EPS-LOA-00024

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-LOA-00024

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	193.1	9.2E-57	2	217	216

Status

Unreviewed

Ensembl Protein

ENSLAFP00000002414

UniProt Accession

G3SRB6;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1L

Gene Synonyms/Alias

PPM1L;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLAFG00000002887	ENSLAFP00000002414	ENSLAFT00000002887

Organism

Loxodonta africana

Functional Description

Protein Length

228

Protein Sequence
(FASTA)

QTAAEYVKSR LPEALKQHLQ EYEKDKENSA LSYQTILEQQ ILSIDREMLE KLTVSYDEAG 60

TTCLIALLSD KDLTVANVGD SRGVLCDKDG NAIPLSHDHK PYQLKERKRI KRAGGFISFN 120

GSWRVQGILA MSRSLGDYPL KNLNVVIPDP DILTFDLDKL QPEFMILASD GLWDAFSNEE 180

AVRFIKERLD EPHFGAKSIV LQSFYRGCPD NITVMVVKFR NSGKTEEQ 228

Nucleotide Sequence
(FASTA)

CAGACTGCAG CTGAATATGT AAAATCTCGA CTCCCAGAGG CCCTGAAACA GCATCTTCAG 60

GAATATGAGA AAGACAAAGA GAACAGTGCA CTGTCTTACC AGACCATCCT TGAACAGCAG 120

ATCCTGTCAA TTGACCGAGA AATGCTGGAG AAGTTGACTG TGTCCTATGA TGAAGCAGGC 180

ACAACATGTT TGATTGCTCT GCTATCAGAT AAAGACCTCA CTGTGGCCAA TGTCGGCGAC 240

TCACGTGGCG TCCTGTGTGA CAAGGACGGG AATGCCATTC CTTTGTCTCA TGACCACAAG 300

CCTTACCAAC TGAAGGAAAG AAAGAGAATA AAGAGAGCTG GTGGTTTCAT CAGTTTTAAT 360

GGTTCCTGGA GGGTCCAGGG CATCCTGGCC ATGTCTCGGT CCCTGGGGGA TTATCCACTC 420

AAAAATCTCA ACGTGGTCAT CCCTGACCCA GATATCCTGA CCTTTGACCT GGACAAGCTC 480

CAGCCCGAGT TCATGATCTT GGCATCAGAT GGCCTCTGGG ATGCTTTCAG CAATGAAGAA 540

GCTGTTCGAT TCATCAAGGA GCGCTTGGAT GAACCTCACT TTGGGGCCAA GAGCATAGTT 600

TTACAGTCAT TTTACAGAGG CTGCCCTGAC AATATAACAG TCATGGTAGT GAAGTTCAGG 660

AATAGCGGCA AAACAGAAGA GCAGTGA 687

Domain Profile

S: 48    evakfcseklheilaeele....sseseerkvk....kalakaFlstdeelkvleeksld  99

         ++a++++++l e+l++ l+    ++e++         ++l++  ls+d+e+  le+ + +

Q: 2     TAAEYVKSRLPEALKQHLQeyekDKENS----AlsyqTILEQQILSIDREM--LEKLTVS  55

         7899999999999999999553333333....234559*************..999999*

S: 100   idksGstavvalikdsklyvanvGdSravLcr.ngkavelssdHkpsredEleRieeagg  158

          d+ G+t+++al++d++l+vanvGdSr vLc+ +g+a++ls dHkp + +E++Ri++agg

Q: 56    YDEAGTTCLIALLSDKDLTVANVGDSRGVLCDkDGNAIPLSHDHKPYQLKERKRIKRAGG  115

         ********************************566************************9

S: 159   svilkdga.RvlGvLavsRalGdlylk..pyvtpePevtshrltsede.fliLasDGlwd  214

          +  + g  Rv+G La+sR+lGd+ lk   +v+p+P++  ++l++ +  f+iLasDGlwd

Q: 116   FISFN-GSwRVQGILAMSRSLGDYPLKnlNVVIPDPDILTFDLDKLQPeFMILASDGLWD  174

         99977.667******************8889************765544***********

S: 215   vvsneeavslvrdvlekkeaeqeaakkLvklalargskdnvsaivv  260

          +sneeav++++++l+   ++   ak++v ++  rg+ dn++++vv

Q: 175   AFSNEEAVRFIKERLD---EPHFGAKSIVLQSFYRGCPDNITVMVV  217

         ****************...999********************9997

Domain Sequence
(FASTA)

TAAEYVKSRL PEALKQHLQE YEKDKENSAL SYQTILEQQI LSIDREMLEK LTVSYDEAGT 60

TCLIALLSDK DLTVANVGDS RGVLCDKDGN AIPLSHDHKP YQLKERKRIK RAGGFISFNG 120

SWRVQGILAM SRSLGDYPLK NLNVVIPDPD ILTFDLDKLQ PEFMILASDG LWDAFSNEEA 180

VRFIKERLDE PHFGAKSIVL QSFYRGCPDN ITVMVV 216

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0000165	; P:MAPK cascade
GO:0008152	; P:metabolic process
GO:0007178	; P:transmembrane receptor protein serine/threonine kinase signaling pathway

KEGG

InterPros

IPR001932	; PP2C-like.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481

; PP2C; 1.

SMARTs

SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

Prints

Created Date

20-Feb-2013