EPS-LOA-00129

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-LOA-00129

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PDP	402.9	4.0E-121	288	498	211

Status

Unreviewed

Ensembl Protein

ENSLAFP00000008389

UniProt Accession

G3T4T7;

Protein Name

Protein Synonyms/Alias

Gene Name

PDP1

Gene Synonyms/Alias

PDP1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLAFG00000010019	ENSLAFP00000008389	ENSLAFT00000010014

Organism

Loxodonta africana

Functional Description

Protein Length

596

Protein Sequence
(FASTA)

MSISALLSMG RCRCRCCCPR GLWMLSAPCR DDRRMCVCPG PRRVGIPVRS SSLPLFSDAM 60

PAPTQLFFPL IRNCELSRIY GTVCYCHHKH FCCSSPHVPQ SRLRCTPHPA YATFCRPKEN 120

WWQYTQGRRY ASTPQKFYLT PPQVNSILKA NEYSFKVPEF DGKNVSSILG FDSNQLPANA 180

PIEDRRSAAT CLQTRGMLLG VFDGHAGCAC SQAVSERLFY YIAVSLLPHE TLLEIENAVE 240

SGRALLPILQ WHKHPNDYFS KEASKLYFNS LRTYWQELID LNTGESADID VKEALINAFK 300

RLDNDISLEA QVGDPNSFLN YLVLRVAFSG ATACVAHVDG VDLHVANTGD SRAMLGVQEE 360

DGSWSAVTLS NDHNAQNQRE LERLKLEHPK NEAKSVVKQD RLLGLLMPFR AFGDVKFKWS 420

IDLQKRVIES GPDQLNDNEY TKFIPPNYYT PPYLTAEPEV TYHRLRPQDK FLVLATDGLW 480

ETMHRQDVVR IVGEYLTGMH HQQPIAVGGY KVTLGQMHGL LTERRAKMSS VFEDQNAATH 540

LIRHAVGNNE FGAVDHERLS KMLSLPEELA RMYRDDITII VVQFNSHVVG AYQNQE 596

Nucleotide Sequence
(FASTA)

