EPS-MEG-00031

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-MEG-00031

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	206.4	5.1E-61	649	894	246

Status

Unreviewed

Ensembl Protein

ENSMGAP00000004661

UniProt Accession

G1MZY7;

Protein Name

Protein Synonyms/Alias

Gene Name

PHLPP1

Gene Synonyms/Alias

PHLPP1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMGAG00000004804	ENSMGAP00000004661	ENSMGAT00000005382

Organism

Meleagris gallopavo

Functional Description

Protein Length

1152

Protein Sequence
(FASTA)

KPHSIGSSER IQLSGMYNVR KGKIHLPVNR WTRRQAILCG TCLIVSSVKE SQTGKMHVLP 60

LIGGKVEEVK KHQHCLAFSS SGPQSQTYYI CFDNFTEYLR WLRQASKVAS QRISSVDLSC 120

CSLEHLPANL FYSQDLTHLN LKQNFLKLNP SPSTSRALSE LQRFTKLKSL NLSNNNLGEF 180

PLAVCSIPTL TELNVSCNAL RSVPAVVGEM HNLQTFLLDG NFLQSLPDEL EHMHQLSYVS 240

LSFNEFTDIP GVLEKLTAMD KLCMSGNCMD TLNLQVLKRM PHIKHVDLRL NSIRRLEADE 300

IDFLHHVTQL DLRDNKLGEL DATVFNNVEV LHCERNQLVT LKTSGYFLKA LYASSNELVH 360

LDVHPVPNYL TYMDISRNHL ENLPEWVCDS RKLEVLDVGH NRISELPARL FYNSSLRKLL 420

AGHNLLGRLP DRLERTQVEV LDVQHNQLLE LPSNLLLKAD SLRFLNASAN KLEMLPPATL 480

SEETHSILQE LYLTNNNLTD KCVPLLTGHP HLKILHMAYN RLQSFPASKM AKLEELEEID 540

ISGNKLKAIP TTIMNCRRMH TVIAHSNCIE VFPEVMQLSE IKCVDLSCNE LSEITLPENL 600

PPKLQELDLT GNPRLALDHK TLELLNNIRC FKIDQPSAGD ASGAPAVWSH GYTEASGVKN 660

KLCVAALSAN NFCDNREALY GVFDGDRNVE VPYLLQCTMS DILAEELQKT KNEEEYMINT 720

FIVMQRKLGT AGQKLGGSAV LCHIKHDPMD PGGCFTLTSA NVGKCQTVLC RNGKPLPLSR 780

CYVMSCEEEL KRIKQHKAII TEDGKVNGVT DSTRILGYTF LHPSVVPRPH VQSITLTPQD 840

EFFILGSKGL WDSLSMDEAV EAVRNVPDAL AAAKKLCTLA QSYGCNDSIS AVVVQLNVTE 900

DSFCCCELNG VPPPSPGIFP QSVNVVIKDR PADALGMPSS SSGMASEISS EISTSEMSSE 960

VGSTASDEPP QVAMNESSPA YPGEQRCMLH PVCLSNSFQR QLSSATFSSA FSDNGLDSDD 1020

EEPIEGVFTN GSRVEVEVDI HCSRAKEKQL LQVPVEASDE GIVISANEDE PGLPKKAEYS 1080

ATGTIGRRRG NGSVAPQERS HNLIEVATDA PLRKTGGYFA APAQPDPDDQ FIIPPELEEE 1140

VKEIMKQHQE QQ 1152

Nucleotide Sequence
(FASTA)

