EKS-LOA-00211

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LOA-00211

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NKF3	565.2	6.2E-170	1333	1667	335

Status

Unreviewed

Ensembl Protein

ENSLAFP00000007695

UniProt Accession

G3T398;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100657736

Gene Synonyms/Alias

LOC100657736;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLAFG00000009180	ENSLAFP00000007695	ENSLAFT00000009180

Organism

Loxodonta africana

Functional Description

Protein Length

1750

Protein Sequence
(FASTA)

MSACNTFTEH VWKPGECKNC FKPKSLHQLP PDPEKAPITH GNVKTNANHS NNHRIRNTGN 60

FRPPVAKKPT IAVKPTMMVA DGQSVCGELS IQEHCENKPV IIGWNRNRTA LNQKPLNNNN 120

EDDIEGFSHV PKPHSSNDIA KKISNNNNGL TEVLKEIAGL DTTPQIRGNE TNSRETFLGR 180

INNCYKRSLE RKLPPSCMMG GIKDTQGKHV ILSGSTEVIS NEGGRFCYPE FSSGEESEED 240

VFFSNVEEEH ESWDESDEEL LAMEIRMRGQ PRFANFRANT LSPVRFFVDK KWNTVPLRNK 300

SLQRICAVDY DDSYDEILNG YEENSVVSYG PGSIQSMVSS DSTTPDSSLT EESRSETASS 360

LSQKICNGGL SPGNQGDPKN MKEIEPNYES LSGNNQEDSS QTPKSPIKVP ETHKAVLALR 420

LEEKDGKIAV QTEKQESKAS TDIAGQAVTI NLVPVEEQAK PYRVVNLEQP LCKPYTVVDV 480

SAAMASEHLE GPVKSFKMKS SSSTPNSPVT SPALASGQVS AHFQKSSAIR YQEVWTSSTS 540

PRQKIPKVEL ISGGTGPNVP PRKNCHKSAP TSPTATNISS RTIPVKSPNL SEIKFNSYNN 600

AGMPPFPIII HDEPTYARSS KNAIKVPIVI NPNAYDNLAI YRSFLGTSGE LSAKEKTTSI 660

ISHTYEEIET ESQVSDSTTN KPTECPQAKG FSNSTERKRG SVAQKVQEFN NCLNRAQSSP 720

QRNYSSSHSS PAKIQRTTQE PVAKTEDTQE SQTVGSGSST REKASTVLSQ IVASIQPPQS 780

PPEMPPSGPK ACSVEELYAV PPDADTAKST PKSTPVRPKS LFTSQPSGEA EAPQTTESPT 840

TKVQKDPLSK PVTTPPSKLV MSPQSEPAPP FPPPRSTSSP YHASNLLQRH FTNWTKPTSP 900

TRSTEAESVL HSEGSRRATD AKPKRWISFK SFFRRRKTDE EDEKEKEREK GKLVGLDGTV 960

IHMLPPPPVQ RHHWFTETKA ESSEKPAIVF MYRCDPAQGQ LSVDQSQAGA NQTAVMEKSG 1020

KEDTFLQDSE KKKRSHSSPS QLPKKILSHV THEVTAEDFS PRDPRTIVVK QDGRGCTSAT 1080

SALPLPELER EEEKEDTSDP VDLSSCSATY SNNTGQSRAA MIPPKHPRQP KGALDDAITF 1140

GGKTDQEAPN ASQPTPPPLP KKMIIRANTE PISKDLQKSL ESSLCVMANP TYDIDPNWDA 1200

SSAGSSISYE LKGLDIESYD SLERPLQRER PIPSAANSIS SLTTLSIKDR FSNSTESLSS 1260

RRGPSCRQGR SIQKPQRQAL YRGLENREEV VGKIRSLYTD ALKKLAVKCE DLFMAGQKDQ 1320

LRFGVDSWSD FRLTSDKPCC EAGDAVYYTA SYAKDPLNNY AVKICKSKAK ESQQYYHSLA 1380

VRQSLAVHFN IQQDCGHFLA EVPNRLLPWD DPDGPETEED KVEETEEEVK GEADGKSPEP 1440

CSETESSQKE SEGVVSRKQR SHVVVITREV PCLTVADFVR DSLAQHGKSP DVYERQVCLL 1500

LLQLCSGLEH LKPYHVTHCD LRLENLLLVH YQPGGTAQCL GPAEPSPTSS CPTRLIVSNF 1560

SQAKQKSHLV DPEILRDQSR LAPEIITATQ YKKCDEFQTG ILIYEMLHLP NPFDENPELK 1620

EKEYTRADLP RIPLRSPYSR GLQQLASCLL NPNPSERILI SDAKGILQCL LWGPREDLFQ 1680

TFAASPSLVQ RNALLQNWLD IKRTLLMIKF AEKSLDREGG ISLEDWLCAQ YLAFATTDSL 1740

SCIVKILQHR 1750

Nucleotide Sequence
(FASTA)