ATGAGCATCT CTGCCTTGCT TTCAATGGGC CGGTGCCGCT GTCGCTGCTG CTGTCCGCGC 60

GGGTTGTGGA TGTTGTCGGC TCCGTGTCGT GATGACAGGA GAATGTGTGT GTGTCCCGGG 120

CCCAGACGAG TTGGAATCCC AGTCAGAAGT TCCAGCCTGC CGTTATTTTC GGATGCCATG 180

CCAGCACCAA CTCAACTGTT TTTTCCCCTG ATCCGTAACT GTGAACTGAG CAGAATCTAC 240

GGCACTGTAT GTTACTGTCA CCACAAGCAC TTCTGCTGCT CGTCACCCCA CGTTCCTCAG 300

AGCCGCCTGA GATGCACACC CCATCCAGCA TATGCTACCT TTTGCAGGCC AAAGGAGAAC 360

TGGTGGCAGT ACACCCAAGG AAGGAGATAT GCTTCCACAC CACAGAAGTT TTACCTCACG 420

CCTCCACAGG TCAACAGCAT TCTTAAAGCT AATGAATATA GTTTCAAGGT GCCAGAATTT 480

GATGGCAAAA ATGTCAGCTC TATCCTTGGG TTTGACAGCA ACCAGCTGCC TGCAAATGCA 540

CCTATCGAGG ACCGGCGAAG TGCAGCAACC TGCTTGCAAA CCAGAGGGAT GCTCTTGGGG 600

GTTTTCGATG GCCATGCAGG CTGTGCTTGT TCCCAGGCGG TCAGTGAAAG ACTCTTTTAT 660

TATATCGCTG TCTCTTTGTT GCCCCACGAG ACCTTGTTAG AGATTGAAAA TGCAGTGGAG 720

AGTGGTCGAG CACTGTTACC CATTCTCCAG TGGCACAAGC ACCCTAATGA TTACTTCAGT 780

AAGGAGGCAT CCAAATTGTA CTTCAACAGC TTAAGGACTT ACTGGCAAGA GCTTATAGAC 840

CTCAATACTG GGGAGTCAGC CGACATTGAT GTTAAGGAAG CTTTGATTAA TGCTTTTAAG 900

AGGCTTGATA ATGACATCTC CTTGGAGGCC CAAGTTGGTG ATCCCAATTC TTTCCTCAAC 960

TACCTGGTGC TTCGAGTGGC ATTTTCTGGG GCCACCGCTT GTGTGGCCCA TGTGGATGGT 1020

GTTGACCTTC ATGTGGCCAA TACGGGTGAT AGCAGAGCCA TGCTGGGTGT GCAGGAAGAG 1080

GACGGCTCTT GGTCAGCAGT TACTCTCTCT AATGACCACA ATGCTCAGAA TCAAAGAGAA 1140

CTGGAACGGC TGAAATTGGA ACACCCGAAG AATGAGGCCA AGAGTGTGGT GAAGCAGGAT 1200

CGGCTGCTTG GCTTGCTGAT GCCTTTTAGG GCTTTTGGAG ATGTCAAGTT CAAATGGAGC 1260

ATTGACCTTC AAAAGAGAGT GATAGAATCT GGCCCAGACC AATTGAATGA TAATGAATAT 1320

ACCAAGTTTA TCCCTCCTAA TTACTACACA CCTCCTTATC TCACTGCTGA GCCAGAGGTA 1380

ACTTACCACC GATTAAGGCC ACAGGATAAG TTTCTGGTGT TGGCTACTGA TGGGTTGTGG 1440

GAGACTATGC ATAGGCAGGA TGTGGTTAGA ATTGTGGGTG AGTATCTAAC TGGCATGCAT 1500

CACCAACAGC CAATAGCTGT TGGTGGCTAC AAGGTGACTC TGGGACAGAT GCATGGCCTT 1560

TTAACAGAAA GGAGAGCCAA GATGTCCTCA GTATTTGAGG ATCAGAATGC AGCAACCCAT 1620

CTCATCCGCC ATGCTGTGGG CAACAATGAG TTTGGAGCAG TTGATCACGA GCGCCTCTCC 1680

AAAATGCTTA GTCTTCCTGA AGAGCTTGCT CGGATGTACA GAGATGACAT TACAATCATC 1740

GTTGTTCAGT TCAATTCTCA TGTCGTAGGG GCATATCAAA ACCAAGAA 1788

Domain Profile

S: 2     didvkealvnafkrldedisleaqvsdedevlrylvlrvalsGataclahvdGvdlhvan  61

         didvkeal+nafkrld+disleaqv+d++++l+ylvlrva+sGatac+ahvdGvdlhvan

Q: 288   DIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVAN  347

         89**********************************************************

S: 62    tGdsravlGvqeedgswsavklsrdhnaqneselerlkaehpkseaktvikedrllglli  121

         tGdsra+lGvqeedgswsav+ls+dhnaqn++elerlk+ehpk+eak+v+k+drllgll+

Q: 348   TGDSRAMLGVQEEDGSWSAVTLSNDHNAQNQRELERLKLEHPKNEAKSVVKQDRLLGLLM  407

         ************************************************************

S: 122   plrafGdvkfkwskelqkrvvesgfdvladney.kfiapnyytppyltaepevtyhrlrp  180

         p+rafGdvkfkws++lqkrv+esg+d+l+dney kfi+pnyytppyltaepevtyhrlrp

Q: 408   PFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYtKFIPPNYYTPPYLTAEPEVTYHRLRP  467

         ************************************************************

S: 181   qdkflvlasdGlwdllsredvvrlvgeylae  211

         qdkflvla+dGlw++++r+dvvr+vgeyl+

Q: 468   QDKFLVLATDGLWETMHRQDVVRIVGEYLTG  498

         ****************************875

Domain Sequence
(FASTA)

DIDVKEALIN AFKRLDNDIS LEAQVGDPNS FLNYLVLRVA FSGATACVAH VDGVDLHVAN 60

TGDSRAMLGV QEEDGSWSAV TLSNDHNAQN QRELERLKLE HPKNEAKSVV KQDRLLGLLM 120

PFRAFGDVKF KWSIDLQKRV IESGPDQLND NEYTKFIPPN YYTPPYLTAE PEVTYHRLRP 180

QDKFLVLATD GLWETMHRQD VVRIVGEYLT G 211

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005739	; C:mitochondrion
GO:0046872	; F:metal ion binding
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0035970	; P:peptidyl-threonine dephosphorylation

KEGG

InterPros

IPR001932	; PP2C-like.
IPR000222	; PP2C_Mn2_Asp60_BS.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481

; PP2C; 1.

SMARTs

SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

PS01032

; PP2C; 1.

Prints

Created Date

20-Feb-2013