EKS-LAC-00202

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LAC-00202

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/LISK	358.3	2.7E-107	311	576	266

Status

Unreviewed

Ensembl Protein

ENSLACP00000021280

UniProt Accession

H3BHA9;

Protein Name

Protein Synonyms/Alias

Gene Name

LIMK1

Gene Synonyms/Alias

LIMK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000018699	ENSLACP00000021280	ENSLACT00000021421

Organism

Latimeria chalumnae

Functional Description

Protein Length

613

Protein Sequence
(FASTA)

IFLSCVNHLV SFVSGARCCE CNTSLSRLYY EKDGQLYCKK DYWLRYGELC HGCSEQITKG 60

LIMVAGEQKY HPECFICLNC HVFIGDGDTY ALVERSKLYC GRCYYQMIVT PVIDQILPDS 120

PCSRIPHTVT LVSIPASANG KRGFSVAIDQ NCTSQVCGSE HNHTVRIKEV DSEHISPDMK 180

NSIHVGDRIL EINGTPIRNV SLDEIDLLIQ ETSRLLQLTL EHDPDEQISQ EALSSAGSLS 240

NLCSPLRTPV RTPSGDVSAV RQRSIMRSCS IDKSPSSSTA GSPGFNRKDI GRSESLRVVS 300

KSHRIFRPSD LIHGEVLGKG YFGQAIKVTH RETGEVMVLK ELIRFDEETQ KAFLKEVKVM 360

RCLDHPNVLK FIGVLYKDKR LNLITEYIMG GTLRDIIKKM DSSYSWCNRV SFARDIASGM 420

IYIYIYIYIY MYGPVHVCYV IQNKSVVVAD FGLARLMVDE KSQSERKLSP GNLQTLKKPD 480

RKKRYTVVGN PYWMAPEMIN GEKWEQYAGG RFQIIGRVNA DPDYLPRTMD FGLNVNVFLD 540

NYCPLHCPSS FFPIAVLCCD LDPEKRPPFV KLQHWLENLK LHLEIRMPLI SELEQLDRAF 600

WQNHSRTQSK PPE 613

Nucleotide Sequence
(FASTA)

