EPS-LOA-00113

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-LOA-00113

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/PRL	155.1	4.3E-46	82	149	68

Status

Unreviewed

Ensembl Protein

ENSLAFP00000005513

UniProt Accession

G3SYE6;

Protein Name

Protein Synonyms/Alias

Gene Name

PTP4A1

Gene Synonyms/Alias

PTP4A1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLAFG00000006572	ENSLAFP00000005513	ENSLAFT00000006568

Organism

Loxodonta africana

Functional Description

Protein Length

174

Protein Sequence
(FASTA)

MARMNRPAPV EVTYKNMRFL ITHNPTNATL NKFIEELKKY GVTTIVRVCE ATYDTALVEK 60

EGIHVLDWPF DDGAPPSNQI VDDWLSLVKI KFREEPGCCI AVHCVAGLGS RAPVLVALAL 120

IEGGMKYEDA VQFIRQKRRG AFNSKQLLYL EKYRPKMRLR FKESNGHRNN CCIQ 174

Nucleotide Sequence
(FASTA)

ATGGCTCGAA TGAACCGCCC AGCTCCTGTG GAAGTCACAT ACAAGAACAT GAGATTTCTT 60

ATTACACACA ATCCAACCAA TGCGACCTTA AACAAATTTA TAGAGGAACT TAAGAAATAT 120

GGAGTTACCA CAATAGTAAG AGTATGTGAA GCAACTTATG ACACTGCTCT TGTGGAAAAA 180

GAAGGCATCC ATGTTCTTGA TTGGCCTTTT GATGATGGTG CCCCACCATC CAACCAGATT 240

GTTGATGACT GGTTAAGTCT TGTAAAAATT AAGTTTCGTG AAGAACCTGG TTGTTGTATT 300

GCTGTTCATT GTGTTGCAGG TCTTGGGAGC AGAGCTCCAG TGCTTGTTGC CCTAGCATTA 360

ATTGAAGGTG GAATGAAATA TGAAGATGCC GTACAGTTCA TAAGACAAAA GCGGCGTGGA 420

GCTTTTAACA GCAAGCAACT TTTGTATTTG GAGAAGTATC GTCCTAAAAT GCGGCTGCGC 480

TTCAAAGAGT CCAATGGTCA TAGAAACAAC TGTTGTATTC AGTAA 525

Domain Profile

S: 1     ddwlslvkikfreepGsciavhcvaGlG.rapvlvalaliesGmkyedavqfirqkrrGa  59

         ddwlslvkikfreepG+ciavhcvaGlG rapvlvalalie+GmkyedavqfirqkrrGa

Q: 82    DDWLSLVKIKFREEPGCCIAVHCVAGLGsRAPVLVALALIEGGMKYEDAVQFIRQKRRGA  141

         8**************************989******************************

S: 60    inskqlly  67

         +nskqlly

Q: 142   FNSKQLLY  149

         *******9

Domain Sequence
(FASTA)

DDWLSLVKIK FREEPGCCIA VHCVAGLGSR APVLVALALI EGGMKYEDAV QFIRQKRRGA 60

FNSKQLLY 68

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0009898	; C:internal side of plasma membrane
GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0030335	; P:positive regulation of cell migration
GO:0006470	; P:protein dephosphorylation

KEGG

InterPros

IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR000387	; Tyr/Dual-specificity_Pase.

Pfam

PF00782

; DSPc; 1.

SMARTs

Prosites

PS50056

; TYR_PHOSPHATASE_2; 1.

Prints

Created Date

20-Feb-2013