EKS-MAE-00046

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MAE-00046

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE11	350.8	4.2E-105	631	887	257

Status

Unreviewed

Ensembl Protein

ENSMEUP00000009497

Gene Name

MAP3K6

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMEUG00000010390	ENSMEUP00000009497	ENSMEUT00000010441

Organism

Macropus eugenii

Protein Length

1257

Protein Sequence
(FASTA)

MAGPGQRGRE RAGSCWQDPL AMALSSPRPP AAGRGWGRSR PLSVVYVLTR EPEAEAEPLP 60

LRCLRDACVQ LPGPRPAPQL RTLPFGTVEL GESAALDSFY NADVVVLEVS GSLGQPSLFY 120

HLGVRESFSM NNNILLCAQA DLPDLQALRE DVFQKNADCV GGYTFIPYMV TGQGRVLCGD 180

AGVMKGLAEG LFQSGAGTEA LLTPLVGRLV RLLEAIPTNS CGYFRETMRR DIRRARERFS 240

GDQLRHELGR LQRRLDSVEL LTPDIIMTLL LSYRDVQDYG AIISLVETLQ ALPTCDVAEQ 300

PNICFHYTFA LNQRNRPGDR DKALSVLLPL VRSGAVAPDL YCMCGRIYKD LFNSSGFTDT 360

SHRDQACHWY RKAFETEPSL HSGINAAVLL IAAGHQFENS DELRQIGLKL GCLLGRKGSV 420

EKMQYYWDVG FYLGAQILAN DPIQVALAAE QLYKLNAPLW YLASVMETFL LYQHFHPAPQ 480

PSGGPSGPFW LRFLLQSCQP FAAYAQYGGC VVLILEQNRV LQPARLQVRG APVAVTLSLL 540

ESEAEGIPSG WTFPAASIRG VSISKRDERC CFLYVFHTAQ DFQLGFPSHH HCQWFCKWIQ 600

TFLTQTVPLG DEGIATKEVL EFDYEYTETG ERLVLGKGTY GVVYAGRDRS TQVRIAIKEI 660

PERDSRFSQP LHEEIALHKR LRHKNIVQYL GSISQGGFLK IFMEEVPGGS LSSLLRAVWG 720

PLQDNESTIS FYTRQILQGL SYLHDNHIIH RDIKGDNVLI NTYSGLLKIS DFGTSKRLAG 780

ITPCTETFTG TLQYMAPEII DQGPRGYGKA ADIWSLGCTV IEMATGRPPF HELGNPQAAM 840

FQVGMYKIHP PVPSAMSEKA RAFILRTFEP EPKHRASAAA LLGDPFLQPR RKSRNSMSPH 900

HPHHPTGLPP ISLASSAGQS QTVPCPSANP QTSPMPPKRC FSEGGASNSQ LRVPKESVTE 960

QTLSPEENPQ RSLMRKENER RAMLERVLSQ ELSTIVESLQ WALEQVGGAR LSREQVAQLV 1020

RGLQGYICSS SRRQLAQELR ALQEQLQAQG HSLALLQGPL FAFQDAVKRV LRRHEIRPHW 1080

MFALDGLMNR AVRAALAVLG TDLKKPATGE PEDGSEEEEP EPSRGQEEPK APEEDSLPLL 1140

AQLSLLRAET GRLLGQLAEK ERQCQALALR ALQHVETSAL TLGSGPADAP PASPGDLELA 1200

QWLQQLGVDS GTIQTLLSHG FTLHMLITCA SRDDLVYTRI RGGMVCRIWR AILAQRA 1257

Nucleotide Sequence
(FASTA)

