EKS-MEG-00068

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MEG-00068

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	449.3	7.3E-135	2276	2602	327

Status

Unreviewed

Ensembl Protein

ENSMGAP00000006286

UniProt Accession

G1N3I9;

Protein Name

Protein Synonyms/Alias

Gene Name

ATR

Gene Synonyms/Alias

ATR;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMGAG00000006227	ENSMGAP00000006286	ENSMGAT00000007033

Organism

Meleagris gallopavo

Functional Description

Protein Length

2627

Protein Sequence
(FASTA)

SASPEEYNTV VQKPRQILCQ FIDRILTDVD VVALELIKKS DSQPSSVMLL DFIQHIMKSS 60

PLMFVNVNAS QEETECNCIE FSNWIITRLL RIAVTPNCIL LHKNISDVIC SLLFLFKMRS 120

CSIFEILTKD LLQLFQDLIF LHERDTQKQL WGDVLVWPVI VKRFSSNSSD NVGYLRLAPL 180

HLMGMPNVEC LEVILLSILM DIAADVFFVR QDTVLWGIGC SLLEYGCPKV KALAMKFLIK 240

LIHLGGPPEQ LASVFFTVFF GILHSALEMD TEELELCGEP FLQLVKTLMP FDADSYKNIE 300

PVYLNMLLEK LCALFEGDIF MCLHSEKLKA AFCHILQYFL EFVPPGYESA VQVRKVHVNT 360

ICRVFVSVLG TQEEQEYLVS PLYTVLKAQT EEIFQELHQS QLDTSDTNGW SSSSDEVPEK 420

RLRLSLPAKH PKKSPAPVVL SPVNMKLKST LWNAITEKAT SLISVLEKES LTANILQAAE 480

GIAIILQLAA LCVVHCSPPT NSSSSVEPYS LDCVENIQFT WISSDFITRV VKVCGSLLET 540

ATKMVNLEQV IDRTVKIFDA LLYAQVKIPL SDQILDNICG LLSLPWICSH PDDDSFKTSA 600

FGTDLLVLSQ KTAQNFSPQT QSRCVFLLSL FPRNIHLDWR KSIYYWALQS PHEVIRATCV 660

KGFSFLLHPP SVQSFSMIPK ALLNQIQDES DLVKEACAAT VGKLSCCLSG TFSIQPPSAD 720

SAIKHVTSDI LCNSLIATCA HEKTCSVQAC VFKPFLILLE NKVSSLIKLA FIENVPHLCK 780

HLDFNNDESS VKVLIGSLLN LMEDPDKDVR VALSDCIKNI LESLDSEEGF IKELFVSRMK 840

EAYTHAKISR NNELKDTLIL TTGDIGRASK GDLVPFALLH LLHCLLSKSA SVAGAAYTEI 900

RSLAVAKSIK LQAFFSQYKK PICQFLVESL HSSQMTVLSA PCQGNELHKQ EAAHQREMAL 960

DMLSEVANVF DFPDLNRFLS RTLQVLLPDL AAKASPAASI LIRTIAKQLN VNRREILINN 1020

FKYIFSHLVC SCSKDELERA LHYLKNETEI ELGSLLRQDY QGLHNELLLR IGEHYQQVFN 1080

