EPS-LOA-00056

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-LOA-00056

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/PTEN	276.5	1.6E-82	7	177	171

Status

Unreviewed

Ensembl Protein

ENSLAFP00000020804

UniProt Accession

G3SLZ9;

Protein Name

Protein Synonyms/Alias

Gene Name

TNS1

Gene Synonyms/Alias

TNS1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLAFG00000000579	ENSLAFP00000000487	ENSLAFT00000000581
ENSLAFG00000000579	ENSLAFP00000020804	ENSLAFT00000036957
ENSLAFG00000000579	ENSLAFP00000025371	ENSLAFT00000036138

Organism

Loxodonta africana

Functional Description

Protein Length

1298

Protein Sequence
(FASTA)

RSMSVSQTME DSCELDLVYI TERIIAVSFP STANEENFRS NLREVAQMLK SKHGGNYLLF 60

NLSERRPDIT KLHAKVLEFG WPDLHTPALE KICGVCKAMD TWLNADPHNV VVLHNKGNRG 120

RIGVVIAAYM HYSNISASAD QALDRFAMKR FYEDKIVPIG QPSQRRYVHY FSGLLSGSIK 180

MNNKPLFLHH VIMHGIPNFE SKGGCRPFLR IYQAMQPVYT SGIYNVQGDS QTSICITIEP 240

GLLLKGDILL KCYHKKFRSP ARDVIFRVQF HTCAIHDLGI VFGKEDLDDA FKDDRFPEYG 300

KVEFVFSYGP EKIQGINPGM EHLENGPSVS VDYNTSDPLI RWDSYDNFSG HREDGMEGRW 360

AVTRGDPASA PSMSVLSVPG QTFPETSPET KGQGLLSTSV TPGYASGVTT PHQNQICAPP 420

PPQIPRKEVL SRLFGGCPWA SVGKGSGQDQ RHLSDDAGPP GGGGLCCQRW ERLRPGLEFR 480

ASCREGRRRP PGDDGGFGEP EGAPEMLRMP SLFGGRSVHP LVFVPPEEDE GKVVSKLSEG 540

KFPATPESRK FLPGVFSPLP LAFAFMTLTF DPQSGPGLCS CESAITQKAL PTPASQGCRI 600

RSPERKAIWG WGGQEGAPVV HPVTDDSTEM PLLLPESCGL RQRPKPSGPM GQVVLGDAGG 660

QNLGYYVPLD GAAGHAFICA KDTYVSMGAV PLMLVSGGTL KPRSYVESVA RTAVAGPRAQ 720

EPETQSFSAP AAQANGHETP LRNGALGGSF VSPSPLSTSS PILSADRAGG NSGASGRTRR 780

MSCSDGSRES SDQGPRTPTQ PLLDSGFRSS SLGQPSPSAQ RSYQSSSPLP TVGSSYSSPD 840

YSLQQFNSSP ESQARPQFSV AGVHTVPGSP QARHRTVGTN TPPSPGFGRR ATNPSMAAPS 900

SPSLSHRQVT GPHGNTGTGF HAMWRPLPGA LAWAGTLEPT KAPSTPSFPV SPAYYPGLSS 960

PATSPSPDSA AFRQGSPTPA LPEKRRMKGS YPTPHCPCPP ETQISEHNSP ETRAKVKFVQ 1020

DTSKYWYKPE ISREQAIALL KDQEPGAFII RDSHSFRGAY GLAMKVSSPP PTIMQQNKKG 1080

RDMTHELVRH FLIETGPRGV KLKGCPNEPN FGSLSALVYQ HSIIPLALPC KLVIPNRDPT 1140

DESKDSSGSA NSTTDLLKQG AACNVLFVNS VDMESLTGPQ AISKATSETL AADPTPAATI 1200

VHFKVSAQGI TLTDNQRKLF FRRHYPLNTV TFCALDPQER NWFNLEGAPA KLFGFVARKQ 1260

GSTTDNACHL FAELDPNQPA SAIVNFVSKV MQSAGQKR 1298

Nucleotide Sequence
(FASTA)

