EKS-MEG-00073

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MEG-00073

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	359.4	1.6E-107	3651	3998	348

Status

Unreviewed

Ensembl Protein

ENSMGAP00000018371

UniProt Accession

G1NE83;

Protein Name

Protein Synonyms/Alias

Gene Name

PRKDC

Gene Synonyms/Alias

PRKDC;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMGAG00000010711	ENSMGAP00000018371	ENSMGAT00000020266
ENSMGAG00000010711	ENSMGAP00000017973	ENSMGAT00000020076
ENSMGAG00000010711	ENSMGAP00000011213	ENSMGAT00000012083

Organism

Meleagris gallopavo

Functional Description

Protein Length

4060

Protein Sequence
(FASTA)

QFRECREEAL KFLCVFLEKI GERVHPYACS LKQTCISVYT KERAAKCKIP ALELLIKLLQ 60

SLRRSCLMEE MKVGEIFNKF YGELAVRSRV SDTVLEKIYE LLGVLGEVHP TDMINNSEKL 120

FRAYLGELKT QMTSATRVPK LPVVAGCLRG LTALMYNFTK SMDEDAQTSK EIFDFAVKAI 180

RPQVDQKRYA VHLAGLQLFS WHAAQFGTLL LDSYVMLFET MCRWCGHTNQ ELKKAGHNAL 240

DSFLKQMSLM VAKDAELHRS KLKFFMEQFY GIIRRMDSSN KELSIAIRGY GLFAAPCKAI 300

HPADVDAMYV ELLQRCKQMY LTEAETMDDH LYQLPSFLQS IASVIFHLDA IPEVYTPVLE 360

HLVVLQINSF PQYSEKMQLV CCRSIIKVFL ALSIKGPVLW SFIGTVVHQG LIRVFSKPMT 420

FSKDVFRKET SGSEDFPEAG EVETAKWKVP TYKDYLYLFR SLLSCDTMKE SIFEEENFLT 480

GNSPLQSLNR LLYDELIKSI LKIIEKLDLT VQKLNVHEQD ESETDNAFIG PTSDPASNLQ 540

PKKPTDFIAF INLVEFCRDI LPDKHVEYFQ PWVYSFGYEL IVHSTRLPVI SGFYNLLSVT 600

MKIAKKIKYF EGVSPRSLRK ATEDPEKNSC FALFAKFGKE VTAKMKQYKD ELLASCLNFL 660

LSLPHDIIML DIKAYIPALQ NAFKLGLSCT PMADLGLDAL EDWSAHIPRH IMQPYYKDVL 720

PLLDGYLKNS ATAVEPQNNW EVRKLSRAAQ KGFNKIVIQR LRKAKTSSLD DSPSLEGVRT 780

RVARLLGSLG GQINHNLITA TSAEEMMKKC VSWDTENHLS FAVPFADMKP VIYLDVFLPR 840

VTDLALSASD RQTKVAACEL LHSIVAYMLG KASQMPERQQ GSPPMYQLYK RIFPVLLRLA 900

CDVDQVTRQL YEPLVMQLIH WFTNNKKFES QDTVTFLEAI LSGIVDPVDS TLRDFCGQCV 960

REFLKWSIKQ TTPRQQEKSP ANTKSLFKRL YSLALHPSAF KRLGAALAFN SIYREFREEN 1020

SLVEQFVFEA LVVFLESLAL THTDEKSLGT TQQCCDAINH LKRIIKHKAP ALNKEGKRRV 1080

PRGFPATKSV CLQDVVMWLL VQCGRPQTEC RHKAMELFYE FVPLLPGNNS PSSWLADVLK 1140

KKDVSFLINK FEGGGSDAES PSGILSQPTL RNMQEPFSLP TVMRWMDMFL AALDCYNTFF 1200

ELRMIKPHEI LGVNDRSSFL EAVDFFLETI ALHDIHAVER CFDCRLRGNI FSPQEREMYN 1260

YSKCTIIVRI MEFVTMILET CQQDFWKLLE KELLNANFVE LLVMTVCDPS HIGFNTADVQ 1320

VMKNLPDISV RLLKALMKSP CKEYLQLCLR KRITPQSFED LFSVDLFNSD ERFDQVRFSA 1380

VLSACKQLQK SGLLHSVLHN QGERPHPSIG SKLLSVVYKG IAPGSERSSL PAVDISSKRL 1440

ADRLLQLAFA IDDQCEELVS LLLNTVVLSV PLSEASERNF VNFSHGQYFY SLFSDTINQQ 1500

LLKNLDVIVI QLMESSVSNP QMVGSILNGM LDQSFRERTI RKQQGVKLVT AVLRNWKRLD 1560

SWWAKDSPSK TRIAIYVLSV HSLQIDSSVS FNTSHEAFTA VFDTYTSLLT DQNLGLNLKG 1620

QAVIILPFFT NLTGEKLNEL KNALDQLVAF NFPMSSDEFP RGTLKHNNYV DCTKKFLDAL 1680

ELSQSPMLLQ LMTEILCRDH RHSMEDLFQA SFKRISRRSS TDKQVVLLDT VHKMFQNEDL 1740

LSNTVRQAFV DRSLLTLMSH CSLDALREFF CKIIVQAMDT LNSRFTKSNE CVFDTQITKK 1800

