EKS-LOA-00494

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LOA-00494

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/TBCK	421.1	1.5E-126	18	274	257

Status

Unreviewed

Ensembl Protein

ENSLAFP00000015431

UniProt Accession

G3TKR6;

Protein Name

Protein Synonyms/Alias

Gene Name

TBCK

Gene Synonyms/Alias

TBCK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLAFG00000018410	ENSLAFP00000015431	ENSLAFT00000018413

Organism

Loxodonta africana

Functional Description

Protein Length

745

Protein Sequence
(FASTA)

MFPLEDAEMG AFTFFASALP HDVCGSNGLP LTPNSIKILG RFQILKTITH PRLCQYVDIS 60

RGKHAERLVV VAEHCEQSLE DLLRERKPVS YSKVLCIAFE VLQGLQYMNK HGIVHRALAP 120

HNILLDRKGH IKLAKFGLYH MTAHGDDVDF PIGYPSYLAP EVIAQGIFKA TDHMPSEKPL 180

PSGPKSDVWS LGIILFELCM GRKLFQSLDI SERLKFLLTL DCVDDTVIVL AEEHGCLDII 240

KELPENVINL LKKCLTFHPS KRPTAGELMQ DKVFSEVSPL YTPFMKPAGL FSSSLRCADL 300

TLPEDISQLC KDINSDYLAE RSIEEVYYLW CLAGGDLEKE LINKEIIRSK PPICTLPNFL 360

FEDGETFGQD RDRSSLLDDT TVTLSLCQLR NRLKDVGGEA FYPLLEDDQS NLPHSNSNNE 420

LSAAATLPLI IRERDTEYQL NRIILFDRLL KAYPYKKNQI WKEARVDIPP LMRGLTWAAL 480

LGVEGAIHAK YDAIDKDTPI PTDRQIEVDI PRCHQYDELL SSPEGHAKFR RVLKAWVVSH 540

PDLVYWQGLD SLCAPFLYLN FNNEALAYAC MSAFIPKYLY NFFLKDNSHV IQEYLTVFSQ 600

MIAFHDPELS NHLNEIGFIP DLYAIPWFLT MFTHVFPLHK IFHLWDTLLL GNSSFPFCIG 660

VAILQQLRDR LLANGFNECI LLFSDLPEID IERCVRESIN LFCWTPKSAT YRQHAQPAKP 720

TPDSGVRSSA SYFSTECPEP PKTDL 745

Nucleotide Sequence
(FASTA)

null 4

Domain Profile

S: 1     llaqdkdGsnGlplasnakkilGrfqiLkelqhdrLcqYldisrgkh.ervivvaehlel  59

         +l++d++GsnGlpl++n++kilGrfqiLk+++h+rLcqY+disrgkh er++vvaeh+e

Q: 18    ALPHDVCGSNGLPLTPNSIKILGRFQILKTITHPRLCQYVDISRGKHaERLVVVAEHCEQ  77

         589******************************************8869***********

S: 60    sLeDllkerkpvseslvlriayevlsgldylnkhnivhralepksilldrkgqkvkLaky  119

         sLeDll+erkpvs s+vl+ia+evl+gl+y+nkh+ivhral p++illdrkg+ +kLak+

Q: 78    SLEDLLRERKPVSYSKVLCIAFEVLQGLQYMNKHGIVHRALAPHNILLDRKGH-IKLAKF  136

         *****************************************************.******

S: 120   GLyhltayGkdvdfpigygsylaPerilqd.........edkllaatvksDvWsLglill  170

         GLyh+ta+G+dvdfpigy+sylaPe+i+q+         ++k+l++++ksDvWsLg+il+

Q: 137   GLYHMTAHGDDVDFPIGYPSYLAPEVIAQGifkatdhmpSEKPLPSGPKSDVWSLGIILF  196

         ************************************************************

S: 171   elilgikLfaeldlserlkillklstvdetliklaeekkcldiikklderleallkkCLt  230

         el++g+kLf++ld+serlk+ll+l++vd+t+i+laee++cldiik+l+e++++llkkCLt

Q: 197   ELCMGRKLFQSLDISERLKFLLTLDCVDDTVIVLAEEHGCLDIIKELPENVINLLKKCLT  256

         ************************************************************

S: 231   llpskRpspdellkekvf  248

         ++pskRp+ +el+++kvf

Q: 257   FHPSKRPTAGELMQDKVF  274

         ****************98

Domain Sequence
(FASTA)

ALPHDVCGSN GLPLTPNSIK ILGRFQILKT ITHPRLCQYV DISRGKHAER LVVVAEHCEQ 60

SLEDLLRERK PVSYSKVLCI AFEVLQGLQY MNKHGIVHRA LAPHNILLDR KGHIKLAKFG 120

LYHMTAHGDD VDFPIGYPSY LAPEVIAQGI FKATDHMPSE KPLPSGPKSD VWSLGIILFE 180

LCMGRKLFQS LDISERLKFL LTLDCVDDTV IVLAEEHGCL DIIKELPENV INLLKKCLTF 240

HPSKRPTAGE LMQDKVF 257

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005622	; C:intracellular
GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity
GO:0005097	; F:Rab GTPase activator activity
GO:0032851	; P:positive regulation of Rab GTPase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR000195	; Rab-GTPase-TBC_dom.

Pfam

PF00069	; Pkinase; 1.
PF00566	; RabGAP-TBC; 1.

SMARTs

SM00164

; TBC; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS50086	; TBC_RABGAP; 1.

Prints

Created Date

20-Feb-2013