ATTTTTCTCT CCTGTGTTAA TCACCTTGTC TCCTTTGTTT CTGGTGCTAG GTGCTGTGAA 60

TGCAACACTT CACTGTCCCG ACTCTACTAT GAGAAGGACG GCCAGCTGTA CTGTAAGAAG 120

GATTACTGGC TGAGGTACGG AGAACTGTGT CATGGCTGCT CTGAACAGAT AACCAAGGGC 180

CTGATTATGG TGGCCGGAGA GCAGAAGTAC CACCCAGAAT GTTTTATCTG CCTAAACTGC 240

CACGTCTTCA TTGGCGATGG AGACACGTAT GCGCTGGTAG AGCGCTCCAA ACTTTACTGC 300

GGACGCTGCT ACTACCAGAT GATTGTCACA CCTGTGATCG ATCAGATCCT CCCGGACTCG 360

CCATGTTCCA GGATCCCACA CACCGTCACG CTGGTGTCCA TCCCGGCGTC AGCCAACGGC 420

AAGCGTGGCT TCTCTGTGGC CATCGATCAG AACTGCACTT CCCAGGTCTG CGGCTCGGAG 480

CACAACCACA CTGTCCGTAT CAAGGAGGTT GATTCCGAGC ACATCAGCCC AGATATGAAG 540

AACTCCATCC ATGTTGGGGA CCGGATCCTA GAAATTAACG GGACGCCAAT CAGAAATGTC 600

TCGCTGGACG AGATTGACCT GCTGATTCAA GAAACAAGCC GACTGCTACA GTTGACCTTG 660

GAGCATGACC CTGACGAGCA GATTTCACAA GAGGCTCTCA GCAGTGCCGG CTCCCTCTCC 720

AACCTGTGCA GCCCGCTGAG AACGCCGGTC CGGACGCCAA GCGGGGACGT CAGCGCGGTG 780

CGCCAGAGAT CAATCATGAG GAGTTGCAGC ATTGACAAGT CTCCCAGCTC CAGCACAGCA 840

GGCTCTCCTG GCTTCAACAG GAAAGATATC GGACGGTCGG AGTCACTGCG CGTGGTCTCC 900

AAGAGTCACC GGATCTTCCG CCCCTCGGAC CTGATCCACG GAGAGGTGCT GGGGAAAGGT 960

TATTTCGGAC AGGCCATCAA GGTGACTCAC CGGGAGACGG GCGAGGTGAT GGTGCTGAAG 1020

GAGCTGATCC GGTTCGATGA AGAGACACAG AAGGCCTTCC TCAAAGAGGT TAAAGTAATG 1080

CGTTGCCTGG ACCATCCCAA TGTGTTGAAG TTCATTGGGG TCCTCTACAA GGACAAGAGG 1140

CTGAACCTCA TCACAGAGTA CATCATGGGC GGGACCCTTC GGGACATCAT TAAGAAGATG 1200

GACAGCTCTT ACTCCTGGTG TAACAGGGTC AGCTTCGCTA GGGACATAGC ATCCGGCATG 1260

ATATATATAT ATATATATAT ATATATATAT ATGTACGGGC CTGTCCATGT ATGTTATGTA 1320

ATACAGAACA AAAGTGTTGT GGTGGCTGAT TTCGGGCTGG CCCGCCTGAT GGTGGATGAG 1380

AAGAGCCAGT CGGAGAGAAA GCTGTCACCG GGCAACCTGC AGACGCTGAA GAAACCGGAC 1440

CGGAAGAAGC GGTACACAGT GGTGGGGAAC CCCTACTGGA TGGCCCCTGA GATGATCAAC 1500

GGTGAGAAAT GGGAGCAGTA CGCTGGGGGG AGGTTTCAGA TCATCGGCCG GGTGAACGCG 1560

GACCCCGACT ACCTGCCCAG GACAATGGAC TTTGGCCTGA ATGTCAATGT GTTCCTGGAC 1620

AATTACTGCC CGTTGCACTG TCCTTCCTCT TTCTTCCCCA TCGCCGTCCT GTGTTGTGAT 1680

CTGGACCCCG AAAAAAGGCC GCCGTTTGTG AAGCTGCAAC ACTGGCTGGA GAACCTGAAG 1740

CTACACCTGG AGATCCGAAT GCCCCTTATC TCAGAACTGG AACAGCTGGA CCGAGCCTTC 1800

TGGCAGAACC ACAGCCGGAC CCAGAGCAAA CCCCCAGAAT GA 1842

Domain Profile

S: 1     livgeklGkGffsevfkvthrasGevmvlkeliradeenrknllkevkllrklehpnvlk  60

         li+ge+lGkG+f++++kvthr++Gevmvlkelir+dee++k++lkevk++r+l+hpnvlk

Q: 311   LIHGEVLGKGYFGQAIKVTHRETGEVMVLKELIRFDEETQKAFLKEVKVMRCLDHPNVLK  370

         689*********************************************************

S: 61    fiGvlvkdkklhllteyiegGtlkellkskes.lpwtqrvrlakdiasGlsylhskgiih  119

         fiGvl+kdk+l+l+teyi gGtl++++k+++s ++w  rv++a+diasG+ y++    i+

Q: 371   FIGVLYKDKRLNLITEYIMGGTLRDIIKKMDSsYSWCNRVSFARDIASGMIYIYIYIYIY  430

         *******************************99***************************

S: 120   rdlnsknclvredksvvvadfGlarlvveerkks......eklrslkkkdrkkrltvvGs  173

              + c v ++ksvvvadfGlarl+v+e+ +s       +l++lkk drkkr+tvvG+

Q: 431   MYGPVHVCYVIQNKSVVVADFGLARLMVDEKSQSerklspGNLQTLKKPDRKKRYTVVGN  490

         *********************************9899998999*****************

S: 174   PywmaPevlkgksydekvdvfsfGivlceiiarveadPdylPrtedfgldvkafreklva  233

         PywmaPe+++g+++++ +     G    +ii+rv+adPdylPrt+dfgl+v+ f +++++

Q: 491   PYWMAPEMINGEKWEQYA----GG--RFQIIGRVNADPDYLPRTMDFGLNVNVFLDNYCP  544

         ***********9999854....45..4579******************************

S: 234   edcPeaflklavvccdldpesrpsfeelekkl  265

          +cP++f+++av ccdldpe+rp+f++l+++l

Q: 545   LHCPSSFFPIAVLCCDLDPEKRPPFVKLQHWL  576

         *****************************997

Domain Sequence
(FASTA)

LIHGEVLGKG YFGQAIKVTH RETGEVMVLK ELIRFDEETQ KAFLKEVKVM RCLDHPNVLK 60

FIGVLYKDKR LNLITEYIMG GTLRDIIKKM DSSYSWCNRV SFARDIASGM IYIYIYIYIY 120

MYGPVHVCYV IQNKSVVVAD FGLARLMVDE KSQSERKLSP GNLQTLKKPD RKKRYTVVGN 180

PYWMAPEMIN GEKWEQYAGG RFQIIGRVNA DPDYLPRTMD FGLNVNVFLD NYCPLHCPSS 240

FFPIAVLCCD LDPEKRPPFV KLQHWL 266

Keyword

ATP-binding; Complete proteome; LIM domain; Metal-binding; Nucleotide-binding; Reference proteome; Zinc.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>