GLSILASFAS HDDPYQGPRE ITSPEQMADY LQPKLLGILA FFNMQLLSSS VGIEDKKMAL 1140

NSLMSLMKLM GPKHISSVRV KMMTTLRTAL RYKDDFPELC CRAWDCFVRS LDHSYLGSLL 1200

SHVIVALLPL IHIQPKETTA VFYFLIVENR DTVRDFLHEI YFLPDLPELK EIQVVLQEYR 1260

KESSKSTDLQ TTLQLSMRAI QHENVDVRIH ALTSLKETLY RNQEKLVKYV TDSETVEPVI 1320

SQLVTVLLIG CQDANSHARL LCGECLGELG AIDPGRLDFS TSETQGKDFT FVAGVEDLNF 1380

AYGLLMELTR AFLAYADNVR AQDSAAYAIQ ELLSIYDCRE TNSDCPGSRL WRRFPEHVQE 1440

ILEPHLNTRY KSYQKAIDWS KVKKPIYLSK LGDNFAEWSA TWAGYLITKV RHDLARKVFD 1500

CCSIMMKNDY KVTIYLLPHI LVYVLLGCSQ EDQQEVYMEI MAVLKHDDQC SRRLQDSASD 1560

LSQLSTQTVF SMLDHLTQWA RHKFQMLIAE KNTSKSSKDR NDLKTSSEDY GEYQNVTRFL 1620

DLIPQDTLAV ASFRSKAYTR AVMHFESFIT EKKQNIQEHL GFLQKLYAAM HEPDGVAGVS 1680

AIRKAEPSLK EQILEHESIG LLRDATACYD RAIQLEPDQI IHYHGVVKSM LGLGQLSTVI 1740

TQVNGVLANR SEWVSELNTY RVEAAWKLSQ WDLLENYLAS DVKSTAWSVR LGHLLLSAKK 1800

KNEVAFYETL KVVRAEQIVP LSAASFERGS YQRGYEHIIR LHMLCELEHS IGPMFQQPDG 1860

EHSRDSLNWC ARIEMTQNSY RAKEPILALR RALLSLSKSQ DYSELVGQCW LQSARVARKA 1920

GHHQTAYNAL LNAGESTLSE LYIERAKWLW SKGEVHQALI VLQKGVELCF PENKAPCNTK 1980

NQLVHGRAML LVGRFMEETA NFESNAVMKK YKDVTLLLPE WEDGHFYLAK YYDKLMPMVT 2040

DNKMEKQGDL IRYIVHHFGR SLQYGNQFIY QSMPRMLSLW LDFGAKAYEC DKASRSERIQ 2100

MKNDLAKINK VITEHTNQLA PYQFLTAFSQ LISRICHSHD EVFAVLMVIV AKVFLAYPQQ 2160

AMWMMTAVSK SSYPMRVNRC KEILNKAINM KESLGKFIGD ATRLTDKLLE LCNKPVDGNS 2220

SALSMNIHFR TLKRLVEEHT FSQILIPLQS VMIPTLPSIP GTHANHDPFP GCWAYIAGFD 2280

DTVEILASLQ KPKKITLKGS DGKSYIMMCK PKDDLRKDCR LMEFNSLINK CLRKDAESRR 2340

RELHIRTYAV IPLNDECGII EWVNNTAGLR NILIKLYKEK GIYMTGKELR QHMLPKSAPL 2400

SEKLKMFKEV LLPRHPPVFH EWFLRTFPDP TSWYNSRSAY CRSVAVMSMV GYILGLGDRH 2460

GENILFDSLT GECVHVDFNC LFNKGETFEV PEIVPFRLTH NMVNGMGPMG TEGLFRRACE 2520

VTMRLMRDQR EPLMSVLKTF LHDPLVEWSK PVKGNMKAQV NETGEVVNEK AKTHVLDIEQ 2580

RLQGVIKTRN RIKGLPLSIE GHVHYLIQEA SDDNLLCQMY MGWAPYM 2627

Nucleotide Sequence
(FASTA)

