EKS-LOA-00021

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LOA-00021

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/Trio	366.0	1.3E-109	1969	2221	253

Status

Unreviewed

Ensembl Protein

ENSLAFP00000023851

UniProt Accession

G3TQN9;

Protein Name

Protein Synonyms/Alias

Gene Name

SPEG

Gene Synonyms/Alias

SPEG;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLAFG00000023031	ENSLAFP00000023851	ENSLAFT00000036935
ENSLAFG00000023031	ENSLAFP00000017884	ENSLAFT00000022849

Organism

Loxodonta africana

Functional Description

Protein Length

2268

Protein Sequence
(FASTA)

PESRSLAVLA PLQDVDVGAG EMALFECLVA GPTDVEVDWL CRGRLLQPAL LKCKMHFDGR 60

KCKLLLTSVH EDDSGVYTCK LSTAKDELTC SARLTVRPSL APLFTRLLED MEVLEGRAAR 120

FDCKISGTPP PSVSWTHFGR PVEENENLRL RQDGGLHSLH ITHVGSEDEG LYEVSATNTH 180

GQAHCSAQLY VEEPRTAASG PSSKLEKMPS IPEEPEQAEL ERLSIPDFLR PLQDLEVGLA 240

KEALLECQVT GLPYPTISWF HNGHRIQSSE DRRMTQYRDV HRLVFPAVGP QHAGVYKSVI 300

ANKLGKAACY AHLYVTDVVP GPPDGAPQVV AVTGRMITLT WNPPRSLDMA IDPDSLTYTV 360

QHQVLGSDQW TALAKGLREP GWAAMGLRKG IQHVFRVLST SGKSSSKPSP PSEPARLLEH 420

GPPLEEAPTI LDKPDVVYVV EGQPTSVTIT FNHVEAQVVW RSRRGALLEA RAGVYELSQP 480

DDDQYCLRIC RVSRRDLGPL TCTARNRHGT QACSVTLELA EAPRFESIME DMEVGAGETA 540

RFAVVVEGKP LPDVMWYKDE ELLAESSHVS FVYEENECSL VVLSTGAQDG GVYTCTARNL 600

AGEVSCKAEL AVLPVPTAME VEGTGEDEEQ RGRRLSDFYD IHQEIGRGAF SYLRRVVERS 660

SGLEFAAKFI PSQAKPKASA RREARLLARL QHDCIIYFHE AFERRRGLVI VTELYPDKYT 720

ERVYERQYFI CQEVLYTVNK TWPSSGKDPL HSGPQSYSSL LPTHGRGWGQ DRQGSESFGF 780

LLSLPSTQDL HLSPTLSTHR HPTLPLPQPK PLPSSHNSPL PCSLTGISPF VGENDRTTLM 840

NIRNYNVAFE ETTFLSLSRE ARGFLIKVLV RDQLRPTAEE TLEHPWFKVS PSHKVGGTRS 900

GGRETIIMPQ TSSWGPSLGS PDSPESCVPT SVLHWSHAQW LARFSLLLCK LQHCGTRSQD 960

TGREGLNELS TEPCAQLTEG QSHSGISPWI RKEKPGWWLR EASVLVWTAK AKAPRGWASG 1020

PRRQAVSWGA GTQARGLRGL LAPKAQGTGL LGHPVFWDRA WSPGASSLWG PEAGPWEPLV 1080

FCFCTQVQGI LPPVGSLTMG VVVTDQGEGD PQDPRLHGAP PTAPPMDSVS PLSNLEGPSF 1140

PGLQTQAKGA EVSTDHLKLF LSRRRWQALP LPLALSHSLG LSLTLPSCAL TFCSSSSPLP 1200

RPPPIPSFPS GVRSEPEWTW VGQSCSRDPP GLTRLPCLQR SQISYKCHLV LRPIPELLRA 1260

PPERDSEEEE LEELPSVPRP LQPEFSGSRC PSLTFPLRAV FARVASPSPV TPEKRVPSPG 1320

APPGVAEKAR VPTVPRRAGS CLGSSIENLE SEAVFEAKFK RSRESPLSRG LRLLSRSRSE 1380

ERGPFRGAEE DDGMYRPSPA GTPLELVRRP ERSRSVQDLR AAGEPGLVRR LSLSLSQRLR 1440

RTPPAQRHPA WESRGGDGES SEGGSSARGS PVLVVRRRLS STLERLSSRL QRSGSSEDSG 1500

GASGRSTPLF GRLRRATSEG ESLRRLGLPH NQLAAQAGAT TPSAESLGSE ASATSGSSGE 1560

EAPGERRSRL RWGLSRLRKD KGQSQPNLSA GVREDLDFPP VFHIKLKDQV LLEGEAATLL 1620

CLPAACPAPH ISWMKDKQSL QSEPSVVIVS CKDGRQLLSI PRVGKRHSGL YECSATNALG 1680

SITSSCTVAV ARIPGKLTPP EVPQTYQDTA LVLWKPGDSR APCTYTLERR VDGESAWHPV 1740

GSGIPDCYYN VTHLPIGVTV RFRVACVNRA GQGPFSNPSE KVLVRGTQGP ARAPPPDSDS 1800

PTSLAPSPPP TPAPPGPQAA SLSPLSPPKP PSQALSSLKT VGPPPQTPPR KHRGLLATRP 1860

AEPTPPNGQV LPGEPKSSVP DTGTPAPAST PQGAKPASSS TPQYMVTSFV SAPPAPEPPA 1920

