EKS-MEG-00321

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MEG-00321

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE11	358.2	2.6E-107	370	629	260

Status

Unreviewed

Ensembl Protein

ENSMGAP00000012262

UniProt Accession

G1NGN6;

Protein Name

Protein Synonyms/Alias

Gene Name

MAP3K2

Gene Synonyms/Alias

MAP3K2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMGAG00000011696	ENSMGAP00000012262	ENSMGAT00000013151

Organism

Meleagris gallopavo

Functional Description

Protein Length

632

Protein Sequence
(FASTA)

ADEQQALNSI MQDLAVLHKA SRPALPQQET GKPKSSSPKK QNDVRVKFEH RGEKRILQLP 60

RPVKLEDLVA KAKVAFGQTM DLHYCNNELV IPLTTQDDLD KAVELLDRSV HMKSLKILLV 120

IHGNTQTAAS VLIGFCVMSP SVNNVEPLPS LEDLDNTVFG VTERKRRLSV LGSNNRDRSS 180

PPPGYIPDEL HQVARNGSFT SINSEGEFIP ESMDQCMLDP LSLSSPENSG SGSCPSLDSP 240

LDGDNYPKSR MPRAQSYPDN HQEFSVDYDI PIFEKFGKGG TYPRRYHISY HQQDYNDGRK 300

TFPRARRTQG NSFRFSPTDH SLSTSSGSSV FTPEYEDNRM RRRGSDIDNP TLTVMDISPP 360

SRSPRAPTNW RLGKLLGQGA FGRVYLCYDA DTGRELAVKQ VQFDPDSPET SKEVNALECE 420

IQLLKNLLHE RIVQYYGFLR DPPERTLSIF MEYMPGGSIK DQLKSYGALT ENVTRKYTRQ 480

ILEGVLYLHT NMIVHRDIKG ANILRDSAGN VKLGDFGASK RLQTICLSGT GMKSVTGTPY 540

WMSPEVISGE GYGRKADIWS VGCTVVEMLT EKPPWAEFEA MAAIFKIATQ PTNPQLPPHV 600

SDHARDFLKR IFIEAKLRPF ADELLRHTFA HY 632

Nucleotide Sequence
(FASTA)