AGTGCTAGTC CAGAAGAATA CAATACAGTT GTTCAGAAAC CAAGACAAAT ACTCTGCCAA 60

TTCATTGACA GAATTCTTAC AGATGTAGAT GTGGTTGCTC TGGAACTCAT TAAGAAATCA 120

GATTCACAGC CAAGTTCTGT AATGCTACTA GATTTCATTC AACATATCAT GAAATCTTCT 180

CCCCTTATGT TTGTAAATGT CAATGCAAGT CAAGAGGAAA CAGAATGCAA TTGCATTGAA 240

TTTAGTAATT GGATCATAAC AAGACTTCTC CGAATTGCTG TGACTCCAAA CTGTATCCTG 300

TTGCACAAGA ACATCTCCGA TGTCATTTGC TCTTTACTTT TTCTGTTTAA AATGAGAAGT 360

TGTTCCATCT TTGAAATACT AACAAAAGAC TTGCTACAGC TTTTCCAAGA TTTAATCTTC 420

CTGCATGAAA GAGACACACA AAAGCAGCTC TGGGGAGATG TGCTGGTATG GCCGGTGATT 480

GTAAAGAGAT TTTCAAGCAA TTCAAGTGAC AATGTGGGAT ATTTAAGATT AGCACCATTA 540

CACCTGATGG GTATGCCCAA TGTAGAATGT CTGGAAGTTA TATTGTTGTC TATCCTGATG 600

GATATTGCTG CAGATGTTTT TTTTGTAAGA CAAGATACTG TTCTCTGGGG AATAGGGTGC 660

TCCCTGTTAG AGTATGGTTG TCCAAAAGTT AAAGCTTTGG CAATGAAGTT TTTAATAAAA 720

TTAATTCATT TGGGAGGACC TCCAGAACAG CTGGCCAGTG TTTTCTTCAC AGTCTTTTTT 780

GGAATTCTAC ATTCAGCACT TGAAATGGAT ACTGAAGAAC TGGAACTCTG TGGAGAACCA 840

TTTTTACAAT TGGTTAAAAC GTTGATGCCT TTTGACGCAG ATTCTTACAA AAATATTGAA 900

CCTGTCTATT TGAATATGCT ACTAGAGAAG CTTTGTGCAC TGTTTGAAGG AGATATTTTT 960

ATGTGTCTTC ATTCTGAAAA ACTGAAAGCT GCTTTTTGCC ATATACTGCA ATATTTTCTG 1020

GAGTTTGTTC CACCTGGCTA TGAATCTGCT GTACAAGTAA GAAAAGTCCA TGTCAATACC 1080

ATATGCAGAG TTTTTGTGAG TGTGCTTGGA ACTCAGGAAG AACAAGAGTA TCTGGTGAGT 1140

CCACTTTATA CAGTATTAAA AGCACAAACA GAAGAAATCT TTCAGGAGCT TCATCAGAGC 1200

CAGCTAGATA CTTCTGACAC TAATGGGTGG AGCAGCAGCA GTGATGAAGT TCCAGAGAAA 1260

AGACTGCGAC TAAGCCTACC AGCAAAGCAT CCAAAGAAAT CGCCTGCACC AGTAGTACTT 1320

AGCCCTGTAA ACATGAAATT GAAGAGCACA CTTTGGAATG CCATCACAGA GAAAGCCACA 1380

TCCTTAATAT CTGTCCTCGA GAAAGAAAGT CTGACAGCGA ATATTCTTCA GGCTGCAGAA 1440

GGAATTGCCA TAATTCTGCA GCTAGCTGCG CTGTGTGTAG TTCATTGTTC TCCCCCAACA 1500

AATTCTAGCA GCAGTGTGGA ACCATACTCA TTGGATTGTG TAGAGAATAT ACAATTCACG 1560

TGGATTTCCT CTGACTTTAT CACAAGAGTA GTAAAAGTGT GTGGGAGCCT GTTAGAGACT 1620

GCTACAAAGA TGGTTAACCT AGAACAAGTG ATTGACAGAA CAGTGAAAAT CTTTGATGCT 1680

