	1.3E-111	19	315	297

Status

Unreviewed

Ensembl Protein

ENSLACP00000019397

UniProt Accession

H3BBX6;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK9

Gene Synonyms/Alias

CDK9;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000017060	ENSLACP00000019397	ENSLACT00000019532

Organism

Latimeria chalumnae

Functional Description

Protein Length

372

Protein Sequence
(FASTA)

MAKYYEAVEF PFCDEVSKYE KLAKIGQGTF GEVFKAKHRQ TGKKVALKKV LMENEKEGFP 60

ITALREIKIL QLLKHENVVN LIEICRTKAT QYNRYKGSIF LVFDFCEHDL AGLLSNANVK 120

FTLAEIKKVM QMLLNGLYYI HRNKILHRDM KAANVLITRD GVLKLADFGL ARAFSLAKNS 180

QPNRYTNRVV TLWYRPPELL LGERDYGPPI DLWGSGCIMA EMWTRSPIMQ GNTEQHQLTL 240

ISQLCGSITP EIWPNVDKYE LYQKLELPKG QKRKVKDRLK AYVKDPYALD LIDKLLVLDP 300

AQRTDSDDAL NHDFFWSDPM PSDLKNMLST HNQSMFEYLA PPRRRGGHMP QQTTNQNRNP 360

AATNQTEFER VF 372

Nucleotide Sequence
(FASTA)

ATGGCCAAGT ACTATGAAGC TGTGGAATTT CCCTTCTGTG ATGAAGTTTC AAAATATGAG 60

AAGCTGGCAA AGATTGGCCA GGGCACCTTT GGGGAGGTTT TTAAAGCGAA ACACAGACAG 120

ACAGGCAAGA AAGTTGCCTT AAAGAAAGTC TTGATGGAAA ATGAGAAAGA AGGGTTTCCT 180

ATCACAGCTT TGAGGGAAAT AAAAATCCTT CAACTCCTCA AACATGAGAA TGTGGTGAAC 240

CTCATTGAAA TCTGCAGAAC TAAAGCGACC CAGTATAACC GGTATAAAGG CAGCATCTTT 300

CTGGTGTTTG ATTTCTGTGA ACATGACCTG GCTGGTTTGC TCAGTAATGC TAATGTGAAG 360

TTTACTCTAG CTGAGATAAA GAAAGTGATG CAGATGTTAC TCAATGGACT CTACTACATT 420

CACAGGAATA AGATTTTACA CCGTGATATG AAAGCTGCAA ATGTCCTGAT CACACGAGAT 480

GGTGTTTTGA AACTGGCTGA TTTTGGATTG GCAAGAGCCT TCAGCCTAGC AAAGAACAGT 540

CAACCCAACC GGTACACCAA CAGGGTAGTG ACACTGTGGT ACCGACCACC TGAACTATTG 600

CTGGGAGAGC GTGATTATGG ACCTCCCATT GACCTCTGGG GGTCAGGCTG TATCATGGCA 660

GAGATGTGGA CACGTAGCCC TATTATGCAA GGCAACACAG AACAGCATCA GTTGACGCTG 720

ATTAGCCAGC TTTGTGGATC CATTACTCCT GAGATTTGGC CAAATGTGGA CAAATATGAA 780

CTTTACCAAA AGCTGGAGCT GCCAAAGGGA CAGAAGCGGA AGGTGAAGGA TCGACTGAAG 840

GCCTATGTAA AGGACCCTTA TGCTTTAGAC CTAATTGACA AGCTGTTGGT TTTAGATCCG 900

GCTCAAAGAA CTGACAGTGA TGATGCATTA AACCATGACT TTTTCTGGTC TGACCCCATG 960

CCTTCGGATC TCAAGAATAT GCTTTCCACA CACAACCAAT CAATGTTTGA GTACCTGGCT 1020

CCACCCAGAA GAAGAGGAGG TCACATGCCA CAGCAGACAA CCAATCAGAA TAGGAATCCT 1080

GCTGCAACCA ATCAGACTGA ATTTGAAAGA GTGTTCTGA 1119

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         yekl+kig+Gt+g+v+kak+++tg++vAlKk+ +e+ekeg+pitalrEi++l+ lkh+n+

Q: 19    YEKLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHENV  78

         99**********************************************************

S: 61    vkLlevva.......kdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqllegl  113

         v+L+e++        + k +++Lvf+f+e+dL+ ll++ +  k++l+e+k+++++ll+gl

Q: 79    VNLIEICRtkatqynRYKGSIFLVFDFCEHDLAGLLSNANV-KFTLAEIKKVMQMLLNGL  137

         ********999998777899*********************.******************

S: 114   aylHsnkilHRDlKpqNlLiskegklklaDfGlaraf....ssplktytkevvTlwYraP  169

          y+H+nkilHRD+K++N+Li+++g+lklaDfGlaraf    +s+ ++yt++vvTlwYr+P

Q: 138   YYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFslakNSQPNRYTNRVVTLWYRPP  197

         *************************************7776555557*************

S: 170   elLlgakeYstavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevs  229

         elLlg+++Y+  +D+W+ gci+ae++tr+p++qg++e++ql+ i++l+g+++ ++wp+v

Q: 198   ELLLGERDYGPPIDLWGSGCIMAEMWTRSPIMQGNTEQHQLTLISQLCGSITPEIWPNVD  257

         ************************************************************

S: 230   klpeyk.ksfpkkkkkklkekvkklkek..aldllekllaldpkkRisakealqhkyf  284

         k++ y+  ++pk +k+k+k+++k++ ++  aldl++kll ldp++R+++++al+h++f

Q: 258   KYELYQkLELPKGQKRKVKDRLKAYVKDpyALDLIDKLLVLDPAQRTDSDDALNHDFF  315

         ******8899**9999******988766579*************************98

Domain Sequence
(FASTA)

YEKLAKIGQG TFGEVFKAKH RQTGKKVALK KVLMENEKEG FPITALREIK ILQLLKHENV 60

VNLIEICRTK ATQYNRYKGS IFLVFDFCEH DLAGLLSNAN VKFTLAEIKK VMQMLLNGLY 120

YIHRNKILHR DMKAANVLIT RDGVLKLADF GLARAFSLAK NSQPNRYTNR VVTLWYRPPE 180

LLLGERDYGP PIDLWGSGCI MAEMWTRSPI MQGNTEQHQL TLISQLCGSI TPEIWPNVDK 240

YELYQKLELP KGQKRKVKDR LKAYVKDPYA LDLIDKLLVL DPAQRTDSDD ALNHDFF 297

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013