ATGGCAGGCC CTGGCCAGCG GGGGCGGGAG CGCGCTGGCA GCTGCTGGCA GGACCCGCTG 60

GCTATGGCGC TGAGCTCCCC GCGGCCGCCG GCCGCTGGCC GGGGCTGGGG CCGGAGTCGA 120

CCGCTCAGCG TGGTCTACGT GTTGACCCGG GAGCCCGAGG CCGAGGCCGA GCCGCTGCCC 180

CTGCGCTGCC TGCGCGACGC TTGCGTCCAG CTCCCCGGGC CGCGCCCGGC GCCGCAGCTG 240

CGCACGCTGC CTTTTGGGAC AGTGGAGCTG GGCGAGTCTG CCGCCTTGGA CTCTTTCTAC 300

AACGCGGATG TGGTTGTGCT GGAAGTGAGT GGCTCCCTGG GCCAGCCCTC CCTGTTCTAC 360

CACCTCGGAG TGAGGGAGAG TTTTAGCATG AACAACAACA TTCTTCTCTG TGCCCAAGCA 420

GACCTGCCTG ACCTACAGGC CCTCAGGGAA GATGTCTTTC AGAAAAATGC CGATTGCGTT 480

GGGGGCTACA CTTTCATCCC CTACATGGTG ACTGGCCAAG GACGGGTCCT GTGTGGCGAT 540

GCAGGTGTTA TGAAGGGGCT GGCAGAAGGG CTGTTCCAGT CGGGAGCAGG CACTGAGGCC 600

CTCCTCACCC CGCTGGTGGG CAGGCTTGTC CGCCTGCTGG AGGCTATACC CACCAATTCC 660

TGTGGCTACT TCCGAGAGAC TATGCGGAGG GACATCCGCC GAGCCCGGGA GCGCTTCTCT 720

GGGGACCAGC TTCGTCATGA GTTGGGCCGG CTACAGCGAC GGCTGGACAG TGTGGAGCTG 780

CTGACCCCTG ACATCATCAT GACCCTGCTG CTCTCTTACC GGGATGTGCA GGACTATGGG 840

GCCATCATCT CCCTGGTGGA GACGCTGCAG GCCCTGCCCA CCTGTGATGT GGCTGAGCAG 900

CCCAACATCT GTTTTCACTA CACCTTCGCC CTGAACCAGA GGAACAGGCC TGGCGACCGA 960

GACAAGGCCC TATCTGTGCT GTTGCCCCTA GTGCGTAGTG GGGCTGTGGC TCCCGACCTC 1020

TACTGCATGT GTGGCCGAAT CTACAAGGAC TTGTTTAACA GCTCAGGCTT CACTGACACT 1080

AGTCACCGAG ACCAAGCTTG TCACTGGTAC CGAAAGGCCT TTGAGACGGA ACCCAGCCTT 1140

CACTCAGGCA TAAACGCAGC TGTCCTTCTC ATAGCCGCTG GACACCAGTT TGAAAACTCA 1200

GATGAGCTCC GGCAGATAGG ACTGAAGTTG GGATGCCTGC TGGGCCGCAA GGGCAGTGTG 1260

GAGAAGATGC AGTATTACTG GGACGTGGGC TTCTACCTGG GAGCCCAGAT CCTTGCCAAT 1320

GACCCCATCC AGGTGGCTCT GGCTGCTGAG CAGCTCTACA AGCTGAATGC TCCCCTCTGG 1380

TACCTGGCCT CAGTGATGGA GACCTTCCTT CTTTACCAGC ATTTCCACCC AGCCCCCCAG 1440

CCCTCAGGAG GGCCTTCGGG CCCTTTCTGG CTCCGATTCC TCCTACAATC TTGCCAGCCC 1500

TTTGCTGCCT ATGCCCAGTA TGGAGGATGC GTAGTGCTGA TCCTGGAGCA GAATAGGGTG 1560

CTGCAGCCTG CCAGGCTTCA GGTGCGGGGA GCCCCAGTAG CCGTGACCTT GAGCCTGCTG 1620

GAGTCTGAGG CAGAGGGGAT TCCCTCTGGC TGGACCTTCC CCGCGGCCTC CATCCGGGGA 1680

GTCAGCATCT CGAAGAGAGA CGAGCGCTGT TGCTTTCTGT ATGTGTTCCA CACCGCCCAG 1740