TTGCTGTATG CACAAGTAAA AATTCCACTG AGTGATCAGA TTCTTGATAA TATATGTGGA 1740

CTGCTGTCTC TACCTTGGAT TTGCAGCCAT CCTGATGATG ATTCTTTTAA AACATCTGCT 1800

TTTGGGACTG ATCTTCTAGT TTTGAGTCAA AAAACTGCAC AAAATTTCTC ACCTCAAACT 1860

CAGTCACGTT GTGTGTTCCT TCTATCTCTC TTCCCAAGAA ACATTCATCT GGATTGGCGA 1920

AAATCCATTT ATTACTGGGC ACTACAAAGT CCCCATGAAG TAATTCGGGC TACTTGTGTG 1980

AAAGGATTCT CTTTCCTGCT TCATCCACCA AGCGTGCAGT CTTTCAGTAT GATTCCGAAG 2040

GCTCTTTTAA ATCAAATCCA AGATGAGTCT GATCTAGTCA AGGAGGCTTG TGCTGCTACT 2100

GTTGGGAAAT TATCTTGCTG TCTTTCTGGT ACATTCAGTA TACAGCCTCC TTCAGCAGAC 2160

TCTGCTATAA AGCATGTTAC CTCTGATATT TTATGTAACA GCCTCATTGC GACTTGTGCT 2220

CATGAAAAAA CTTGCTCTGT GCAAGCCTGT GTTTTTAAGC CATTTCTTAT TCTTCTTGAG 2280

AACAAAGTAT CCAGTTTGAT AAAACTAGCA TTTATAGAAA ACGTTCCTCA CCTTTGCAAA 2340

CATCTGGATT TTAACAATGA TGAGTCAAGT GTGAAGGTTC TCATTGGGTC TTTATTAAAT 2400

CTAATGGAAG ATCCAGACAA AGATGTACGA GTTGCTCTCA GTGACTGCAT AAAGAACATA 2460

TTAGAATCCT TAGACTCTGA AGAAGGATTC ATAAAAGAGC TCTTTGTTTC AAGAATGAAA 2520

GAAGCCTATA CACATGCCAA AATATCAAGA AATAATGAGC TTAAAGATAC CTTGATTCTC 2580

ACAACAGGAG ATATTGGAAG GGCATCAAAA GGAGATTTGG TACCATTTGC CCTCTTGCAT 2640

TTGTTGCATT GTTTGTTGTC CAAGTCAGCT TCTGTGGCTG GAGCAGCTTA CACAGAAATT 2700

CGGTCCCTGG CAGTAGCTAA GTCCATAAAA CTACAAGCTT TTTTCAGTCA GTACAAGAAA 2760

CCTATCTGTC AGTTTCTAGT GGAATCCCTG CACTCCAGCC AGATGACAGT ATTGAGTGCT 2820

CCATGCCAGG GTAATGAGCT GCACAAACAA GAAGCTGCTC ACCAGAGAGA AATGGCTCTG 2880

GACATGTTGT CTGAAGTTGC TAATGTATTT GACTTTCCAG ATCTAAATCG CTTTTTGTCA 2940

CGGACTCTGC AAGTTTTGCT GCCTGACCTT GCAGCCAAGG CCAGTCCTGC AGCCTCCATC 3000

CTTATTCGAA CCATAGCAAA ACAACTGAAC GTAAACCGAA GAGAGATTTT AATCAACAAC 3060

TTCAAATACA TCTTCTCTCA TTTGGTCTGT TCCTGCTCTA AGGATGAACT TGAGCGGGCA 3120

CTTCATTACC TCAAGAATGA GACTGAGATC GAACTGGGCA GCTTGTTGAG ACAGGACTAC 3180

CAGGGACTGC ATAATGAATT ATTGCTACGT ATAGGAGAGC ACTATCAGCA AGTATTCAAT 3240

GGTTTGTCAA TATTGGCTTC ATTTGCATCT CATGATGATC CCTATCAGGG ACCTAGGGAA 3300

ATAACGTCAC CTGAGCAAAT GGCTGATTAT CTGCAGCCTA AATTGCTTGG TATCTTGGCC 3360

