EKS-MEG-00263

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MEG-00263

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	317.0	7.5E-95	27	277	251

Status

Unreviewed

Ensembl Protein

ENSMGAP00000009441

UniProt Accession

G1NAB2;

Protein Name

Protein Synonyms/Alias

Gene Name

TAOK3

Gene Synonyms/Alias

TAOK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMGAG00000009122	ENSMGAP00000009441	ENSMGAT00000010263

Organism

Meleagris gallopavo

Functional Description

Protein Length

900

Protein Sequence
(FASTA)

MRKGVPKDPE IADLFYKDDP EEIFVGLHEI GHGSFGAVYF ATNSHTNEVV AVKKMSYSGK 60

QTNEKWQDII KEVKFLQQLK HPNTIEYKGC YLKEHTAWLV MEYCLGSASD LLEVHKKPLQ 120

EVEIAAITHG ALQGLAYLHS HCKIHRDIKA GNILLTEPGQ VKLADFGSAS IVSPANSFVG 180

TPYWMAPEVI LAMDEGQYDG KVDVWSLGIT CIELAERKPP LFNMNAMSAL YHIAQNDSPT 240

LQSNEWSDSF RGFVDYCLQK IPQERPSSAD LLRHDFVRRD RPPRVLIDLI QRTKDAVREL 300

DNLQYRKMKK ILFQETRNGP LTESQEEEED SEHGSNLSRK MDSLGSNHSI PSMSVSTGSQ 360

SSSVSSMQEV LDESSPELVM MHSDESTINS TSSVVQKKDR IFIQEDSQVG HGYTKPVLVT 420

QWDVVDQALH YRNRERFATI KSASLVTRQI HEHEQENELR EQMSGYKRMR RQHQKQLIAL 480

ENKLKAEMDE HRLKLQKEVE THANNSSIEL EKLAKKQVAV MEKEAKTAAA DEKKFQQQIL 540

AQQKKDLATF LESQKKQYKL CKEKIKEEMN EDHSTPKKEK QERISKHKEN LQHTQAEEEA 600

HLLSQQRLYY DKNCRFFKRK TMIKRHELEQ QNIREELNKK RTQKEMEHAM LIRHDESTRE 660

LEYRQLHTLQ KLRMDLIRLQ HQTELENQLE YNKRRERELH RKHFMELRQQ PKNLKAMEMQ 720

IKKQFQDTCK VQTKQYKALK NHQLEVTPKS EHKTILKSLK DEQTRKLAIL AEQYEQSINE 780

MMASQALRLD EAQEAECQAL RLQLQQEMEL LNAYQSKIKM QTEAQHEREL QKLEQRVSLR 840

RAHLEQKIEE ELAALQKERS ERIKFLLERQ EREIETFDME SLRMGFGNLV TLDYPKEDYR 900

Nucleotide Sequence
(FASTA)

