EPS-LOA-00026

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-LOA-00026

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	188.4	2.5E-55	784	1030	247

Status

Unreviewed

Ensembl Protein

ENSLAFP00000006459

UniProt Accession

G3T0G7;

Protein Name

Protein Synonyms/Alias

Gene Name

PHLPP2

Gene Synonyms/Alias

PHLPP2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLAFG00000007685	ENSLAFP00000006459	ENSLAFT00000007684

Organism

Loxodonta africana

Functional Description

Protein Length

1320

Protein Sequence
(FASTA)

MKRNGSRNCL NRRSRFGSRE RDWLREDVKR GCVYLYGAET TTATTTTTTS SSSSDVHLVL 60

CTVETPASEI CAGEGKESLY LQLHGDLVSR RLEPTERPLQ IVYDYLSRLG FDDPLRIQEE 120

ATNPDLGCMI RFYGEKPCQV DHLDRILLSG IYNVRKGKTQ LHKWAERLVV LCGTCLIVSS 180

VKDCQTGKMH ILPLVGGKVD EVKRRQYSLA FSSAGAQAQT YHVSFETLAE CQRWQRQASK 240

VVSQRISTVD LSCYSLEEVP EHLFYSQDIT YLNLRHNFMQ LERPGGLDSL YKFSQLKGLN 300

LSHNKLGLFP VFLCEISTLT ELNLSCNGIH DLPSQIGNLL NLQTLCLDGN FLTILPEELG 360

NLQQLSSLGI SFNHFSQIPE VYEKLTTVEK VVMAGNQLEV LNLGVLNRMS HIKHVDLRMN 420

RLKTMVIENL EGNKYITHMD LRDNQLTDLD LSSLRSLEQL HCERNQLREL TLSGFSLRTL 480

YANSNRLTAV NVYPVPSLLT SLELSRNLLE CIPDWACEAK KIEILDVSYN LLTEVSMMFP 540

LRILSSLSLR KLMVGHNHVQ SLPVLMEHIP LEVLDIQHNL LSRLPDTLFS KALNLRYLNA 600

SANSLESLPS ACTGEESLSM LQLLYLTSNL LTDQCIPMLV GHPHLRILHL ANNQLQTFPA 660

SKLNKLEQLE ELNLSGNKLK TIPTTIANCK RLHTLVAHSN NISIFPEILQ LPQIQFVDLS 720

CNDLTEILIP EALPTTLQDL DLTGNTNLVL EHKTLDIFSH ITTLKIDQKP LPTTDSSVTS 780

TFWSHGLAEM AGQRNKLCIS ALAVDNFAEG VGAAYGMFDG DRNEELPRLL QCTMADVLLE 840

EVQQSTNDTV FMTNTFLVSH RKLGMAGQKL GSSALLCYVR PDTADPTSSF SLTVANVGTC 900

QAVLCRSGKP VSLSKVFSLE QDPEEAQRVK DQKAIITEDN KVNGVTCCTR MLGCTYLHPW 960

ILPQPHISSI PLTIQDELLI LGNKALWEHL SYTEAINAVR HVQDPLAAAK KLCTLAQSYG 1020

CQDNVGAMVV YLNIGEEGCT CEVNGLTLPG PVGFVSTIKD PPKPTTPSSS SGIASEFSSE 1080

MSTSEVSSEV GSTASDEHNT IGLDSGLLPR PERRCSLHPT PTSGVFQRQP SCATFSSNQS 1140

DNGLDSDDDQ PVEGVITNGS KVEVEVDIHC CRGGDLENSP TFKETSPTRC PEEHARGLSF 1200

GIRRQNSMNS GILLPVSKDK MELQKSPSTS CLYGKKLSNG SIVPLEDSLN LIEVATEAPK 1260

KKTGYFAAPT QLEPEDQFVV PRDLEEEVKE QMKQHQESRP EPEPSEEDRT EALEEFDTAL 1320

Nucleotide Sequence
(FASTA)