AGAAGCATGA GTGTGAGCCA GACCATGGAG GACAGCTGTG AGCTGGACCT GGTGTACATC 60

ACGGAGAGGA TCATTGCCGT CTCCTTCCCC AGCACAGCCA ACGAGGAGAA CTTCCGGAGC 120

AACCTCCGCG AGGTGGCCCA AATGCTCAAG TCCAAACATG GAGGCAACTA CCTGCTTTTC 180

AACCTCTCTG AGCGGAGACC TGACATTACA AAGCTCCACG CCAAGGTGCT GGAATTCGGC 240

TGGCCTGACT TACACACCCC CGCCCTGGAG AAGATCTGCG GTGTCTGCAA GGCCATGGAC 300

ACCTGGCTCA ACGCTGATCC CCACAATGTC GTCGTGCTAC ACAACAAGGG AAACCGAGGC 360

AGGATAGGTG TGGTCATCGC GGCTTACATG CATTACAGCA ACATTTCTGC CAGTGCTGAC 420

CAGGCTCTGG ACCGGTTTGC AATGAAACGG TTCTATGAGG ATAAGATTGT TCCCATTGGT 480

CAACCATCCC AGAGAAGGTA TGTGCATTAC TTCAGCGGCC TCCTCTCTGG CTCCATCAAA 540

ATGAACAACA AGCCCTTGTT TCTGCACCAC GTGATCATGC ACGGCATCCC CAACTTTGAA 600

TCTAAAGGAG GCTGTCGGCC CTTTCTGCGG ATCTACCAGG CCATGCAACC TGTTTACACG 660

TCTGGCATCT ACAACGTTCA AGGAGACAGC CAGACAAGCA TCTGCATTAC CATCGAGCCT 720

GGGCTGCTCT TAAAGGGAGA CATCTTGCTG AAGTGCTACC ACAAGAAGTT CCGAAGCCCA 780

GCACGTGATG TCATCTTCCG TGTGCAGTTC CACACCTGTG CCATCCATGA CTTGGGTATT 840

GTCTTCGGGA AGGAAGACCT TGATGATGCC TTCAAAGATG ATCGATTTCC AGAATATGGC 900

AAAGTGGAGT TTGTATTTTC TTACGGGCCA GAGAAAATTC AAGGTATAAA CCCAGGCATG 960

GAGCACCTGG AGAACGGGCC AAGTGTGTCT GTGGACTACA ACACCTCCGA CCCCCTCATC 1020

CGCTGGGACT CCTACGACAA CTTCAGTGGG CATCGAGAGG ATGGCATGGA GGGTAGATGG 1080

GCAGTTACCA GGGGAGACCC TGCCTCTGCC CCCTCCATGA GCGTCCTTAG TGTTCCAGGA 1140

CAAACCTTCC CGGAAACAAG CCCTGAGACC AAGGGGCAGG GGCTGCTTTC CACTTCGGTA 1200

ACACCTGGTT ACGCTAGTGG TGTCACCACA CCACATCAAA ACCAGATATG CGCCCCCCCG 1260

CCCCCCCAAA TCCCCAGGAA GGAAGTCCTT TCCAGACTAT TTGGGGGCTG TCCCTGGGCT 1320

AGTGTTGGAA AGGGGTCAGG TCAAGACCAA AGACACCTCA GTGATGATGC AGGACCACCT 1380

GGAGGGGGTG GCCTTTGCTG CCAGCGCTGG GAGAGACTGA GGCCCGGGTT GGAATTTAGG 1440

GCCAGCTGCA GGGAGGGAAG GAGACGCCCT CCTGGGGATG ATGGTGGGTT TGGAGAACCA 1500

GAAGGGGCTC CTGAAATGTT AAGGATGCCT TCACTCTTTG GAGGTCGTTC TGTCCATCCC 1560

CTTGTCTTTG TTCCCCCAGA GGAAGATGAG GGGAAGGTGG TGTCCAAGCT GTCTGAAGGT 1620

AAGTTTCCTG CCACCCCAGA AAGTAGGAAG TTTCTGCCTG GTGTCTTCAG CCCACTCCCA 1680

CTTGCTTTTG CATTTATGAC CTTGACATTT GACCCTCAAA GTGGGCCTGG CCTATGCTCC 1740

TGTGAATCTG CCATCACCCA GAAGGCTTTG CCTACTCCAG CCAGCCAGGG TTGCAGAATA 1800