PEPPPELTKV TARSFSPGKE AVSSPGSGPP SSRRPEGTTL RQGPPQKPYT FLEEKARGRF 1980

GVVRACRENA TGRTFVAKIV PYAAEGKQRV LQEYEVLRTL HHERLMSLHE AYITPRYLVL 2040

IAESCGNREL LCGLSDRFRY SEDDVATYVV QLLQGLDYLH GHHVLHLDIK PDNLLLAPDN 2100

ALKIVDFGSA QPYNPQALRP LGHRTGTLEF MAPEMVKGEP IGSATDIWGV GVLTYIMLSG 2160

RSPFYEPDPQ ETEARIVGGR FDAFQLYPNT SQSASLFLRK VLSVHPWNRP SLQDCLAHPW 2220

LQDAYLMKLR RQTLTFTTNR LKEFLGEQRR RRAEAATRHK VLLRSYPG 2268

Nucleotide Sequence
(FASTA)

null 4

Domain Profile

S: 1     yevleeigRGrFsvvkkvrekatkravaakfvpkkakkkaqvlrEaeiLkrLqHpllvsl  60

         y++lee++RGrF+vv+ +re+at+r+++ak+vp++a+ k++vl+E+e+L++L+H++l+sl

Q: 1969  YTFLEEKARGRFGVVRACRENATGRTFVAKIVPYAAEGKQRVLQEYEVLRTLHHERLMSL  2028

         99**********************************************************

S: 61    hdayetprslvlilElcsdeeLLdrlaekeslsEsevkaylrqllealqYLHnsrvlHLD  120

         h+ay+tpr+lvli+E+c+++eLL+ l++++++sE++v++y++qll++l+YLH ++vlHLD

Q: 2029  HEAYITPRYLVLIAESCGNRELLCGLSDRFRYSEDDVATYVVQLLQGLDYLHGHHVLHLD  2088

         ************************************************************

S: 121   ikpenllvlaaaeeavkivDlgnAqeltpee..pqekllgtpEfvaPEiiegepvseatD  178

         ikp+nll+  a+++a+kivD+g+Aq ++p++  p  +++gt+Ef+aPE+++gep+++atD

Q: 2089  IKPDNLLL--APDNALKIVDFGSAQPYNPQAlrPLGHRTGTLEFMAPEMVKGEPIGSATD  2146

         ********..********************9999**************************

S: 179   iWavGvlayvlLsgvsPfldeskretllnilkgrvsfseelfaglseeAkeFlkkvLqed  238

         iW+vGvl+y++Lsg+sPf++++ +et+++i+ gr+++++ l+ ++s++A  Fl+kvL+ +

Q: 2147  IWGVGVLTYIMLSGRSPFYEPDPQETEARIVGGRFDAFQ-LYPNTSQSASLFLRKVLSVH  2205

         ***************************************.********************

S: 239   prkRPsaaecLqhpWl  254

         p++RPs+++cL+hpWl

Q: 2206  PWNRPSLQDCLAHPWL  2221

         ***************8

Domain Sequence
(FASTA)

YTFLEEKARG RFGVVRACRE NATGRTFVAK IVPYAAEGKQ RVLQEYEVLR TLHHERLMSL 60

HEAYITPRYL VLIAESCGNR ELLCGLSDRF RYSEDDVATY VVQLLQGLDY LHGHHVLHLD 120

IKPDNLLLAP DNALKIVDFG SAQPYNPQAL RPLGHRTGTL EFMAPEMVKG EPIGSATDIW 180

GVGVLTYIML SGRSPFYEPD PQETEARIVG GRFDAFQLYP NTSQSASLFL RKVLSVHPWN 240

RPSLQDCLAH PWL 253

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Repeat; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR003961	; Fibronectin_type3.
IPR007110	; Ig-like.
IPR013783	; Ig-like_fold.
IPR013098	; Ig_I-set.
IPR003599	; Ig_sub.
IPR003598	; Ig_sub2.
IPR011009	; Kinase-like_dom.
IPR020675	; Myosin_light_ch_kinase-rel.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR015726	; Ser/Thr_kin_striated_muscle-sp.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF07679	; I-set; 8.
PF00069	; Pkinase; 2.

SMARTs

SM00060	; FN3; 2.
SM00409	; IG; 1.
SM00408	; IGc2; 7.

Prosites

PS50853	; FN3; 2.
PS50835	; IG_LIKE; 7.
PS00107	; PROTEIN_KINASE_ATP; 2.
PS50011	; PROTEIN_KINASE_DOM; 2.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013