TTTTTTAACA TGCAGTTATT GAGTTCTAGT GTGGGCATTG AGGATAAAAA AATGGCCTTA 3420

AACAGTCTTA TGTCTTTAAT GAAGCTTATG GGTCCCAAAC ACATCAGTTC AGTACGAGTG 3480

AAGATGATGA CTACTCTGAG AACAGCTCTA AGATACAAGG ACGACTTTCC AGAACTGTGT 3540

TGCAGGGCCT GGGACTGTTT TGTTCGAAGT CTGGATCATT CATACCTTGG CTCCTTGCTT 3600

AGTCATGTGA TAGTAGCTTT GCTGCCTCTA ATACATATCC AGCCAAAGGA AACTACAGCA 3660

GTATTTTACT TTCTCATAGT TGAGAACAGG GATACAGTAC GGGACTTCTT ACATGAGATA 3720

TATTTTCTGC CTGACCTTCC GGAACTAAAG GAAATTCAAG TAGTCCTTCA GGAATATCGA 3780

AAGGAATCCT CCAAAAGCAC TGACTTGCAG ACGACGCTGC AGCTGTCCAT GAGAGCTATT 3840

CAGCATGAGA ATGTGGATGT TCGTATCCAT GCACTTACCA GCCTGAAAGA AACGTTATAT 3900

AGAAATCAGG AAAAATTGGT GAAGTATGTA ACAGACAGTG AAACCGTAGA GCCAGTCATC 3960

TCTCAGTTGG TAACTGTACT TCTGATTGGC TGTCAGGATG CAAATTCTCA TGCCCGGCTA 4020

CTTTGTGGGG AATGTTTAGG TGAACTGGGA GCCATAGACC CTGGCAGGCT GGATTTTTCA 4080

ACGAGTGAAA CTCAAGGAAA AGATTTTACA TTTGTGGCTG GTGTGGAGGA TCTGAATTTT 4140

GCCTATGGAT TACTGATGGA ACTGACTAGA GCATTTCTTG CTTATGCTGA TAATGTTCGT 4200

GCTCAGGATT CTGCTGCATA TGCCATTCAG GAGTTACTGT CTATTTATGA CTGTAGAGAG 4260

ACAAACAGTG ACTGCCCAGG CTCCAGGCTT TGGAGGAGAT TTCCTGAGCA TGTGCAGGAA 4320

ATCTTGGAAC CTCACTTAAA TACACGGTAC AAGAGTTATC AAAAGGCTAT AGATTGGTCA 4380

AAGGTGAAGA AGCCTATTTA CCTAAGCAAA TTAGGTGACA ATTTTGCAGA ATGGTCAGCA 4440

ACTTGGGCAG GTTACCTTAT AACAAAGGTA CGACATGATC TCGCCAGAAA AGTTTTTGAT 4500

TGCTGCAGTA TTATGATGAA GAATGACTAT AAAGTGACAA TTTATCTGCT ACCACACATC 4560

CTTGTTTATG TTTTGTTGGG ATGCAGTCAG GAGGACCAAC AAGAGGTTTA CATGGAGATT 4620

ATGGCTGTTC TGAAACATGA TGATCAGTGT AGCAGGAGAC TTCAAGACAG TGCATCTGAT 4680

CTAAGCCAGC TGAGCACGCA GACAGTGTTC TCCATGCTTG ATCATCTAAC TCAGTGGGCT 4740

AGACACAAGT TTCAGATGCT TATTGCTGAA AAAAATACTA GCAAGTCTAG CAAAGACAGA 4800

AATGACCTAA AAACTTCAAG CGAGGACTAT GGAGAGTATC AGAACGTGAC ACGCTTTTTA 4860

GACCTGATAC CTCAAGATAC ACTGGCTGTG GCTTCTTTTC GCTCGAAGGC TTACACAAGG 4920

GCTGTGATGC ATTTTGAGTC ATTCATCACA GAGAAAAAGC AAAACATTCA GGAGCATCTT 4980

GGATTTCTGC AGAAATTGTA TGCTGCAATG CATGAGCCAG ATGGAGTGGC TGGAGTGAGT 5040

