EKS-LOA-00435

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LOA-00435

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/WEE	315.8	2.5E-94	101	349	249

Status

Unreviewed

Ensembl Protein

ENSLAFP00000001884

UniProt Accession

G3SQ41;

Protein Name

Protein Synonyms/Alias

Gene Name

PKMYT1

Gene Synonyms/Alias

PKMYT1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLAFG00000002254	ENSLAFP00000001884	ENSLAFT00000002254

Organism

Loxodonta africana

Functional Description

Protein Length

497

Protein Sequence
(FASTA)

MPMPTKGTLP PLCGTPAPVP AYFRHAEPGF SFKRPRGLSR SLPPRPPAKG SIPISRLFPS 60

RTPGWHQPQP RKVSFWGEAS ETLQSSGYNP SRPESFFQQC FQRLGLLGHG SYGEVFKVRS 120

KEDGRLYAIK RSVLPFRGPK DRARKLAEVG SHEKVGRHPR CVRLERAWEE GGLLYLQMEL 180

CGPSLQQHCE AKGTGLPEAQ VWGYLRDTLL ALAHLHSRGL VHLDIKPANI FLGPWDRCKL 240

GDFGLLVELG AAGACEAQEG DPRYMAPELL QGSYGTAADV FSLGLTILEV ACNMELPHGG 300

EGWQQLRQGY LPPEFTAGLS AELHGVLAMM LEPDPTLRAT AEALLALPML RQPRPWSVLW 360

YMAAEALSRG WALWQALLAL LCWLCHRLAH PASWLQPRGP PATPPGSPPC SFLLDSSLSS 420

NWEDDSFRPS LSPEAVLART AGSTSTPHSG SPAPWSRYTL RDPLDLSDID SAPSLGSFPS 480

FEPRNLLSLF EDSLDST 497

Nucleotide Sequence
(FASTA)

null 4

Domain Profile

S: 1     FeevekiGkGefgevfkvvkredgklyAikkskkplkglskekkalrEvtahavlgqhen  60

         F+++  +G+G++gevfkv+++edg+lyAik+s  p++g ++++++l+Ev +h+++g+h+

Q: 101   FQRLGLLGHGSYGEVFKVRSKEDGRLYAIKRSVLPFRGPKDRARKLAEVGSHEKVGRHPR  160

         889999******************************************************

S: 61    vvryisaWeeddslyiqtElCeggsLeaalqeceakkkaleeaelkkilldlllglrylH  120

         +vr+ +aWee + ly+q+ElC g sL+++   ceak + l+ea+++ +l d ll+l +lH

Q: 161   CVRLERAWEEGGLLYLQMELC-GPSLQQH---CEAKGTGLPEAQVWGYLRDTLLALAHLH  216

         *********************.*******...****************************

S: 121   ssslvHlDikpenifitkevtlklgDlGlvtelnsedkskveEGDsrylakEilqeeysk  180

         s+ lvHlDikp+nif+    ++klgD+Gl++el+++ + +++EGD ry+a+E+lq++y +

Q: 217   SRGLVHLDIKPANIFLGPWDRCKLGDFGLLVELGAAGACEAQEGDPRYMAPELLQGSYGT  276

         ************************************************************

S: 181   lkaDiFslgltilevaanvelPsnGeaWhklRkgklpdeilkelsedlrellklmlepdp  240

         + aD+Fslgltileva+n+elP+ Ge W++lR+g+lp+e+++ ls +l+ +l++mlepdp

Q: 277   A-ADVFSLGLTILEVACNMELPHGGEGWQQLRQGYLPPEFTAGLSAELHGVLAMMLEPDP  335

         *.**********************************************************

S: 241   erRptaeellkhev  254

         + R+tae+ll+ ++

Q: 336   TLRATAEALLALPM  349

         **********9876

Domain Sequence
(FASTA)

FQRLGLLGHG SYGEVFKVRS KEDGRLYAIK RSVLPFRGPK DRARKLAEVG SHEKVGRHPR 60

CVRLERAWEE GGLLYLQMEL CGPSLQQHCE AKGTGLPEAQ VWGYLRDTLL ALAHLHSRGL 120

VHLDIKPANI FLGPWDRCKL GDFGLLVELG AAGACEAQEG DPRYMAPELL QGSYGTAADV 180

FSLGLTILEV ACNMELPHGG EGWQQLRQGY LPPEFTAGLS AELHGVLAMM LEPDPTLRAT 240

AEALLALPM 249

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0010923	; P:negative regulation of phosphatase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013