MGYYKLLEVM YIRLSKEDVH SKDSKINQAY RGSVSVEGNE LTKALIKLCY DAFTENMAGE 1860

SQLLEKRRQY HCAAYNCAIA VISCVFTESK FYQGFLFTEK SEKNLLIFEN LIDLKRQYMF 1920

PVEIEVPLER KKRYIAIRKE AREAWNDGQD EPKYLASASY MMDSSLSEEM SQFDFSTGVQ 1980

GFSYSSQDVT ASSAHFRRKE MSEYMVLNDE LELEMDELNQ HECMAPMTTL IKHMQRNQIT 2040

PKVEEGVVPV DLPLWMKFLH SKLGNPSVPL NIRLFIAKLI VNTEDVFRPY AKQWLGPMLQ 2100

LVVSGNNGGE GIHFMVVEIA VTVLSWTSVN TPKGNIKDEI LANRLLEFLM KNAFHQKRAV 2160

FRHNLEIIKT VIECWKNCLS IPYSLIFEKF SSEDPDTKDN SVGIQLLGIV LANNLPPYDL 2220

KCEIDRVRYF QALISNMGLL RYKEVYAAAA EVLGLALQYI AERQNILEDP VYDCVIKQLK 2280

HHQNTQQDKF IICLNKVVKN FPPLADRFMN AVFFLIPKLH GVMKNYCLEV IMYRAEEIPD 2340

LYLQLKSKDF IQIMKHRDDE RQRVCLDIIY KMLSTLKPPE LKELLPGVTG FISHPSVICR 2400

QRMYDILMWI YDNYSDPESQ AGDDSQEVHG LAKETLLQGL IDENAELQLI VRNFWSDETR 2460

LPANILDRML KLLSSLYSAK IETQYLSLIT NFLLEMTSKS PDYSRKIFEH PLSECKFQDF 2520

VIDSSWRYRS TILTPMFVET QASQSTNRNS SQEKSLSISG SVGGRVRATQ RQYEFTPTQN 2580

VGGRSSFNWL TGNSIDTLAE YTVPSSSESL SSSMLLVNKR SEKFKPVGPD FGKKRLSLPG 2640

DKVNSKTKGI DERAEILRLR RRFLKDQEKV SLIYARKGVA EQKREKEMKS ELKMKFDGQV 2700

TLYRNYRVGD LPDIQIEHSS LIAPLQALAQ KDPTFAKQLF SSLFAGIFHE VKKSKTLSEK 2760

KVIIQKLLKD FNHFLSTSLS YFPPFIACIQ EISYKHRELL ELDSAIVSTS CLASLQQPVG 2820

ILLLEHALMA LSPAEEPPSK RMRGRMELPP DVIKWLELAK LYRSLGDYDV LRGIFSGKIG 2880

TKKITQQALL AEARSDYAEA AKCYDEALSK EDWEDGDPTE AEKDFWEHAS LECYDHLTEW 2940

KSLEYCATVN IDSGKPPDLS KTWNDPFYQE TYLPYIIRSK LKLLLSGEND QTLLTFIDEA 3000

MKTEQKKALI EMHYSQELSL LYILQDDFDR AKYYIGNGMQ IFMQSYSSID TLLYQSRMSK 3060

LQSVQALTEI QDFINFMTKT SNLTSRAKSL KRLLRTWTSR YPDAKMDPMN IWDDIITNRC 3120

FFLDKLQEKF LCDQANDSME VDEESGVGDQ MEVDQQDEDI HSMIRSCKFN MKLKMIESAR 3180

KQNSFSVAKK LLKDLRREAR TREDWLVRWN CAYCRFVHSC SQSQSCPERV LSVLKTISLL 3240

EDTKSDYLNE NIMAFRNQNL LLGSTYHIMA NALSQDPKCF EQIEEEKAGK ILELSGESSE 3300

SPEKILAGLN KRAFQYFSSA ARKSEEEVQS LSMEHIDVKG VIDAYMTLVG FCDQHLRKEE 3360

EGSLEINAAD LQLFPAIVVE QMIKALKLNS REARLRFPRL LQIIERYPAE TLGLVTRELS 3420

SVPCWQFIGW ISQMMALLDK DEAVAVQHTV EEIADTYPQA IIYPFMISSE SFCFKDTAAG 3480

CKNKEFVASI RNKLDRGGVV QDFIHSLEQL SNPVMLFKDW VEDVRNELVK AQRNKIKLRE 3540

MYERMYKNLG DAKAPGLGWL RKQFVQAFGK DFDSHFGKGG SKLLDMKASD FNEITTSLLT 3600

KMNKTHKEPA NLKECSPWMS EFRAEFLRNE LEVPGQYDGK GKPLPEYHVK ISGFDERIMV 3660

LESLRKPKRI TIRGSDEQEH PFLVKGGEDL RQDQRIEQLF DVMNIVLSRD AACSQRNMQL 3720

KTYQVIPMTT RLGLIKWLEN TCTLKEFLRN SMTEEEDTKY NSQKGPRAAY SDWLSKMGGK 3780

AQGLSRYSAM YKNASRTETV TAFRSRENSV PEDLLRRAFV KMSTSPEAFL ALRSHFASSH 3840

ALMCISHWIL GIGDRHLSNF MINKETGGMV GIDFGHAFGS ATQFLPVPEL MPFRLTRQFV 3900

NLMMPVKEWG LIYSVMVHAL RAYRADPDLL ISTMDVFVKE PSLDWKNFEQ RQLKKGGTWI 3960

KEINTAEVNW YPLQKISYVK RKLTGANPAR ITCDELHLGY EKSPFYNDFA AVARGSTDHN 4020

IRAKEPEDGL SEETQVQCLI DQATDPNVLG RVWEGWEPWM 4060

Nucleotide Sequence
(FASTA)

