EKS-LOA-00444

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LOA-00444

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/ULK	328.3	4.9E-98	4	254	251

Status

Unreviewed

Ensembl Protein

ENSLAFP00000010311

UniProt Accession

G3T976;

Protein Name

Protein Synonyms/Alias

Gene Name

STK36

Gene Synonyms/Alias

STK36;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLAFG00000012325	ENSLAFP00000021909	ENSLAFT00000035672
ENSLAFG00000012325	ENSLAFP00000010311	ENSLAFT00000012331

Organism

Loxodonta africana

Functional Description

Protein Length

1318

Protein Sequence
(FASTA)

MEKYHVLEMI GEGSFGRVYK GRRKYSAQVV ALKFIPKLGR SEKELRNLQR EIEIMRGLRH 60

PNIVHMLDSF ETDKEVVVVT DYAEGELFQI LEDDGKLPED QVQAIAAQLV SALYYLHSHR 120

ILHRDMKPQN ILLAKGGGIK LCDFGFARAM STNTMVLTSI KGTPLYMSPE LVEERPYDHT 180

ADLWSVGCIL YELAVGTPPF YTTSIFELVS LILKDPVRWP STLSPCFKNF LQGLLTKDPR 240

QRLSWPDLLH HPFIAGHVTI ITEPAALDLG TPFTSRLPPE LQVLKDEQAH RLAPKGSESR 300

ILRQARKRMA EEAKQKKHQN TESALEQEDR TSKVAPGTAP LPRLRATPQE PGLLAGILAS 360

EMKSSWAEWG AGEAPSTPRE HQITVDCEQA FPELKSEVVG QRSIDAVDLE NEEPDSDEEW 420

QHLLETIKPV PIQLKSPLTL LCNPDFCQRI QSQLQETGGQ ILKGILEDVS HMLPALRVLS 480

SLLSGCSDSV ALYSFCREAG LPGLLLSLLK HSQESTNIQQ QSWYGTFLRD LIAVIQAYFA 540

CTFNLERSQT SDSLQVFQEA VSLFLDLLGK LLAQPDDSEQ TLRRDSLMCF TVVCEAMDGN 600

SRAISQAFYS SLLTTQRAVL DGLLQGLTVP QLPFHTPPGA PQVSQPLREQ SEDLPGAISC 660

ALAAICTAPV GLPGCWEAKE QVSRYLANQL TEDSSQLRPS LVSGLQHPIL CLHLLKVLYS 720

CCHVSERLCH LLGQEPLALE SMLMLVQGKV KVMDWEESTE VALYLLSLLV LRLQDLPSGM 780

EKLGSETATL FTHSHVVSLV SAAASLLEQL CQQGVTLDLQ PVEWIAAATH ALSAPAEVRL 840

TPPGGCGFYD GLLILLLQLL TQVRGKTSLI RDMASSEMWT ILWHRFSMAL RLPEEVSTQE 900

EELSLSSPQS PEPDWTLISP QGMAALLSLA VATFTQEPQL CLSHLSQRGS ILMSTLKHLL 960

SSSFLHQLGQ APHGSEFLPA VVLSVCQLLC FPFALDVDAD LLIGILADLR DSEVAAHLLQ 1020

VCCHHLVLPQ VELPMSLLTR LALTDPTSLS QFVNTVAASP SSIISFFSVA LLGDQPLLTS 1080

DLLSLLAHTA RVLPPSHLSF IQELLAGSDE SYRPLRSLLG HPDNSVRART YGLLGHLLQH 1140

SMALRGALQS QAGLLNLLLL GLGDKDLAVR RSASFAVGNA AYQAGPLGPA LAAAVPGMTQ 1200

LLGDPQAGIR RNAASALGNL GPEGLGEEML QCQVPQRLLE MACGDPQPNV KEAALIALRS 1260

LRQEPCIHQV LVSLGASEKL ALLSLGNQLL PHSGSSPRPA SAKHCRKLIH LLRPTHST 1318

Nucleotide Sequence
(FASTA)

null 4

Domain Profile

S: 1     ysleeeiGkGsfavvykgrlrkktsqvvAikvvekkkl.kkslenlekeikilkelkhen  59

         y++ e+iG+Gsf+ vykgr rk ++qvvA+k++ k ++ +k+l+nl++ei+i++ l+h+n

Q: 4     YHVLEMIGEGSFGRVYKGR-RKYSAQVVALKFIPKLGRsEKELRNLQREIEIMRGLRHPN  62

         8999***************.******************9*********************

S: 60    ivalldveetskevylvmeycaggdLakllkqkkeLsedtvreflqqlasalkaLhskki  119

         iv++ld++et+kev++v++y++ g+L ++l+++++L+ed+v+++++ql+sal++Lhs++i

Q: 63    IVHMLDSFETDKEVVVVTDYAE-GELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRI  121

         **********************.*************************************

S: 120   vhrDlkPqniLlsyadakkelkkvtlkladFglarvlkeesma.atlkGsplYmaPEvvk  178

         +hrD+kPqniLl+        k +++kl+dFg+ar++++++m  +++kG+plYm+PE+v+

Q: 122   LHRDMKPQNILLA--------KGGGIKLCDFGFARAMSTNTMVlTSIKGTPLYMSPELVE  173

         *************........89********************9****************

S: 179   eqqydakaDlWSiGtilyellvGkpPfaaesiseLvekiekndvleppipkeisselkdl  238

         e+ yd++aDlWS+G+ilyel+vG+pPf+++si+eLv+ i k++v   ++p+++s+++k++

Q: 174   ERPYDHTADLWSVGCILYELAVGTPPFYTTSIFELVSLILKDPV---RWPSTLSPCFKNF  230

         ********************************************...*************

S: 239   lqsLLqrdpkkRisfeelfahpfl  262

         lq+LL++dp++R+s+ +l++hpf+

Q: 231   LQGLLTKDPRQRLSWPDLLHHPFI  254

         **********************96

Domain Sequence
(FASTA)

YHVLEMIGEG SFGRVYKGRR KYSAQVVALK FIPKLGRSEK ELRNLQREIE IMRGLRHPNI 60

VHMLDSFETD KEVVVVTDYA EGELFQILED DGKLPEDQVQ AIAAQLVSAL YYLHSHRILH 120

RDMKPQNILL AKGGGIKLCD FGFARAMSTN TMVLTSIKGT PLYMSPELVE ERPYDHTADL 180

WSVGCILYEL AVGTPPFYTT SIFELVSLIL KDPVRWPSTL SPCFKNFLQG LLTKDPRQRL 240

SWPDLLHHPF I 251

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0042384	; P:cilium assembly
GO:0007228	; P:positive regulation of hh target transcription factor activity
GO:0045880	; P:positive regulation of smoothened signaling pathway
GO:0009791	; P:post-embryonic development

KEGG

InterPros

IPR011989	; ARM-like.
IPR016024	; ARM-type_fold.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013