AGAAGTCCTG AGAGGAAGGC GATTTGGGGC TGGGGGGGGC AGGAAGGGGC CCCTGTGGTG 1860

CACCCTGTCA CAGATGACTC AACTGAGATG CCTTTGCTTC TCCCTGAGAG CTGTGGTCTT 1920

AGGCAAAGGC CAAAGCCATC TGGACCCATG GGACAAGTGG TTCTGGGTGA TGCAGGTGGG 1980

CAAAATCTTG GTTATTATGT GCCTCTGGAT GGGGCTGCAG GTCATGCATT CATTTGTGCG 2040

AAAGACACAT ACGTTTCTAT GGGAGCAGTT CCCCTGATGC TGGTCTCGGG AGGAACGCTA 2100

AAGCCCCGGA GCTATGTCGA GTCTGTGGCG CGGACAGCCG TGGCTGGGCC CCGAGCCCAG 2160

GAGCCTGAGA CTCAAAGTTT TAGCGCCCCA GCTGCCCAAG CCAATGGCCA CGAGACACCC 2220

CTGAGGAACG GGGCACTGGG CGGCTCCTTT GTCTCTCCCA GCCCCCTCTC CACCAGCAGC 2280

CCCATCCTCA GCGCTGACAG GGCTGGAGGT AATAGTGGTG CGTCTGGCAG GACCAGAAGG 2340

ATGTCTTGCT CTGATGGTTC TAGGGAGAGC AGTGACCAGG GCCCTCGAAC ACCCACCCAG 2400

CCATTGTTGG ATTCTGGCTT CCGCTCCAGC AGCCTGGGGC AGCCCAGTCC TTCAGCCCAG 2460

AGAAGCTACC AGAGCTCCTC TCCTCTCCCG ACCGTGGGGA GCAGCTACAG CAGCCCGGAC 2520

TACTCTCTCC AGCAGTTCAA CTCGTCTCCA GAAAGCCAGG CCCGGCCTCA GTTCAGTGTG 2580

GCTGGCGTCC ACACGGTGCC TGGGAGCCCG CAGGCACGCC ACAGGACAGT GGGCACCAAC 2640

ACTCCCCCTA GTCCTGGCTT TGGCCGGCGG GCCACCAACC CCAGCATGGC TGCCCCCAGC 2700

AGTCCCAGTT TAAGCCACCG CCAAGTGACG GGTCCCCATG GGAACACAGG AACTGGTTTC 2760

CATGCAATGT GGCGACCACT CCCGGGAGCC CTGGCCTGGG CCGGCACCTT GGAGCCCACC 2820

AAGGCTCCCT CCACGCCTTC CTTCCCTGTC TCCCCTGCCT ACTACCCTGG CCTGAGCAGC 2880

CCTGCCACCT CCCCATCACC GGATTCAGCA GCCTTCCGGC AAGGGAGCCC AACACCAGCC 2940

TTGCCAGAGA AGCGGAGGAT GAAAGGGAGC TACCCTACCC CTCATTGTCC TTGCCCTCCA 3000

GAGACACAGA TCTCAGAACA CAACAGCCCC GAGACGCGGG CTAAAGTGAA GTTTGTCCAG 3060

GACACTTCCA AGTATTGGTA CAAGCCTGAG ATCTCACGAG AACAGGCCAT TGCACTCCTT 3120

AAGGACCAGG AGCCAGGGGC CTTTATCATC CGTGACAGCC ACTCCTTCAG AGGAGCCTAT 3180

GGGCTGGCCA TGAAAGTGTC TTCTCCCCCT CCAACCATCA TGCAGCAGAA TAAAAAAGGT 3240

AGAGACATGA CCCATGAGCT GGTGAGGCAT TTCCTGATAG AGACCGGTCC CAGAGGAGTC 3300

AAGCTCAAGG GATGTCCCAA TGAGCCAAAC TTCGGTTCTC TATCTGCCCT GGTCTACCAG 3360

CACTCCATCA TCCCATTGGC TCTGCCCTGT AAGCTGGTCA TTCCAAACCG AGACCCCACA 3420

GATGAATCAA AAGATAGCTC AGGCTCTGCC AACTCAACCA CCGATCTGCT GAAGCAAGGG 3480

GCAGCCTGCA ATGTGCTGTT CGTCAACTCT GTGGACATGG AGTCACTCAC TGGGCCACAG 3540