CAGTTTCGAG AATGCAGAGA AGAAGCGTTG AAGTTTCTCT GCGTCTTTTT GGAAAAGATT 60

GGAGAGAGAG TTCATCCTTA CGCCTGCAGC CTTAAGCAAA CTTGCATTAG TGTTTATACA 120

AAAGAGAGGG CAGCAAAATG TAAAATTCCA GCTCTGGAAC TTCTGATTAA GTTGCTCCAA 180

AGCTTACGAC GTTCCTGTCT GATGGAAGAG ATGAAAGTTG GGGAAATCTT TAATAAATTC 240

TATGGGGAGC TTGCTGTAAG AAGTAGAGTT TCTGATACAG TACTGGAGAA GATCTATGAG 300

CTTTTGGGAG TTTTGGGAGA AGTCCATCCT ACTGACATGA TTAACAACTC TGAAAAACTA 360

TTCCGAGCGT ATTTGGGAGA GCTTAAAACA CAGATGACAT CAGCTACGAG GGTCCCCAAG 420

CTACCTGTTG TAGCAGGATG CCTGAGGGGA CTGACTGCAC TCATGTACAA CTTTACCAAG 480

TCTATGGATG AAGATGCTCA AACTTCAAAG GAGATTTTTG ATTTTGCAGT GAAAGCTATC 540

AGGCCACAGG TTGATCAGAA GCGATATGCA GTACATCTAG CTGGTTTACA ATTGTTCAGC 600

TGGCATGCTG CTCAGTTTGG TACCCTGCTC TTGGACAGCT ATGTCATGCT CTTTGAAACA 660

ATGTGTAGAT GGTGTGGCCA CACAAATCAA GAGCTGAAAA AAGCTGGTCA TAATGCACTA 720

GATTCATTCC TCAAACAGAT GTCTCTAATG GTGGCAAAGG ATGCAGAGCT ACACAGGAGC 780

AAATTGAAGT TCTTCATGGA GCAGTTCTAT GGGATCATCA GAAGAATGGA TTCGAGCAAC 840

AAGGAGCTGT CCATAGCTAT TCGTGGATAT GGGCTATTTG CAGCGCCTTG CAAAGCTATA 900

CATCCTGCAG ATGTTGATGC CATGTACGTT GAGCTCCTTC AGCGCTGTAA GCAAATGTAC 960

CTCACAGAGG CAGAGACAAT GGATGACCAT CTGTATCAGC TTCCAAGTTT CCTTCAGTCC 1020

ATTGCAAGCG TGATATTCCA TTTAGACGCG ATTCCAGAAG TATACACTCC GGTTCTTGAG 1080

CATCTAGTTG TGCTACAAAT CAATAGCTTT CCACAATACA GTGAAAAAAT GCAGTTAGTC 1140

TGTTGCAGAT CAATAATAAA GGTGTTTCTA GCCCTCTCAA TAAAAGGTCC TGTTCTCTGG 1200

AGTTTTATTG GCACTGTTGT GCATCAGGGA TTAATCAGAG TATTCTCCAA GCCAATGACG 1260

TTTTCAAAGG ATGTTTTCAG AAAAGAAACT TCTGGATCAG AAGACTTCCC AGAAGCTGGA 1320

GAGGTTGAGA CAGCAAAATG GAAAGTACCA ACCTATAAGG ACTATCTGTA TCTTTTCAGA 1380

AGCTTACTGA GTTGTGACAC GATGAAGGAA TCCATTTTTG AAGAAGAAAA CTTTCTTACT 1440

GGAAATTCAC CACTGCAGTC TCTGAATCGG TTGCTATATG ATGAACTCAT AAAATCTATT 1500

TTGAAGATTA TTGAGAAGTT GGATCTGACT GTTCAGAAAC TGAATGTCCA CGAGCAGGAT 1560

GAAAGTGAAA CCGACAATGC TTTTATTGGG CCTACTTCTG ACCCTGCTTC AAACCTTCAG 1620

CCAAAGAAAC CCACAGACTT TATTGCCTTT ATAAACTTGG TAGAATTCTG CAGAGACATA 1680

CTTCCAGATA AACATGTTGA ATACTTTCAG CCTTGGGTGT ATTCCTTCGG TTACGAGCTT 1740

ATTGTACATT CAACGAGACT ACCTGTTATC AGTGGATTCT ACAATCTGCT TTCTGTTACA 1800

ATGAAGATTG CCAAGAAAAT AAAATACTTT GAGGGTGTCA GTCCAAGGAG TCTCAGAAAA 1860

GCTACTGAAG ACCCTGAAAA GAATTCTTGC TTTGCCCTGT TTGCGAAGTT TGGAAAAGAG 1920

GTTACAGCAA AAATGAAACA GTATAAAGAT GAGTTGTTGG CATCCTGTCT AAATTTTTTA 1980

CTCTCTTTAC CCCATGACAT CATCATGCTT GATATCAAAG CATATATTCC TGCACTGCAG 2040

AATGCATTTA AGCTGGGCCT TAGCTGTACA CCAATGGCTG ATCTGGGACT GGATGCTTTG 2100

GAAGATTGGT CAGCTCACAT CCCCAGGCAT ATCATGCAAC CTTATTACAA GGATGTGCTA 2160

CCTCTTCTTG ATGGTTATTT GAAAAACTCT GCAACTGCAG TTGAACCCCA AAATAACTGG 2220

GAAGTAAGGA AGCTTTCCCG AGCAGCCCAG AAAGGATTTA ACAAAATTGT GATACAGCGT 2280

TTAAGAAAAG CAAAAACTTC TTCATTGGAT GACAGTCCCT CCTTAGAAGG AGTAAGGACT 2340

AGAGTGGCTC GCCTTCTTGG GTCTTTAGGA GGGCAGATCA ACCACAACTT AATTACAGCC 2400

ACCTCTGCAG AAGAGATGAT GAAGAAATGT GTGTCCTGGG ACACCGAGAA CCACCTGAGC 2460