GCAATTCGGA AAGCAGAACC ATCTCTCAAA GAGCAAATCC TCGAACATGA AAGTATTGGC 5100

TTGTTAAGAG ATGCCACAGC CTGTTATGAT AGGGCTATCC AACTAGAACC TGATCAGATT 5160

ATTCATTACC ATGGTGTAGT GAAGTCCATG TTAGGCCTTG GTCAATTATC TACTGTAATT 5220

ACTCAAGTGA ATGGAGTACT TGCAAACAGG TCTGAATGGG TTTCTGAATT GAACACATAC 5280

AGAGTTGAAG CAGCCTGGAA ACTGTCACAG TGGGATTTAC TGGAGAATTA TTTGGCTTCA 5340

GATGTGAAGT CCACTGCTTG GAGTGTCAGA TTAGGACATT TATTACTATC GGCCAAGAAG 5400

AAAAATGAAG TCGCATTTTA TGAAACGCTC AAGGTTGTTC GAGCAGAACA GATTGTGCCC 5460

CTTTCAGCAG CGAGCTTTGA AAGAGGATCC TATCAGCGAG GATATGAGCA CATTATCAGG 5520

TTGCATATGC TCTGTGAGTT GGAACATAGT ATTGGACCAA TGTTTCAGCA ACCAGATGGT 5580

GAACACAGTA GAGATTCCCT GAATTGGTGT GCTCGTATTG AAATGACCCA GAACTCTTAC 5640

AGAGCGAAAG AACCTATTCT AGCACTAAGA AGGGCTTTGC TTAGTCTTAG TAAAAGCCAG 5700

GATTACAGTG AGCTTGTTGG TCAGTGTTGG CTCCAGAGTG CTAGAGTTGC AAGAAAAGCT 5760

GGTCATCATC AGACTGCATA TAATGCTCTT CTGAATGCTG GGGAATCTAC ACTCTCAGAA 5820

CTTTATATAG AAAGAGCAAA GTGGCTCTGG TCCAAGGGTG AGGTTCACCA AGCACTTATT 5880

GTTCTCCAGA AAGGAGTGGA GCTATGTTTC CCTGAGAATA AAGCGCCATG TAATACCAAA 5940

AATCAGCTCG TCCATGGTCG GGCAATGCTG CTAGTTGGTA GATTTATGGA AGAAACTGCT 6000

AACTTTGAAA GCAATGCAGT TATGAAAAAG TATAAGGATG TTACACTTTT GTTGCCAGAA 6060

TGGGAAGATG GACATTTTTA TCTTGCTAAA TACTATGATA AATTAATGCC AATGGTAACT 6120

GACAATAAGA TGGAAAAACA AGGAGATCTG ATTAGATACA TAGTTCATCA TTTTGGGAGG 6180

TCTCTACAGT ATGGAAACCA ATTTATCTAT CAGTCAATGC CAAGAATGCT ATCTTTATGG 6240

TTGGACTTTG GAGCAAAAGC ATATGAGTGT GATAAAGCAA GTCGTTCGGA ACGCATTCAA 6300

ATGAAAAATG ATTTGGCTAA AATAAATAAA GTGATTACAG AGCACACAAA TCAGCTAGCA 6360

CCTTATCAGT TTCTGACAGC TTTTTCTCAG TTAATCTCCC GAATCTGCCA TTCTCATGAT 6420

GAAGTCTTTG CTGTTCTGAT GGTGATTGTT GCTAAGGTGT TTCTGGCCTA CCCACAGCAA 6480

GCAATGTGGA TGATGACTGC TGTGTCTAAG TCTTCGTACC CTATGCGTGT CAATAGATGC 6540

AAGGAAATAC TAAATAAAGC TATCAACATG AAGGAGTCCT TAGGAAAATT TATTGGAGAT 6600

GCAACACGCC TTACGGATAA ACTCTTAGAA CTGTGCAACA AACCGGTTGA TGGAAACAGC 6660

TCAGCATTAA GCATGAATAT TCATTTCAGA ACACTTAAGA GATTGGTAGA AGAGCACACA 6720

TTCAGTCAAA TTCTCATTCC ATTACAATCT GTAATGATAC CAACTCTTCC TTCAATTCCT 6780

GGTACACATG CTAACCATGA CCCTTTTCCT GGATGCTGGG CCTACATTGC AGGCTTTGAT 6840

GATACGGTAG AAATTCTTGC TTCCCTTCAA AAGCCAAAGA AGATCACTTT AAAAGGTTCG 6900

GATGGGAAAT CTTATATTAT GATGTGTAAA CCTAAAGATG ATCTAAGAAA GGACTGTCGG 6960

CTCATGGAAT TCAACTCTCT TATTAACAAG TGCTTAAGAA AAGATGCAGA GTCACGTCGG 7020

CGAGAACTCC ATATACGAAC CTATGCAGTT ATTCCATTAA ATGATGAATG TGGCATAATT 7080

GAATGGGTGA ACAATACTGC TGGTTTAAGA AATATCCTAA TAAAACTTTA TAAGGAGAAG 7140

GGTATCTATA TGACTGGAAA GGAACTACGT CAGCATATGC TTCCAAAGTC AGCACCTTTG 7200

TCTGAAAAGC TGAAAATGTT CAAAGAAGTC CTTCTGCCTC GTCATCCTCC TGTTTTTCAT 7260

GAATGGTTTC TTAGAACATT TCCTGATCCT ACTTCATGGT ATAACAGCAG GTCTGCCTAC 7320

TGCCGTTCTG TTGCAGTCAT GTCAATGGTA GGTTACATAC TTGGTCTAGG AGACCGTCAT 7380

GGTGAAAACA TCCTGTTTGA TTCTTTGACT GGTGAATGTG TGCATGTAGA TTTCAACTGC 7440

CTTTTCAATA AGGGAGAAAC TTTTGAAGTT CCGGAAATCG TGCCTTTTCG TCTCACACAT 7500

AACATGGTTA ATGGAATGGG TCCAATGGGA ACAGAAGGTC TCTTCCGAAG AGCTTGTGAA 7560

GTCACAATGA GGCTTATGCG TGATCAAAGG GAGCCTTTAA TGAGTGTCTT AAAGACTTTT 7620

CTTCATGATC CTCTTGTGGA GTGGAGTAAG CCTGTTAAAG GGAATATGAA AGCACAGGTG 7680

AACGAAACTG GAGAAGTTGT CAATGAAAAG GCCAAAACCC ATGTCCTTGA TATAGAACAA 7740

AGGCTACAAG GTGTTATTAA GACTAGAAAC AGAATAAAAG GATTACCCTT ATCTATTGAA 7800

GGGCATGTTC ATTACCTCAT TCAAGAAGCA AGCGATGACA ATCTGCTCTG CCAAATGTAT 7860

ATGGGCTGGG CTCCATATAT GTAA 7884

Domain Profile

S: 1     iagfderveilaskqkpkklllrGsdgkeypyLvkgkeDlrqdervlqlfslvNtlLakd  60

         iagfd++veilas+qkpkk++l+Gsdgk+y++++k+k+Dlr+d+r+++++sl+N++L+kd

Q: 2276  IAGFDDTVEILASLQKPKKITLKGSDGKSYIMMCKPKDDLRKDCRLMEFNSLINKCLRKD  2335

         89**********************************************************

S: 61    ketsrrkLkirtykVvplstrsgliewventvsLkellkklvekkavlldqpisyrykdl  120

         +e++rr+L+irty+V+pl++++g+iewv+nt++L+++l kl+++k++++          +

Q: 2336  AESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRNILIKLYKEKGIYMT--------GK  2387