ATGAAACGCA ATGGGAGCAG AAATTGTTTG AATCGGAGAA GCAGGTTTGG TTCTCGAGAA 60

AGAGATTGGC TGAGAGAAGA TGTGAAGAGA GGCTGTGTTT ACCTTTATGG AGCAGAAACA 120

ACCACTGCCA CTACAACCAC CACCACCTCC TCCTCCTCCT CTGATGTACA TCTCGTCCTT 180

TGCACAGTGG AGACACCAGC ATCTGAAATA TGTGCTGGAG AGGGAAAGGA AAGCCTTTAT 240

TTACAGCTTC ATGGAGACTT GGTCAGCAGG AGATTGGAAC CTACTGAACG ACCTCTTCAG 300

ATCGTTTATG ATTATTTATC CAGGCTGGGC TTTGATGATC CTCTGCGCAT ACAGGAGGAG 360

GCAACAAATC CTGACCTTGG CTGTATGATT CGATTTTATG GTGAAAAACC ATGCCAGGTG 420

GATCATCTGG ACCGAATCCT CCTGTCTGGC ATCTATAATG TACGCAAGGG AAAGACCCAG 480

CTGCATAAGT GGGCTGAACG CCTAGTTGTC CTCTGTGGCA CCTGCCTCAT TGTTTCCTCA 540

GTGAAGGACT GTCAAACTGG AAAGATGCAC ATTTTGCCTC TGGTTGGGGG AAAGGTAGAC 600

GAAGTGAAGC GACGGCAGTA CTCACTTGCA TTCAGCTCAG CTGGAGCCCA AGCTCAGACT 660

TATCATGTCA GCTTTGAGAC TTTGGCCGAG TGCCAGAGGT GGCAACGGCA AGCATCCAAG 720

GTGGTGTCCC AGCGAATTAG TACAGTTGAT CTCTCATGTT ACAGCCTTGA GGAGGTTCCT 780

GAGCATCTCT TCTACAGTCA AGATATCACC TACCTCAACT TGCGACACAA TTTTATGCAA 840

CTAGAAAGAC CAGGGGGCCT TGATTCTCTT TACAAATTTT CTCAGCTGAA GGGCCTGAAC 900

TTGTCCCATA ATAAACTTGG GTTGTTTCCT GTATTCCTGT GTGAGATCTC TACCCTGACT 960

GAGCTCAACC TTTCCTGTAA TGGAATTCAC GACCTGCCAA GTCAGATTGG CAATCTGCTA 1020

AATCTTCAAA CTCTCTGTCT TGATGGCAAC TTTCTAACTA TTTTACCTGA AGAATTGGGA 1080

AATCTGCAGC AGCTTTCCTC CCTGGGAATT TCCTTCAACC ACTTTAGTCA AATTCCTGAG 1140

GTTTATGAGA AGCTTACTAC CGTAGAAAAA GTGGTTATGG CAGGAAATCA ACTAGAAGTC 1200

CTAAACCTGG GGGTGCTGAA TAGGATGAGC CATATCAAAC ATGTAGATTT AAGGATGAAC 1260

CGTTTGAAGA CCATGGTTAT TGAAAATCTG GAGGGAAATA AATACATCAC CCACATGGAT 1320

CTGCGAGACA ATCAACTGAC TGACTTAGAT CTTAGCTCCT TACGTAGTTT GGAGCAGCTG 1380

CACTGTGAGC GGAACCAACT GAGGGAGCTA ACACTCAGTG GATTCTCCCT TCGGACTCTC 1440

TACGCCAACT CCAACAGGCT GACCGCAGTG AATGTTTATC CAGTACCCAG TCTCCTCACT 1500

TCCCTAGAGC TCTCCCGAAA CCTGTTAGAG TGTATCCCTG ACTGGGCCTG TGAAGCAAAG 1560

AAGATAGAAA TATTAGATGT CAGTTATAAT CTCCTCACAG AGGTTTCCAT GATGTTCCCC 1620

CTTAGAATTC TGAGTAGCTT GAGTCTTAGA AAACTGATGG TGGGACACAA CCATGTGCAA 1680

AGCCTTCCTG TGCTAATGGA GCACATCCCC CTTGAAGTAC TGGACATTCA GCATAACTTA 1740

CTCTCCAGGT TGCCAGATAC CCTCTTCTCC AAGGCCTTAA ATCTCAGGTA CCTGAATGCA 1800

