EPS-MEG-00033

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-MEG-00033

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	191.0	2.6E-56	2	216	215

Status

Unreviewed

Ensembl Protein

ENSMGAP00000007818

UniProt Accession

G1N6S1;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1D

Gene Synonyms/Alias

PPM1D;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMGAG00000007680	ENSMGAP00000007818	ENSMGAT00000008601

Organism

Meleagris gallopavo

Functional Description

Protein Length

447

Protein Sequence
(FASTA)

AEWPKTMTGL PSTSGTTASV VIIRGSKMFV AHVGDSGVVL GVQDDPKDDF VRAVEVTQDH 60

KPELPKERER IEGLGGSVIN KSGVNRVVWK RPRLTHNGPV RRSTVIDQIP FLAVARALGD 120

LWSYDFYTGE FVVSPEPDTS VHTIDPQKHK YIILGSDGLW NMIPPQDAIS MCQDHEEKKY 180

FMGEHRQSCA KMLVNRALGR WRQRMLRADN TSAIVICISP LQDSKNNLEN EEELYLNLAE 240

SPCYSSPDTN VMTPSHCCTP PVKLLEDDPW PRLNASEPVP SLMHSSMISE KYAELPNEIA 300

KSNLPSSGAA LKDSGPQDEK CSKALALRIQ ESYSNGLSVS LSPSNSTNSG TDQKGLKVSP 360

NSQTKAQDAE RTPTANFKRT LEESNSGPAV KKPRRGLSRN MGVQAEGIST TLQRKNSNKL 420

AMRRSLRGQK KLGSSLFHPP RKAVCVC 447

Nucleotide Sequence
(FASTA)

GCAGAGTGGC CAAAGACCAT GACCGGTCTC CCGAGCACAT CGGGAACCAC CGCCAGCGTG 60

GTCATCATCC GAGGCTCCAA GATGTTTGTC GCTCACGTGG GCGACTCCGG GGTGGTGCTG 120

GGAGTCCAGG ATGACCCCAA AGATGACTTT GTGAGAGCTG TGGAGGTGAC GCAGGACCAC 180

AAGCCTGAGC TTCCCAAAGA AAGGGAGAGG ATTGAAGGCC TTGGGGGCAG TGTCATCAAC 240

AAGTCTGGTG TGAATCGTGT TGTCTGGAAG AGACCTCGCC TGACTCACAA CGGCCCTGTG 300

CGCCGCAGCA CCGTCATCGA CCAGATTCCC TTCCTGGCCG TGGCCAGAGC TCTGGGTGAT 360

CTGTGGAGCT ACGACTTCTA CACTGGTGAA TTTGTTGTGT CTCCTGAACC TGACACTAGT 420

GTGCACACCA TCGATCCCCA GAAGCACAAG TACATTATCC TTGGCAGTGA CGGACTGTGG 480

AACATGATCC CACCTCAAGA TGCTATCTCC ATGTGCCAGG ATCACGAGGA GAAAAAGTAC 540

TTCATGGGTG AGCACCGCCA GTCCTGTGCC AAAATGCTGG TGAACAGAGC ACTGGGCCGG 600

TGGAGGCAGC GCATGCTTCG TGCAGATAAC ACCAGTGCCA TCGTGATCTG CATCTCACCA 660

CTGCAGGATA GCAAAAACAA CTTGGAAAAT GAAGAAGAAC TGTATCTCAA CTTGGCAGAG 720

AGTCCCTGCT ATAGCAGCCC TGATACAAAT GTCATGACGC CCTCCCACTG CTGCACCCCA 780

CCTGTCAAGC TTTTAGAGGA TGATCCGTGG CCACGACTGA ATGCTTCTGA GCCTGTTCCC 840

TCCCTCATGC ATAGCAGCAT GATCTCAGAA AAATACGCCG AGCTGCCAAA CGAGATTGCC 900

AAAAGCAATT TACCTTCATC AGGAGCAGCC CTAAAGGATT CAGGTCCACA GGACGAGAAG 960

TGCAGCAAAG CGTTGGCTTT GAGGATACAG GAATCCTACA GTAATGGTTT GTCAGTCAGT 1020

CTATCCCCAT CCAACTCTAC AAATTCAGGC ACGGACCAAA AAGGCTTAAA GGTGTCTCCT 1080

AACAGCCAAA CAAAAGCCCA GGATGCGGAG AGGACACCCA CAGCAAACTT TAAAAGGACA 1140

TTAGAAGAAT CCAATTCTGG CCCTGCTGTG AAGAAGCCGA GGCGCGGCCT GAGCCGAAAC 1200

ATGGGTGTCC AAGCAGAGGG CATATCCACA ACGCTGCAGC GCAAGAACTC AAACAAGCTG 1260

GCCATGCGGC GCAGCCTGCG CGGCCAGAAG AAGCTCGGCA GTTCACTCTT CCACCCACCC 1320

AGGAAAGCAG TCTGCGTTTG CTGA 1344

Domain Profile

S: 91    kvleeksldidksGstavvalikdsklyvanvGdSravLcrngk.......avelssdHk  143

         +++++++  +++sG+ta+v++i++sk++va+vGdS++vL+ +++       ave+++dHk

Q: 2     EWPKTMTGLPSTSGTTASVVIIRGSKMFVAHVGDSGVVLGVQDDpkddfvrAVEVTQDHK  61

         588999***********************************77656999999********

S: 144   psredEleRieeaggsvilkdga.Rv.....................lGvLavsRalGdl  181

         p+ ++E+eRie  ggsvi+k+g+ Rv                     +++Lav+RalGdl

Q: 62    PELPKERERIEGLGGSVINKSGVnRVvwkrprlthngpvrrstvidqIPFLAVARALGDL  121

         ************************************************************

S: 182   ylk......pyvtpePevtshrltsede.fliLasDGlwdvvsneeavslvrdvle....  230

         +++      ++v+peP++++h+++++++ ++iL+sDGlw+++++++a+s+++d++e

Q: 122   WSYdfytgeFVVSPEPDTSVHTIDPQKHkYIILGSDGLWNMIPPQDAISMCQDHEEkkyf  181

         ************************************************************

S: 231   kkeaeqeaakkLvklalargsk.....dnvsaivv  260

         ++e+ q++ak+Lv++al r+++     dn+saiv+

Q: 182   MGEHRQSCAKMLVNRALGRWRQrmlraDNTSAIVI  216

         *********************************97

Domain Sequence
(FASTA)

EWPKTMTGLP STSGTTASVV IIRGSKMFVA HVGDSGVVLG VQDDPKDDFV RAVEVTQDHK 60

PELPKERERI EGLGGSVINK SGVNRVVWKR PRLTHNGPVR RSTVIDQIPF LAVARALGDL 120

WSYDFYTGEF VVSPEPDTSV HTIDPQKHKY IILGSDGLWN MIPPQDAISM CQDHEEKKYF 180

MGEHRQSCAK MLVNRALGRW RQRMLRADNT SAIVI 215

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0000086	; P:G2/M transition of mitotic cell cycle
GO:0035970	; P:peptidyl-threonine dephosphorylation

KEGG

InterPros

IPR001932	; PP2C-like.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481

; PP2C; 1.

SMARTs

SM00332

; PP2Cc; 1.

Prosites

Prints

Created Date

20-Feb-2013