GCCATCTCCA AAGCCACATC TGAGACATTG GCTGCTGACC CCACACCAGC TGCCACCATT 3600

GTTCACTTCA AAGTCTCCGC CCAGGGAATC ACACTGACTG ACAACCAGAG AAAGCTCTTC 3660

TTCAGACGAC ACTATCCCCT CAACACTGTC ACTTTCTGTG CCCTGGATCC ACAGGAAAGA 3720

AATTGGTTCA ACTTGGAGGG TGCCCCTGCA AAGCTCTTCG GCTTTGTGGC GCGGAAGCAG 3780

GGCAGCACCA CAGACAATGC CTGCCACCTC TTCGCTGAGC TTGACCCCAA CCAGCCTGCC 3840

TCTGCCATTG TCAACTTCGT CTCCAAGGTC ATGCAGAGCG CCGGCCAGAA GAGATGA 3897

Domain Profile

S: 2     rltedgfdldltyvteriiavsfPaeareevyrnnlrevvrlldskhrnkyklynlcser  61

         +++ed+++ldl+y+teriiavsfP++a+ee++r+nlrev+++l+skh ++y+l+nl ser

Q: 7     QTMEDSCELDLVYITERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL-SER  65

         689*****************************************************.***

S: 62    rydltklnakvaefgiedlnaPaleklvsickeldeWlseddenvvvlhckggkgrlGvi  121

         r d+tkl+akv efg++dl++Palek++ +ck++d+Wl++d++nvvvlh+kg++gr+Gv+

Q: 66    RPDITKLHAKVLEFGWPDLHTPALEKICGVCKAMDTWLNADPHNVVVLHNKGNRGRIGVV  125

         ************************************************************

S: 122   vcayllaseisakadealdtfgerrtredkvagvkqPsqrryvsyfsqllkg  173

         ++ay+++s+isa+ad+ald+f+++r++edk++++ qPsqrryv+yfs+ll+g

Q: 126   IAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSG  177

         *************************************************997

Domain Sequence
(FASTA)

QTMEDSCELD LVYITERIIA VSFPSTANEE NFRSNLREVA QMLKSKHGGN YLLFNLSERR 60

PDITKLHAKV LEFGWPDLHT PALEKICGVC KAMDTWLNAD PHNVVVLHNK GNRGRIGVVI 120

AAYMHYSNIS ASADQALDRF AMKRFYEDKI VPIGQPSQRR YVHYFSGLLS G 171

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0030055	; C:cell-substrate junction
GO:0007044	; P:cell-substrate junction assembly
GO:0010761	; P:fibroblast migration

KEGG

InterPros

IPR008973	; C2_Ca/lipid-bd_dom_CaLB.
IPR011993	; PH_like_dom.
IPR014019	; Phosphatase_tensin-typ.
IPR013625	; PTB.
IPR006020	; PTyr_interaction_dom.
IPR000980	; SH2.
IPR014020	; Tensin_phosphatase_C2-dom.

Pfam

PF08416	; PTB; 1.
PF10409	; PTEN_C2; 1.
PF00017	; SH2; 1.

SMARTs

SM00462	; PTB; 1.
SM00252	; SH2; 1.

Prosites

PS51182	; C2_TENSIN; 1.
PS51181	; PPASE_TENSIN; 1.
PS50001	; SH2; 1.

Prints

Created Date

20-Feb-2013