EPS-LOA-00014

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-LOA-00014

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	67.7	1.2E-18	106	200	95

Status

Unreviewed

Ensembl Protein

ENSLAFP00000027399

UniProt Accession

G3SNX9;

Protein Name

Protein Synonyms/Alias

Gene Name

DUSP11

Gene Synonyms/Alias

DUSP11;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLAFG00000001637	ENSLAFP00000027399	ENSLAFT00000036589
ENSLAFG00000001637	ENSLAFP00000001364	ENSLAFT00000001636

Organism

Loxodonta africana

Functional Description

Protein Length

327

Protein Sequence
(FASTA)

MNHWHHARSD WGQGRAFSGQ SSSKKKGKNH IPERWKDYLP VGRRMPGTRF IAFKVPLKKS 60

FEGKLAPEEC FSPLDLFNKI QEQNEELGLI IDLTYTQRYY NPEDFPEAVP YLKIFTVGHQ 120

VPDDDTIFKF KHAVNGFLKE NKDNDKLIGV HCTHGLNRTG YLICRYLIDV EGMRPDDAIE 180

LFNRCRGHCI ERINYIEDLQ NGPVRKNWGS GVSRSSGFEE SAHFMGPVHT TKVFPGTSPY 240

HRGPGYNLHQ TQDYPTQSRH FHSQTQSVSF VLRKFSQNPY VYRRGLLPPP GPHGQDYSQR 300

RYSWNVKPDT SQASQNKRLP LIMEWHL 327

Nucleotide Sequence
(FASTA)

ATGAACCACT GGCATCATGC CCGCAGCGAC TGGGGCCAGG GACGGGCCTT TTCTGGACAG 60

TCCTCATCCA AAAAGAAGGG CAAAAACCAC ATCCCCGAAA GGTGGAAAGA CTACCTCCCA 120

GTTGGGCGGC GGATGCCTGG GACTCGTTTC ATTGCTTTCA AAGTTCCTTT GAAAAAGAGT 180

TTTGAAGGGA AACTTGCTCC AGAAGAATGT TTTTCCCCTT TGGATCTTTT TAACAAAATC 240

CAAGAACAAA ATGAAGAACT TGGACTGATT ATTGATTTAA CATATACTCA GCGTTATTAT 300

AACCCAGAGG ATTTCCCGGA AGCTGTTCCT TACTTAAAAA TATTTACAGT TGGACATCAG 360

GTTCCTGATG ATGACACTAT TTTTAAGTTC AAACATGCTG TTAATGGGTT TTTGAAAGAA 420

AATAAAGATA ATGACAAACT TATTGGGGTC CACTGTACCC ATGGTTTAAA CAGGACTGGC 480

TATCTCATCT GCAGATATTT GATTGATGTA GAAGGCATGA GGCCAGATGA TGCAATTGAA 540

TTATTCAATA GGTGCCGAGG ACATTGCATA GAAAGAATAA ACTACATTGA AGACCTTCAG 600

AATGGTCCTG TCAGAAAGAA TTGGGGTTCC GGCGTATCCA GGTCAAGTGG TTTTGAAGAA 660

TCAGCACATT TCATGGGACC AGTCCATACC ACCAAGGTAT TTCCTGGAAC CAGCCCGTAC 720

CACCGAGGAC CTGGGTATAA TCTACATCAG ACCCAAGATT ACCCAACGCA GTCTCGGCAT 780

TTCCATTCTC AGACCCAGTC AGTCAGTTTT GTTTTAAGGA AATTTTCACA AAATCCGTAT 840

GTTTACCGGA GAGGCCTTCT TCCACCTCCT GGTCCCCATG GGCAGGACTA TTCACAAAGG 900

AGATACTCTT GGAATGTAAA GCCAGACACC AGTCAAGCAT CCCAGAATAA AAGGTTGCCT 960

CTCATAATGG AATGGCACCT T 981

Domain Profile

S: 45    PeylikkgityknipvdDsdvtdllqyfdeaaefideakekggkvlvHCaaGvsRSatlv  104

         Pe++   +i  ++ +v D+d   ++++ ++++ f++e+k++++ + vHC++G++R+++l+

Q: 106   PEAVPYLKIFTVGHQVPDDD--TIFKFKHAVNGFLKENKDNDKLIGVHCTHGLNRTGYLI  163

         55554444444444555544..69************************************

S: 105   laYLmkveglslsdAieavkrkrpsiepnegfleQLl  141

         + YL++veg++ +dAie ++r+r++++++ +++e L

Q: 164   CRYLIDVEGMRPDDAIELFNRCRGHCIERINYIEDLQ  200

         *********************************9986

Domain Sequence
(FASTA)

PEAVPYLKIF TVGHQVPDDD TIFKFKHAVN GFLKENKDND KLIGVHCTHG LNRTGYLICR 60

YLIDVEGMRP DDAIELFNRC RGHCIERINY IEDLQ 95

Keyword

Complete proteome; Hydrolase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Taeniopygia guttata"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0004725	; F:protein tyrosine phosphatase activity
GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0035335	; P:peptidyl-tyrosine dephosphorylation

KEGG

InterPros

IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR000387	; Tyr/Dual-specificity_Pase.
IPR016130	; Tyr_Pase_AS.

Pfam

PF00782

; DSPc; 1.

SMARTs

Prosites

PS00383	; TYR_PHOSPHATASE_1; 1.
PS50056	; TYR_PHOSPHATASE_2; 1.

Prints

Created Date

20-Feb-2013