GACTTCCAGC TGGGCTTCCC TAGTCACCAT CACTGCCAGT GGTTCTGTAA GTGGATCCAG 1800

ACCTTCCTGA CTCAGACAGT GCCTCTTGGA GATGAGGGCA TAGCCACCAA GGAGGTGTTG 1860

GAGTTTGACT ATGAGTACAC AGAGACAGGA GAGCGGCTGG TCCTGGGCAA AGGTACCTAT 1920

GGGGTGGTGT ATGCTGGTCG GGATCGCAGC ACCCAGGTAC GGATCGCCAT CAAGGAGATC 1980

CCTGAGAGAG ACAGCAGGTT TTCCCAGCCC CTCCATGAAG AAATTGCCCT GCACAAACGT 2040

TTACGCCATA AGAATATTGT CCAGTACCTG GGGTCTATCA GCCAGGGTGG TTTCCTCAAG 2100

ATTTTCATGG AGGAGGTACC TGGAGGCAGC CTATCATCCT TGTTGCGGGC TGTGTGGGGA 2160

CCACTTCAGG ACAACGAAAG CACCATCAGC TTCTACACTC GGCAGATCCT ACAGGGTCTG 2220

AGCTATCTCC ATGACAACCA CATCATACAC CGCGACATCA AGGGGGACAA CGTACTGATC 2280

AATACATACA GTGGTCTGCT GAAAATCTCT GACTTTGGCA CTTCCAAGAG GCTGGCGGGC 2340

ATCACCCCCT GTACAGAGAC TTTCACAGGA ACCCTGCAAT ACATGGCTCC TGAGATCATT 2400

GACCAAGGCC CCCGGGGCTA TGGAAAGGCA GCCGACATTT GGTCCCTGGG CTGCACTGTC 2460

ATTGAAATGG CCACTGGACG TCCACCTTTC CATGAGCTAG GCAATCCCCA GGCTGCCATG 2520

TTCCAGGTGG GTATGTACAA GATCCATCCA CCAGTGCCTA GCGCCATGTC CGAGAAGGCC 2580

CGAGCCTTCA TCCTACGCAC CTTTGAGCCC GAGCCTAAGC ACCGTGCCAG TGCTGCTGCC 2640

CTGCTGGGTG ACCCTTTCTT GCAACCTCGG CGTAAATCCC GAAACTCCAT GTCACCGCAT 2700

CACCCCCATC ACCCTACAGG TCTCCCACCG ATCAGTCTAG CTTCCTCAGC TGGCCAGTCA 2760

CAGACAGTGC CATGCCCAAG TGCCAATCCC CAGACCAGCC CCATGCCCCC CAAGCGCTGC 2820

TTCAGTGAAG GAGGAGCCTC TAATAGCCAG CTACGGGTGC CCAAGGAGTC TGTCACAGAG 2880

CAGACCTTAT CCCCAGAGGA GAACCCACAG CGGTCTCTGA TGCGTAAGGA GAATGAGCGG 2940

AGGGCCATGC TGGAGCGAGT ACTCAGCCAG GAGCTGTCCA CCATAGTGGA GAGCCTGCAG 3000

TGGGCTCTGG AGCAGGTGGG CGGGGCCCGC CTGAGCCGGG AGCAGGTGGC CCAGCTGGTG 3060

AGAGGTCTCC AAGGCTACAT CTGTTCTTCC AGTCGCCGAC AGCTGGCACA GGAACTTCGG 3120

GCCCTGCAAG AGCAGCTTCA GGCCCAGGGG CACAGCTTGG CATTACTCCA GGGTCCCCTC 3180

TTTGCTTTCC AGGATGCTGT GAAACGGGTC CTCCGAAGGC ATGAAATCCG GCCCCACTGG 3240

ATGTTTGCCC TGGATGGACT GATGAACCGG GCAGTAAGGG CAGCCCTGGC TGTGCTGGGG 3300

ACAGATCTAA AGAAGCCAGC CACAGGGGAG CCTGAAGATG GGAGCGAGGA AGAGGAGCCA 3360

GAACCGAGCA GAGGCCAGGA GGAGCCAAAG GCTCCTGAAG AGGATTCCCT ACCCCTACTG 3420

GCACAGCTGA GCCTCCTAAG GGCAGAGACA GGCAGGCTCC TAGGACAGCT AGCAGAGAAG 3480

