EKS-MEG-00123

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MEG-00123

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/RSK	344.0	5.1E-103	66	325	260

Status

Unreviewed

Ensembl Protein

ENSMGAP00000004220

UniProt Accession

H9H0P4;

Protein Name

Protein Synonyms/Alias

Gene Name

RPS6KB2

Gene Synonyms/Alias

RPS6KB2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMGAG00000004389	ENSMGAP00000004220	ENSMGAT00000004933

Organism

Meleagris gallopavo

Functional Description

Protein Length

433

Protein Sequence
(FASTA)

MAGVFDIDLE TEEGSDGEES ELGAVSPPGT SGPWGETARG QRHYEEIEIS ENSVNNGPEQ 60

IGPHCFELLR VLGKGGYGKV FQVRKVQGTN TGKIFAMKVL KKAKIACSAK DTAHTRAERN 120

ILEAIKHPFI VDLIYAFQTG GKLYLILECL SGGELFMQLE REGIFLEDTA CFYLSEITLA 180

LGHLHSNGII YRDLKPIMLN SQGHIKLTDF GLCKESIHDG AVTHTFCGTI EYMAPEILVH 240

SGHNRAVDWW SLGALMYDML TGSPPFTAEN RKKTIDKILK GKLVLPPYLT PDARDLLKKF 300

LKRNPSQRIG GGPGDAADVQ KHPFFRHINW EELLARHLDP PFKPCLQSEE DVSQFDVRFT 360

RQTPVDSPDD AIISESANQA FLGFTYVAPV LESIKEGFSF QPKVRSPAAS TAAPTPPRQV 420

PRARFGGHYG KAA 433

Nucleotide Sequence
(FASTA)

ATGGCGGGGG TGTTCGACAT CGACCTGGAG ACCGAGGAGG GAAGCGACGG GGAAGAGTCC 60

GAGCTGGGCG CCGTGAGTCC ACCGGGGACG TCGGGACCTT GGGGGGAGAC GGCGCGGGGA 120

CAGCGGCACT ACGAGGAGAT AGAAATCTCA GAGAACAGCG TCAACAACGG CCCGGAGCAA 180

ATCGGGCCCC ACTGCTTCGA GCTGCTGCGC GTCCTGGGCA AGGGCGGCTA TGGCAAGGTC 240

TTCCAGGTGC GCAAGGTACA GGGCACCAAC ACAGGGAAGA TCTTCGCCAT GAAGGTGCTG 300

AAGAAGGCCA AGATTGCCTG CAGTGCCAAG GACACAGCGC ACACGCGGGC TGAGAGAAAC 360

ATCCTGGAGG CCATCAAACA CCCCTTCATC GTTGACCTCA TCTATGCCTT CCAGACGGGC 420

GGCAAGCTCT ACCTCATCCT GGAGTGCCTC AGTGGTGGGG AGCTCTTCAT GCAGCTGGAG 480

CGTGAGGGCA TCTTCCTGGA AGACACCGCC TGCTTTTATC TCAGTGAGAT CACACTGGCG 540

CTGGGCCACC TGCACTCTAA CGGCATCATC TACCGTGATC TCAAGCCAAT CATGCTCAAC 600

AGCCAGGGTC ACATCAAGCT TACAGACTTC GGTCTCTGCA AGGAGTCCAT CCATGATGGA 660

GCAGTCACCC ACACCTTCTG CGGCACTATC GAGTACATGG CCCCGGAGAT TCTGGTGCAC 720

AGTGGGCACA ACCGCGCAGT GGACTGGTGG AGCCTGGGTG CCCTGATGTA TGACATGCTC 780

ACCGGATCGC CCCCATTCAC AGCAGAGAAC CGCAAGAAAA CCATTGACAA GATCCTGAAG 840

GGGAAGTTGG TGTTGCCACC CTACCTGACA CCCGATGCAC GTGACCTGCT CAAGAAGTTC 900

CTCAAGCGCA ACCCCAGCCA GCGCATTGGT GGGGGACCGG GAGATGCAGC CGATGTGCAG 960

AAGCATCCCT TCTTCCGGCA CATCAACTGG GAGGAGCTGC TGGCACGCCA CCTGGACCCT 1020

CCCTTCAAAC CCTGTTTGCA GTCGGAGGAG GATGTCAGCC AGTTCGACGT CCGCTTCACA 1080

CGCCAGACCC CCGTGGACAG CCCCGATGAT GCCATCATCA GTGAGAGTGC CAACCAGGCC 1140

TTCCTGGGCT TCACCTATGT GGCCCCCGTG CTGGAGAGTA TCAAGGAGGG CTTCTCCTTC 1200

CAGCCTAAGG TGCGCTCCCC CGCCGCCTCA ACAGCAGCCC CCACACCCCC ACGTCAGGTA 1260

CCCCGTGCCA GGTTTGGGGG GCACTACGGG AAAGCTGCC 1299

Domain Profile

S: 1     fellkvlgkGaygkvflvrkvekkdtgklyavKvlkkaelvk..kkkertkeereiLeev  58

         fell+vlgkG+ygkvf+vrkv++++tgk++a+Kvlkka+++   k++++t++er+iLe++

Q: 66    FELLRVLGKGGYGKVFQVRKVQGTNTGKIFAMKVLKKAKIACsaKDTAHTRAERNILEAI  125

         89**************************************9889****************

S: 59    ehpfivklheafqdekklylvlellkGgeLlerlkkkklfseeeasfilaelvlaleylH  118

         +hpfiv+l +afq+  klyl+le+l+GgeL+++l+++++f e++a+f+l+e++lal +lH

Q: 126   KHPFIVDLIYAFQTGGKLYLILECLSGGELFMQLEREGIFLEDTACFYLSEITLALGHLH  185

         ************************************************************

S: 119   skgvvyrDLkpeNilldeeghvkltDfglakekiaeneekaysfcgTleyvaPevlkrkg  178

         s+g++yrDLkp  i+l+++gh+kltDfgl+ke+i +++  +++fcgT+ey+aPe+l ++g

Q: 186   SNGIIYRDLKP--IMLNSQGHIKLTDFGLCKESI-HDGAVTHTFCGTIEYMAPEILVHSG  242

         **********9..********************9.9999999******************

S: 179   ydeavDlwslGvllyemLtGktPftgeerketlarilkgkfslklpaweelseeakdlvk  238

         +++avD+wslG+l+y+mLtG++Pft+e+rk+t+++ilkgk  l lp +  l+++a+dl+k

Q: 243   HNRAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGK--LVLPPY--LTPDARDLLK  298

         ****************************************..9*****..**********

S: 239   klLkkdpakRlga...taeeikehkfl  262

         k+Lk++p++R+g    +a+++++h+f+

Q: 299   KFLKRNPSQRIGGgpgDAADVQKHPFF  325

         ***********99999*********97

Domain Sequence
(FASTA)

FELLRVLGKG GYGKVFQVRK VQGTNTGKIF AMKVLKKAKI ACSAKDTAHT RAERNILEAI 60

KHPFIVDLIY AFQTGGKLYL ILECLSGGEL FMQLEREGIF LEDTACFYLS EITLALGHLH 120

SNGIIYRDLK PIMLNSQGHI KLTDFGLCKE SIHDGAVTHT FCGTIEYMAP EILVHSGHNR 180

AVDWWSLGAL MYDMLTGSPP FTAENRKKTI DKILKGKLVL PPYLTPDARD LLKKFLKRNP 240

SQRIGGGPGD AADVQKHPFF 260

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Tursiops truncatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013