EKS-MEG-00044

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MEG-00044

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	437.7	1.3E-131	4	287	284

Status

Unreviewed

Ensembl Protein

ENSMGAP00000004288

UniProt Accession

G1MZ52;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK3

Gene Synonyms/Alias

CDK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMGAG00000004451	ENSMGAP00000004288	ENSMGAT00000005002

Organism

Meleagris gallopavo

Functional Description

Protein Length

306

Protein Sequence
(FASTA)

QQVFQKVEKI GEGTYGVVYK ARNKRTGQLV ALKKIRLDAE TEGVPSTAIR EISLLKELKH 60

PNIVRLLDVV HSQKKLYLVF EYLNQDLKKY IDSSQTGEFP LSLVKNYLFQ LLQGVSFCHS 120

HRVIHRDLKP QNLLINEAGA IKLADFGLAR AFGVPLRTYT HEVVTLWYRA PEILLGCKYY 180

STAVDMWSIG CIFAEMVVTR KALFQGDSEI DQLFRIFRTL GTPTEATWPG VSQLPDYKGD 240

FPQWARKEMK EVVPNLDRHG RDLLAQLLLY DPSKRISAKA ALSHQYFFRK SPQSTEEQHV 300

HQRHCR 306

Nucleotide Sequence
(FASTA)

CAGCAGGTGT TCCAGAAGGT GGAGAAGATC GGGGAGGGCA CCTATGGTGT GGTGTACAAG 60

GCTCGCAACA AGCGCACGGG GCAGCTGGTG GCCCTCAAGA AGATCCGCTT GGACGCGGAG 120

ACAGAGGGCG TCCCCAGCAC TGCCATCCGA GAAATCTCGC TGTTGAAGGA GCTGAAGCAT 180

CCCAACATAG TCAGGCTCCT GGATGTTGTG CACAGCCAGA AGAAGTTGTA TCTCGTATTT 240

GAGTATCTCA ATCAGGACCT GAAGAAATAC ATAGACTCTT CCCAAACTGG AGAGTTTCCT 300

TTAAGCTTGG TCAAGAATTA CCTTTTCCAG CTGCTGCAGG GTGTGAGCTT TTGCCACTCT 360

CACAGAGTCA TTCACAGGGA CTTGAAGCCA CAGAACTTGC TCATTAATGA AGCAGGAGCA 420

ATCAAACTGG CTGATTTTGG GCTGGCAAGA GCTTTTGGAG TTCCCCTGCG CACATACACT 480

CATGAGGTGG TGACTTTGTG GTACCGAGCT CCTGAAATAC TCCTGGGATG CAAATACTAT 540

TCAACAGCTG TGGATATGTG GAGCATTGGC TGCATCTTTG CCGAAATGGT AGTGACCAGG 600

AAGGCCCTGT TTCAAGGGGA CTCAGAGATC GATCAGCTCT TCCGGATCTT TCGCACCCTG 660

GGCACTCCCA CCGAAGCAAC CTGGCCTGGG GTGTCACAGC TGCCTGACTA CAAGGGCGAC 720

TTTCCCCAGT GGGCAAGGAA AGAGATGAAG GAAGTTGTTC CCAACTTAGA TCGACATGGC 780

AGAGACCTAC TGGCGCAATT GCTCCTGTAC GACCCCAGCA AACGCATCTC AGCCAAGGCA 840

GCTCTCAGTC ACCAGTACTT CTTTCGGAAA AGCCCCCAGA GCACTGAAGA GCAACACGTG 900

CATCAGAGAC ACTGCAGATG A 921

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         ++k+ekigeGtyg+vyka++k+tg++vAlKkirl+ e+egvp+ta+rEisllkelkh+ni

Q: 4     FQKVEKIGEGTYGVVYKARNKRTGQLVALKKIRLDAETEGVPSTAIREISLLKELKHPNI  63

         89**********************************************************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v+Ll+vv+ ++kklyLvfe+l+qdLkk+++++++ +++l+ vk++l+qll+g++++Hs++

Q: 64    VRLLDVVH-SQKKLYLVFEYLNQDLKKYIDSSQTGEFPLSLVKNYLFQLLQGVSFCHSHR  122

         ********.99*************************************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         ++HRDlKpqNlLi++ g +klaDfGlaraf++pl+tyt+evvTlwYraPe+Llg+k+Yst

Q: 123   VIHRDLKPQNLLINEAGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGCKYYST  182

         ************************************************************

S: 181   avDiWsvgcilaell.trkplfqgkseidqlerifkllgtpsekvwpevsklpeykksfp  239

         avD+Ws+gci+ae++ trk+lfqg+seidql+rif++lgtp+e++wp+vs+lp+yk +fp

Q: 183   AVDMWSIGCIFAEMVvTRKALFQGDSEIDQLFRIFRTLGTPTEATWPGVSQLPDYKGDFP  242

         *************96489******************************************

S: 240   kkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         ++++k++ke+v++l+++++dll +ll +dp+kRisak+al+h+yf

Q: 243   QWARKEMKEVVPNLDRHGRDLLAQLLLYDPSKRISAKAALSHQYF  287

         ********************************************9

Domain Sequence
(FASTA)

FQKVEKIGEG TYGVVYKARN KRTGQLVALK KIRLDAETEG VPSTAIREIS LLKELKHPNI 60

VRLLDVVHSQ KKLYLVFEYL NQDLKKYIDS SQTGEFPLSL VKNYLFQLLQ GVSFCHSHRV 120

IHRDLKPQNL LINEAGAIKL ADFGLARAFG VPLRTYTHEV VTLWYRAPEI LLGCKYYSTA 180

VDMWSIGCIF AEMVVTRKAL FQGDSEIDQL FRIFRTLGTP TEATWPGVSQ LPDYKGDFPQ 240

WARKEMKEVV PNLDRHGRDL LAQLLLYDPS KRISAKAALS HQYF 284

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013