GAGAGGCAAT GCCAGGCATT AGCTCTCAGG GCACTGCAGC ATGTAGAGAC CTCTGCTCTA 3540

ACCTTAGGTT CTGGGCCTGC AGATGCCCCA CCAGCCTCCC CAGGGGACCT GGAGCTGGCC 3600

CAGTGGCTGC AGCAGCTGGG TGTGGATTCA GGCACCATCC AGACACTCCT GAGTCACGGC 3660

TTCACTTTGC ACATGCTCAT CACTTGTGCC AGTCGAGATG ACCTTGTCTA TACTCGGATC 3720

AGGGGTGGAA TGGTGTGCCG GATCTGGAGA GCCATCCTGG CACAGCGGGC A 3771

Domain Profile

S: 3     krevigkGsfgsvyaaldvdtgellavKeveikpekksekkevkalkeEikllkelkHen  62

         +r v+gkG++g vya++d +t+ ++a+Ke+   pe++s+   +++l+eEi+l+k+l+H+n

Q: 631   ERLVLGKGTYGVVYAGRDRSTQVRIAIKEI---PERDSR--FSQPLHEEIALHKRLRHKN  685

         5779**************************...888775..9******************

S: 63    ivkyyGveveeeelkiflEyvegGslsslle.kygkle..esvikkytkqileglayLHe  119

         iv+y+G+ ++ + lkif+E v+gGslssll+  +g+l+  es+i++yt+qil+gl+yLH+

Q: 686   IVQYLGSISQGGFLKIFMEEVPGGSLSSLLRaVWGPLQdnESTISFYTRQILQGLSYLHD  745

         *******************************99****9999*******************

S: 120   kkivHRDiKgaNillds.sgvvklsDFGaskrlaelntkaaelesltGtlaymaPEvikk  178

         ++i+HRDiKg+N+l+++ sg++k+sDFG+skrla ++++   +e++tGtl+ymaPE+i++

Q: 746   NHIIHRDIKGDNVLINTySGLLKISDFGTSKRLAGITPC---TETFTGTLQYMAPEIIDQ  802

         ***************************************...8*****************

S: 179   kekgygrkaDiWslgcvviemltgkrPfaeldeelaimfkvgakktkPeipeklseegkd  238

         + +gyg++aDiWslgc+viem+tg++Pf+el++++a+mf+vg+ k++P++p+++se++++

Q: 803   GPRGYGKAADIWSLGCTVIEMATGRPPFHELGNPQAAMFQVGMYKIHPPVPSAMSEKARA  862

         ************************************************************

S: 239   flekcleldpkkrpsaeeLLkhefl  263

         f+ +++e +pk+r+sa+ LL ++fl

Q: 863   FILRTFEPEPKHRASAAALLGDPFL  887

         **********************996

Domain Sequence
(FASTA)

ERLVLGKGTY GVVYAGRDRS TQVRIAIKEI PERDSRFSQP LHEEIALHKR LRHKNIVQYL 60

GSISQGGFLK IFMEEVPGGS LSSLLRAVWG PLQDNESTIS FYTRQILQGL SYLHDNHIIH 120

RDIKGDNVLI NTYSGLLKIS DFGTSKRLAG ITPCTETFTG TLQYMAPEII DQGPRGYGKA 180

ADIWSLGCTV IEMATGRPPF HELGNPQAAM FQVGMYKIHP PVPSAMSEKA RAFILRTFEP 240

EPKHRASAAA LLGDPFL 257

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>