EKS-MAE-00035

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MAE-00035

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	323.6	6.9E-97	258	505	248

Status

Unreviewed

Ensembl Protein

ENSMEUP00000001788

Gene Name

PAK4

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMEUG00000001949	ENSMEUP00000001788	ENSMEUT00000001960

Organism

Macropus eugenii

Protein Length

524

Protein Sequence
(FASTA)

TIVRGSKGSK DGALTLLLDE FENMSVTRSN SLRRDSPPPP APPHQENGLT EPRDRGSCLG 60

PGEAEGRSRA AERRDHGGSS EAKRDGMEKR PKSSGEGALG PREPSRDKRP LSGPDVRTPR 120

PPGPGGGAKS SASRPFNTYP RADSDHPPRG TGPQGEPHNP APNGPSTGGL PPHSSTKPLP 180

RASRGPEPAL APGTLSPHAS EPQLASRAPP SFGPASHAPS GPRSPQREPQ RVSHEQFRAA 240

LQLVVDPGDP RSYLDNFIKI GEGSTGIVCI ATVRSSGKLV AVKKMDLRKQ QRRELLFNEV 300

VIMRDYQHEN VVEMYNSYLV GDELWVVMEF LEGGALTDIV THTRMNEEQI AAVCLAVLKA 360

LSVLHAQGVI HRDIKSDSIL LTHDGRVKLS DFGFCAQVNK EVPRRKSLVG TPYWMAPELI 420

SRLPYGPEVD IWSLGVMVIE MVDGEPPYFN EPPLKAMKMI RDNLPPKLKN LHKVSPSLKG 480

FLDRLLVRDP AQRATASELL KHPFLGKAGP PASIVPLMRQ NRMR 524

Nucleotide Sequence
(FASTA)