TTTGCTGTGC CATTTGCAGA CATGAAGCCT GTCATCTACT TGGATGTGTT TCTGCCTCGT 2520

GTGACTGACC TGGCTCTTTC TGCAAGTGAC AGGCAAACAA AGGTTGCAGC ATGTGAACTG 2580

CTACATAGCA TTGTTGCATA TATGCTGGGG AAAGCATCTC AGATGCCAGA AAGACAACAG 2640

GGTTCACCAC CCATGTATCA GTTATACAAA CGAATATTTC CAGTACTACT TCGTCTTGCC 2700

TGTGATGTAG ACCAGGTTAC GAGACAGTTG TATGAGCCTT TAGTCATGCA GCTCATTCAC 2760

TGGTTTACAA ACAACAAGAA ATTTGAGAGT CAAGATACAG TGACGTTTCT GGAAGCCATC 2820

TTGAGTGGCA TAGTGGATCC AGTTGACAGC ACTCTGAGAG ATTTCTGCGG TCAGTGTGTA 2880

CGAGAATTTT TGAAGTGGTC TATTAAGCAG ACAACACCGA GACAGCAGGA GAAAAGCCCA 2940

GCAAACACCA AGTCTCTTTT TAAAAGATTA TATAGTCTTG CTCTTCATCC CAGTGCTTTC 3000

AAGAGACTAG GTGCAGCACT TGCTTTTAAC AGCATCTACA GAGAATTTAG GGAAGAGAAT 3060

TCTCTGGTGG AACAGTTTGT ATTTGAAGCA TTGGTGGTAT TTCTGGAAAG TCTGGCTTTA 3120

ACCCACACAG ATGAGAAATC ATTAGGTACC ACCCAACAAT GTTGTGATGC TATTAATCAC 3180

CTGAAGCGCA TAATCAAGCA TAAAGCACCT GCTCTGAATA AGGAAGGAAA ACGGCGGGTA 3240

CCACGGGGAT TTCCAGCTAC TAAGTCAGTG TGCCTTCAGG ATGTTGTCAT GTGGCTCTTA 3300

GTACAGTGTG GACGACCTCA GACGGAGTGT CGACATAAAG CCATGGAGCT CTTTTATGAA 3360

TTTGTTCCTT TATTGCCAGG AAACAATTCT CCATCTTCTT GGCTGGCTGA TGTTTTAAAA 3420

AAGAAAGATG TTTCCTTCCT TATTAACAAA TTTGAAGGAG GTGGCAGTGA TGCCGAAAGC 3480

CCATCTGGGA TTCTTTCTCA GCCAACTCTC CGTAATATGC AGGAGCCCTT TAGTTTACCG 3540

ACTGTCATGC GGTGGATGGA CATGTTCTTA GCAGCACTGG ACTGCTACAA TACTTTCTTT 3600

GAGCTGCGAA TGATCAAGCC TCATGAAATA CTGGGTGTAA ATGACAGGTC CTCATTCTTG 3660

GAAGCAGTGG ATTTCTTCCT TGAAACTATT GCCTTGCATG ATATTCATGC AGTGGAGCGG 3720

TGCTTTGATT GCAGATTGAG AGGCAACATA TTCAGTCCTC AAGAGAGAGA AATGTATAAT 3780

TACAGTAAGT GTACAATTAT CGTGCGAATC ATGGAGTTTG TCACCATGAT CCTGGAAACA 3840

TGCCAGCAGG ATTTCTGGAA GCTACTTGAG AAGGAATTGC TTAATGCAAA CTTTGTAGAG 3900

CTTCTGGTGA TGACAGTGTG TGATCCATCA CATATAGGAT TTAATACAGC TGATGTACAA 3960

GTCATGAAAA ATCTCCCAGA TATCTCAGTG AGACTCTTGA AAGCTTTGAT GAAATCTCCC 4020

TGTAAAGAAT ATTTGCAATT ATGTTTAAGA AAAAGAATCA CACCGCAGAG CTTTGAGGAC 4080

CTTTTTTCTG TTGATCTGTT CAATTCAGAT GAGCGTTTCG ATCAAGTTAG GTTTAGTGCT 4140

GTTCTTTCTG CCTGCAAGCA ACTCCAGAAA TCTGGTCTAC TTCATTCTGT TCTTCACAAT 4200

CAGGGTGAAA GGCCTCATCC CTCAATTGGC TCTAAGCTTC TTTCGGTTGT TTATAAAGGC 4260

ATTGCACCTG GGAGTGAAAG GAGCTCTCTT CCAGCAGTAG ACATCAGCAG TAAGCGATTA 4320

GCTGATAGAC TCCTGCAGCT TGCCTTTGCC ATTGATGACC AGTGTGAGGA GCTAGTAAGT 4380

CTGCTGTTGA ACACGGTGGT GTTATCTGTG CCATTATCCG AAGCCTCAGA GAGAAACTTT 4440

GTTAATTTTT CTCATGGACA GTATTTCTAC AGCCTGTTCT CAGACACCAT TAATCAGCAG 4500

CTGCTAAAAA ATCTGGATGT GATAGTAATC CAGCTTATGG AATCATCTGT CAGCAATCCC 4560

CAGATGGTTG GAAGCATTTT GAATGGCATG TTAGATCAGA GTTTTAGGGA GCGTACCATA 4620

CGCAAGCAGC AAGGAGTGAA ACTGGTCACA GCAGTACTGA GAAACTGGAA GAGGCTTGAC 4680

AGTTGGTGGG CCAAAGATAG TCCTTCTAAA ACCAGAATCG CAATATATGT ACTTTCTGTT 4740

CATTCATTGC AGATAGACTC TTCAGTTTCT TTCAATACCA GTCATGAAGC ATTTACAGCT 4800

GTTTTTGATA CCTATACCAG TCTACTTACT GATCAGAATT TAGGCTTAAA TCTGAAAGGC 4860

