EKS-LOA-00399

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LOA-00399

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE11	338.3	4.5E-101	1057	1320	264

Status

Unreviewed

Ensembl Protein

ENSLAFP00000006737

UniProt Accession

G3T125;

Protein Name

Protein Synonyms/Alias

Gene Name

YSK4

Gene Synonyms/Alias

YSK4;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLAFG00000008034	ENSLAFP00000006737	ENSLAFT00000008035

Organism

Loxodonta africana

Functional Description

Protein Length

1324

Protein Sequence
(FASTA)

IMMFLLAERH AESLLDICHD TNSSPTDTIT VTKNQNINLA KPHSSEEFDQ DDDCSHSILV 60

REGDSSGDTQ GWPPRTEGVE IIVTFPRDAI HSQEKSQEES KENNQITSAH QKWTRAQSAS 120

LPNEIEMADL RTQTLAMQTF LREKEESSKE VCDVNLDFLL PRACLEPSSS KSVTREDVLH 180

FPKGQQRKSE EISTSVMQHS SRRIEFPLPP LSLLPRRPGL LTIPQDHKAH KERKKHIPSL 240

LSFVPKILEP TSQSDEFRPS NKQQEALCKV FSDQTLRSSD SSIWSRNMCS FQNAHLHREN 300

LEVEKNWKLK ETERCNKVES SRFEKGQSLV CFENYEEDSI LIDMKGDTGY HGSEVRKVGE 360

DSQYLSSRNK KCLILRNYEQ EPEIACTIPS KLQETQYLEV TQGQDEEARN GKIDSKHASV 420

HKSEATEQNH EELDEYPVLK SFSNIVSGDP TEKLPGGHSG METNIKISVA EATKPEMNEM 480

VPLICITFPG DGDPKEPAIA KPSLQKRKGT LHTNNNSFNI LAHQENDKHK MKPYRNKLDS 540

KTKISNRIPQ SFMSSTEGSV KPTMHKTSIK TQVFPALGLI DPRPQQSPKF QRRIPQIEKK 600

QSTYSALKPK RPSFPCICKN PVIKKSSVPF SVQPTEPNLN YLDLKYSDMF KEINSTGNGP 660

GIYEMFGTPI YCHVREAGRH ENKYYHEISS APSGRCITNK CRSSHGERSS NGRTRHFQKR 720

PHSKPPKTSL GIKQKHKSLH SKEKSCKPVA RNLEGSENDD GIAEPDWQGK SSGNDFLSFK 780

NDVSPMKLAQ YPEQLIEQKE FLPVSDLSIV EEVSLEQSTN EGGDSNNQLL ATSLRDLHEL 840

EELHHQIPSE NSRAMPSEKN SNKHVLQEKQ NEASLSNLKA NQILTDDLEF GGVSDKPKTL 900

TSVSFHEKQE SATSQRYKNW AYSLDDDSLS DTSITCQMLG KALNDENSIS QEILNSVKNE 960

ELTDELLCCL AAELLALDEK DNSCQIMADE TDPESLNLDF SRRVSTTQEL GREATNVKTQ 1020

KYSNGFRIYD REEKFLNSNE KKTFSENSLK YGEPILWTKG EILGKGAYGT VYCGLTSQGQ 1080

LIAVKQVALD TSDKLSTEKE YRKLQEEVDL LKVLKHVNIV AYLGTCLEEN IVSIFMEFVP 1140

GGSISSIINR FGPLPEMVFC KYTKQILQGV AYLHENCVVH RDIKGNNVML MPTGIIKLID 1200

FGCAKRLAWA GLNGTHSDML KSMHGTPYWM APEVINESGY GRKSDIWSIG CTVFEMATGK 1260

PPLASMDRMA AMFYIGAHRG LMPPLPDHFS EHAADFVRVC LTRDQRERPS ALQLLKHSFL 1320

KRSH 1324

Nucleotide Sequence
(FASTA)

null 4

Domain Profile

S: 1     wqkrevigkGsfgsvyaaldvdtgellavKeveikp.ekksekkevkalkeEikllkelk  59

         w+k+e++gkG++g+vy++l+ ++g+l+avK+v++++ +k s++ke+++l+eE++llk lk

Q: 1057  WTKGEILGKGAYGTVYCGLT-SQGQLIAVKQVALDTsDKLSTEKEYRKLQEEVDLLKVLK  1115

         89*****************8.89***********8615667888****************

S: 60    HenivkyyGveveeeelkiflEyvegGslssllekygkleesvikkytkqileglayLHe  119

         H niv y+G++ ee+ ++if+E+v+gGs+ss+++++g+l e+v++kytkqil+g+ayLHe

Q: 1116  HVNIVAYLGTCLEENIVSIFMEFVPGGSISSIINRFGPLPEMVFCKYTKQILQGVAYLHE  1175

         ************************************************************

S: 120   kkivHRDiKgaNilldssgvvklsDFGaskrlaelntkaae...lesltGtlaymaPEvi  176

         +++vHRDiKg+N++l+ +g++kl DFG++krla++  + ++   l+s++Gt+++maPEvi

Q: 1176  NCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLAWAGLNGTHsdmLKSMHGTPYWMAPEVI  1235

         **********************************999988877899**************

S: 177   kkkekgygrkaDiWslgcvviemltgkrPfaeldeelaimfkvgakk.tkPeipeklsee  235

         +++  gygrk+DiWs+gc+v+em+tgk+P a++ +++a+mf +ga++  +P++p+++se+

Q: 1236  NES--GYGRKSDIWSIGCTVFEMATGKPPLASM-DRMAAMFYIGAHRgLMPPLPDHFSEH  1292

         988..****************************.9**********9979***********

S: 236   gkdflekcleldpkkrpsaeeLLkhefl  263

         + df++ cl++d+++rpsa +LLkh+fl

Q: 1293  AADFVRVCLTRDQRERPSALQLLKHSFL  1320

         **************************96

Domain Sequence
(FASTA)

WTKGEILGKG AYGTVYCGLT SQGQLIAVKQ VALDTSDKLS TEKEYRKLQE EVDLLKVLKH 60

VNIVAYLGTC LEENIVSIFM EFVPGGSISS IINRFGPLPE MVFCKYTKQI LQGVAYLHEN 120

CVVHRDIKGN NVMLMPTGII KLIDFGCAKR LAWAGLNGTH SDMLKSMHGT PYWMAPEVIN 180

ESGYGRKSDI WSIGCTVFEM ATGKPPLASM DRMAAMFYIG AHRGLMPPLP DHFSEHAADF 240

VRVCLTRDQR ERPSALQLLK HSFL 264

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013