ACCATCGTTC GGGGGAGCAA GGGTTCGAAG GATGGGGCCC TCACGCTGCT GTTGGATGAG 60

TTTGAGAACA TGTCTGTGAC CCGCTCCAAC TCCCTACGGC GGGATAGCCC TCCCCCGCCC 120

GCTCCCCCTC ACCAAGAGAA TGGGCTGACT GAGCCAAGGG ACAGGGGGTC GTGTCTGGGC 180

CCAGGAGAAG CAGAGGGTCG GAGTCGAGCA GCTGAGCGCA GGGACCATGG TGGCAGCAGC 240

GAGGCTAAGC GGGATGGGAT GGAGAAGAGG CCCAAGTCAT CAGGGGAGGG AGCTTTGGGT 300

CCCAGGGAGC CCTCCCGGGA CAAACGACCC CTGTCGGGGC CTGACGTCCG GACCCCACGG 360

CCCCCAGGTC CAGGAGGTGG GGCGAAGTCA TCGGCCAGCA GGCCATTTAA CACATATCCA 420

CGCGCTGACT CGGACCACCC CCCAAGGGGC ACAGGGCCCC AGGGAGAGCC CCATAATCCT 480

GCCCCTAATG GTCCCTCCAC AGGAGGCCTC CCTCCACACT CCTCCACCAA GCCGCTGCCC 540

CGTGCCTCCC GGGGCCCAGA ACCTGCCCTT GCCCCAGGGA CCTTGAGCCC CCATGCTTCA 600

GAACCCCAAC TGGCCTCACG TGCTCCCCCC TCCTTCGGCC CAGCCAGCCA TGCCCCCTCT 660

GGACCCCGCT CACCCCAAAG GGAGCCCCAG AGAGTGTCCC ATGAACAGTT CCGAGCTGCA 720

TTGCAGCTTG TGGTGGACCC AGGTGACCCC CGATCCTACC TGGACAACTT CATCAAGATC 780

GGCGAGGGTT CCACAGGCAT CGTGTGTATC GCCACGGTCC GAAGCAGTGG CAAGCTTGTT 840

GCCGTGAAGA AGATGGACCT TCGGAAGCAG CAGCGGCGAG AGCTGCTCTT CAATGAGGTG 900

GTCATCATGC GAGATTACCA GCACGAGAAT GTAGTGGAAA TGTACAACAG CTACCTGGTT 960

GGGGATGAAC TCTGGGTGGT CATGGAGTTC TTGGAAGGGG GAGCCCTCAC GGATATCGTC 1020

ACCCACACCA GGATGAATGA AGAACAAATT GCCGCCGTGT GCCTTGCTGT CCTGAAGGCT 1080

CTGTCTGTGC TCCATGCTCA GGGCGTGATC CACCGCGACA TCAAAAGTGA CTCCATCCTG 1140

CTGACCCATG ATGGGCGGGT GAAGCTCTCT GACTTTGGCT TCTGCGCCCA GGTGAACAAG 1200

GAAGTGCCCA GGAGGAAGTC CCTGGTGGGC ACTCCCTACT GGATGGCTCC TGAGCTCATC 1260

TCCCGCTTGC CCTATGGCCC TGAGGTGGAC ATATGGTCCC TAGGAGTGAT GGTCATTGAG 1320

ATGGTAGATG GGGAGCCCCC GTATTTCAAT GAGCCACCCC TGAAAGCCAT GAAGATGATT 1380

CGGGACAACC TGCCCCCTAA GCTGAAAAAC CTGCACAAGG TTTCCCCATC CCTGAAGGGC 1440

TTCCTGGATC GCCTGCTGGT GCGGGACCCG GCGCAGAGAG CCACAGCCAG TGAACTGTTG 1500

AAGCACCCCT TTCTGGGCAA GGCGGGGCCC CCAGCCAGCA TCGTCCCCCT CATGCGTCAG 1560

AATCGCATGA GATGA 1575

Domain Profile

S: 5     eeigkGalgkvylarekktgelvaikkinlekqekleelqkeisvlkklkhpniveyles  64

          +ig+G++g v++a+ +++g+lva+kk++l+kq++ e+l++e+ ++++++h+n+ve+++s

Q: 258   IKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNS  317

         68**********************************************************

S: 65    flkeeelwlvmeylagGslsdlvkeelkselkEeqiayilrevlkaLeylHskkviHrdi  124

         +l+ +elw+vme+l+gG+l+d+v+   +++++Eeqia+++  vlkaL+ lH+++viHrdi

Q: 318   YLVGDELWVVMEFLEGGALTDIVT---HTRMNEEQIAAVCLAVLKALSVLHAQGVIHRDI  374

         ************************...9********************************

S: 125   kakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaqeekgYdekaDiw  184

         k+++iLlt++g+VkLsdfg++aq++k++ +rk++vgtpywmAPE+i+  +  Y  ++Diw

Q: 375   KSDSILLTHDGRVKLSDFGFCAQVNKEVPRRKSLVGTPYWMAPELIS--RLPYGPEVDIW  432

         ***********************************************..9**********

S: 185   slGItaielaegepPfkdleplkallkilkneppklkskkkfskefkefvekclqknpek  244

         slG+++ie+++gepP+++++plka+ +i +n ppklk+ +k+s+++k f++++l ++p++

Q: 433   SLGVMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPKLKNLHKVSPSLKGFLDRLLVRDPAQ  492

         ************************************************************

S: 245   RpsasellkhkFl  257

         R++asellkh+Fl

Q: 493   RATASELLKHPFL  505

         ************7

Domain Sequence
(FASTA)

IKIGEGSTGI VCIATVRSSG KLVAVKKMDL RKQQRRELLF NEVVIMRDYQ HENVVEMYNS 60

YLVGDELWVV MEFLEGGALT DIVTHTRMNE EQIAAVCLAV LKALSVLHAQ GVIHRDIKSD 120

SILLTHDGRV KLSDFGFCAQ VNKEVPRRKS LVGTPYWMAP ELISRLPYGP EVDIWSLGVM 180

VIEMVDGEPP YFNEPPLKAM KMIRDNLPPK LKNLHKVSPS LKGFLDRLLV RDPAQRATAS 240

ELLKHPFL 248

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>