CAGGCAGTGA TAATTCTTCC ATTCTTCACT AATTTGACTG GAGAAAAACT TAATGAACTT 4920

AAGAATGCTC TTGATCAACT TGTAGCTTTC AATTTTCCTA TGAGTTCAGA TGAGTTTCCC 4980

AGAGGAACCT TGAAGCACAA TAACTATGTG GACTGCACTA AGAAGTTTTT AGATGCTTTA 5040

GAGTTGTCTC AGAGTCCAAT GTTGTTGCAG TTGATGACAG AAATCCTCTG TAGGGACCAT 5100

AGACATTCTA TGGAGGACTT ATTTCAAGCC AGCTTCAAAA GAATTTCCAG AAGGAGCAGC 5160

ACTGACAAAC AAGTGGTACT GCTGGACACT GTTCACAAGA TGTTCCAGAA TGAAGACCTT 5220

CTTTCAAATA CTGTCCGTCA AGCTTTTGTG GATCGCTCTC TCCTCACTCT CATGTCACAC 5280

TGCAGCTTGG ATGCTTTGAG AGAGTTTTTT TGCAAGATTA TAGTGCAGGC TATGGATACA 5340

CTTAATTCCA GGTTTACAAA GTCCAATGAA TGTGTTTTTG ATACACAAAT CACCAAGAAA 5400

ATGGGTTATT ACAAGCTGCT GGAAGTGATG TATATACGTC TTTCAAAAGA GGATGTTCAC 5460

TCCAAGGACT CTAAAATTAA CCAAGCTTAC CGTGGCTCTG TAAGTGTAGA AGGAAATGAA 5520

CTTACCAAGG CACTAATAAA GTTGTGCTAT GATGCATTTA CAGAAAACAT GGCAGGGGAG 5580

AGTCAACTGC TGGAGAAGAG GAGACAGTAT CACTGTGCAG CATATAATTG TGCTATTGCT 5640

GTTATTAGTT GTGTCTTCAC TGAAAGTAAA TTTTATCAAG GCTTTCTCTT TACAGAAAAA 5700

TCAGAAAAGA ACTTGCTGAT TTTTGAAAAC TTGATAGACT TGAAGCGTCA GTACATGTTT 5760

CCTGTAGAAA TTGAGGTTCC CCTGGAAAGG AAGAAAAGAT ACATTGCTAT TAGAAAAGAA 5820

GCCAGAGAGG CATGGAATGA TGGTCAGGAT GAACCCAAGT ATTTAGCTTC TGCATCATAC 5880

ATGATGGATA GCAGTTTGAG TGAGGAAATG AGTCAGTTTG ATTTTTCTAC TGGAGTCCAA 5940

GGTTTTTCTT ATAGCTCCCA GGATGTTACA GCTAGCAGTG CTCACTTCAG GAGAAAGGAG 6000

ATGTCAGAAT ACATGGTTTT AAATGATGAG TTGGAACTGG AGATGGATGA ACTTAACCAA 6060

CATGAGTGTA TGGCACCAAT GACCACTCTG ATTAAGCATA TGCAGAGGAA CCAGATCACA 6120

CCCAAAGTGG AAGAGGGCGT GGTTCCTGTA GACCTCCCTC TTTGGATGAA ATTTCTGCAT 6180

AGTAAGTTAG GAAATCCGTC AGTGCCATTA AATATTCGCC TCTTCATAGC AAAACTTATT 6240

GTTAATACTG AGGATGTTTT CCGACCCTAT GCAAAGCAGT GGCTTGGTCC GATGCTGCAG 6300

CTTGTTGTTT CTGGCAATAA TGGAGGTGAA GGGATTCATT TTATGGTAGT GGAAATAGCA 6360

GTTACCGTTC TTTCCTGGAC GAGTGTAAAT ACTCCCAAAG GAAATATTAA GGATGAGATT 6420

TTGGCTAACA GATTGCTTGA ATTCTTAATG AAGAATGCCT TTCATCAGAA ACGAGCTGTG 6480

TTCAGACACA ACCTGGAAAT CATAAAGACA GTTATAGAGT GTTGGAAGAA CTGTCTCTCC 6540

ATACCTTACA GCTTAATATT TGAAAAGTTT TCTAGTGAAG ATCCTGATAC AAAGGACAAC 6600

TCAGTGGGAA TTCAGCTGCT GGGAATTGTT CTGGCTAACA ATTTACCTCC CTATGACCTG 6660

AAGTGTGAAA TAGATCGTGT CAGGTATTTT CAGGCTCTGA TCAGTAACAT GGGTTTATTA 6720

AGGTATAAAG AAGTTTATGC AGCTGCAGCA GAAGTGTTGG GACTTGCTCT TCAGTATATA 6780

GCTGAGAGAC AAAATATACT TGAAGATCCA GTTTATGATT GTGTCATAAA ACAATTAAAA 6840

CATCATCAGA ACACTCAACA GGATAAGTTT ATAATATGCT TGAATAAAGT TGTTAAGAAT 6900

TTTCCTCCTC TTGCTGACAG GTTTATGAAT GCAGTATTCT TTTTAATACC AAAACTTCAC 6960

GGTGTGATGA AAAACTACTG TCTGGAAGTA ATTATGTACC GAGCAGAGGA AATACCTGAT 7020

CTCTATCTGC AGTTAAAGAG TAAAGACTTC ATCCAGATCA TGAAACACAG GGATGATGAA 7080

AGGCAAAGGG TTTGTTTGGA TATAATATAC AAGATGCTGT CTACACTGAA ACCACCAGAA 7140

CTTAAAGAAC TTCTTCCTGG AGTGACAGGG TTCATTTCTC ACCCTTCTGT AATATGTCGA 7200

CAGCGCATGT ATGATATTCT GATGTGGATT TATGATAATT ACAGTGATCC AGAAAGCCAA 7260

GCAGGTGATG ATTCTCAGGA AGTGCATGGA CTGGCAAAAG AAACCCTGCT TCAGGGTCTG 7320

