EKS-MEG-00343

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MEG-00343

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/DAPK	445.7	3.7E-134	20	275	256

Status

Unreviewed

Ensembl Protein

ENSMGAP00000002211

UniProt Accession

G1MUJ5;

Protein Name

Protein Synonyms/Alias

Gene Name

DAPK2

Gene Synonyms/Alias

DAPK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMGAG00000003962	ENSMGAP00000002211	ENSMGAT00000002886
ENSMGAG00000003962	ENSMGAP00000003753	ENSMGAT00000004460

Organism

Meleagris gallopavo

Functional Description

Protein Length

452

Protein Sequence
(FASTA)

LTGIQMEEVD NFSFHSDSSA NGQFAIVKKC REISTGLEYA AKFIKKRQSR ASRRGVRREE 60

IEREVDILQQ TLHANIIKLH DIYENKTDVV LILELVSGGE LFDFLAQKES LSEEEATRFI 120

KQILDGVNYL HSKKIAHFDL KPENIMLLDK NIPIPHIKLI DFGLAHKIED GVEFKNIFGT 180

PEFVGEEIVN YEPLGLAADM WSIGVITYIL LSGASPFLGE TKQETLANIT AVNYEFDEEF 240

FSNTSDLAKD FIRKLLVKDT RKRLTIQEAL SHPWITTHQL KEETKVEENK KAENTQLKTK 300

RLREYTIKCH SSMPPNNTYI NFERFAQVVE DISCMEREVS ALAASHDSLQ EDIDALVSIY 360

NEKEAWYKEE NESVRHKLSQ LKYEFRKTES LKRHLQDDIK TVGASLTVMT GKYAALQSQY 420

ESLSQELSED LKWIQDLIKT LPRTETEILM CC 452

Nucleotide Sequence
(FASTA)

