EKS-LOA-00227

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LOA-00227

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE7	337.8	5.6E-101	98	341	244

Status

Unreviewed

Ensembl Protein

ENSLAFP00000004194

UniProt Accession

G3SVD1;

Protein Name

Protein Synonyms/Alias

Gene Name

MAP2K7

Gene Synonyms/Alias

MAP2K7;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLAFG00000005010	ENSLAFP00000004194	ENSLAFT00000005011

Organism

Loxodonta africana

Functional Description

Protein Length

497

Protein Sequence
(FASTA)

PHPVIVITLS PAPAPSQRAA LQLPLANDGG NRSPSSESSP QHPTPPVRPR HMLGLPSALY 60

TPRSMESIEI DQKLQEIMKQ TGYLTIGGQR YQAEINDLEN LGEMGSGTCG QVWKMCFRKT 120

GHIIAVKQMR RSGNKEENKR ILMDLDVVLK SHDCPYIVQC FGTFITNTDV FIAMELMGTC 180

AEKLKKRMQG PIPERILGKM TVAIVKALFY LKEKHGVIHR DVKPSNILLD ERGQIKLCDF 240

GISGRLVDSK AKTRSAGCAA YMAPERIDPP DPTKPDYDIR ADVWSLGISL VELATGQFPY 300

KNCKTDFEVL TKVLQEEPPL LPGHMGFSGD FQSFVKDCLT PGQPPERPPD RHCERKTAGH 360

AQTCLFIYCT WWGVWGQGEE ALRGSVSSLV YATLSPTSTP VPGSAWALAA PASLQPGAVG 420

RGGRLPASRG AARGTRWRPC SPGGPGPSLP ALGPGPASLL SDTVLTPCPG PRPGAAAGRL 480

SRRCLGRLPA TTAPRCR 497

Nucleotide Sequence
(FASTA)

null 4

Domain Profile

S: 1     lekleelGaGnggvVekvlhkksgkilavKtirleikkeeqkqilrelevlkkssnspyi  60

         le+l+e+G+G++g+V+k+ ++k+g+i+avK++r++ +kee+k+il++l+v+ ks+++pyi

Q: 98    LENLGEMGSGTCGQVWKMCFRKTGHIIAVKQMRRSGNKEENKRILMDLDVVLKSHDCPYI  157

         7899********************************************************

S: 61    vkfyGafvsegdvsicmelmdgtsldkvlkkvlekkkripekvlgkiavavvkaleylke  120

         v+++G+f++++dv+i+melm  t+ +k+ k++   ++ ipe++lgk++va+vkal ylke

Q: 158   VQCFGTFITNTDVFIAMELMG-TCAEKLKKRM---QGPIPERILGKMTVAIVKALFYLKE  213

         *********************.*****99996...9************************

S: 121   klkiiHRDvKPsNiLvnskGevKlCDFGvsgqlvdsiAksa.vGtksYmaPErieg....  175

         k+ +iHRDvKPsNiL++++G++KlCDFG+sg+lvds Ak++ +G+++YmaPEri++

Q: 214   KHGVIHRDVKPSNILLDERGQIKLCDFGISGRLVDSKAKTRsAGCAAYMAPERIDPpdpt  273

         *******************************************************99999

S: 176   kkkYsvksdvWslGltlvelatgrypyeklkeilellkaivneeppklpee.efseefqe  234

         k++Y++++dvWslG++lvelatg++py+++k+++e+l+++++eepp lp +  fs +fq+

Q: 274   KPDYDIRADVWSLGISLVELATGQFPYKNCKTDFEVLTKVLQEEPPLLPGHmGFSGDFQS  333

         9************************************************9999*******

S: 235   fvskClkk  242

         fv++Cl+

Q: 334   FVKDCLTP  341

         ******84

Domain Sequence
(FASTA)

LENLGEMGSG TCGQVWKMCF RKTGHIIAVK QMRRSGNKEE NKRILMDLDV VLKSHDCPYI 60

VQCFGTFITN TDVFIAMELM GTCAEKLKKR MQGPIPERIL GKMTVAIVKA LFYLKEKHGV 120

IHRDVKPSNI LLDERGQIKL CDFGISGRLV DSKAKTRSAG CAAYMAPERI DPPDPTKPDY 180

DIRADVWSLG ISLVELATGQ FPYKNCKTDF EVLTKVLQEE PPLLPGHMGF SGDFQSFVKD 240

CLTP 244

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0000287	; F:magnesium ion binding
GO:0004708	; F:MAP kinase kinase activity
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007257	; P:activation of JUN kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013