ATTGATGAGA ATGCTGAACT GCAATTAATT GTTAGGAATT TTTGGAGTGA CGAGACAAGA 7380

TTACCTGCAA ATATTCTTGA TCGTATGCTG AAGTTGTTAA GTTCTTTATA TTCTGCCAAG 7440

ATTGAAACAC AGTACTTGAG TCTGATCACA AATTTTCTGC TTGAAATGAC CAGCAAAAGC 7500

CCAGATTATT CCAGGAAAAT ATTTGAGCAC CCACTATCTG AATGCAAATT TCAGGACTTT 7560

GTAATTGATT CCAGTTGGCG TTATCGAAGT ACCATTCTCA CACCTATGTT TGTGGAGACT 7620

CAGGCTTCAC AGAGTACTAA CAGGAATTCA TCACAAGAAA AATCCCTTTC CATTTCTGGG 7680

TCAGTAGGTG GTCGAGTGAG AGCTACCCAA AGGCAATATG AATTTACACC TACGCAAAAT 7740

GTTGGTGGTA GAAGTTCTTT TAATTGGCTA ACTGGAAACA GCATTGACAC TTTGGCGGAG 7800

TATACAGTTC CTTCTTCCTC TGAGTCTTTG TCTTCATCCA TGCTGTTAGT TAACAAACGG 7860

AGTGAAAAAT TTAAACCTGT GGGGCCAGAT TTTGGGAAAA AAAGGCTGAG TTTACCTGGA 7920

GATAAAGTGA ACAGCAAAAC TAAAGGTATA GATGAACGAG CAGAAATTTT AAGACTGCGG 7980

AGGCGTTTCT TGAAGGACCA AGAGAAAGTC AGTCTGATTT ATGCTAGAAA AGGTGTGGCT 8040

GAACAGAAAA GAGAAAAGGA GATGAAATCT GAGCTGAAGA TGAAGTTTGA TGGCCAGGTT 8100

ACTTTGTACA GAAATTACCG TGTAGGAGAC CTTCCTGACA TCCAGATTGA ACACTCCAGC 8160

CTCATTGCCC CTCTACAGGC CCTTGCCCAG AAAGATCCAA CATTTGCCAA GCAACTTTTC 8220

AGCAGTTTGT TTGCTGGAAT TTTTCATGAG GTGAAAAAAT CTAAAACTCT TTCTGAGAAA 8280

AAAGTCATCA TCCAGAAGCT GCTGAAGGAC TTCAATCATT TCCTTAGTAC AAGCCTTTCT 8340

TACTTCCCAC CATTCATTGC GTGCATCCAG GAGATAAGTT ACAAGCACAG AGAGCTGCTG 8400

GAGCTGGATT CAGCTATCGT GAGCACGAGC TGCCTTGCAA GCCTACAGCA GCCCGTAGGC 8460

ATCCTCCTTC TGGAGCACGC CCTGATGGCA CTGTCCCCTG CAGAGGAGCC CCCGTCAAAG 8520

CGGATGCGCG GCAGGATGGA GCTCCCCCCT GATGTCATCA AGTGGCTTGA GCTTGCAAAG 8580

CTTTACCGGT CTCTGGGAGA TTATGATGTC CTTCGTGGTA TTTTCAGTGG TAAGATTGGG 8640

ACTAAGAAAA TAACACAGCA AGCATTGCTG GCAGAAGCAA GGAGTGATTA TGCTGAAGCA 8700

GCTAAATGTT ATGACGAGGC ACTGTCCAAA GAAGACTGGG AAGATGGGGA CCCAACTGAA 8760

GCAGAGAAAG ACTTCTGGGA ACATGCATCT CTGGAATGCT ATGACCACCT CACAGAGTGG 8820

AAGTCTCTGG AGTATTGTGC TACTGTTAAT ATTGACAGTG GTAAACCTCC AGACCTGAGC 8880

AAAACATGGA ATGATCCATT TTATCAGGAG ACATATCTGC CCTATATAAT ACGCAGTAAG 8940

CTGAAGCTGC TGCTCAGTGG GGAAAATGAC CAGACTTTGT TGACTTTCAT TGATGAGGCA 9000

ATGAAGACAG AACAGAAGAA AGCTCTGATA GAAATGCATT ACAGCCAAGA GCTTAGTCTC 9060

CTTTACATCC TGCAAGATGA TTTTGACAGA GCCAAATATT ACATTGGCAA TGGCATGCAG 9120

ATCTTCATGC AGAGCTATTC TAGTATTGAT ACTTTGTTAT ACCAAAGTCG AATGAGCAAA 9180

CTGCAGTCTG TACAAGCTTT GACAGAAATA CAGGATTTCA TCAATTTTAT GACCAAAACA 9240

AGTAACTTAA CTTCACGGGC TAAATCCCTG AAGAGACTTC TCAGAACTTG GACAAGCAGA 9300

TATCCAGATG CTAAAATGGA TCCCATGAAC ATCTGGGATG ATATCATTAC AAATCGGTGC 9360

TTCTTTCTTG ACAAGCTGCA AGAGAAATTT CTCTGTGATC AGGCCAATGA TAGTATGGAG 9420

GTGGATGAAG AAAGTGGTGT TGGAGACCAA ATGGAAGTAG ATCAACAGGA TGAAGACATT 9480

CACTCAATGA TTAGAAGCTG CAAATTTAAC ATGAAACTGA AGATGATAGA AAGTGCCAGG 9540

AAACAGAACA GCTTCTCTGT TGCCAAGAAG CTGCTGAAGG ACCTGCGCAG AGAGGCCAGA 9600

ACGAGGGAGG ACTGGCTGGT GAGGTGGAAC TGTGCCTACT GCCGCTTCGT GCATAGCTGC 9660

AGCCAGAGCC AGAGTTGTCC TGAACGAGTG CTTTCTGTCT TAAAAACCAT CTCCCTACTC 9720

GAAGATACCA AGTCAGACTA CCTTAACGAG AACATAATGG CCTTCCGAAA CCAGAATCTT 9780

