EKS-LOA-00321

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LOA-00321

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	353.9	6.7E-106	12	262	251

Status

Unreviewed

Ensembl Protein

ENSLAFP00000004395

UniProt Accession

G3SVV1;

Protein Name

Protein Synonyms/Alias

Gene Name

STK24

Gene Synonyms/Alias

STK24;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLAFG00000005249	ENSLAFP00000004395	ENSLAFT00000005249

Organism

Loxodonta africana

Functional Description

Protein Length

419

Protein Sequence
(FASTA)

LQNLKADPEE LFTKLEKIGK GSFGEVFKGI DNRTQKVVAI KIIDLEEAED EIEDIQQEIT 60

VLSQCDSPYV TKYYGSYLKD TKLWIIMEYL GGGSALDLLE PGPLDETQIA TILREILKGL 120

DYLHSEKKIH RDIKAANVLL SEHGEVKLAD FGVAGQLTDT QIKRNTFVGT PFWMAPEVIK 180

QSAYDSKADI WSLGITAIEL AKGEPPHSEL HPMKVLFLIP KNNPPTLEGN YSKPLKEFVE 240

ACLNKEPSFR PSAKELLKHK FIIRNAKKTS YLTELIDRYK RWKAEQSQDD SSSEDSDTET 300

DGQASGGSDS GDWIFTIREK DPKNLENGAL QPSDLERNKK KDIPKRPFSQ CLSTIISPLF 360

AELKEKSQAC GGNMGSIEEL RGAIYLAEEA CPGISDTMVA QLVQRLQRYS LSGGGTSSH 419

Nucleotide Sequence
(FASTA)

null 4

Domain Profile

S: 1     yelleeigkGalgkvylarekktgelvaikkinlekq.ekleelqkeisvlkklkhpniv  59

         ++ le+igkG++g+v+++ +++t+++vaik+i+le+  +++e++q+ei+vl+++++p+++

Q: 12    FTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAeDEIEDIQQEITVLSQCDSPYVT  71

         7889*******************************99899********************

S: 60    eylesflkeeelwlvmeylagGslsdlvkeelkselkEeqiayilrevlkaLeylHskkv  119

         +y++s+lk+++lw++meyl gGs+ dl++     +l+E+qia+ilre+lk+L+ylHs+k+

Q: 72    KYYGSYLKDTKLWIIMEYLGGGSALDLLE---PGPLDETQIATILREILKGLDYLHSEKK  128

         *****************************...****************************

S: 120   iHrdikakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaqeekgYde  179

         iHrdika+n+Ll+e+geVkL+dfgva ql++t+ kr+t+vgtp+wmAPEvi+  ++ Yd+

Q: 129   IHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIK--QSAYDS  186

         ****************************************************..9*****

S: 180   kaDiwslGItaielaegepPfkdleplkallkilkneppklkskkkfskefkefvekclq  239

         kaDiwslGItaiela+gepP+++l+p+k+l++i+kn+pp+l+ +  +sk +kefve+cl+

Q: 187   KADIWSLGITAIELAKGEPPHSELHPMKVLFLIPKNNPPTLEGN--YSKPLKEFVEACLN  244

         *****************************************776..**************

S: 240   knpekRpsasellkhkFl  257

         k+p++Rpsa+ellkhkF+

Q: 245   KEPSFRPSAKELLKHKFI  262

         *****************7

Domain Sequence
(FASTA)

FTKLEKIGKG SFGEVFKGID NRTQKVVAIK IIDLEEAEDE IEDIQQEITV LSQCDSPYVT 60

KYYGSYLKDT KLWIIMEYLG GGSALDLLEP GPLDETQIAT ILREILKGLD YLHSEKKIHR 120

DIKAANVLLS EHGEVKLADF GVAGQLTDTQ IKRNTFVGTP FWMAPEVIKQ SAYDSKADIW 180

SLGITAIELA KGEPPHSELH PMKVLFLIPK NNPPTLEGNY SKPLKEFVEA CLNKEPSFRP 240

SAKELLKHKF I 251

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006917	; P:induction of apoptosis
GO:0008631	; P:intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0030336	; P:negative regulation of cell migration
GO:0046777	; P:protein autophosphorylation
GO:0048679	; P:regulation of axon regeneration

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013