AAGCCCCACA GCATTGGCAG CTCCGAGCGG ATTCAGCTCT CAGGAATGTA CAATGTTCGA 60

AAAGGGAAAA TACATTTGCC AGTCAACAGA TGGACAAGAC GTCAAGCTAT CCTTTGTGGA 120

ACATGCCTAA TTGTCTCATC AGTAAAAGAA AGCCAGACGG GAAAGATGCA TGTCCTGCCT 180

TTAATTGGTG GCAAAGTGGA AGAAGTGAAA AAGCACCAGC ACTGCTTAGC ATTTAGCTCT 240

TCTGGACCTC AAAGCCAGAC TTACTACATT TGTTTTGATA ACTTCACTGA ATATTTACGA 300

TGGCTTCGAC AAGCATCAAA GGTTGCATCA CAGCGCATAA GCTCAGTGGA TCTTTCATGC 360

TGCAGCTTGG AGCATCTGCC TGCCAACTTG TTTTATAGCC AAGACCTCAC TCATCTCAAT 420

TTAAAGCAGA ACTTCCTGAA GCTAAACCCT AGCCCATCCA CAAGCAGAGC ACTTAGTGAA 480

TTACAAAGAT TCACCAAGTT GAAGAGCCTT AACCTCTCCA ATAATAATTT AGGAGAATTC 540

CCACTGGCAG TTTGCAGTAT CCCAACCCTG ACAGAGCTCA ACGTGTCCTG CAATGCCCTC 600

AGAAGTGTTC CAGCAGTCGT AGGCGAGATG CACAACTTGC AGACATTTTT GCTGGATGGT 660

AACTTTCTCC AGTCCCTTCC TGATGAATTG GAGCATATGC ATCAGCTCAG CTATGTGAGT 720

CTGTCCTTCA ATGAATTCAC TGACATTCCA GGAGTATTAG AGAAGCTGAC TGCAATGGAC 780

AAACTCTGTA TGTCAGGAAA CTGTATGGAT ACACTCAACT TGCAAGTGTT AAAAAGGATG 840

CCTCATATTA AACATGTGGA CCTAAGATTG AATTCAATTA GGAGATTGGA GGCTGATGAA 900

ATAGACTTTC TCCACCACGT GACCCAGTTG GACCTCAGAG ACAACAAACT TGGAGAGCTG 960

GATGCAACAG TATTTAACAA TGTTGAAGTG TTACACTGTG AAAGAAATCA ACTGGTAACT 1020

CTGAAAACTA GTGGGTATTT TCTCAAAGCC CTGTATGCTT CCTCGAATGA ACTTGTTCAT 1080

CTTGATGTGC ATCCAGTTCC TAATTACCTG ACTTACATGG ATATTTCTAG AAATCATCTG 1140

GAAAACCTGC CTGAGTGGGT ATGTGACAGC AGAAAACTGG AAGTGTTGGA TGTTGGCCAC 1200

AATCGGATAA GTGAGCTGCC TGCCCGGTTG TTTTACAACA GCAGCTTGCG TAAACTGCTG 1260

GCAGGACATA ACTTGTTAGG AAGGCTACCA GATCGGCTTG AACGAACACA AGTGGAGGTC 1320

CTGGATGTGC AACACAACCA GCTCCTTGAA CTGCCATCTA ACCTACTTCT GAAAGCTGAC 1380

AGTCTGAGAT TTCTTAATGC CTCTGCCAAC AAACTGGAAA TGCTTCCCCC AGCAACCCTT 1440

TCTGAGGAGA CCCATAGCAT CTTACAGGAG TTGTATTTGA CCAATAACAA CCTCACGGAT 1500

AAATGTGTAC CCTTGTTAAC AGGCCATCCA CACCTGAAAA TTTTGCACAT GGCCTACAAC 1560

CGCCTACAGA GCTTCCCTGC AAGCAAAATG GCCAAGCTGG AAGAGTTGGA AGAAATTGAT 1620

ATTAGTGGTA ACAAGCTGAA AGCCATTCCA ACCACCATCA TGAACTGTAG ACGCATGCAT 1680

ACTGTAATTG CTCACTCCAA CTGCATTGAA GTCTTCCCAG AAGTCATGCA GCTTTCTGAA 1740

ATAAAGTGTG TGGATCTAAG CTGCAATGAA CTGAGTGAAA TCACATTGCC TGAAAACTTG 1800

CCTCCAAAAC TGCAAGAGCT GGACCTGACT GGAAACCCCA GATTGGCCTT GGATCACAAA 1860

ACCCTTGAGC TGCTGAACAA TATCCGTTGT TTCAAGATTG ACCAGCCCTC GGCTGGTGAT 1920

GCTTCAGGAG CTCCAGCTGT GTGGAGTCAC GGTTACACAG AGGCATCAGG AGTTAAGAAC 1980

AAGTTGTGTG TGGCAGCCCT GTCAGCCAAT AACTTCTGTG ACAACAGAGA GGCACTTTAT 2040

GGTGTTTTTG ATGGTGACCG CAATGTGGAA GTACCATATC TGTTGCAGTG CACCATGAGT 2100

GACATCTTGG CAGAAGAGCT ACAGAAAACA AAAAATGAAG AGGAATATAT GATCAACACT 2160

TTCATTGTTA TGCAAAGGAA ACTTGGAACA GCTGGACAAA AACTTGGAGG CTCTGCTGTC 2220

CTTTGCCATA TAAAACATGA TCCCATGGAC CCTGGAGGAT GCTTCACGTT AACCTCAGCA 2280

AATGTGGGGA AGTGCCAAAC TGTTCTCTGC CGGAATGGGA AGCCTCTGCC TTTGTCCAGG 2340

TGTTATGTGA TGAGTTGTGA AGAAGAGCTG AAGAGGATTA AGCAGCATAA GGCCATTATC 2400

ACAGAGGATG GCAAAGTAAA TGGTGTGACA GATTCAACGA GAATCTTGGG ATACACGTTC 2460

