EPS-LOA-00021

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-LOA-00021

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	234.9	1.7E-69	94	344	251

Status

Unreviewed

Ensembl Protein

ENSLAFP00000011084

UniProt Accession

G3TAY6;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1K

Gene Synonyms/Alias

PPM1K;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLAFG00000013249	ENSLAFP00000011084	ENSLAFT00000013249

Organism

Loxodonta africana

Functional Description

Protein Length

372

Protein Sequence
(FASTA)

MSTAALITLV RSGGNQVRRR VLLSSRLLQD DWLVTPTCHS STSEPRSSRF DPDGSGRPAT 60

WDSFGIWDNR IDEPILLPPS IKYGKPIPKI SLEKVGCASQ IGKRKENEDR FGFAQLTEEV 120

LYFAVYDGHG GPAAADFCHT HMEKCIMDLL PKEKNLESLL TMAFLEIDKA FSRHAHLSAD 180

ATLLTSGTTA TVALLRDGIE LVVASVGDSR AILCRKGKSM KLTIDHTPER KDEKTRIKKS 240

GGFVAWNSLG QPHVNGRLAM TRSIGDLDLK TSGVIAEPET KRIKLHHADD SFLVLTTDGI 300

NFMVNSQEIC DFVNQCHDPT EAAHAVTEQA IQYGTEDNST AVVVPFGAWG KYKNSEINFS 360

FSRSFASSGR WA 372

Nucleotide Sequence
(FASTA)

ATGTCAACAG CTGCCTTAAT TACTTTGGTT AGAAGTGGCG GTAACCAGGT GAGAAGGAGA 60

GTGCTGCTAA GCTCCCGTCT GCTGCAGGAC GACTGGCTGG TGACGCCCAC ATGCCACAGC 120

TCCACCTCAG AGCCCAGGAG TTCTCGGTTT GACCCAGACG GTAGTGGGCG TCCAGCCACC 180

TGGGACAGTT TTGGGATCTG GGATAACCGC ATTGATGAAC CAATTCTGCT GCCACCCAGC 240

ATTAAGTATG GCAAGCCAAT TCCCAAAATC AGCTTGGAAA AGGTGGGCTG CGCCTCGCAG 300

ATTGGCAAAC GGAAAGAGAA TGAAGACCGT TTTGGCTTTG CTCAGTTAAC AGAGGAGGTC 360

CTGTACTTTG CAGTGTATGA TGGGCATGGG GGACCTGCAG CCGCTGATTT CTGTCACACC 420

CACATGGAGA AATGCATTAT GGATTTGCTT CCTAAGGAGA AGAACTTGGA ATCTTTGCTG 480

ACCATGGCTT TTCTAGAAAT AGATAAAGCC TTTTCGAGGC ACGCCCACCT GTCTGCTGAT 540

GCAACCCTTC TGACCTCTGG CACTACTGCG ACGGTAGCCC TATTGCGAGA TGGTATTGAA 600

TTGGTTGTAG CCAGTGTTGG GGACAGCCGG GCTATTTTGT GTAGAAAAGG AAAATCTATG 660

AAGCTGACCA TTGACCATAC TCCAGAAAGG AAAGATGAAA AAACCAGGAT CAAGAAATCT 720

GGTGGCTTTG TAGCTTGGAA TAGTTTGGGA CAGCCTCACG TAAATGGCAG ACTTGCAATG 780

ACAAGGAGTA TTGGAGATTT GGATCTTAAA ACCAGTGGTG TGATTGCAGA ACCTGAAACG 840

AAGAGGATTA AGCTCCATCA TGCTGATGAC AGCTTCCTGG TCCTCACTAC AGATGGAATT 900

AACTTCATGG TGAATAGTCA AGAGATTTGT GACTTTGTCA ATCAGTGCCA TGATCCCACT 960

GAAGCAGCCC ATGCGGTGAC TGAACAGGCA ATACAGTATG GCACAGAAGA TAACAGTACT 1020

GCAGTAGTAG TGCCTTTTGG TGCCTGGGGA AAGTATAAGA ACTCCGAAAT CAACTTCTCA 1080

TTCAGCAGAA GCTTTGCCTC CAGTGGACGA TGGGCCTGA 1119

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         +vg++s+ g+r+e ed++    +f++ +e+   + +f+vyDGhgg  +a+fc++++++++

Q: 94    KVGCASQIGKRKENEDRF----GFAQLTEE---VLYFAVYDGHGGPAAADFCHTHMEKCI  146

         6899**************....67887666...78*************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidk....sGstavvalikds.k  116

            l     +e+++++ l+ aFl++d+++    +++l+ d+    sG+ta+val++d  +

Q: 147   MDLLP----KEKNLESLLTMAFLEIDKAF--SRHAHLSADAtlltSGTTATVALLRDGiE  200

         ***87....********************..44444444445789*************9*

S: 117   lyvanvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkd.ga.RvlGvLav  174

         l+va vGdSra+Lcr+gk+++l+ dH+p+r+dE+ Ri++ gg v+ ++ g+ +v+G La+

Q: 201   LVVASVGDSRAILCRKGKSMKLTIDHTPERKDEKTRIKKSGGFVAWNSlGQpHVNGRLAM  260

         ********************************************98889999********

S: 175   sRalGdlylk.pyvtpePevtshrltsede.fliLasDGlwdvvsneeavslvrdvlekk  232

         +R++Gdl+lk + v++ePe+  ++l++ d+ fl+L +DG+  +v+++e++++v+++++

Q: 261   TRSIGDLDLKtSGVIAEPETKRIKLHHADDsFLVLTTDGINFMVNSQEICDFVNQCHD--  318

         **********566************999999***************************..

S: 233   eaeqeaakkLvklalargskdnvsaivv  260

           ++eaa+ ++++a+++g++dn +a+vv

Q: 319   --PTEAAHAVTEQAIQYGTEDNSTAVVV  344

         ..***********************997

Domain Sequence
(FASTA)

KVGCASQIGK RKENEDRFGF AQLTEEVLYF AVYDGHGGPA AADFCHTHME KCIMDLLPKE 60

KNLESLLTMA FLEIDKAFSR HAHLSADATL LTSGTTATVA LLRDGIELVV ASVGDSRAIL 120

CRKGKSMKLT IDHTPERKDE KTRIKKSGGF VAWNSLGQPH VNGRLAMTRS IGDLDLKTSG 180

VIAEPETKRI KLHHADDSFL VLTTDGINFM VNSQEICDFV NQCHDPTEAA HAVTEQAIQY 240

GTEDNSTAVV V 251

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005739	; C:mitochondrion
GO:0046872	; F:metal ion binding
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0006470	; P:protein dephosphorylation

KEGG

InterPros

IPR001932	; PP2C-like.
IPR000222	; PP2C_Mn2_Asp60_BS.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481

; PP2C; 1.

SMARTs

SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

PS01032

; PP2C; 1.

Prints

Created Date

20-Feb-2013