TCTGCAAATA GCCTGGAGTC TTTACCATCT GCTTGTACTG GGGAGGAGAG TCTGAGTATG 1860

CTGCAGTTGC TTTACCTGAC CAGCAATCTC CTGACAGATC AGTGTATACC TATGCTGGTG 1920

GGGCACCCAC ACCTGCGAAT CTTGCATCTT GCAAACAATC AACTACAGAC CTTTCCCGCA 1980

AGCAAACTCA ATAAATTGGA GCAATTGGAA GAATTGAACC TAAGTGGCAA CAAGCTAAAA 2040

ACCATTCCCA CGACTATAGC AAACTGCAAA AGGCTGCACA CCCTTGTTGC ACACTCCAAC 2100

AACATCAGCA TTTTCCCAGA AATACTGCAG TTGCCTCAGA TCCAGTTTGT AGACCTAAGT 2160

TGCAATGACT TGACAGAAAT CCTGATTCCA GAGGCTCTGC CTACTACATT ACAAGACCTT 2220

GATCTGACTG GAAATACAAA TCTGGTTCTA GAACACAAGA CCCTGGACAT ATTTAGCCAT 2280

ATCACAACTC TGAAAATTGA TCAGAAACCT TTGCCAACCA CTGATTCTTC AGTCACATCA 2340

ACTTTCTGGA GCCATGGACT GGCTGAGATG GCAGGACAGA GAAATAAGCT ATGTATATCT 2400

GCCCTAGCTG TGGATAACTT TGCAGAGGGG GTGGGAGCTG CATATGGCAT GTTTGATGGG 2460

GACCGAAATG AGGAGCTCCC TCGCCTACTG CAGTGTACAA TGGCAGATGT GCTTTTGGAA 2520

GAGGTACAGC AGTCAACAAA TGACACAGTT TTCATGACTA ACACCTTCTT GGTATCTCAC 2580

AGAAAATTAG GAATGGCTGG CCAGAAGCTG GGCTCCTCTG CTCTCCTGTG TTACGTCCGA 2640

CCTGACACTG CTGATCCAAC AAGTAGTTTT AGCTTGACTG TGGCCAACGT TGGTACCTGC 2700

CAAGCAGTCC TGTGCCGAAG TGGGAAACCA GTGTCCCTCT CTAAAGTCTT CAGCCTAGAA 2760

CAGGACCCAG AGGAGGCACA AAGAGTTAAG GACCAAAAAG CCATCATAAC AGAGGACAAC 2820

AAAGTGAATG GGGTAACCTG CTGTACCCGG ATGCTGGGCT GTACATACCT CCACCCTTGG 2880

ATCCTTCCCC AGCCCCACAT ATCTTCCATT CCACTTACTA TTCAGGATGA GTTGCTAATT 2940

CTTGGGAACA AAGCATTGTG GGAACACTTG TCATATACAG AAGCTATTAA TGCAGTGCGT 3000

CATGTACAAG ACCCTTTAGC AGCTGCCAAG AAGCTGTGCA CCTTAGCACA GAGCTATGGT 3060

TGTCAGGACA ATGTGGGGGC CATGGTAGTT TATTTGAACA TTGGCGAGGA AGGTTGCACT 3120

TGTGAAGTGA ATGGGCTCAC CCTTCCAGGT CCTGTGGGAT TTGTTTCAAC CATCAAGGAC 3180

CCCCCCAAGC CAACCACTCC TTCCTCTAGT AGTGGTATTG CCTCTGAGTT CAGCAGTGAA 3240

ATGTCCACCT CAGAGGTGAG CAGTGAAGTG GGATCCACGG CTTCTGATGA ACATAACACT 3300

ATTGGCCTGG ATTCTGGCTT GCTTCCAAGG CCAGAGAGGC GCTGCAGCCT TCATCCAACA 3360

CCCACCTCTG GGGTTTTTCA GCGCCAGCCT TCTTGTGCTA CTTTCTCAAG TAATCAGTCT 3420

GACAATGGCC TGGACAGTGA TGATGATCAG CCCGTTGAAG GGGTGATAAC AAATGGCAGC 3480

AAGGTAGAAG TAGAAGTAGA TATTCATTGC TGTAGAGGAG GAGACCTTGA GAACTCTCCT 3540

ACTTTTAAAG AGACTTCCCC TACCCGGTGT CCTGAGGAAC ATGCTAGAGG CTTGTCTTTT 3600