CTTCACCCAA GTGTTGTGCC ACGTCCTCAC GTCCAGTCCA TTACCTTAAC TCCACAAGAT 2520

GAGTTCTTCA TTCTGGGGAG CAAGGGGCTG TGGGACAGCC TCTCCATGGA TGAGGCAGTG 2580

GAAGCAGTCA GAAACGTGCC TGATGCGCTG GCAGCTGCCA AGAAGCTTTG CACTTTGGCC 2640

CAAAGTTACG GCTGCAACGA CAGTATCAGT GCGGTTGTGG TTCAGCTCAA TGTTACGGAG 2700

GACAGCTTCT GCTGCTGCGA ACTTAATGGG GTCCCACCCC CCAGCCCAGG CATTTTCCCC 2760

CAGTCTGTCA ATGTGGTCAT CAAGGACAGG CCAGCGGATG CTCTTGGGAT GCCATCTTCA 2820

AGCAGCGGCA TGGCTTCGGA GATCAGCAGC GAGATCTCCA CCTCGGAAAT GAGCAGCGAG 2880

GTGGGGTCCA CAGCCTCCGA TGAACCTCCG CAGGTAGCCA TGAACGAGAG CAGCCCGGCC 2940

TACCCCGGGG AGCAGCGCTG CATGCTGCAT CCTGTCTGCC TGTCCAACTC CTTCCAGCGG 3000

CAGCTCTCCA GCGCCACGTT CTCCAGCGCC TTCTCCGACA ATGGCCTCGA CAGCGATGAC 3060

GAGGAGCCAA TAGAGGGGGT GTTCACCAAC GGCAGCCGTG TGGAAGTGGA GGTGGACATC 3120

CATTGCAGCC GAGCGAAGGA GAAGCAGCTT CTCCAAGTGC CTGTGGAAGC CAGTGACGAA 3180

GGTATTGTCA TCAGTGCCAA CGAAGATGAG CCCGGCCTTC CCAAGAAAGC CGAATATTCT 3240

GCCACAGGCA CAATAGGGCG TCGGAGGGGC AATGGCTCTG TGGCACCCCA AGAGAGAAGC 3300

CATAACTTGA TTGAAGTTGC AACAGATGCA CCGCTTAGAA AAACAGGGGG ATATTTTGCT 3360

GCTCCGGCAC AGCCGGACCC GGATGACCAG TTCATCATCC CACCAGAGCT GGAAGAAGAG 3420

GTCAAGGAGA TCATGAAACA GCACCAGGAA CAACAA 3456

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g+++ +g +n+++ a+ s++nf++++e+     ++gv+DG+++ ev + +++++++il

Q: 649   SHGYTEASGVKNKLCVAALSANNFCDNREA-----LYGVFDGDRNVEVPYLLQCTMSDIL  703

         689***********************9885.....9************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

         aeel+    ++++ ++++ ++F+ ++++l       ++ +k G +av+++ik++

Q: 704   AEELQ----KTKNEEEYMINTFIVMQRKL------GTAGQKLGGSAVLCHIKHDpmdpgg  753

         ***99....999*****************......99***********************

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvLa  173

           +l+ anvG++++vLcrngk+++ls+ + +s+e+El+Ri+++++ ++++   +v+Gv+

Q: 754   cfTLTSANVGKCQTVLCRNGKPLPLSRCYVMSCEEELKRIKQHKAIITEDG--KVNGVTD  811

         ********************************************9999998..*******

S: 174   vsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekke  233

          +R lG ++l+p v+p+P+v+s++lt++def+iL+s+Glwd +s  eav++vr+v +

Q: 812   STRILGYTFLHPSVVPRPHVQSITLTPQDEFFILGSKGLWDSLSMDEAVEAVRNVPD---  868

         *********************************************************...

S: 234   aeqeaakkLvklalargskdnvsaivv  260

          + +aakkL++la+++g++d++sa+vv

Q: 869   -ALAAAKKLCTLAQSYGCNDSISAVVV  894

         .************************97

Domain Sequence
(FASTA)

SHGYTEASGV KNKLCVAALS ANNFCDNREA LYGVFDGDRN VEVPYLLQCT MSDILAEELQ 60

KTKNEEEYMI NTFIVMQRKL GTAGQKLGGS AVLCHIKHDP MDPGGCFTLT SANVGKCQTV 120

LCRNGKPLPL SRCYVMSCEE ELKRIKQHKA IITEDGKVNG VTDSTRILGY TFLHPSVVPR 180

PHVQSITLTP QDEFFILGSK GLWDSLSMDE AVEAVRNVPD ALAAAKKLCT LAQSYGCNDS 240

ISAVVV 246

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Loxodonta africana"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>