| Tag | Content |
|---|
| EKPD ID | EKS-LOA-00383 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| TK/Src | 298.5 | 4.5E-89 | 348 | 524 | 177 |
|
| Status | Unreviewed |
| Ensembl Protein | ENSLAFP00000009603 |
| UniProt Accession | G3T7L2; |
| Protein Name | |
| Protein Synonyms/Alias | |
| Gene Name | LCK |
| Gene Synonyms/Alias | LCK; |
| Ensembl Information | |
| Organism | Loxodonta africana |
| Functional Description | |
| Protein Length | 539 |
Protein Sequence
(FASTA) | | MGCSCSSNPE DDWMENIDVC ENCHYPIVPL DSKAMLPMRN GSDVRDPLVT YEGSIPPASP 60 | | LQDNLVIALH NYEPSHDGDL GFEKGEQLRI LEQSGEWWKA QSLTTGQEGF IPFNFVAKAN 120 | | SLEPEPWFFK NLSRKDAERQ LLAPGNTHGS FLIRESESTV GSFSLSVRDF DQNQGEVVKH 180 | | YKIRNLDNGG FYISPRITFP GLHELVRHYT NAPDGLCTRL SRPCQTQKPQ KPWWEDEWEV 240 | | PRETLKLVER LGAGQFGEVW MGYYNGHTKV AVKSLKQGSM SPDAFLAEAN LMKQLQHQRL 300 | | VRLYAVVTQE PIYIITEYME NGALQAPRSP APLLDLSSFC SLCSLLMLLP TGSLVDFLKT 360 | | PPGIKLTINK LLDMAAQIAE GMAFIEERNY IHRDLRAANI LVSDTLSCKI ADFGLARLIE 420 | | DNEYTAREGA KFPIKWTAPE AINYGTFTIK SDVWSFGILL TEIVTHGRIP YPGMTNPEVI 480 | | QNLERGYRMV RPDNCPEELY DLMLLCWKER PEDRPTFDYL RSVLEDFFTA TEGQYQPQP 539 |
|
Nucleotide Sequence
(FASTA) | |
| Domain Profile | S: 75 lmakGslldflkeeegkklklpklvdlaaqvaeGmayleeknlihrdlaarnvlvgeslv 134 | l+ Gsl+dflk+ g kl+++kl+d+aaq+aeGma++ee+n+ihrdl+a+n+lv+++l | Q: 348 LLPTGSLVDFLKTPPGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLS 407 | 5678******************************************************** |
| S: 135 vkvadfGlarlieddeytakegaklPikWtaPeaiklgkftiksdvWsfGillteivtkG 194 | +k+adfGlarlied+eyta+egak+PikWtaPeai++g+ftiksdvWsfGillteivt+G | Q: 408 CKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHG 467 | ************************************************************ |
| S: 195 kvPypGmtneevleqvergyrlprpeecpeelyelllecwkkdpeerPtfetlqevl 251 | ++PypGmtn ev++++ergyr+ rp++cpeely+l+l cwk++pe+rPtf++l++vl | Q: 468 RIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYDLMLLCWKERPEDRPTFDYLRSVL 524 | *****************************************************9876 |
|
Domain Sequence
(FASTA) | | LLPTGSLVDF LKTPPGIKLT INKLLDMAAQ IAEGMAFIEE RNYIHRDLRA ANILVSDTLS 60 | | CKIADFGLAR LIEDNEYTAR EGAKFPIKWT APEAINYGTF TIKSDVWSFG ILLTEIVTHG 120 | | RIPYPGMTNP EVIQNLERGY RMVRPDNCPE ELYDLMLLCW KERPEDRPTF DYLRSVL 177 |
|
| Keyword | ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; SH3 domain; Transferase; Tyrosine-protein kinase. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | | GO:0005794 | ; C:Golgi apparatus | | GO:0005524 | ; F:ATP binding | | GO:0004713 | ; F:protein tyrosine kinase activity | | GO:0050853 | ; P:B cell receptor signaling pathway | | GO:0018108 | ; P:peptidyl-tyrosine phosphorylation | | GO:0045588 | ; P:positive regulation of gamma-delta T cell differentiation | | GO:0010628 | ; P:positive regulation of gene expression | | GO:0042523 | ; P:positive regulation of tyrosine phosphorylation of Stat5 protein | | GO:0046777 | ; P:protein autophosphorylation | | GO:0050856 | ; P:regulation of T cell receptor signaling pathway | | GO:0051209 | ; P:release of sequestered calcium ion into cytosol |
|
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |