EKS-LOA-00489

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LOA-00489

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMK1	414.1	2.7E-124	24	275	252

Status

Unreviewed

Ensembl Protein

ENSLAFP00000011462

UniProt Accession

G3TBT2;

Protein Name

Protein Synonyms/Alias

Gene Name

PNCK

Gene Synonyms/Alias

PNCK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLAFG00000013695	ENSLAFP00000011462	ENSLAFT00000013695

Organism

Loxodonta africana

Functional Description

Protein Length

348

Protein Sequence
(FASTA)

MLLLKKQTED ISSVYEIREK LLPTVFGRGA FSEVVLAQER GSTHLVALKC IPKKALRGKE 60

ALVENEIAVL RRVSHPNIVA LEDVHESPSH LYLAMELVTG GELFDRIMER GSYTEKDASH 120

LVGQVLGAVS YLHSLGIVHR DLKPENLLYA TPFEDSKIMV SDFGLSKIQA GNMLGTACGT 180

PGYVAPELLE QKPYGKAVDV WALGVISYIL LCGYPPFYDE SDPELFSQIL RASYEFDSPF 240

WDDISESAKD FIRHLLERDP QKRFTCQQAL QHLWISGDAA FDKDILGSVS EQIQKNFART 300

HWKRAFNATS FLRHIRKAGH SPDGEETSVQ GMTRHTHPGL LATQPPKW 348

Nucleotide Sequence
(FASTA)

null 4

Domain Profile

S: 5     eklGeGafsevlkakekktqkavaikvikkkalkgkeesveneiavlkklkhpnivalkd  64

         + +G+Gafsev++a+e+ +++ va+k+i kkal+gke+ veneiavl++++hpnival+d

Q: 24    TVFGRGAFSEVVLAQERGSTHLVALKCIPKKALRGKEALVENEIAVLRRVSHPNIVALED  83

         568*********************************************************

S: 65    iyesksklylvlelvtGGelfdrivekgvytekdasevikqvleavkylhelgivhrdlk  124

         ++es+s+lyl +elvtGGelfdri+e+g+ytekdas+++ qvl av+ylh+lgivhrdlk

Q: 84    VHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGIVHRDLK  143

         ************************************************************

S: 125   PenllylskeedskikiadfGlskleekellktacGtvgyvapevlkqkkyskkvdvWsi  184

         Penlly+++ edski+++dfGlsk++  ++l tacGt+gyvape+l+qk+y+k+vdvW++

Q: 144   PENLLYATPFEDSKIMVSDFGLSKIQAGNMLGTACGTPGYVAPELLEQKPYGKAVDVWAL  203

         ************************************************************

S: 185   GvityillcGyppfydekeekllekilkgeyefesPyWdeisesakdfikklleldpekr  244

         Gvi+yillcGyppfyde++ +l+++il+++yef+sP+Wd+isesakdfi++lle+dp+kr

Q: 204   GVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHLLERDPQKR  263

         ************************************************************

S: 245   ytieqaledpWi  256

         +t++qal++ Wi

Q: 264   FTCQQALQHLWI  275

         ***********8

Domain Sequence
(FASTA)

TVFGRGAFSE VVLAQERGST HLVALKCIPK KALRGKEALV ENEIAVLRRV SHPNIVALED 60

VHESPSHLYL AMELVTGGEL FDRIMERGSY TEKDASHLVG QVLGAVSYLH SLGIVHRDLK 120

PENLLYATPF EDSKIMVSDF GLSKIQAGNM LGTACGTPGY VAPELLEQKP YGKAVDVWAL 180

GVISYILLCG YPPFYDESDP ELFSQILRAS YEFDSPFWDD ISESAKDFIR HLLERDPQKR 240

FTCQQALQHL WI 252

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Dipodomys ordii"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013