EKS-MEG-00267

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MEG-00267

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	308.9	2.2E-92	27	293	267

Status

Unreviewed

Ensembl Protein

ENSMGAP00000010667

UniProt Accession

G1NCZ0;

Protein Name

Protein Synonyms/Alias

Gene Name

MYO3B

Gene Synonyms/Alias

MYO3B;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMGAG00000010257	ENSMGAP00000010667	ENSMGAT00000011528

Organism

Meleagris gallopavo

Functional Description

Protein Length

1125

Protein Sequence
(FASTA)

RKPLYGLFQY NSSMIGLESL ADPTDTWEII ETIGKGTYGK VYKVANKKDG SLAAVKILDP 60

ISDVDEEIEA EYNILQFLPN HPNVVRFYGM FYKADIYVGG QLWLVLELCN GGSVTELVKG 120

LLKCGQQLDE AMISYILYGA LLGLQHLHNN RIIHRDVKGN NILLTTEGGV KLVDFGVSAQ 180

LTSTRLRRNT SVGTPFWMAP EVIACEQQYD YSYDARCDVW SLGITAIELG DGDPPLFDMH 240

PVKTLFKIPR NPPPTLLHPE KWCRGFNHFI SQCLIKDFEK RPTVTHLLEH PFIKQVHGKD 300

MSLQKQLAEL IQEQQRLGSV AKTRHERIHT RRPYHVDGAD KYSQDDDLVN LEVLDEDTII 360

HQLQKRYADL QIYTYVGDIL IALNPFQNLN IYSPQFSKLY HGMKRSSNPP HIFASADAAY 420

QSMVTFSKDQ CIIISGESGA GKTESAHLIV QHLTFLGKAN NRALREKILQ VNPLVEAFGN 480

ACTAINDNSS RFGKYLEMMF TPTGAVMGAK ISEYLLEKSR VIKQAVGEKN FHIFYYIYAG 540

LYHQKKLSEY RLPEKKPPRY IDNETGRVMH DIVTKDSYGR QFEAIQHCFK SIGFTDEEVY 600

SVYRILTGIL NTGNIEFAAI SSQHQTDKSE VPNPEALDNA AALLSIGSEE LQEALTSHCV 660

VTRGETIIRT NTVDKAADVR DAMSKALYGR LFSWIVNRIN TLLQPDKNIC NTENGMNVGI 720

LDIFGFENFA RNSFEQLCIN IANEQIQFYF NQHIFALEQM EYQNEGIDAA TVEYEDNRPL 780

LDMFLQKPMG LLSLLDEESR FPQATDLTLV DKFEDNLRCK YFWRPKGVEL SFGIQHYAGK 840

VLYDASAFLE KNRDTLPADI VVVLRTSENK LLQQLFSSPL TKTGNLAQAR ARVTAASRSL 900

PPQLSAGRIK VDTMEVMRHP EETTNMKRQT MASYFRYSLM DLLSKMVVGQ PHFIRCIKPN 960

DDREALTFSH ERVLLQLRYT GILETVKIRQ KGYSHRILFE EFVKRYYYLA FKAHESPLGS 1020

RENCLTILEK AKLENWILGK TKVFLKYYHI EQLNLFLREV IGRVVVMQAY IKGWLGARRY 1080

KKAKEKRENS AVTIQSAWRG YEARRKYKEI RNRRNNAAIH IQAGN 1125

Nucleotide Sequence
(FASTA)