CTGCTGGGTT CTACGTACCA CATCATGGCC AATGCTCTTA GTCAGGATCC CAAATGCTTT 9840

GAGCAAATAG AGGAGGAAAA AGCTGGGAAA ATATTGGAAC TGTCAGGAGA AAGTTCTGAG 9900

AGTCCTGAAA AGATATTAGC AGGTCTGAAC AAGAGAGCTT TTCAGTATTT CAGCAGTGCT 9960

GCAAGGAAGT CTGAAGAGGA AGTGCAGTCC CTCTCCATGG AACACATTGA TGTGAAGGGA 10020

GTTATCGATG CATATATGAC TTTGGTTGGT TTCTGTGACC AACATCTGCG TAAGGAAGAA 10080

GAAGGCTCAC TTGAAATTAA CGCTGCAGAT CTGCAGCTAT TCCCAGCTAT TGTGGTGGAG 10140

CAAATGATAA AAGCTTTAAA ACTGAACTCC AGAGAAGCCA GGCTAAGGTT TCCTCGACTG 10200

CTACAAATAA TTGAAAGATA TCCAGCAGAG ACTTTGGGTC TGGTGACACG AGAGCTTTCT 10260

TCAGTTCCCT GCTGGCAGTT CATCGGTTGG ATTAGCCAGA TGATGGCACT CCTTGACAAG 10320

GATGAAGCAG TGGCTGTGCA GCACACTGTT GAAGAGATCG CAGATACCTA CCCCCAGGCA 10380

ATCATCTACC CGTTCATGAT CAGCAGCGAG AGTTTCTGCT TCAAAGATAC TGCAGCAGGC 10440

TGTAAGAACA AGGAGTTCGT AGCAAGCATC AGGAACAAGT TGGACAGAGG AGGAGTAGTT 10500

CAAGATTTTA TTCACTCCCT GGAACAGCTT TCTAATCCTG TAATGCTTTT TAAGGACTGG 10560

GTTGAGGATG TCAGAAATGA ACTGGTAAAA GCTCAGAGGA ATAAAATTAA ACTTAGGGAA 10620

ATGTATGAAA GAATGTACAA GAATTTGGGA GATGCGAAGG CTCCTGGCCT TGGATGGCTG 10680

AGGAAACAGT TTGTTCAGGC TTTTGGGAAG GATTTTGACA GTCATTTTGG AAAAGGTGGT 10740

TCAAAGCTGT TGGATATGAA GGCCAGTGAT TTTAATGAGA TCACAACATC TCTTCTCACA 10800

AAAATGAACA AAACCCATAA AGAACCTGCA AACCTGAAAG AGTGTTCACC ATGGATGAGT 10860

GAATTCAGAG CTGAGTTCTT GAGGAATGAG CTGGAGGTCC CTGGTCAGTA CGATGGGAAG 10920

GGAAAACCTC TGCCAGAGTA CCATGTGAAG ATCTCTGGGT TTGATGAACG GATAATGGTA 10980

TTGGAATCCT TGAGGAAACC CAAGCGCATA ACAATCCGAG GCAGCGATGA GCAGGAGCAC 11040

CCTTTCCTTG TCAAAGGTGG AGAAGACCTG CGACAAGACC AACGCATTGA GCAGCTCTTT 11100

GATGTAATGA ACATCGTCCT TTCCCGAGAC GCTGCCTGCA GCCAAAGGAA TATGCAGTTG 11160

AAAACTTACC AGGTCATCCC CATGACCACA AGACTGGGAC TCATCAAGTG GCTGGAAAAT 11220

ACCTGTACTT TGAAAGAATT CCTGAGGAAT AGCATGACTG AAGAGGAGGA CACCAAATAT 11280

AATAGCCAAA AAGGACCTCG TGCTGCCTAT TCTGACTGGC TGTCCAAAAT GGGTGGGAAG 11340

GCACAAGGCT TATCTCGATA CTCTGCTATG TACAAAAATG CAAGCCGCAC AGAAACAGTT 11400

ACTGCCTTCA GGAGCAGGGA GAACAGTGTT CCAGAAGATC TGCTGAGGAG AGCCTTTGTG 11460

AAGATGAGCA CATCTCCTGA AGCTTTCCTG GCTCTGCGGT CGCACTTTGC CAGCTCGCAC 11520

GCACTGATGT GCATCAGTCA CTGGATACTC GGAATTGGAG ACAGGCACCT GTCCAACTTC 11580

ATGATTAACA AGGAGACGGG TGGCATGGTG GGAATAGACT TCGGGCATGC GTTTGGCTCA 11640

GCCACACAGT TTCTGCCCGT GCCGGAGCTG ATGCCTTTCC GCCTGACGCG CCAGTTTGTG 11700

AATCTGATGA TGCCAGTGAA GGAGTGGGGC CTCATTTACA GTGTGATGGT GCATGCCCTG 11760

AGAGCATACC GTGCGGATCC CGATCTCCTC ATCAGCACAA TGGATGTGTT TGTAAAAGAG 11820

CCTTCCCTGG ACTGGAAGAA CTTTGAACAA AGGCAGCTGA AAAAAGGAGG CACGTGGATT 11880

AAGGAGATAA ACACTGCTGA AGTAAACTGG TACCCTTTGC AAAAAATCAG CTATGTCAAA 11940

AGGAAACTTA CAGGTGCCAA TCCTGCACGA ATCACTTGTG ATGAGCTGCA CCTGGGCTAT 12000

GAGAAGTCAC CTTTTTACAA TGACTTTGCA GCTGTTGCTC GTGGCAGCAC TGACCATAAT 12060

ATCAGAGCCA AAGAGCCAGA GGATGGACTG TCTGAGGAGA CCCAGGTGCA GTGCCTGATA 12120

GACCAAGCAA CGGACCCCAA TGTCCTCGGC AGGGTGTGGG AAGGATGGGA ACCTTGGATG 12180