GCAGATGAGC AGCAAGCTTT GAATTCAATC ATGCAGGATT TGGCTGTGCT TCATAAGGCC 60

AGTCGTCCTG CACTGCCCCA GCAAGAAACA GGAAAACCAA AGTCATCTTC ACCTAAAAAA 120

CAGAATGATG TTAGAGTCAA ATTTGAACAT CGAGGTGAAA AAAGGATACT CCAATTACCC 180

AGGCCTGTCA AACTTGAAGA TCTTGTAGCT AAAGCTAAGG TTGCGTTTGG ACAGACTATG 240

GATTTACATT ACTGCAATAA TGAGCTTGTA ATTCCGTTAA CCACACAAGA TGACCTGGAC 300

AAAGCTGTTG AACTACTTGA CCGTAGTGTT CACATGAAGA GTCTCAAGAT ATTGCTTGTA 360

ATACATGGAA ATACACAGAC CGCAGCCTCT GTATTGATAG GATTCTGTGT AATGTCACCC 420

AGTGTAAATA ACGTGGAACC CCTTCCCTCA CTGGAAGATT TAGATAATAC AGTGTTCGGT 480

GTGACAGAAA GAAAAAGGAG GCTTTCTGTA TTAGGTTCTA ATAATCGTGA TAGGAGTTCG 540

CCTCCCCCAG GCTACATTCC AGATGAGCTG CATCAGGTGG CTCGAAATGG GTCGTTCACC 600

AGTATCAACA GTGAGGGTGA ATTCATTCCA GAAAGCATGG ATCAGTGTAT GCTGGATCCA 660

CTGTCTTTGA GCAGTCCTGA AAATTCTGGC TCAGGAAGCT GTCCCTCACT TGACAGCCCT 720

TTAGATGGAG ACAACTATCC CAAATCTCGG ATGCCGAGAG CACAGAGCTA TCCAGATAAT 780

CATCAGGAAT TCTCAGTAGA TTATGATATC CCAATATTTG AGAAGTTTGG AAAGGGGGGA 840

ACTTATCCCC GAAGATATCA TATTTCATAT CATCAGCAAG ATTACAACGA TGGTCGTAAA 900

ACTTTTCCAA GAGCCAGGAG GACGCAGGGG AACAGCTTCC GTTTCAGTCC CACTGATCAC 960

TCGCTGAGCA CCAGTAGTGG GAGCAGTGTC TTCACTCCAG AATACGAGGA TAACAGAATG 1020

AGGAGAAGAG GAAGTGACAT TGACAATCCT ACCTTGACAG TCATGGACAT CAGCCCACCC 1080

AGTCGCTCAC CACGAGCTCC AACTAATTGG AGACTTGGCA AACTGCTGGG TCAAGGTGCA 1140

TTTGGCAGAG TGTATCTGTG TTATGATGCT GATACCGGAA GAGAACTGGC TGTTAAACAA 1200

GTACAGTTTG ATCCTGATAG TCCAGAAACT AGCAAGGAAG TAAACGCTCT TGAATGTGAA 1260

ATTCAGTTGC TGAAAAATCT GCTGCATGAG AGGATCGTTC AGTATTACGG CTTCCTGAGG 1320

GACCCACCAG AAAGAACACT CTCTATATTC ATGGAATACA TGCCAGGGGG GTCCATCAAA 1380

GACCAATTAA AATCGTATGG AGCACTCACA GAGAACGTGA CTCGCAAATA CACACGGCAG 1440

ATTCTGGAAG GAGTTCTCTA TTTGCACACA AATATGATTG TCCATCGAGA TATTAAAGGA 1500

GCAAATATTC TGCGAGATTC AGCAGGCAAT GTGAAGCTGG GTGACTTTGG TGCCAGCAAA 1560

CGACTGCAGA CCATCTGTCT GTCTGGTACA GGAATGAAGT CTGTCACGGG AACTCCGTAC 1620

TGGATGAGTC CAGAAGTTAT CAGTGGAGAA GGGTACGGCA GAAAAGCAGA TATCTGGAGC 1680

GTAGGTTGTA CAGTGGTAGA AATGCTCACT GAGAAGCCCC CATGGGCAGA ATTTGAAGCA 1740

ATGGCTGCCA TCTTTAAGAT TGCCACTCAG CCAACCAATC CCCAGTTACC ACCTCATGTC 1800

TCAGACCATG CTCGGGATTT CCTGAAAAGG ATTTTTATCG AGGCCAAGCT GCGACCATTT 1860

GCAGATGAAC TGCTAAGACA CACGTTTGCA CACTAT 1896

Domain Profile

S: 1     wqkrevigkGsfgsvyaaldvdtgellavKeveikpekksekkevkalkeEikllkelkH  60

         w+ ++++g+G+fg+vy+++d+dtg+ lavK+v+++p++ +++kev+al++Ei+llk+l H

Q: 370   WRLGKLLGQGAFGRVYLCYDADTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLH  429

         78899*******************************************************

S: 61    enivkyyGv..eveeeelkiflEyvegGslssllekygkleesvikkytkqileglayLH  118

         e+iv+yyG+  +  e++l+if+Ey++gGs++++l++yg+l+e+v++kyt+qileg+ yLH

Q: 430   ERIVQYYGFlrDPPERTLSIFMEYMPGGSIKDQLKSYGALTENVTRKYTRQILEGVLYLH  489

         *********6566799********************************************

S: 119   ekkivHRDiKgaNilldssgvvklsDFGaskrlaelntkaaelesltGtlaymaPEvikk  178

          ++ivHRDiKgaNil ds+g+vkl+DFGaskrl++++ + + ++s+tGt+++m+PEvi++

Q: 490   TNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISG  549

         **********************************************************99

S: 179   kekgygrkaDiWslgcvviemltgkrPfaeldeelaimfkvgakktkPeipeklseegkd  238

         +  gygrkaDiWs+gc+v+emlt+k+P+ae+ e++a++fk++++ t+P++p ++s++++d

Q: 550   E--GYGRKADIWSVGCTVVEMLTEKPPWAEF-EAMAAIFKIATQPTNPQLPPHVSDHARD  606

         8..****************************.9***************************

S: 239   flekcleldpkkrpsaeeLLkhef  262

         fl++++ +++k rp a+eLL+h+f

Q: 607   FLKRIF-IEAKLRPFADELLRHTF  629

         ******.899************99

Domain Sequence
(FASTA)

WRLGKLLGQG AFGRVYLCYD ADTGRELAVK QVQFDPDSPE TSKEVNALEC EIQLLKNLLH 60

ERIVQYYGFL RDPPERTLSI FMEYMPGGSI KDQLKSYGAL TENVTRKYTR QILEGVLYLH 120

TNMIVHRDIK GANILRDSAG NVKLGDFGAS KRLQTICLSG TGMKSVTGTP YWMSPEVISG 180

EGYGRKADIW SVGCTVVEML TEKPPWAEFE AMAAIFKIAT QPTNPQLPPH VSDHARDFLK 240

RIFIEAKLRP FADELLRHTF 260

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity
GO:0071260	; P:cellular response to mechanical stimulus
GO:0045893	; P:positive regulation of transcription, DNA-dependent

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000270	; OPR_PB1.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF00564	; PB1; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00666	; PB1; 1.
SM00220	; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013