AGGAAGCCGT TGTATGGATT ATTTCAATAC AATTCTAGTA TGATCGGACT AGAATCATTA 60

GCTGATCCCA CAGACACCTG GGAAATTATA GAAACTATTG GAAAAGGCAC TTATGGTAAA 120

GTCTATAAGG TTGCCAATAA GAAAGATGGG AGTCTGGCAG CAGTAAAGAT TCTCGATCCT 180

ATTAGTGATG TGGATGAAGA AATTGAAGCA GAATATAATA TTTTGCAGTT TCTTCCCAAT 240

CATCCTAATG TTGTTAGATT TTATGGGATG TTCTACAAAG CAGATATATA TGTGGGAGGA 300

CAGCTCTGGC TAGTACTTGA GCTGTGCAAT GGAGGGTCTG TCACAGAACT TGTCAAAGGT 360

TTGCTGAAGT GTGGCCAACA ATTGGATGAA GCTATGATCT CATACATCTT ATATGGTGCT 420

CTCTTGGGCC TTCAGCATTT ACACAATAAC CGGATCATTC ATCGAGATGT CAAAGGGAAC 480

AACATTCTTC TGACAACAGA AGGTGGAGTC AAGCTCGTTG ACTTCGGTGT TTCAGCCCAG 540

CTCACCAGCA CACGGCTACG TAGAAACACC TCAGTGGGAA CACCCTTCTG GATGGCTCCT 600

GAGGTCATTG CTTGTGAACA GCAATATGAC TACTCATATG ATGCTCGATG TGACGTATGG 660

TCTTTGGGAA TAACAGCTAT TGAACTCGGT GATGGAGACC CTCCTTTATT TGACATGCAT 720

CCAGTGAAAA CTCTTTTTAA AATTCCAAGA AACCCTCCTC CTACTTTGCT GCACCCTGAA 780

AAATGGTGCA GAGGATTCAA CCATTTCATT TCACAGTGTC TTATCAAGGA TTTCGAGAAA 840

CGTCCTACAG TCACCCACCT TTTGGAGCAT CCATTTATTA AACAAGTGCA TGGTAAAGAT 900

ATGTCTCTGC AAAAACAGTT GGCTGAGCTT ATCCAAGAAC AGCAGCGACT AGGCTCTGTA 960

GCAAAAACAA GGCATGAACG AATACATACC AGAAGACCCT ACCATGTGGA TGGTGCTGAC 1020

AAGTACTCTC AAGATGATGA TCTGGTAAAT CTAGAAGTTC TTGATGAGGA TACAATTATA 1080

CATCAGCTGC AGAAACGCTA TGCCGACTTA CAAATTTATA CGTATGTTGG AGATATTTTG 1140

ATAGCCTTAA ACCCTTTCCA GAATCTCAAC ATTTACTCTC CACAGTTCTC CAAGCTTTAC 1200

CATGGTATGA AGCGCTCATC CAATCCCCCC CACATATTTG CCTCTGCAGA TGCTGCCTAC 1260

CAAAGTATGG TGACGTTCAG CAAAGATCAG TGCATTATCA TCAGTGGGGA AAGTGGTGCT 1320

GGAAAGACAG AAAGTGCCCA TTTGATCGTC CAACATTTGA CCTTCTTGGG AAAGGCCAAT 1380

AATCGTGCTT TGCGTGAGAA AATACTTCAG GTGAATCCTC TGGTTGAAGC ATTTGGGAAT 1440

GCCTGCACTG CCATCAATGA CAACTCAAGT CGCTTCGGAA AATATCTGGA AATGATGTTT 1500

ACACCCACAG GAGCTGTAAT GGGGGCAAAG ATTTCTGAGT ATCTACTTGA AAAGTCAAGG 1560

GTTATAAAAC AGGCTGTGGG AGAGAAAAAT TTCCATATAT TTTATTATAT TTATGCTGGC 1620

CTTTATCATC AGAAGAAACT TTCTGAATAT AGGCTTCCTG AAAAAAAGCC TCCTAGATAC 1680

ATTGATAATG AAACTGGAAG AGTAATGCAC GATATTGTTA CTAAGGATTC CTATGGAAGG 1740

CAATTTGAAG CAATTCAGCA TTGCTTTAAA AGTATAGGAT TCACTGATGA GGAAGTGTAT 1800

TCAGTGTACA GAATTCTGAC TGGTATCTTA AATACTGGAA ACATTGAGTT TGCTGCCATT 1860

TCTTCACAAC ACCAAACAGA TAAAAGTGAA GTTCCAAACC CAGAAGCCTT AGATAATGCT 1920

GCTGCACTGC TAAGTATTGG GTCAGAAGAA CTGCAAGAGG CCCTAACCTC CCACTGTGTT 1980

GTAACACGGG GGGAGACTAT TATTCGAACA AACACTGTGG ACAAAGCAGC TGACGTGCGA 2040

GATGCCATGT CTAAAGCGCT TTATGGCAGA CTCTTCAGCT GGATCGTAAA TCGTATTAAT 2100

ACACTTCTTC AGCCAGATAA AAATATATGC AATACTGAAA ATGGAATGAA TGTTGGTATA 2160

CTAGATATAT TTGGATTCGA GAACTTCGCA AGAAATTCCT TTGAACAGCT GTGCATAAAT 2220

ATTGCTAATG AGCAGATCCA GTTTTATTTC AATCAACATA TTTTTGCACT TGAACAGATG 2280

GAATATCAGA ATGAGGGAAT TGATGCTGCT ACAGTGGAGT ATGAAGACAA CCGTCCACTT 2340

CTGGATATGT TCCTCCAGAA ACCCATGGGT CTCCTTTCTC TACTAGATGA AGAAAGTCGA 2400

TTTCCTCAGG CAACAGACCT AACATTAGTT GATAAATTTG AGGATAATTT ACGATGCAAA 2460

TACTTCTGGA GACCAAAAGG AGTGGAATTG TCATTTGGTA TTCAGCACTA TGCTGGAAAG 2520

GTATTGTATG ATGCCTCCGC ATTTCTTGAG AAGAATAGGG ATACTCTTCC TGCTGACATA 2580

GTGGTGGTGC TGAGAACCTC AGAGAACAAA CTTCTTCAGC AGCTGTTTTC TAGCCCACTA 2640

ACCAAAACAG GTAACTTGGC ACAGGCAAGA GCCAGAGTGA CAGCAGCATC TAGGTCTTTG 2700

