EKS-LOA-00396

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LOA-00396

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE11	364.3	5.4E-109	368	628	261

Status

Unreviewed

Ensembl Protein

ENSLAFP00000022377

UniProt Accession

G3SVZ6;

Protein Name

Protein Synonyms/Alias

Gene Name

MAP3K2

Gene Synonyms/Alias

MAP3K2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLAFG00000005303	ENSLAFP00000022377	ENSLAFT00000027415
ENSLAFG00000005303	ENSLAFP00000004444	ENSLAFT00000005306

Organism

Loxodonta africana

Functional Description

Protein Length

630

Protein Sequence
(FASTA)

SDDQQALNSI MQDLAVLHKA SRPALSLQET RKTKSLSPKK QNDVRVKFEH RGEKRYRILQ 60

FSRPVKLEDL RSKAKVAFGQ SMDLHYTNNE LVIPLTTQDD LDKAVELLDR SIHMKSLKIL 120

LVSSKGENRI NFHFLLQATN LEPLPSLEDL DNTVFGAERK KRLSVIGSTS RDRSSPPPGY 180

IPDELHQVAR NGSFTSINSE GEFIPESMDQ LMLDPLSLSS PENSGSGSCP SLDSPLDGEN 240

YPKSRMPRAQ SYPDNHQEFS DYDNPIFEKF GKGGTYPRRY HVSYHQQEYN DGRKTFPRAR 300

RNQGTSFRSP VSFSPTDHSL STSSGSSIFT PECDDSRIRR RGSDIDNPTL TVMDISPPSR 360

SPRAPTNWRL GKLLGQGAFG RVYLCYDVDT GRELAVKQVQ FDPDSPETSK EVNALECEIQ 420

LLKNLLHERI VQYYGCLRDP QEKTLSIFME YMPGGSIKDQ LKAYGALTEN VTRKYTRQIL 480

EGVHYLHSNM IVHRDIKGAN ILRDSTGNVK LGDFGASKRL QTICLSGTGM KSVTGTPYWM 540

SPEVISGEGY GRKADIWSVA CTVVEMLTEK PPWAEFEAMA AIFKIATQPT NPKLPPHVSD 600

YTRDFLKRIF VEAKLRPSAD ELLRHMFVHY 630

Nucleotide Sequence
(FASTA)

null 4

Domain Profile

S: 1     wqkrevigkGsfgsvyaaldvdtgellavKeveikpekksekkevkalkeEikllkelkH  60

         w+ ++++g+G+fg+vy+++dvdtg+ lavK+v+++p++ +++kev+al++Ei+llk+l H

Q: 368   WRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLH  427

         78899*******************************************************

S: 61    enivkyyGv..eveeeelkiflEyvegGslssllekygkleesvikkytkqileglayLH  118

         e+iv+yyG+  + +e++l+if+Ey++gGs++++l++yg+l+e+v++kyt+qileg++yLH

Q: 428   ERIVQYYGClrDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLH  487

         *********777899*********************************************

S: 119   ekkivHRDiKgaNilldssgvvklsDFGaskrlaelntkaaelesltGtlaymaPEvikk  178

         +++ivHRDiKgaNil ds+g+vkl+DFGaskrl++++ + + ++s+tGt+++m+PEvi++

Q: 488   SNMIVHRDIKGANILRDSTGNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISG  547

         **********************************************************99

S: 179   kekgygrkaDiWslgcvviemltgkrPfaeldeelaimfkvgakktkPeipeklseegkd  238

         +  gygrkaDiWs++c+v+emlt+k+P+ae+ e++a++fk++++ t+P++p ++s+ ++d

Q: 548   E--GYGRKADIWSVACTVVEMLTEKPPWAEF-EAMAAIFKIATQPTNPKLPPHVSDYTRD  604

         8..****************************.9***************************

S: 239   flekcleldpkkrpsaeeLLkhefl  263

         fl++++ +++k rpsa+eLL+h+f+

Q: 605   FLKRIF-VEAKLRPSADELLRHMFV  628

         ******.899*************96

Domain Sequence
(FASTA)

WRLGKLLGQG AFGRVYLCYD VDTGRELAVK QVQFDPDSPE TSKEVNALEC EIQLLKNLLH 60

ERIVQYYGCL RDPQEKTLSI FMEYMPGGSI KDQLKAYGAL TENVTRKYTR QILEGVHYLH 120

SNMIVHRDIK GANILRDSTG NVKLGDFGAS KRLQTICLSG TGMKSVTGTP YWMSPEVISG 180

EGYGRKADIW SVACTVVEML TEKPPWAEFE AMAAIFKIAT QPTNPKLPPH VSDYTRDFLK 240

RIFVEAKLRP SADELLRHMF V 261

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity
GO:0071260	; P:cellular response to mechanical stimulus
GO:0045893	; P:positive regulation of transcription, DNA-dependent

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000270	; OPR_PB1.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF00564	; PB1; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00666	; PB1; 1.
SM00220	; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013