         *************************************************5........99

S: 121   stvqarkpklkhlklslevfkevlenlvpkdllkklllekfpspeewfelrkaytrslAv  180

         + +q + pk++ l+++l++fkevl +++p+ ++++++l++fp+p++w+++r+ay+rs+Av

Q: 2388  ELRQHMLPKSAPLSEKLKMFKEVLLPRHPP-VFHEWFLRTFPDPTSWYNSRSAYCRSVAV  2446

         *****************************8.*****************************

S: 181   islvgyiLgLgdrhlenllidqetgevvhidfgvafekaktqlkvpekvPFRLTrnivna  240

         +s+vgyiLgLgdrh en+l+d+ tge+vh+df++ f+k++t ++vpe+vPFRLT+n+vn+

Q: 2447  MSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGET-FEVPEIVPFRLTHNMVNG  2505

         *****************************************.******************

S: 241   lgvtgveGvfrasceavlrvlreskeklltiLevflydplvdwkk.....kkktsketee  295

         +g++g+eG+fr++ce ++r++r+++e l+++L++fl+dplv+w+k     +k++ +et+e

Q: 2506  MGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEWSKpvkgnMKAQVNETGE  2565

         ************************************************************

S: 296   elaekakaealkikkllskvekaenavatrdllllee  332

         +++ekak++ l+i+++l++v k++n+++ ++l+++++

Q: 2566  VVNEKAKTHVLDIEQRLQGVIKTRNRIKGLPLSIEGH  2602

         ********************************99987

Domain Sequence
(FASTA)

IAGFDDTVEI LASLQKPKKI TLKGSDGKSY IMMCKPKDDL RKDCRLMEFN SLINKCLRKD 60

AESRRRELHI RTYAVIPLND ECGIIEWVNN TAGLRNILIK LYKEKGIYMT GKELRQHMLP 120

KSAPLSEKLK MFKEVLLPRH PPVFHEWFLR TFPDPTSWYN SRSAYCRSVA VMSMVGYILG 180

LGDRHGENIL FDSLTGECVH VDFNCLFNKG ETFEVPEIVP FRLTHNMVNG MGPMGTEGLF 240

RRACEVTMRL MRDQREPLMS VLKTFLHDPL VEWSKPVKGN MKAQVNETGE VVNEKAKTHV 300

LDIEQRLQGV IKTRNRIKGL PLSIEGH 327

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0001741	; C:XY body
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0071480	; P:cellular response to gamma radiation
GO:0034644	; P:cellular response to UV
GO:0000077	; P:DNA damage checkpoint
GO:0006281	; P:DNA repair
GO:0008156	; P:negative regulation of DNA replication
GO:0018105	; P:peptidyl-serine phosphorylation
GO:0043517	; P:positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0046777	; P:protein autophosphorylation
GO:0043393	; P:regulation of protein binding
GO:0090399	; P:replicative senescence

KEGG

InterPros

IPR011989	; ARM-like.
IPR016024	; ARM-type_fold.
IPR003152	; FATC.
IPR021133	; HEAT_type_2.
IPR011009	; Kinase-like_dom.
IPR000403	; PI3/4_kinase_cat_dom.
IPR018936	; PI3/4_kinase_CS.
IPR003151	; PIK-rel_kinase_FAT.
IPR014009	; PIK_FAT.
IPR011990	; TPR-like_helical.
IPR012993	; UME.

Pfam

PF02259	; FAT; 1.
PF02260	; FATC; 1.
PF00454	; PI3_PI4_kinase; 1.
PF08064	; UME; 1.

SMARTs

SM00146	; PI3Kc; 1.
SM00802	; UME; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS50077	; HEAT_REPEAT; 1.
PS00916	; PI3_4_KINASE_2; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013