TTAACTGGTA TCCAAATGGA AGAGGTAGAC AACTTTTCCT TCCATTCAGA CTCTTCAGCA 60

AATGGCCAAT TTGCTATTGT GAAGAAATGT AGAGAAATAA GCACCGGTTT GGAGTATGCT 120

GCTAAGTTCA TTAAAAAGCG TCAGAGTCGG GCCAGCCGTC GTGGGGTGAG GCGTGAGGAA 180

ATAGAACGGG AGGTGGACAT TCTGCAGCAG ACCCTACATG CCAACATCAT CAAGCTTCAC 240

GACATCTATG AGAACAAGAC GGATGTGGTT CTCATCCTTG AGCTGGTGTC TGGAGGAGAA 300

CTTTTTGACT TCCTGGCACA GAAGGAATCT TTGAGTGAGG AGGAAGCAAC CAGATTCATC 360

AAGCAGATTT TGGATGGTGT GAATTACCTT CACTCTAAGA AAATTGCTCA CTTTGATTTA 420

AAGCCTGAAA ACATTATGCT TCTTGACAAG AATATCCCTA TTCCACACAT CAAACTCATT 480

GATTTTGGCC TGGCTCACAA AATAGAAGAT GGAGTTGAAT TTAAAAACAT TTTTGGAACT 540

CCGGAATTCG TAGGTGAAGA AATAGTGAAC TATGAACCAC TGGGGCTGGC TGCAGATATG 600

TGGAGCATAG GAGTCATCAC CTACATACTG CTTAGTGGTG CATCACCTTT CCTTGGAGAA 660

ACTAAACAAG AAACGCTCGC TAACATCACA GCTGTGAATT ATGAATTCGA TGAAGAATTT 720

TTCAGCAATA CCAGTGACCT GGCAAAAGAT TTTATTCGGA AACTCCTGGT GAAAGATACA 780

CGGAAACGTC TTACAATTCA AGAAGCTCTG TCTCATCCGT GGATAACGAC TCACCAGCTG 840

AAGGAAGAAA CAAAAGTCGA AGAAAACAAG AAGGCTGAGA ACACACAGCT CAAGACAAAA 900

CGACTGAGAG AGTACACCAT AAAATGCCAT TCAAGTATGC CTCCTAATAA CACCTACATC 960

AACTTTGAGC GCTTTGCCCA GGTAGTAGAA GACATTTCAT GTATGGAACG AGAGGTCAGT 1020

GCTTTGGCTG CATCCCACGA TTCTTTGCAG GAGGACATTG ATGCTCTGGT TTCCATTTAT 1080

AATGAAAAAG AAGCTTGGTA TAAAGAAGAA AATGAAAGTG TGAGGCATAA GCTGTCTCAG 1140

CTCAAGTATG AATTCCGTAA AACTGAATCC CTGAAAAGAC ATCTACAAGA TGATATCAAG 1200

ACTGTAGGTG CCAGTCTTAC AGTCATGACT GGGAAATATG CTGCTCTGCA GAGTCAGTAT 1260

GAATCTCTCA GTCAAGAGCT TTCTGAGGAT CTTAAGTGGA TACAGGATTT GATAAAAACA 1320

TTACCTAGAA CTGAAACAGA AATTCTGATG TGTTGC 1356

Domain Profile

S: 8     gsGkfavvrkcrekstGkeyaakflkkrrlkssrrgvsreeierevavlkeirsepnvin  67

          +G+fa+v+kcre stG eyaakf+kkr++++srrgv reeierev +l++   + n+i+

Q: 20    ANGQFAIVKKCREISTGLEYAAKFIKKRQSRASRRGVRREEIEREVDILQQTL-HANIIK  78

         57**************************************************9.******

S: 68    lhevyenksdvililelvaGGelfdllaekeslseeeatellkqilegvkylhskkivhl  127

         lh++yenk+dv+lilelv+GGelfd+la+keslseeeat+++kqil+gv+ylhskki+h+

Q: 79    LHDIYENKTDVVLILELVSGGELFDFLAQKESLSEEEATRFIKQILDGVNYLHSKKIAHF  138

         ************************************************************

S: 128   dlkPenillldkkvpkgdiklidfGlsrkieegaelkeilGtPefvaPeivnyeplslet  187

         dlkPeni+lldk++p ++iklidfGl++kie+g+e+k+i+GtPefv  eivnyepl+l++

Q: 139   DLKPENIMLLDKNIPIPHIKLIDFGLAHKIEDGVEFKNIFGTPEFVGEEIVNYEPLGLAA  198

         ************************************************************

S: 188   dmwsiGvityillsgasPflGdtkqetllnisavnldfseelfssvselakdfirrllvk  247

         dmwsiGvityillsgasPflG+tkqetl+ni+avn++f+ee+fs++s+lakdfir+llvk

Q: 199   DMWSIGVITYILLSGASPFLGETKQETLANITAVNYEFDEEFFSNTSDLAKDFIRKLLVK  258

         ************************************************************

S: 248   dpekrltieeclehswl  264

         d++krlti+e+l+h+w+

Q: 259   DTRKRLTIQEALSHPWI  275

         ****************8

Domain Sequence
(FASTA)

ANGQFAIVKK CREISTGLEY AAKFIKKRQS RASRRGVRRE EIEREVDILQ QTLHANIIKL 60

HDIYENKTDV VLILELVSGG ELFDFLAQKE SLSEEEATRF IKQILDGVNY LHSKKIAHFD 120

LKPENIMLLD KNIPIPHIKL IDFGLAHKIE DGVEFKNIFG TPEFVGEEIV NYEPLGLAAD 180

MWSIGVITYI LLSGASPFLG ETKQETLANI TAVNYEFDEE FFSNTSDLAK DFIRKLLVKD 240

TRKRLTIQEA LSHPWI 256

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0043276	; P:anoikis
GO:0006917	; P:induction of apoptosis
GO:0007243	; P:intracellular protein kinase cascade

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR020675	; Myosin_light_ch_kinase-rel.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013