ATGCGCAAAG GGGTGCCAAA GGACCCAGAA ATAGCTGACC TGTTCTACAA AGATGATCCT 60

GAAGAAATAT TTGTGGGTTT ACATGAAATC GGACATGGAA GTTTTGGAGC GGTTTACTTT 120

GCTACGAATT CCCACACTAA TGAGGTGGTG GCAGTCAAGA AGATGTCCTA CAGCGGCAAG 180

CAAACCAATG AGAAATGGCA GGATATCATC AAAGAAGTCA AGTTTCTGCA ACAACTGAAG 240

CACCCAAACA CCATAGAATA TAAGGGCTGT TACCTGAAGG AGCATACAGC ATGGTTGGTT 300

ATGGAGTACT GTTTAGGATC AGCTTCTGAT TTGCTAGAAG TTCACAAGAA ACCACTTCAG 360

GAAGTGGAGA TTGCTGCCAT CACCCACGGT GCCTTGCAGG GGCTGGCCTA CCTGCACTCT 420

CACTGTAAGA TACACAGGGA CATTAAAGCT GGAAATATTC TTCTAACAGA ACCGGGTCAA 480

GTAAAGCTAG CTGATTTTGG GTCTGCATCT ATAGTCTCCC CTGCCAATTC CTTTGTAGGA 540

ACACCTTACT GGATGGCACC AGAGGTGATC CTTGCTATGG ATGAAGGACA GTACGATGGG 600

AAGGTGGATG TCTGGTCTCT TGGGATCACA TGTATTGAGT TAGCTGAAAG GAAGCCTCCG 660

CTTTTCAACA TGAATGCAAT GAGTGCCTTA TATCACATAG CCCAGAACGA TTCCCCTACC 720

TTACAGTCGA ACGAATGGTC AGACTCCTTT AGGGGATTTG TTGATTACTG CTTACAGAAA 780

ATACCTCAGG AAAGGCCATC ATCAGCAGAT CTACTACGGC ACGATTTTGT TCGCCGAGAT 840

CGACCACCGA GAGTCCTCAT AGACCTCATA CAGAGGACAA AAGATGCAGT ACGAGAACTG 900

GATAACCTTC AGTACAGGAA AATGAAGAAA ATCCTTTTCC AAGAGACGCG GAACGGCCCT 960

CTGACTGAGT CTCAAGAAGA GGAGGAGGAC AGTGAGCATG GATCAAACCT GAGTAGGAAG 1020

ATGGACAGTC TGGGCAGCAA CCATTCCATC CCAAGCATGT CTGTGAGCAC AGGCAGTCAG 1080

AGCAGCAGTG TGAGCAGCAT GCAGGAGGTC CTGGATGAGA GCAGCCCTGA ACTGGTCATG 1140

ATGCATAGTG ACGAGAGCAC AATTAATTCC ACTTCCTCCG TTGTTCAGAA GAAGGACAGA 1200

ATTTTTATTC AGGAAGACTC TCAAGTTGGT CATGGCTACA CCAAGCCTGT GCTGGTGACC 1260

CAGTGGGACG TGGTGGATCA GGCCCTCCAC TACCGGAACC GAGAGCGCTT TGCCACGATC 1320

AAATCAGCAT CTTTGGTTAC AAGGCAGATC CATGAGCATG AGCAGGAGAA CGAGTTGCGG 1380

GAACAGATGT CAGGATATAA GCGGATGCGG CGCCAGCACC AGAAGCAGCT GATCGCCCTG 1440

GAAAACAAGT TGAAGGCCGA GATGGACGAG CACCGCCTCA AGCTGCAGAA GGAGGTGGAG 1500

ACACATGCCA ACAACTCGTC CATTGAGCTG GAGAAGCTGG CCAAGAAGCA AGTGGCTGTG 1560

ATGGAGAAGG AGGCAAAGAC AGCTGCAGCA GATGAAAAGA AATTCCAGCA ACAGATTTTG 1620

GCTCAGCAAA AGAAAGACCT GGCGACCTTT TTAGAAAGTC AGAAGAAACA ATACAAGCTT 1680

TGCAAGGAAA AGATTAAAGA GGAAATGAAC GAGGACCACA GCACACCGAA GAAAGAGAAG 1740

CAGGAAAGAA TATCCAAACA CAAAGAGAAC CTGCAGCACA CACAGGCTGA AGAGGAGGCC 1800

CATCTTCTCA GCCAGCAGAG ACTCTACTAC GACAAAAACT GCCGTTTCTT CAAGAGAAAA 1860

ACGATGATCA AGAGGCACGA GTTGGAGCAG CAGAACATTC GGGAAGAGTT GAACAAGAAG 1920

CGGACCCAGA AAGAAATGGA GCACGCCATG CTGATCCGGC ACGACGAGTC GACGCGTGAG 1980

CTGGAATACA GGCAGCTACA CACGCTGCAG AAGCTGCGAA TGGACCTGAT CCGGCTGCAG 2040

CACCAGACTG AGCTTGAGAA TCAGCTGGAA TACAACAAGC GACGAGAGCG GGAGCTGCAC 2100

AGGAAGCATT TCATGGAGCT CCGGCAGCAA CCAAAGAACC TGAAGGCTAT GGAAATGCAG 2160

ATCAAAAAGC AGTTCCAGGA CACGTGCAAA GTGCAAACTA AGCAGTACAA AGCACTGAAG 2220

AATCACCAGC TGGAAGTAAC TCCAAAGAGT GAGCACAAGA CAATTTTGAA GAGTCTGAAG 2280