CCTCCACAGC TTAGTGCTGG GCGTATCAAG GTTGACACAA TGGAGGTTAT GCGGCACCCT 2760

GAGGAAACAA CTAACATGAA GCGACAAACT ATGGCTTCCT ATTTTAGGTA TTCACTCATG 2820

GATCTTCTAT CCAAAATGGT TGTTGGACAA CCTCACTTTA TCCGCTGCAT TAAACCTAAT 2880

GATGATCGAG AAGCACTAAC ATTTTCTCAT GAGAGAGTTC TACTGCAGCT ACGATACACT 2940

GGAATTCTGG AAACTGTCAA AATACGTCAA AAAGGATATT CTCATCGCAT CCTTTTTGAA 3000

GAGTTTGTGA AAAGGTATTA CTACCTTGCA TTCAAGGCAC ATGAGTCTCC CCTTGGCAGC 3060

AGAGAAAACT GTCTGACCAT TTTGGAGAAA GCTAAACTAG AAAACTGGAT TCTTGGAAAA 3120

ACCAAGGTTT TTCTGAAGTA TTACCATATA GAGCAGTTAA ATTTGTTCCT GCGAGAAGTT 3180

ATAGGGAGGG TGGTGGTCAT GCAGGCTTAT ATCAAGGGAT GGCTTGGAGC AAGGAGGTAC 3240

AAGAAAGCCA AAGAAAAAAG AGAAAATAGT GCTGTTACCA TACAGTCAGC TTGGAGAGGA 3300

TATGAAGCTC GCAGGAAGTA CAAGGAAATA AGGAACAGAA GAAATAATGC TGCTATACAT 3360

ATTCAAGCAG GTAATTAA 3378

Domain Profile

S: 1     yelleeigkGalgkvylarekktgelvaikkinlekqekleelqkeisvlkkl.khpniv  59

         +e++e+igkG++gkvy+  +kk g+l+a+k+++  + +  ee++ e+++l+ l +hpn+v

Q: 27    WEIIETIGKGTYGKVYKVANKKDGSLAAVKILDPIS-DVDEEIEAEYNILQFLpNHPNVV  85

         799******************************998.9999**********98356****

S: 60    eylesflk.....eeelwlvmeylagGslsdlvk..eelkselkEeqiayilrevlkaLe  112

         +++++f+k       +lwlv+e+++gGs+++lvk   ++ ++l+E  i+yil ++l +L+

Q: 86    RFYGMFYKadiyvGGQLWLVLELCNGGSVTELVKglLKCGQQLDEAMISYILYGALLGLQ  145

         *******99999999*******************877899********************

S: 113   ylHskkviHrdikakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaq  172

         +lH++++iHrd+k++niLlt+eg VkL+dfgv+aql++tr +r+t vgtp+wmAPEvia+

Q: 146   HLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIAC  205

         ************************************************************

S: 173   e...ekgYdekaDiwslGItaielaegepPfkdleplkallkilkneppklkskkkfske  229

         e   + +Yd+++D+wslGItaiel +g+pP++d++p+k l+ki++n+pp+l +++k+++

Q: 206   EqqyDYSYDARCDVWSLGITAIELGDGDPPLFDMHPVKTLFKIPRNPPPTLLHPEKWCRG  265

         9777779*****************************************************

S: 230   fkefvekclqknpekRpsasellkhkFl  257

         f++f+++cl k++ekRp++++ll+h+F+

Q: 266   FNHFISQCLIKDFEKRPTVTHLLEHPFI  293

         ***************************7

Domain Sequence
(FASTA)

WEIIETIGKG TYGKVYKVAN KKDGSLAAVK ILDPISDVDE EIEAEYNILQ FLPNHPNVVR 60

FYGMFYKADI YVGGQLWLVL ELCNGGSVTE LVKGLLKCGQ QLDEAMISYI LYGALLGLQH 120

LHNNRIIHRD VKGNNILLTT EGGVKLVDFG VSAQLTSTRL RRNTSVGTPF WMAPEVIACE 180

QQYDYSYDAR CDVWSLGITA IELGDGDPPL FDMHPVKTLF KIPRNPPPTL LHPEKWCRGF 240

NHFISQCLIK DFEKRPTVTH LLEHPFI 267

Keyword

ATP-binding; Complete proteome; Motor protein; Myosin; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0016459	; C:myosin complex
GO:0005524	; F:ATP binding
GO:0003774	; F:motor activity
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000048	; IQ_motif_EF-hand-BS.
IPR011009	; Kinase-like_dom.
IPR001609	; Myosin_head_motor_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00612	; IQ; 1.
PF00063	; Myosin_head; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00015	; IQ; 2.
SM00242	; MYSc; 1.
SM00220	; S_TKc; 1.

Prosites

PS50096	; IQ; 2.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR00193

; MYOSINHEAVY.

Created Date

20-Feb-2013