EPS-LOA-00022

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-LOA-00022

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	212.9	8.5E-63	716	961	246

Status

Unreviewed

Ensembl Protein

ENSLAFP00000008582

UniProt Accession

G3T587;

Protein Name

Protein Synonyms/Alias

Gene Name

PHLPP1

Gene Synonyms/Alias

PHLPP1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLAFG00000010242	ENSLAFP00000008582	ENSLAFT00000010245

Organism

Loxodonta africana

Functional Description

Protein Length

1054

Protein Sequence
(FASTA)

EAAEKATPPP TLYVQLHGET TRRLEADEKP LQIQNDYLFQ LGFGELWRVQ EEGMDSEIGC 60

LIRFYAGKPH STGSLERIQL SGMYNVRKGK MQLPVNRWTR RQVILCGTCL IVSSVKDSMT 120

GKMHVLPLIG GKVEEVKKHQ HCLAFSSSGP QSQTYYICFD TFTEYLRWLR QVSKVASQRI 180

SSVDLSCCSL EHLPANLFYS QDLTHLNLKQ NFLRQIPSLP AARGLNELQR FTKLKSLNLS 240

NNHLGDFPLA VCNIPTLTEL NVSCNALRAV PAAVGVMHNL QTFLLDGNFL QSLPAELESM 300

HQLSYLGLSF NEFTDIPEVL EKLTAVDKLC MSGNCMETLR LQALRKMPHI KHVDLRLNVI 360

RKLIADEVDF LQHVTQLDLR DNKLGDLDAM IFNNIEVLHC ERNQLVTLRI CGYFLKALYA 420

SSNELVQLDV YPIPNYLSYM DISRNRLESV PEWVCESRKL EVLDIGHNQI CELPARLFCN 480

SSLRKLLAGH NQLTRLPERL ERTLVEVLDV QHNQLLELPP SLLMKADSLR FLNASANKLE 540

TLPPATLSEE TSSILQELYL TNNNLTDKCV PLLTGHPHLK ILHMAYNRLQ SFPASKMAKL 600

EELEEVDISG NKLKAIPTTI MNCRRMHTVI AHSNCIEVFP EVMQLPEMKC VDLSCNELSE 660

VTLPENLPPK LQELDLTGNP RLTLDHKTLE LLNNIRCFKI DQPSAGDASG APAVWSHGYT 720

EASGVKNKLC VAALSVNNFC DNREALYGVF DGDRNVEVPY LLQCTMSDIL AEELQKTKHE 780

EEYMVNTFIV MQRKLGTAGQ KLGGAAVLCH IKHDPVDPGG SFTLTSANVG KCQTVLCRNG 840

KPLPLSRSYS MSCEEELKRI KQHKAIITED GKVNGVTEST RILGYTFLHP SVVPRPHVQS 900

VTLTPQDEFF ILGSKGLWDS LSIEEAVEAV RNVPDALAAA KKLCTLAQSY GCHDSISAVV 960

VQLNVTEDSF CCCELSASGA VPPPSPGIFP SSVNMVIKDR PSDGLGMPSS SSGMASEISS 1020

EISTSEMSSE VGSTASDEPP SGALNESSPA YPSE 1054

Nucleotide Sequence
(FASTA)

GAGGCCGCGG AGAAGGCGAC CCCGCCGCCC ACCCTGTACG TGCAGCTTCA CGGAGAGACC 60

ACCCGGCGGC TGGAGGCGGA CGAGAAGCCA CTGCAGATCC AAAATGACTA CCTCTTCCAG 120

CTGGGATTCG GGGAGTTGTG GAGGGTGCAG GAGGAAGGCA TGGACTCGGA GATCGGCTGC 180

CTTATCCGCT TCTATGCAGG AAAACCTCAC AGCACTGGTA GCTTGGAACG GATTCAACTC 240

TCAGGAATGT ATAATGTCCG TAAAGGTAAA ATGCAGTTGC CAGTGAACCG ATGGACAAGA 300

CGCCAAGTTA TCCTGTGTGG GACCTGCCTA ATAGTATCAT CTGTAAAAGA CAGCATGACC 360

GGAAAGATGC ATGTTCTGCC ACTAATTGGT GGAAAAGTAG AAGAAGTGAA AAAGCACCAG 420

CACTGTTTAG CATTTAGCTC CTCTGGACCC CAAAGCCAGA CTTACTACAT TTGTTTTGAT 480

ACTTTCACAG AGTATTTAAG GTGGCTTAGA CAAGTCTCCA AGGTTGCATC ACAGCGTATT 540

AGCTCAGTGG ACCTCTCGTG TTGTAGCCTG GAGCATCTTC CTGCCAACCT CTTCTACAGC 600

CAGGACCTCA CTCATCTCAA TTTAAAACAA AACTTCCTAA GGCAAATCCC CAGCCTGCCA 660

GCTGCCAGAG GGCTCAATGA ACTGCAAAGG TTCACCAAGT TGAAGAGTCT TAACCTTTCC 720

AATAATCATT TAGGGGATTT CCCGTTAGCA GTGTGCAATA TTCCAACCCT GACAGAGCTG 780

AATGTGTCCT GCAACGCCCT GAGAGCAGTT CCAGCCGCAG TTGGAGTTAT GCACAATTTG 840

CAGACATTTC TGTTGGATGG AAATTTTCTC CAGTCGCTTC CTGCTGAGTT GGAGAGCATG 900

CACCAGCTTA GTTATCTTGG TCTTTCTTTC AATGAATTCA CTGACATTCC AGAGGTATTG 960

GAGAAATTGA CCGCTGTGGA TAAACTTTGT ATGTCTGGAA ACTGTATGGA GACTCTGAGG 1020

CTACAGGCTT TAAGAAAAAT GCCTCACATT AAACATGTGG ATTTAAGATT GAATGTAATT 1080

AGGAAGCTAA TAGCAGATGA AGTGGACTTT CTCCAGCATG TCACCCAGCT TGACCTGCGT 1140

GACAATAAAC TGGGTGATCT AGACGCTATG ATTTTCAACA ACATCGAAGT TCTGCACTGT 1200

GAAAGAAATC AACTGGTGAC TTTGCGCATC TGTGGCTATT TCCTAAAAGC ACTCTATGCC 1260

TCTTCTAATG AACTTGTTCA ACTTGACGTT TACCCAATTC CAAATTATCT GTCGTACATG 1320

GATATTTCAA GGAACCGCTT AGAAAGTGTG CCTGAGTGGG TATGTGAAAG CCGAAAGCTG 1380

GAAGTTTTGG ATATTGGCCA TAATCAAATA TGTGAGCTCC CTGCACGCTT ATTTTGTAAT 1440

AGTAGTCTCC GGAAACTACT GGCAGGACAC AACCAGCTGA CAAGGCTACC TGAGAGGCTA 1500

GAAAGAACCT TAGTGGAGGT CTTGGATGTG CAACACAACC AGCTTCTTGA ACTGCCTCCT 1560

AGCCTTCTGA TGAAGGCTGA CAGCCTGAGG TTCCTGAATG CATCTGCAAA CAAACTGGAA 1620

ACTCTTCCTC CAGCCACGCT TTCTGAAGAG ACAAGCAGCA TCTTACAAGA GTTGTATTTG 1680

ACAAATAACA ACCTCACAGA TAAGTGTGTG CCCTTGTTAA CAGGGCACCC CCATCTGAAG 1740

ATCCTCCACA TGGCCTATAA CCGACTTCAA AGTTTCCCAG CAAGTAAAAT GGCGAAACTG 1800

GAGGAACTTG AGGAAGTTGA TATCAGTGGG AATAAACTGA AAGCTATCCC AACCACCATC 1860

ATGAACTGCA GGCGTATGCA CACCGTGATC GCTCACTCCA ATTGCATTGA AGTCTTTCCT 1920

GAGGTTATGC AGCTCCCAGA AATGAAGTGC GTAGATCTGA GCTGTAATGA GCTAAGCGAA 1980

GTCACTTTAC CAGAAAACCT GCCTCCAAAA CTACAAGAAC TAGACCTGAC TGGAAACCCC 2040

CGACTCACCC TCGATCACAA AACCCTGGAG CTGCTGAATA ATATCCGCTG TTTTAAGATT 2100

GACCAGCCTT CAGCAGGAGA TGCCTCAGGA GCCCCAGCCG TATGGAGCCA CGGTTACACT 2160

GAAGCTTCTG GGGTGAAGAA CAAGTTGTGT GTTGCGGCCC TGTCGGTGAA CAACTTCTGT 2220

GACAACCGGG AAGCCCTGTA TGGTGTATTT GATGGAGACC GCAATGTGGA GGTGCCCTAC 2280