TGA 12183

Domain Profile

S: 1     iagfderveilaskqkpkklllrGsdgkeypyLvkgkeDlrqdervlqlfslvNtlLakd  60

         i gfder+ +l+s++kpk++++rGsd++e+p+Lvkg eDlrqd+r++qlf ++N +L +d

Q: 3651  ISGFDERIMVLESLRKPKRITIRGSDEQEHPFLVKGGEDLRQDQRIEQLFDVMNIVLSRD  3710

         789*********************************************************

S: 61    ketsrrkLkirtykVvplstrsgliewventvsLkellkkl.vekkavlldqpi..syry  117

         +++s+r+++++ty+V+p++tr+gli+w+ent +Lke+l++   e+++ ++++++  +  y

Q: 3711  AACSQRNMQLKTYQVIPMTTRLGLIKWLENTCTLKEFLRNSmTEEEDTKYNSQKgpRAAY  3770

         ***************************************986777888887766788999

S: 118   kdlstvqarkpk.lkhlkls.........levfkevlenlvpkdllkklllekfpspeew  167

          d+  ++  k + l+ ++ +         ++ f+ +++  vp+dll+++++++++spe++

Q: 3771  SDWLSKMGGKAQgLSRYSAMyknasrtetVTAFRSRENS-VPEDLLRRAFVKMSTSPEAF  3829

         99998887743324555555666888899******9999.********************

S: 168   felrkaytrslAvislvgyiLgLgdrhlenllidqetgevvhidfgvafekaktqlkvpe  227

         ++lr+++++s+A+++++++iLg+gdrhl+n++i++etg +v idfg+af++a+++l+vpe

Q: 3830  LALRSHFASSHALMCISHWILGIGDRHLSNFMINKETGGMVGIDFGHAFGSATQFLPVPE  3889

         ************************************************************

S: 228   kvPFRLTrnivnalgvtgveGvfrasceavlrvlreskeklltiLevflydplvdwkk..  285

          +PFRLTr++vn++ ++++ G++++ ++++lr+ r +++ l ++++vf+++p++dwk+

Q: 3890  LMPFRLTRQFVNLMMPVKEWGLIYSVMVHALRAYRADPDLLISTMDVFVKEPSLDWKNfe  3949

         ************************************************************

S: 286   ....kkktsketeeelaekakaealkikkllskvekaenavatrdllll  330

             kk++++++e++ ae ++++ +ki ++++k+++a++a +t+d+l l

Q: 3950  qrqlKKGGTWIKEINTAEVNWYPLQKISYVKRKLTGANPARITCDELHL  3998

         ***99***************************************98765

Domain Sequence
(FASTA)

ISGFDERIMV LESLRKPKRI TIRGSDEQEH PFLVKGGEDL RQDQRIEQLF DVMNIVLSRD 60

AACSQRNMQL KTYQVIPMTT RLGLIKWLEN TCTLKEFLRN SMTEEEDTKY NSQKGPRAAY 120

SDWLSKMGGK AQGLSRYSAM YKNASRTETV TAFRSRENSV PEDLLRRAFV KMSTSPEAFL 180

ALRSHFASSH ALMCISHWIL GIGDRHLSNF MINKETGGMV GIDFGHAFGS ATQFLPVPEL 240

MPFRLTRQFV NLMMPVKEWG LIYSVMVHAL RAYRADPDLL ISTMDVFVKE PSLDWKNFEQ 300

RQLKKGGTWI KEINTAEVNW YPLQKISYVK RKLTGANPAR ITCDELHL 348

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0003677	; F:DNA binding
GO:0004677	; F:DNA-dependent protein kinase activity
GO:0006303	; P:double-strand break repair via nonhomologous end joining

KEGG

InterPros

IPR016024	; ARM-type_fold.
IPR003152	; FATC.
IPR011009	; Kinase-like_dom.
IPR012582	; NUC194.
IPR000403	; PI3/4_kinase_cat_dom.
IPR018936	; PI3/4_kinase_CS.
IPR003151	; PIK-rel_kinase_FAT.
IPR014009	; PIK_FAT.

Pfam

PF02259	; FAT; 1.
PF02260	; FATC; 1.
PF08163	; NUC194; 1.
PF00454	; PI3_PI4_kinase; 1.

SMARTs

SM00146

; PI3Kc; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS00915	; PI3_4_KINASE_1; 1.
PS00916	; PI3_4_KINASE_2; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013