null 4

Domain Profile

S: 1     ltsdkpcceagdavyytasyakdplsnyavkickskekksqsy.....vrqslpvhfniq  55

         ltsdkpcceagdavyytasyakdpl+nyavkicksk+k+sq+y     vrqsl+vhfniq

Q: 1333  LTSDKPCCEAGDAVYYTASYAKDPLNNYAVKICKSKAKESQQYyhslaVRQSLAVHFNIQ  1392

         79**********************************************************

S: 56    qdcGhflaevpsrlla..dpdapekd...................pkpasetepsake..  92

         qdcGhflaevp+rll+  dpd pe +                   p+p+sete+s+ke

Q: 1393  QDCGHFLAEVPNRLLPwdDPDGPETEedkveeteeevkgeadgksPEPCSETESSQKEse  1452

         *****************9*****99899********************************

S: 93    .......rdhvvvitrevphltvadfvrdslashraepelyerrvcllllqlcsGlehlk  145

                r+hvvvitrevp+ltvadfvrdsla+h+++p++yer+vcllllqlcsGlehlk

Q: 1453  gvvsrkqRSHVVVITREVPCLTVADFVRDSLAQHGKSPDVYERQVCLLLLQLCSGLEHLK  1512

         ************************************************************

S: 146   eygvihrdlrlenlllvhlqpqagaaqaaapaepaptsaapsaapaattasqegprekql  205

         +y+v+h+dlrlenlllvh+qp +g+aq+ +paep+pts++p

Q: 1513  PYHVTHCDLRLENLLLVHYQP-GGTAQCLGPAEPSPTSSCP-------------------  1552

         *********************.*******************...................

S: 206   trlivsnflkakqksgglvdlqikkdqarlapeivsasqykkfdefqtGiliyellhlpn  265

         trlivsnf++akqks +lvd++i++dq+rlapei++a+qykk+defqtGiliye+lhlpn

Q: 1553  TRLIVSNFSQAKQKS-HLVDPEILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPN  1611

         9**************.********************************************

S: 266   pfevraelkereyrredlprlpllslysrGlqqlasllleadpikriliseakrvl  321

         pf++++elke+ey+r+dlpr+pl+s+ysrGlqqlas+ll+++p++rilis+ak++l

Q: 1612  PFDENPELKEKEYTRADLPRIPLRSPYSRGLQQLASCLLNPNPSERILISDAKGIL  1667

         ******************************************************98

Domain Sequence
(FASTA)

LTSDKPCCEA GDAVYYTASY AKDPLNNYAV KICKSKAKES QQYYHSLAVR QSLAVHFNIQ 60

QDCGHFLAEV PNRLLPWDDP DGPETEEDKV EETEEEVKGE ADGKSPEPCS ETESSQKESE 120

GVVSRKQRSH VVVITREVPC LTVADFVRDS LAQHGKSPDV YERQVCLLLL QLCSGLEHLK 180

PYHVTHCDLR LENLLLVHYQ PGGTAQCLGP AEPSPTSSCP TRLIVSNFSQ AKQKSHLVDP 240

EILRDQSRLA PEIITATQYK KCDEFQTGIL IYEMLHLPNP FDENPELKEK EYTRADLPRI 300

PLRSPYSRGL QQLASCLLNP NPSERILISD AKGIL 335

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0015629	; C:actin cytoskeleton
GO:0005925	; C:focal adhesion
GO:0005524	; F:ATP binding
GO:0004715	; F:non-membrane spanning protein tyrosine kinase activity
GO:0016477	; P:cell migration
GO:0046777	; P:protein autophosphorylation
GO:0034446	; P:substrate adhesion-dependent cell spreading

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR008266	; Tyr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00109	; PROTEIN_KINASE_TYR; 1.

Prints

Created Date

20-Feb-2013