CTTCTCCAGT GCACCATGAG CGACATTCTG GCTGAGGAGC TACAGAAAAC AAAGCATGAA 2340

GAAGAGTACA TGGTCAATAC ATTCATTGTT ATGCAAAGGA AACTTGGAAC TGCTGGGCAG 2400

AAGCTTGGAG GTGCTGCTGT CCTTTGTCAT ATCAAGCACG ACCCTGTGGA CCCAGGCGGG 2460

TCCTTCACCT TGACCTCAGC TAACGTGGGC AAGTGCCAGA CGGTTCTCTG TCGGAACGGG 2520

AAGCCGTTGC CTCTGTCCAG ATCTTACAGC ATGAGCTGTG AGGAAGAACT GAAGAGAATC 2580

AAACAGCACA AAGCCATCAT CACAGAGGAC GGCAAGGTGA ATGGCGTGAC TGAGTCCACC 2640

CGCATCCTGG GCTACACGTT CCTCCACCCC AGCGTGGTGC CTCGTCCTCA CGTGCAGTCC 2700

GTGACGTTAA CCCCACAGGA CGAGTTCTTC ATCCTCGGCA GCAAGGGCTT GTGGGACAGC 2760

CTGTCCATCG AGGAGGCCGT GGAGGCTGTG CGGAACGTGC CCGACGCTCT GGCTGCTGCC 2820

AAGAAGCTGT GCACCCTAGC CCAGAGCTAT GGCTGCCATG ACAGCATCAG CGCGGTAGTG 2880

GTGCAGCTCA ACGTCACCGA GGACAGCTTC TGCTGCTGTG AGCTCAGTGC CAGCGGGGCA 2940

GTACCGCCGC CCAGCCCGGG CATCTTTCCC TCCTCCGTCA ACATGGTCAT CAAGGACCGG 3000

CCCTCCGATG GGCTGGGCAT GCCCTCCTCC AGTAGTGGCA TGGCCTCGGA GATCAGCAGC 3060

GAGATCTCCA CCTCGGAGAT GAGCAGTGAG GTGGGGTCGA CAGCCTCCGA CGAGCCCCCC 3120

TCCGGTGCCC TGAATGAGAG CAGCCCCGCG TACCCCAGCG AG 3162

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g+++ +g +n+++ a+ s++nf++++e+     ++gv+DG+++ ev + +++++++il

Q: 716   SHGYTEASGVKNKLCVAALSVNNFCDNREA-----LYGVFDGDRNVEVPYLLQCTMSDIL  770

         689***********************9885.....9************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

         aeel+    ++++ ++++ ++F+ ++++l       ++ +k G +av+++ik++

Q: 771   AEELQ----KTKHEEEYMVNTFIVMQRKL------GTAGQKLGGAAVLCHIKHDpvdpgg  820

         ***99....999*****************......99***********************

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvLa  173

           +l+ anvG++++vLcrngk+++ls+ +++s+e+El+Ri+++++ ++++   +v+Gv++

Q: 821   sfTLTSANVGKCQTVLCRNGKPLPLSRSYSMSCEEELKRIKQHKAIITEDG--KVNGVTE  878

         *99*****************************************9999998..*******

S: 174   vsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekke  233

          +R lG ++l+p v+p+P+v+s++lt++def+iL+s+Glwd +s eeav++vr+v +

Q: 879   STRILGYTFLHPSVVPRPHVQSVTLTPQDEFFILGSKGLWDSLSIEEAVEAVRNVPD---  935

         *********************************************************...

S: 234   aeqeaakkLvklalargskdnvsaivv  260

          + +aakkL++la+++g++d++sa+vv

Q: 936   -ALAAAKKLCTLAQSYGCHDSISAVVV  961

         .************************97

Domain Sequence
(FASTA)

SHGYTEASGV KNKLCVAALS VNNFCDNREA LYGVFDGDRN VEVPYLLQCT MSDILAEELQ 60

KTKHEEEYMV NTFIVMQRKL GTAGQKLGGA AVLCHIKHDP VDPGGSFTLT SANVGKCQTV 120

LCRNGKPLPL SRSYSMSCEE ELKRIKQHKA IITEDGKVNG VTESTRILGY TFLHPSVVPR 180

PHVQSVTLTP QDEFFILGSK GLWDSLSIEE AVEAVRNVPD ALAAAKKLCT LAQSYGCHDS 240

ISAVVV 246

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>