EKS-LAC-00244

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LAC-00244

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/MAPKAPK	430.7	2.2E-129	49	309	261

Status

Unreviewed

Ensembl Protein

ENSLACP00000020194

UniProt Accession

H3BE73;

Protein Name

Protein Synonyms/Alias

Gene Name

MAPKAPK3

Gene Synonyms/Alias

MAPKAPK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000017749	ENSLACP00000020194	ENSLACT00000020334

Organism

Latimeria chalumnae

Functional Description

Protein Length

386

Protein Sequence
(FASTA)

MLHNGNAQEQ EQSQAAGHAN NLLSAGLLCP HQHPKPEIKR HAITEEYKVS SQVLGLGING 60

RVLECYNKKT GEKCALKLLH DSLKARREVE LHWRASGGPH IVQIMDVYEN MHHGKRCLLI 120

VMECMGGGEL FSRIQERGDQ AFTEREASEI MRDIGTAIHH LHAMNIAHRD VKPENLLYTS 180

KESNAILKLT DFGFAKETTL QNALQTPCYT PYYVAPEVLG PEKYDKSCDM WSLGVITYIL 240

LCGYPPFYSN TGQAISPGMK RRIRMGQYEF PNPEWSEVSE EAKQLISQLL KTDPTERMTI 300

AQFMNHPWIN QSMVVPPTPL HTTRVLQEDK DMWDEVKEEM TSALATMRVD YEQVKIKDLD 360

TSSNPLLNKR RKKQAAATSF AVCNNQ 386

Nucleotide Sequence
(FASTA)

ATGCTTCATA ATGGAAATGC CCAGGAGCAA GAGCAGAGCC AGGCAGCTGG GCACGCCAAC 60

AACTTGCTGA GTGCCGGGCT GCTTTGCCCC CACCAGCACC CCAAGCCGGA GATTAAGAGA 120

CATGCCATCA CGGAAGAGTA CAAAGTGTCC AGCCAGGTCT TGGGGCTGGG GATCAATGGA 180

AGGGTGTTGG AATGCTACAA CAAGAAAACG GGAGAGAAAT GTGCTCTGAA GCTCCTTCAT 240

GACAGCCTGA AAGCTCGTCG GGAGGTGGAG TTGCACTGGC GGGCATCAGG GGGCCCACAC 300

ATTGTCCAGA TCATGGATGT TTATGAAAAC ATGCATCATG GGAAGAGGTG CTTGCTCATT 360

GTCATGGAAT GTATGGGGGG TGGAGAACTC TTCAGCAGGA TCCAGGAGAG AGGAGACCAG 420

GCCTTCACTG AAAGAGAGGC TTCGGAAATA ATGAGGGACA TTGGGACAGC TATTCATCAC 480

CTTCACGCAA TGAACATTGC CCACAGAGAT GTCAAGCCAG AAAATCTCCT CTATACCTCA 540

AAAGAGTCAA ATGCTATTCT CAAGCTCACT GATTTTGGTT TTGCGAAAGA GACGACCCTA 600

CAGAATGCTC TGCAGACTCC TTGCTACACA CCATATTATG TGGCGCCTGA AGTACTGGGT 660

CCAGAGAAGT ATGACAAATC ATGTGACATG TGGTCCTTGG GTGTAATCAC CTACATACTG 720

CTGTGTGGTT ACCCGCCTTT TTACTCTAAC ACGGGGCAGG CAATCTCTCC TGGGATGAAG 780

AGGAGGATCC GGATGGGACA GTATGAGTTT CCTAACCCAG AGTGGTCAGA GGTCTCAGAG 840

GAAGCAAAAC AGTTGATTAG TCAGTTATTG AAGACAGACC CGACGGAGAG AATGACAATT 900

GCACAATTTA TGAATCACCC CTGGATTAAT CAATCCATGG TTGTACCCCC GACTCCCCTT 960

CATACAACTC GGGTCCTTCA AGAAGACAAA GACATGTGGG ATGAAGTCAA GGAGGAGATG 1020

ACCAGTGCTT TGGCTACCAT GCGAGTGGAC TATGAACAGG TTAAAATCAA AGACCTCGAC 1080

ACCTCTAGCA ATCCACTGCT GAACAAACGG CGCAAAAAGC AAGCGGCAGC AACATCATTT 1140

GCAGTCTGCA ACAACCAGTA A 1161

Domain Profile

S: 2     lteevlGeGisgkvlecvkkktgekyalkilkdrkkvrrevelhvqasghknivelidvf  61

         ++++vlG Gi+g+vlec++kktgek+alk+l+d+ k+rrevelh++asg ++iv+++dv+

Q: 49    VSSQVLGLGINGRVLECYNKKTGEKCALKLLHDSLKARREVELHWRASGGPHIVQIMDVY  108

         789*********************************************************

S: 62    ensfedekrlllvlekleGGellsriqer..kaftekeasevvkdiasalkflhskniah  119

         en+++++++ll+v+e++ GGel+sriqer  +afte+ease+++di++a+++lh +niah

Q: 109   ENMHHGKRCLLIVMECMGGGELFSRIQERgdQAFTEREASEIMRDIGTAIHHLHAMNIAH  168

         ******************************9*****************************

S: 120   rDlkpenlLyeskeknapvklcDfglaketeeeeelktpcltaeyvaPevleaekeeall  179

         rD+kpenlLy+ske+na++kl+Dfg+aket+ +++l+tpc+t++yvaPevl++ek

Q: 169   RDVKPENLLYTSKESNAILKLTDFGFAKETTLQNALQTPCYTPYYVAPEVLGPEK-----  223

         *******************************************************.....

S: 180   ydksCDlWslGvilyillcGypPfyskkgraiskklkeriqegkyefPeeeWsevseeak  239

         ydksCD+WslGvi yillcGypPfys++g+ais+++k+ri++g+yefP++eWsevseeak

Q: 224   YDKSCDMWSLGVITYILLCGYPPFYSNTGQAISPGMKRRIRMGQYEFPNPEWSEVSEEAK  283

         ************************************************************

S: 240   dlirklLkrdpkerltieevlnhpwv  265

         +li++lLk+dp+er+ti++++nhpw+

Q: 284   QLISQLLKTDPTERMTIAQFMNHPWI  309

         *************************8

Domain Sequence
(FASTA)

VSSQVLGLGI NGRVLECYNK KTGEKCALKL LHDSLKARRE VELHWRASGG PHIVQIMDVY 60

ENMHHGKRCL LIVMECMGGG ELFSRIQERG DQAFTEREAS EIMRDIGTAI HHLHAMNIAH 120

RDVKPENLLY TSKESNAILK LTDFGFAKET TLQNALQTPC YTPYYVAPEV LGPEKYDKSC 180

DMWSLGVITY ILLCGYPPFY SNTGQAISPG MKRRIRMGQY EFPNPEWSEV SEEAKQLISQ 240

LLKTDPTERM TIAQFMNHPW I 261

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013