GACGAGCAGA CGAGGAAGCT CGCCATCCTG GCGGAGCAGT ACGAGCAGAG CATCAACGAG 2340

ATGATGGCCT CGCAAGCGCT GCGACTGGAC GAGGCCCAAG AAGCAGAATG CCAAGCCCTG 2400

AGACTGCAAC TCCAGCAGGA GATGGAGCTC CTCAACGCGT ACCAGAGCAA AATTAAGATG 2460

CAGACAGAAG CACAGCACGA AAGAGAACTC CAGAAGCTGG AGCAGAGGGT GTCACTGCGC 2520

AGGGCACATC TGGAACAAAA GATTGAAGAG GAGCTCGCCG CCCTCCAGAA GGAACGCAGC 2580

GAGAGGATCA AGTTTCTGTT GGAAAGGCAG GAGCGAGAGA TTGAAACGTT TGACATGGAG 2640

AGCTTACGAA TGGGCTTTGG GAATTTGGTC ACATTAGATT ATCCCAAGGA GGACTATAGA 2700

TGA 2703

Domain Profile

S: 4     leeigkGalgkvylarekktgelvaikkinlekq...ekleelqkeisvlkklkhpnive  60

         l+eig+G++g+vy a++ +t+e+va+kk++++ +   ek+++++ke+++l++lkhpn +e

Q: 27    LHEIGHGSFGAVYFATNSHTNEVVAVKKMSYSGKqtnEKWQDIIKEVKFLQQLKHPNTIE  86

         689****************************988899***********************

S: 61    ylesflkeeelwlvmeylagGslsdlvkeelkselkEeqiayilrevlkaLeylHskkvi  120

         y +++lke++ wlvmey+  Gs+sdl++ ++k++l+E +ia+i++++l++L+ylHs+ +i

Q: 87    YKGCYLKEHTAWLVMEYCL-GSASDLLE-VHKKPLQEVEIAAITHGALQGLAYLHSHCKI  144

         ******************7.********.*******************************

S: 121   HrdikakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaqe.ekgYde  179

         Hrdika+niLlte g+VkL+dfg+a+ ++      +++vgtpywmAPEvi ++ e +Yd

Q: 145   HRDIKAGNILLTEPGQVKLADFGSASIVSP----ANSFVGTPYWMAPEVILAMdEGQYDG  200

         *************************99999....69**************9887999***

S: 180   kaDiwslGItaielaegepPfkdleplkallkilkneppklkskkkfskefkefvekclq  239

         k+D+wslGIt+ielae++pP++++++++al++i++n++p+l+s+ ++s++f+ fv+ clq

Q: 201   KVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNDSPTLQSN-EWSDSFRGFVDYCLQ  259

         *****************************************888.***************

S: 240   knpekRpsasellkhkFl  257

         k p++Rps+++ll+h F+

Q: 260   KIPQERPSSADLLRHDFV  277

         ****************97

Domain Sequence
(FASTA)

LHEIGHGSFG AVYFATNSHT NEVVAVKKMS YSGKQTNEKW QDIIKEVKFL QQLKHPNTIE 60

YKGCYLKEHT AWLVMEYCLG SASDLLEVHK KPLQEVEIAA ITHGALQGLA YLHSHCKIHR 120

DIKAGNILLT EPGQVKLADF GSASIVSPAN SFVGTPYWMA PEVILAMDEG QYDGKVDVWS 180

LGITCIELAE RKPPLFNMNA MSALYHIAQN DSPTLQSNEW SDSFRGFVDY CLQKIPQERP 240

SSADLLRHDF V 251

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005739	; C:mitochondrion
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0031572	; P:G2/M transition DNA damage checkpoint
GO:0000165	; P:MAPK cascade
GO:0046329	; P:negative regulation of JNK cascade
GO:0046330	; P:positive regulation of JNK cascade
GO:0043507	; P:positive regulation of JUN kinase activity
GO:0046777	; P:protein autophosphorylation

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013