GGGATCCGAA GACAGAACAG TATGAATAGT GGCATACTTC TGCCAGTGAG CAAGGACAAG 3660

ATGGAATTAC AGAAGTCTCC CTCTACTTCC TGTCTCTATG GAAAGAAACT CTCCAATGGC 3720

TCTATTGTGC CCCTAGAAGA TAGCCTGAAT CTCATTGAAG TGGCCACAGA AGCCCCCAAG 3780

AAGAAAACTG GCTATTTTGC TGCCCCAACA CAGCTGGAGC CAGAGGATCA GTTTGTTGTA 3840

CCTCGTGACC TGGAAGAAGA AGTGAAGGAG CAAATGAAAC AGCACCAGGA AAGCAGGCCC 3900

GAGCCTGAGC CCAGTGAAGA GGATCGGACC GAGGCCCTGG AGGAGTTTGA CACAGCACTG 3960

TAA 3963

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g++++ g+rn+++ ++ +++nf++  ++      +g++DG++++e  + +++++ ++l

Q: 784   SHGLAEMAGQRNKLCISALAVDNFAEGVGA-----AYGMFDGDRNEELPRLLQCTMADVL  838

         6899*********************99775.....89***********************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

          ee++    ++++ + +++++Fl  +++l       ++ +k Gs+a++++++++

Q: 839   LEEVQ----QSTNDTVFMTNTFLVSHRKL------GMAGQKLGSSALLCYVRPDtadpts  888

         ***99....77888889************......89***************999999**

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsre.dEleRieeaggsvilkdgaRvlGvL  172

           +l+vanvG ++avLcr+gk+v+ls+ ++ +++ +E +R++++++ +++++  +v+Gv+

Q: 889   sfSLTVANVGTCQAVLCRSGKPVSLSKVFSLEQDpEEAQRVKDQKAIITEDN--KVNGVT  946

         ******************************99866**********9999998..******

S: 173   avsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekk  232

         +++R+lG++yl+p++ p+P+++s++lt +de liL+ + lw+++s  ea+++vr+v +

Q: 947   CCTRMLGCTYLHPWILPQPHISSIPLTIQDELLILGNKALWEHLSYTEAINAVRHVQD--  1004

         **********************************************************..

S: 233   eaeqeaakkLvklalargskdnvsaivv  260

           + +aakkL++la+++g++dnv a+vv

Q: 1005  --PLAAAKKLCTLAQSYGCQDNVGAMVV  1030

         ..************************97

Domain Sequence
(FASTA)

SHGLAEMAGQ RNKLCISALA VDNFAEGVGA AYGMFDGDRN EELPRLLQCT MADVLLEEVQ 60

QSTNDTVFMT NTFLVSHRKL GMAGQKLGSS ALLCYVRPDT ADPTSSFSLT VANVGTCQAV 120

LCRSGKPVSL SKVFSLEQDP EEAQRVKDQK AIITEDNKVN GVTCCTRMLG CTYLHPWILP 180

QPHISSIPLT IQDELLILGN KALWEHLSYT EAINAVRHVQ DPLAAAKKLC TLAQSYGCQD 240

NVGAMVV 247

Keyword

Complete proteome; Leucine-rich repeat; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>