EPS-MEG-00030

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-MEG-00030

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	227.1	2.5E-67	94	344	251

Status

Unreviewed

Ensembl Protein

ENSMGAP00000008577

UniProt Accession

G1N8E7;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1K

Gene Synonyms/Alias

PPM1K;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMGAG00000008373	ENSMGAP00000008577	ENSMGAT00000009376

Organism

Meleagris gallopavo

Functional Description

Protein Length

372

Protein Sequence
(FASTA)

MSTAALIHLV RNGGYQVRRR ALLTSRLLQD EKRSTAECYI STSERRASRF DPDGSGRPAT 60

WDTFGIWDNR IDEPILLPPS IKYGKPIPKV SLSKVGCASH IGKRKENEDR FDYAQLTEDV 120

LYFAVYDGHG GAAAADFCAK NMERYIKEFA VQEENLEKVL NDAFLEINKA YERHAQLSAD 180

ATLMNSGTTA TVALLRDGIE LVVASVGDSR ALLCRKGKAM KLTIDHTPER KEEKERIRKC 240

GGFVAWNSLG QPHVNGRLAM TRSIGDLDLK NSGVIAQPET KRVQLHHADD GFLVLTTDGI 300

NFMVNSQEIC DFINQCHDPA EAAHVVTEQA MQYGTEDNST VVIVPFGAWG KYKNGEINFS 360

FSRSFASSGR WA 372

Nucleotide Sequence
(FASTA)

ATGTCAACAG CTGCTTTAAT CCATTTGGTA AGAAACGGAG GTTATCAAGT ACGAAGGAGA 60

GCCCTGCTGA CATCCCGCCT CTTGCAAGAC GAGAAGCGTT CGACAGCCGA GTGCTACATT 120

TCCACCTCCG AACGCCGGGC ATCCCGCTTC GATCCGGACG GGAGCGGGCG GCCCGCCACG 180

TGGGACACCT TTGGCATCTG GGACAATCGC ATTGATGAAC CTATTCTCCT CCCACCTAGC 240

ATAAAGTATG GAAAGCCGAT TCCAAAAGTC AGCCTGAGCA AAGTGGGCTG TGCCAGTCAT 300

ATTGGGAAGC GGAAGGAAAA TGAAGACCGC TTCGATTATG CTCAGCTGAC TGAGGATGTC 360

CTGTACTTTG CTGTATATGA TGGACATGGC GGAGCGGCAG CAGCAGACTT CTGCGCTAAG 420

AACATGGAAA GATATATCAA GGAATTTGCT GTTCAGGAAG AGAACTTAGA AAAAGTTTTG 480

AACGATGCTT TTCTAGAAAT AAACAAAGCA TACGAAAGGC ATGCTCAGCT GTCTGCTGAT 540

GCAACTCTGA TGAACTCTGG GACCACTGCA ACGGTGGCCC TGCTGCGGGA TGGTATTGAG 600

CTGGTAGTGG CAAGTGTGGG TGACAGCCGT GCCCTGCTGT GTCGAAAAGG AAAGGCCATG 660

AAACTCACCA TTGACCATAC ACCAGAAAGG AAGGAGGAGA AGGAAAGGAT TAGGAAGTGT 720

GGTGGCTTCG TTGCCTGGAA CAGTTTGGGA CAACCTCATG TGAATGGTAG ACTTGCAATG 780

ACGCGGAGCA TAGGAGATTT GGATCTTAAA AACAGTGGTG TGATAGCCCA GCCAGAAACA 840

AAAAGGGTTC AGTTGCACCA TGCAGATGAC GGCTTCCTAG TCCTTACTAC AGACGGTATT 900

AACTTCATGG TGAACAGTCA AGAGATCTGC GACTTCATCA ACCAGTGCCA CGATCCCGCT 960

GAAGCCGCCC ACGTTGTTAC TGAGCAGGCA ATGCAGTATG GCACTGAAGA TAATAGCACG 1020

GTTGTCATAG TGCCATTTGG AGCGTGGGGA AAGTATAAAA ATGGCGAGAT CAACTTTTCC 1080

TTCAGCCGCA GTTTCGCCTC CAGTGGGAGA TGGGCGTGA 1119

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         +vg++s  g+r+e ed++++    ++ +e    + +f+vyDGhgg  +a+fc++++++++

Q: 94    KVGCASHIGKRKENEDRFDY----AQLTE---DVLYFAVYDGHGGAAAADFCAKNMERYI  146

         57999999999999999976....33322...289*************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidk....sGstavvalikds.k  116

         +e       +e++++k+l++aFl++ ++++   + s d  +    sG+ta+val++d  +

Q: 147   KEFAV----QEENLEKVLNDAFLEINKAYERHAQLSAD--AtlmnSGTTATVALLRDGiE  200

         **976....9*******************444444333..24688*************9*

S: 117   lyvanvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkd.ga.RvlGvLav  174

         l+va vGdSra+Lcr+gka++l+ dH+p+r++E+eRi++ gg v+ ++ g+ +v+G La+

Q: 201   LVVASVGDSRALLCRKGKAMKLTIDHTPERKEEKERIRKCGGFVAWNSlGQpHVNGRLAM  260

         ********************************************98889999********

S: 175   sRalGdlylk.pyvtpePevtshrltsede.fliLasDGlwdvvsneeavslvrdvlekk  232

         +R++Gdl+lk + v+++Pe+  ++l++ d+ fl+L +DG+  +v+++e++++++++++

Q: 261   TRSIGDLDLKnSGVIAQPETKRVQLHHADDgFLVLTTDGINFMVNSQEICDFINQCHD--  318

         **********555*********************************************..

S: 233   eaeqeaakkLvklalargskdnvsaivv  260

           + eaa+ ++++a+++g++dn ++++v

Q: 319   --PAEAAHVVTEQAMQYGTEDNSTVVIV  344

         ..*********************88775

Domain Sequence
(FASTA)

KVGCASHIGK RKENEDRFDY AQLTEDVLYF AVYDGHGGAA AADFCAKNME RYIKEFAVQE 60

ENLEKVLNDA FLEINKAYER HAQLSADATL MNSGTTATVA LLRDGIELVV ASVGDSRALL 120

CRKGKAMKLT IDHTPERKEE KERIRKCGGF VAWNSLGQPH VNGRLAMTRS IGDLDLKNSG 180

VIAQPETKRV QLHHADDGFL VLTTDGINFM VNSQEICDFI NQCHDPAEAA HVVTEQAMQY 240

GTEDNSTVVI V 251

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005739	; C:mitochondrion
GO:0046872	; F:metal ion binding
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0006470	; P:protein dephosphorylation

KEGG

mgp:100546141

;

InterPros

IPR001932	; PP2C-like.
IPR000222	; PP2C_Mn2_Asp60_BS.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481

; PP2C; 1.

SMARTs

SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

PS01032

; PP2C; 1.

Prints

Created Date

20-Feb-2013