EKS-MEG-00356

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MEG-00356

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	526.2	1.3E-158	36	293	258

Status

Unreviewed

Ensembl Protein

ENSMGAP00000002756

UniProt Accession

G1MVQ9;

Protein Name

Protein Synonyms/Alias

Gene Name

SGK2

Gene Synonyms/Alias

SGK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMGAG00000003077	ENSMGAP00000002756	ENSMGAT00000003441

Organism

Meleagris gallopavo

Functional Description

Protein Length

365

Protein Sequence
(FASTA)

HLRAVLGVPC PEQPTTPTDN INLGPSANPN AKPTDFDFLK VIGKGSFGKV LLAKRKCDGT 60

FYAVKVLHKK TILKKKEQNH IMAERNVLLK NVKHPFLVGL HYSFQTSEKL YFVLDYVNGG 120

ELFFHLQRER CFREPRARFY AAEVASAIGY LHSLNIIYRD LKPENILLDC QGHVVLTDFG 180

LCKEGMEEEE TTSTFCGTPE YLAPEVLKKQ PYDRTVDWWC LGAVLYEMLF GLPPFYSRDV 240

SQMYDNILHK QLQIQGSKTV AACDILHGLL HKDQKRRLGA KTDFLEIKNH VFFSPINWDD 300

LYHKRITPPF NPNVAGPSDL RHFDPEFTQE AISASITHTP DLAASSSSAS DAFLGFSYAP 360

TEEDF 365

Nucleotide Sequence
(FASTA)

CATCTCAGAG CAGTGCTGGG AGTTCCCTGC CCAGAGCAGC CTACAACACC AACTGACAAC 60

ATCAACCTTG GACCTTCTGC TAACCCAAAT GCCAAGCCAA CAGACTTTGA CTTCTTGAAG 120

GTTATTGGCA AAGGAAGCTT TGGAAAAGTT CTCCTGGCCA AACGCAAGTG TGATGGGACT 180

TTTTATGCTG TGAAAGTCTT GCATAAGAAA ACCATCCTAA AGAAAAAGGA GCAAAACCAC 240

ATCATGGCAG AACGCAACGT GCTTCTGAAA AATGTCAAGC ACCCCTTCCT GGTGGGCCTC 300

CATTACTCCT TCCAGACCTC GGAGAAGCTT TACTTTGTGC TTGATTATGT AAATGGGGGA 360

GAGCTCTTCT TCCACTTGCA AAGAGAGCGT TGTTTCCGTG AGCCCCGTGC AAGATTCTAT 420

GCTGCAGAAG TTGCTAGTGC AATTGGTTAC CTGCATTCCT TAAACATCAT CTATAGGGAT 480

TTAAAACCTG AGAACATCCT CCTGGATTGC CAGGGACATG TGGTGTTGAC AGATTTTGGA 540

CTCTGCAAGG AAGGAATGGA GGAAGAGGAG ACTACCTCTA CGTTTTGTGG CACTCCTGAG 600

TACTTAGCTC CTGAGGTGCT AAAGAAGCAG CCGTATGACA GGACAGTAGA CTGGTGGTGC 660

CTTGGAGCTG TCCTCTATGA GATGCTTTTT GGACTGCCTC CCTTTTATAG CCGGGATGTG 720

TCTCAGATGT ATGACAACAT TCTCCACAAG CAACTCCAGA TCCAAGGAAG CAAGACTGTG 780

GCAGCCTGTG ATATCCTCCA TGGACTTCTC CACAAGGACC AGAAGAGGAG GCTGGGTGCC 840

AAAACAGACT TTCTTGAGAT AAAGAACCAC GTATTCTTCA GCCCAATAAA CTGGGATGAC 900

TTGTACCACA AGAGGATTAC CCCTCCATTC AACCCTAATG TGGCTGGCCC ATCTGATCTG 960

CGGCACTTTG ACCCAGAATT CACCCAGGAA GCCATCTCTG CCTCCATCAC CCACACACCT 1020

GACTTAGCAG CCAGCAGCTC CAGTGCCTCA GATGCATTTT TAGGATTTTC TTATGCACCA 1080

ACTGAAGAGG ACTTCTAG 1098

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         fdflkvigkgsfgkvllakrk d++fyavkvl+kk+ilkkke++himaernvllknvkhp

Q: 36    FDFLKVIGKGSFGKVLLAKRKCDGTFYAVKVLHKKTILKKKEQNHIMAERNVLLKNVKHP  95

         9***********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flvglhysfqt+eklyfvldyvnggelffhlqrer+f eprarfyaae+asa+gylhsln

Q: 96    FLVGLHYSFQTSEKLYFVLDYVNGGELFFHLQRERCFREPRARFYAAEVASAIGYLHSLN  155

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpydrt  180

         i+yrdlkpenilld++ghvvltdfglcke++e+e+ttstfcgtpeylapevl+k+pydrt

Q: 156   IIYRDLKPENILLDCQGHVVLTDFGLCKEGMEEEETTSTFCGTPEYLAPEVLKKQPYDRT  215

         ************************************************************

S: 181   vdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekdrk  240

         vdwwclgavlyeml+glppfysrdv++mydnil+k lq++++ +vaa+++l++ll+kd+k

Q: 216   VDWWCLGAVLYEMLFGLPPFYSRDVSQMYDNILHKQLQIQGSKTVAACDILHGLLHKDQK  275

         ************************************************************

S: 241   krlgakedfleiknhvff  258

         +rlgak dfleiknhvff

Q: 276   RRLGAKTDFLEIKNHVFF  293

         *****************9

Domain Sequence
(FASTA)

FDFLKVIGKG SFGKVLLAKR KCDGTFYAVK VLHKKTILKK KEQNHIMAER NVLLKNVKHP 60

FLVGLHYSFQ TSEKLYFVLD YVNGGELFFH LQRERCFREP RARFYAAEVA SAIGYLHSLN 120

IIYRDLKPEN ILLDCQGHVV LTDFGLCKEG MEEEETTSTF CGTPEYLAPE VLKKQPYDRT 180

VDWWCLGAVL YEMLFGLPPF YSRDVSQMYD NILHKQLQIQ GSKTVAACDI LHGLLHKDQK 240

RRLGAKTDFL EIKNHVFF 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0015459	; F:potassium channel regulator activity
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013